Chapter1
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Anatomy is the study of body structure, physiology is the study of how the body functions, and pathophysiology describes the consequences of improper body functioning. Homeostasis maintains a stable internal environment through negative feedback loops that detect variations from normal set points and positive feedback that enhances stimuli like blood clotting and childbirth requiring external intervention.
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Structure and function of adrenal glands
• Anatomically, the adrenal glands (suprarenal) are located in the thoracic abdomen situated 'on' top of the kidneys one on each side, specifically on their anterosuperior aspect.
• They are surrounded by the adipose capsule and the renal fascia
• They consist of two parts,
The outer cortex
The inner medulla.
Adrenal Cortex
• The adrenal cortex is devoted to the synthesis of corticosteroid hormones from cholesterol.
It completes the hypothalamic-pituitary-adrenal axis
The source of cortisol and corticosterone hormones
• The cortex is divided into three zones, or layers.
• This division is sometimes referred to as ‘functional zonation”
Zona glomerulosa
Zona fasciculata
Zona reticularis
Adrenal Medulla
• The adrenal medulla is the core of the adrenal gland, and is surrounded by the adrenal cortex.
• The chromaffin cells of the medulla are the body's main source of the circulating catecholamines, adrenaline (epinephrine) and noradrenaline (norepinephrine
Blood supply to Adrenal Gland
• Although variations of the blood supply to the adrenal glands (and indeed the kidneys themselves) are common, there are usually three arteries that supply each adrenal gland:
The superior suprarenal artery is provided by the inferior phrenic artery.
The middle suprarenal artery is provided by the abdominal aorta.
The inferior suprarenal artery is provided by the renal artery
• Venous drainage of the adrenal glands is achieved via the suprarenal veins:
The right suprarenal vein drains into the inferior vena cava.
The left suprarenal vein drains into the left renal vein or the left inferior phrenic vein
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• They are surrounded by the adipose capsule and the renal fascia
• They consist of two parts,
The outer cortex
The inner medulla.
Adrenal Cortex
• The adrenal cortex is devoted to the synthesis of corticosteroid hormones from cholesterol.
It completes the hypothalamic-pituitary-adrenal axis
The source of cortisol and corticosterone hormones
• The cortex is divided into three zones, or layers.
• This division is sometimes referred to as ‘functional zonation”
Zona glomerulosa
Zona fasciculata
Zona reticularis
Adrenal Medulla
• The adrenal medulla is the core of the adrenal gland, and is surrounded by the adrenal cortex.
• The chromaffin cells of the medulla are the body's main source of the circulating catecholamines, adrenaline (epinephrine) and noradrenaline (norepinephrine
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• Although variations of the blood supply to the adrenal glands (and indeed the kidneys themselves) are common, there are usually three arteries that supply each adrenal gland:
The superior suprarenal artery is provided by the inferior phrenic artery.
The middle suprarenal artery is provided by the abdominal aorta.
The inferior suprarenal artery is provided by the renal artery
• Venous drainage of the adrenal glands is achieved via the suprarenal veins:
The right suprarenal vein drains into the inferior vena cava.
The left suprarenal vein drains into the left renal vein or the left inferior phrenic vein
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The document discusses the adrenal gland and its hormones. The adrenal gland sits atop the kidneys and has two parts - the adrenal cortex and adrenal medulla. The adrenal cortex secretes corticosteroids like aldosterone and cortisol which regulate salt balance, blood sugar, and the immune system. The adrenal medulla secretes catecholamines like adrenaline and noradrenaline which trigger the body's fight or flight response and increase heart rate and blood pressure. In summary, the adrenal gland regulates important bodily functions through the hormones it secretes from its cortex and medulla.
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This document provides information about hormones produced by the adrenal glands and hypothalamus-pituitary axis. It discusses the major adrenal hormones including glucocorticoids, mineralocorticoids, catecholamines, and sex steroids. For each hormone, it describes the site of production, regulation, effects, abnormalities of hypo- and hypersecretion, and laboratory tests. It also summarizes the female and male sex hormones produced by the ovaries and testes, as well as placental hormones critical during pregnancy.
Enzymes in diagnosis and prognosis 3
This document discusses the use of clinical enzymology in the diagnosis and prognosis of diseases. It begins by explaining how measurements of enzyme activity in body fluids dates back to the early 1900s and measurements in serum began in the 1920s-1930s. A key development was the observation in 1955 that aspartate rises after acute myocardial infarction, marking the beginning of using changes in intracellular enzyme levels in plasma to detect tissue damage. The document then focuses on the clinical significance and diagnostic values of several heart function enzymes and liver enzymes. It provides details on normal levels, behaviors in different conditions, and diagnostic utilities of enzymes like CPK, AST, LDH, GGT, histaminase, and pseudocholinesterase for heart issues and AST
59229769 a-case-study-on-urinalysis-and-body-fluids
This document provides a case study on a 75-year old woman admitted with abdominal pain who was diagnosed with acute gallstone pancreatitis. The summary is:
1) The patient presented with intermittent right upper quadrant abdominal pain for 6 weeks along with nausea and vomiting in the past 24 hours. Laboratory tests revealed elevated pancreatic enzymes and ultrasound showed gallstones.
2) The case was identified as acute gallstone pancreatitis, which occurs when a gallstone lodges in the pancreatic duct, causing the pancreatic juices to become trapped and inflamed.
3) The anatomy of the gallbladder and pancreas was described, noting their roles in bile and enzyme production and drainage into the small intestine.
homeostatis
This document discusses homeostasis and the key organs that help maintain it. It explains that the liver, pancreas, kidneys, and brain help regulate homeostasis. The liver metabolizes toxins and regulates carbohydrate, lipid, and cholesterol metabolism. The kidneys regulate water, electrolytes, and pH. The hypothalamus regulates body temperature, heart rate, blood pressure, and circadian rhythms. Homeostasis involves sensors, control centers like the hypothalamus, and effectors like the kidneys. Positive and negative feedback loops maintain stable internal conditions. Examples of feedback include blood clotting and temperature regulation. The document also discusses glucose regulation by the pancreas and liver.
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The Indian Premier League (IPL) is one of the most prominent and lucrative Twenty20 (T20) cricket leagues in the world. Since its inception in 2008, the IPL has revolutionized the landscape of cricket by blending sports, entertainment, and commerce. This summary provides an overview of the IPL's history, structure, notable performances, controversies, and its impact on cricket and beyond.
History and Formation
The IPL was launched by the Board of Control for Cricket in India (BCCI) in 2008, inspired by the success of domestic T20 leagues like the English T20 Cup and the now-defunct Indian Cricket League (ICL). Lalit Modi, the then Vice-President of BCCI, played a crucial role in conceptualizing and launching the league. The inaugural season kicked off in April 2008 with eight franchises representing different cities in India.
Structure and Format
The IPL follows a franchise-based model, where teams are owned by a mix of corporations, Bollywood stars, and other high-profile individuals. The league originally started with eight teams, although the number has fluctuated over the years due to various reasons including expansions and terminations. As of the latest seasons, the IPL features ten teams.
The tournament format includes a double round-robin stage, where each team plays the others twice, followed by playoffs. The top four teams from the round-robin stage qualify for the playoffs, which consist of two qualifiers, an eliminator, and the final. This format ensures a highly competitive and engaging tournament, culminating in a grand finale to crown the champion.
Teams and Their Evolution
The founding teams of the IPL were:
Chennai Super Kings (CSK)
Delhi Daredevils (now Delhi Capitals)
Kings XI Punjab (now Punjab Kings)
Kolkata Knight Riders (KKR)
Mumbai Indians (MI)
Rajasthan Royals (RR)
Royal Challengers Bangalore (RCB)
Deccan Chargers (now defunct, replaced by Sunrisers Hyderabad)
Over the years, the league has seen new teams such as Pune Warriors India, Kochi Tuskers Kerala, Gujarat Lions, and Rising Pune Supergiant. The most recent additions are the Gujarat Titans and Lucknow Super Giants, introduced in the 2022 season.
Iconic Players and Performances
The IPL has attracted the best talent from around the world, with numerous iconic players making significant contributions. Some of the standout performers include:
Sachin Tendulkar (MI): The "Little Master" brought his legendary status to the IPL, winning the Orange Cap (top run-scorer) in 2010.
Chris Gayle (RCB, KXIP): Known for his explosive batting, Gayle holds the record for the highest individual score in an IPL match (175*).
MS Dhoni (CSK): Dhoni's leadership has been instrumental in CSK's success, leading them to multiple titles.
AB de Villiers (RCB): Renowned for his innovative stroke play, de Villiers has been a consistent match-winner.
Virat Kohli (RCB): The highest run-scorer in IPL history, Kohli's batting prowess is unmatched.
La
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The Golden Group is over. Can a new group step up? Two years ago, Kevin De Bruyne plunged Belgium’s Euro 2024 plans into disorder when he claimed the team was “too old” to win in an interview with The Protector. That Belgian squad had 10 players over 30 and the maximum average age of any Euro Cup 2024 team at the competition. A group-stage exit and just one goal at the World Cup put Belgium on course for a restructure.
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Belgium vs Romania Tickets | Euro Cup Tickets | Euro Cup Final Tickets
Coach Domenico Tedesco has managed a tactical shakeup and a regular exit for some of the oldest players. Experienced bests remain, not least the 37-year-old Jan Vertonghen in defense, the 32-year-old De Bruyne himself in midfield, and 31-year-old Romelu Lukaku up visible.
Still, younger actors like De Bruyne’s Manchester City partner Jeremy Doku bring fresh vitality to the team. Euro Cup Germany Qualifying unbeaten with just four goals allowed from eight games was a welcome sign of accomplishment back on track under Tedesco.
The only other squad in Group E besides Belgium to UEFA Euro 2024 qualify unbeaten, Romania was awestruck by winning a group that also checked Switzerland and Israel. Still, Euro 2024 will test a squad sorely lacking in top-level skill.
Euro 2024: Belgium's Transition from Golden Generation to New Hope
Tottenham guardian Vlad Dragusin is the only Euro Cup 2024 squad member singing regularly for one of Europe’s top clubs this flavor. He even played only nine Premier League games since adoption in January. Goalkeeper Horatiu Moldovan is a stoppage at Atletico Madrid.
There’s a link to the beauty days of Romanian soccer with midfielder Ianis Hagi, son of Gheorghe Hagi, who assisted the team to the rounds of the 1994 World Cup and Euro 2000.
We are only a combine of days away from the UEFA Euro 2024 curtain raiser. The 24 squads are winding up their provisions and getting ready to give it their all to life the wanted Euro Cup Final trophy on July 14. Spread across six clusters, the first hurdle in the knockout phase will be the plump of 16.
Euro fans worldwide can book Euro 2024 Tickets from our online platform, www.eticketing.co. Fans can book Euro Cup 2024 Tickets on our website at discounted prices.
Germany and Scotland will take things off before we get into overdrive in two weeks. Meanwhile, Belgium will be longing to bounce back after a horrendous 2022 FIFA World Cup movement, which ended in the group stage.
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Roberto Martinez completed the way for Domenico Tedesco, who has overseen a compact start to his tenure. The 38-year-old will be assured heading into the group stage
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3毕业证成绩单电子版做好以后发送给您确认；
4毕业证成绩单电子版您确认信息无误之后安排制作成品；
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This is an exciting platform game called Geometry Dash
Playing this fast-paced game, you control a small cube that has to get through stages that get harder by avoiding spikes, obstacles, and dangerous gaps while keeping up a fast pace. Though, it's important to remember that Geometry Dash isn't a simple game to get good at. No matter what mistake you make, you will face a tough position and have to start at the beginning.
The sounds and sights in Geometry Dash are very interesting. Your attention will be drawn to the simple style and catchy melodies. While the game looks good, it's not just visually challenging; getting through the tricky rounds requires quick thinking and reflexes.
The stages get harder over time, testing your skills and forcing you to find new ways to get past problems that other people have found impossible. Your experience with Geometry Dash will be remembered for a long time because of how satisfying it is to beat a difficult level or find a secret route. Join the many people who love Geometry Dash and are fascinated by this exciting and fun game. Get ready, because things will move quickly!
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France is among the top contenders to win Euro Cup 2024 and will rely on star forward and captain Kylian Mbappe to lead Didier Deschamps' team to success in Germany
Euro 2024 Predictions - Group Stage Outcomes
Here are our Euro 2024 predictions for the group stages
Will England make it through the group stages?, Will Germany use the home advantage to full effect?
Follow our progress, see how many we get right
If you want to join in let us know before the first game kick off and we can invite you to our private league
or join in with our friends at DeeperThanBlue
https://www.linkedin.com/posts/activity-7204868572995538944-qejG
https://www.selectdistinct.co.uk/2024/06/13/euro-2024-match-predictions/
#EURO2024 #Germany2024 #England #EURO2024predictions
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Chapter1
- 1. Anatomy
- 4. Normal range Calcium 8 – 10 mg/dl Phosphate 3 – 4.5 mg/dl Alkaline Phosphatase 20 – 70 U/L Urea 7 – 18 mg/dl