The Spanish were the first Europeans to settle in America, establishing colonies in Mexico, Central America, South America, and the southwestern United States. They had advantages over native populations due to their possession of guns and cannons, and diseases that weakened native groups. Notable Spanish conquistadors included Francisco Pizarro, who conquered the Incan Empire. The main goal of Spanish colonies was to establish Catholic missions and convert native Americans to Christianity. The French were interested in America for the fur trade and named their claimed region in the Mississippi River valley Louisiana. English joint-stock companies financed colonization efforts and the first permanent English settlement in America was Jamestown, founded by the Virginia Company.