Channel of Distribution.pdf
•
1 like•32 views
The document provides information about an individual, D. R. Chandravanshi, who is an Assistant Professor (Ad hoc) in the Department of Pharmacy at Guru GhasidasVishwavidyalaya university located in Bilaspur, Chhattisgarh, India.
Report
Share
Report
Share
Download to read offline
Recommended
Questions of Central Nervous System
The document provides 6 multiple choice questions about the nervous system: 1) The structure and functions of neurons, 2) The various lobes of the brain and their functions, 3) What the meninges are, 4) A note on the ventricles, 5) What CSF is and its functions, 6) What reflex action is and the parts of the reflex arc. Students are instructed to attempt any 5 questions worth 5 marks each.
Drug Store and Business Management (DSBM).pdf
Human life is based upon the principle of work.
▪ One has to work to earn his livelihood.
▪ Pharmacy is one of the professions.
▪ The pharmacy council of India has introduced a new subject
named “Drug store and business management”.
▪ Syllabus is divided into two parts – part I commerce and part
II Accountancy.
▪ The purpose of this subject is to familiarise the students with
the basic concept of business, its proper management, sources
of finances in order to run it successfully and the last, the way
and means to note down various transactions in books of
account with a view to having a permanent record of the same.
Channels of Distribution.pdf
Distribution is significant rated as a significant function of marketing. After
production a product moves to the market and finally to the consumer.
▪ This journey of the product from the manufacturer or producer to the consumer is
made possible through certain defined paths, termed as, “Channels of
Distribution”
Monoclonal Antibody Process.pdf
Monoclonal antibodies are antibodies that have a high degree of specificity (mono-specificity) for an antigen or epitope. Monoclonal antibodies are typically derived from a clonal expansion of antibody producing malignant human plasma cells. The initial monoclonal antibodies were created by fusing spleen cells from an immunized mouse with human or mouse myeloma cells (malignant self-perpetuating antibody producing cells), and selecting out and cloning the hybrid cells (hybridomas) that produced the desired antibody reactivity. These initial monoclonal products were mouse antibodies and were very valuable in laboratory and animal research and diagnostic assays, but were problematic as therapeutic agents because of immune reactions to the foreign mouse protein. Subsequently, production of chimeric mouse-human monoclonal antibodies and means of further “humanizing” them and producing fully human recombinant monoclonal antibodies were developed.
Chapter-1 Introduction to Human Anatomy and Physiology
Anatomy (Greek anatomē, 'dissection') is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science which deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic sciences that are applied in medicine.
National Health Programs, Objectives, Fucntions
Program among these measures are the NATIONAL HEALTH PROGRAMS, which have been launched by the central government of control/ eradication of communicable diseases, improvement of environmental sanitation, raising the standard of nutrition, control of population and improving rural health. Introduction
EU(European Union) and ICH Guidelines
The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) is unique in bringing together the regulatory authorities and pharmaceutical industry to discuss scientific and technical aspects of drug registration. Since its inception in 1990, ICH has gradually evolved, to respond to the increasingly global face of drug development. ICH’s mission is to achieve greater harmonisation worldwide to ensure that safe, effective, and high quality medicines are developed and registered in the most resource-efficient manner. On 23 October 2015, ICH announced organisational changes as it marks 25 years of successful harmonisation.
Forms of business organization, DSBM D.Pharma 2nd year
The legal entity can be in any form of a business organization. The various forms of organization are as follows: 1) Sole proprietorship 2) Partnership 3) Co-operative Society 4) Joint stock company (Private and Public) These are explained in brief as follows:-3.1 OBJECTIVES At the end of this lesson you will be able to know z Various forms of organization z Its formation & features z Merits & Demerits
Recommended
Questions of Central Nervous System
The document provides 6 multiple choice questions about the nervous system: 1) The structure and functions of neurons, 2) The various lobes of the brain and their functions, 3) What the meninges are, 4) A note on the ventricles, 5) What CSF is and its functions, 6) What reflex action is and the parts of the reflex arc. Students are instructed to attempt any 5 questions worth 5 marks each.
Drug Store and Business Management (DSBM).pdf
Human life is based upon the principle of work.
▪ One has to work to earn his livelihood.
▪ Pharmacy is one of the professions.
▪ The pharmacy council of India has introduced a new subject
named “Drug store and business management”.
▪ Syllabus is divided into two parts – part I commerce and part
II Accountancy.
▪ The purpose of this subject is to familiarise the students with
the basic concept of business, its proper management, sources
of finances in order to run it successfully and the last, the way
and means to note down various transactions in books of
account with a view to having a permanent record of the same.
Channels of Distribution.pdf
Distribution is significant rated as a significant function of marketing. After
production a product moves to the market and finally to the consumer.
▪ This journey of the product from the manufacturer or producer to the consumer is
made possible through certain defined paths, termed as, “Channels of
Distribution”
Monoclonal Antibody Process.pdf
Monoclonal antibodies are antibodies that have a high degree of specificity (mono-specificity) for an antigen or epitope. Monoclonal antibodies are typically derived from a clonal expansion of antibody producing malignant human plasma cells. The initial monoclonal antibodies were created by fusing spleen cells from an immunized mouse with human or mouse myeloma cells (malignant self-perpetuating antibody producing cells), and selecting out and cloning the hybrid cells (hybridomas) that produced the desired antibody reactivity. These initial monoclonal products were mouse antibodies and were very valuable in laboratory and animal research and diagnostic assays, but were problematic as therapeutic agents because of immune reactions to the foreign mouse protein. Subsequently, production of chimeric mouse-human monoclonal antibodies and means of further “humanizing” them and producing fully human recombinant monoclonal antibodies were developed.
Chapter-1 Introduction to Human Anatomy and Physiology
Anatomy (Greek anatomē, 'dissection') is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science which deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic sciences that are applied in medicine.
National Health Programs, Objectives, Fucntions
Program among these measures are the NATIONAL HEALTH PROGRAMS, which have been launched by the central government of control/ eradication of communicable diseases, improvement of environmental sanitation, raising the standard of nutrition, control of population and improving rural health. Introduction
EU(European Union) and ICH Guidelines
The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) is unique in bringing together the regulatory authorities and pharmaceutical industry to discuss scientific and technical aspects of drug registration. Since its inception in 1990, ICH has gradually evolved, to respond to the increasingly global face of drug development. ICH’s mission is to achieve greater harmonisation worldwide to ensure that safe, effective, and high quality medicines are developed and registered in the most resource-efficient manner. On 23 October 2015, ICH announced organisational changes as it marks 25 years of successful harmonisation.
Forms of business organization, DSBM D.Pharma 2nd year
The legal entity can be in any form of a business organization. The various forms of organization are as follows: 1) Sole proprietorship 2) Partnership 3) Co-operative Society 4) Joint stock company (Private and Public) These are explained in brief as follows:-3.1 OBJECTIVES At the end of this lesson you will be able to know z Various forms of organization z Its formation & features z Merits & Demerits
Psoriasis: Natural Product and Phytomedicine
Psoriasis is an autoimmune condition that affects skin. It is characterized by changes in the skin that include hyperkeratosis, parakeratosis, and akantosis.
They are attributed to an increased mitosis rate in the basal region of the epidermis, as well as disorders of maturing and differentiating keratinocytes.
These changes in the dermis and epidermis cause the typical desquamation of the stratum corneum observed in psoriasis. The psoriatic lesions indicate an inflammatory reaction caused by the secretion of pro-inflammatory cytokines from macrophages, lymphocytes, and neutrophils.
These cytokines may stimulate the inflammatory response via the lipoxygenase and the cyclooxygenase (COX) pathways.
The red, scaling psoriatic plaques often itch and burn. People with psoriasis may suffer discomfort, including pain and itching and emotional distress Psoriasis affects 1% to 2% of the population.
Omega 3 fatty acids d rc
Omega−3 fatty acids, also called Omega-3
oils, ω−3 fatty acids or n−3 fatty acids,
are polyunsaturated fatty acids (PUFAs)
characterized by the presence of a double
bond three atoms away from the terminal
methyl group in their chemical structure.
They are widely distributed in nature, being
important constituents of animal lipid
metabolism, and they play an important
role in the human diet and in human
physiology.
https://www.slideshare.net/DauRamChandravanshi1
Pilot Plant Techniques for SOLID dosage forms
Pilot Plant:-
“Defined as a part of pharmaceutical industry where a lab scale formula is transformed into viable product by the development of liable practical procedure for manufacture”.
Scale-up:-
“The art of designing of prototype using the data obtained from the pilot plant model”
Optimum Performance Laminar Chromatography (OPLC)
Optimum performance laminar chromatography (OPLC) is a pumped flow chromatography techniques that combine the user – friendly interface of HPLC with the capacity of flash chromatography and multidimensionally of TLC .
Optimum performance laminar chromatography (OPLC ) , in a contrast , is a pumped flow chromatography system that uses a planar 2D column format .
The multidimensionally capacity of OPLC is not limited to the separation technique alone , but also to the multitude of sample application and detection methods that are available .
SYNTHETIC PEPTIDE VACCINES AND RECOMBINANT ANTIGEN VACCINE
This document discusses synthetic peptide vaccines and recombinant antigen vaccines. It begins with definitions of vaccines and how they work to induce an immune response. It then describes two types of modern vaccines: synthetic peptide vaccines and recombinant antigen vaccines. Synthetic peptide vaccines use short fragments of viral or bacterial proteins that contain epitopes to induce an immune response, while recombinant antigen vaccines produce antigens through DNA technology by inserting viral or bacterial DNA into cells that then express the antigen protein. Both types of modern vaccines offer advantages over traditional vaccines like easier production and stability without refrigeration.
New generation vaccines production
vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future.
HISTORY OF VACCINES-
EDWARD JENNER conduct experiments in 1796 that lead to the creation of the first smallpox vaccine for prevention of smallpox.
A vaccine for RABIES is developed by LOUIS PASTEUR .
Vaccine for COLERA and TYPHOID were developed in 1896 and PLAGE vaccine in 1887.
The first DIPHTHERIA vaccine is developed in about 1913 by EMIL ADOLPH BEHRING,WILLIAM HALLOCK PARK.
The whole cell PERTUSIS vaccines are developed in 1914.
A TETANUS vaccine is developed in 1927.
Monoclonal Antibody and Hybridoma technology
Immunity
It can be defined as the resistance to disease, specifically to infectious disease or pathogens. The term “immune” is derived from the Latin word “immunis” that is exempt from charges. In medical term, it refers to the being protected from infectious pathogens.
Immune system
It is adaptive defense system which is able to generate a variety of cell and molecules capable of specifically recognizing and eliminating a variety of limitless foreign invaders into the system.
In 1975 Georges Kohler and Milstein succeeded in making fusions of myeloma cell lines with B cells to create hybridomas that could produce antibodies.
antibody
Also known as immunoglobulin is a large, Y shaped glycoprotein produced mainly by plasma cells that is used by the immune system to neutralize pathogens.
monoclonal antibodies
Antibodies that are made by identical immune cells that are clones of a unique parent cell.
polyclonal antibodies
A polyclonal antibodies represents a collection of antibodies from different B cells that recognize multiple epitopes on the same antigen.
Scanning Electron Microscope (SEM)
A scanning electron microscope is a type of electron microscope that produces images of a sample by scanning the surface with a focused beam of electrons. The electrons interact with atoms in the sample, producing various signals that contain information about the sample's surface topography and composition.
SEMs can magnify an object from about 10 times up to 300,000 times. A scale bar is often provided on an SEM image. From this the actual size of structures in the image can be calculated.
Gas chromatography mass spectrometry (GC-MS)
Gas chromatography-mass spectrometry (GC-MS) is the synergistic combination of two analytical method to separate and identify different substances within a test sample.
Gas chromatography separates the components of a mixture in time.
Mass spectrometer provides information that aids in the identification and structural elucidation of each component.
Formulation of parenteral products
These are the sterile preparation intended to administered other than intestinal route to bypass first pass metabolism and directly goes to systemic circulation.
These preparation give quick onset of action and site specific activity.
Suitable for drugs which are inactive in GIT environment.
Can be given unconscious or vomiting or diarrheal patient.
These are the sterile preparation intended to administered other than intestinal route to bypass first pass metabolism and directly goes to systemic circulation.
These preparation give quick onset of action and site specific activity.
Suitable for drugs which are inactive in GIT environment.
Can be given unconscious or vomiting or diarrheal patient.
Evaluation of parenterals products
Parenterals are the sterile preparation that is directly administered into the circulatory system avoiding the enteral route. And these preparation provide rapid onset of action that is why the administered preparation must be safe.
Stability problem arise from microbial contamination of these products so sterility and stability must be ensured for these preparations.
To ensure their sterility and stability, regulations regarding to quality control through pharmacopeial specifications has great importance.
Factors affecting Design of Experiment (DOE) and softwares of DOE
What is an experiment ?
An experiment refers to any process that generates a set of data.
An experiment involves a test or series of test in which purposeful changes are made to the input variables of a process or system so that changes in the output responses can be observed and identified.
Containers and closures for parenteral preparations
Containers are in intimate contact with the product. No container presently available is totally non reactive, particularly with aqueous solutions . Both the chemical and physical characteristics are given primary consideration in the selection of a protective container . Glass containers traditionally have been used for sterile products , many of which are closed with rubber stoppers. Interest in plastic containers for parenterals is increasing and such containers are being used for commercial ophthalmic preparations and IV solutions.
NMR- Diamagnetic Anisotropy and its effect on chemical shift
The shift in the position of the NMR region resulting from the shielding and deshielding by electrons is called chemical shift.
When a proton is present inside the magnetic field more close to an electro positive atom more applied magnetic field is required to cause excitation. This effect is called shielding effect.
When a proton is present outside the magnetic field close to a electronegative atom less applied magnetic field is required to cause excitation . This effect is called deshielding effect
Optimization techniques in formulation Development- Plackett Burmann Design a...
It is the process of finding the best way of using the existing resources while taking in to the account of all the factors that influences decisions in any experiment.
The objective of designing quality formulation is achieved by various optimization techniques.
In Pharmacy word “optimization” is found in the literature referring to study of the formula. In formulation development process generally experiments by a series of logical steps, carefully controlling the variables and changing one at a time until satisfactory results are obtained.
Gene therapy of genetic disorders like hepatitis, neuroblastoma, thalassemia
Gene therapy is the modern techniques of treatment of various diseases and disorders.
Gene therapy is the introduction of genes into existing cells to prevent or cure a wide range of diseases.
It is a technique for correcting defective genes responsible for disease development.
Inactivating, or “knocking out,” a mutated gene that is functioning improperly.
The first approved gene therapy experiment occurred on September1990 in US, when Ashanti DeSilva was treated for ADA-SCID.
Under the direction of William French Anderson, at the National Institutes of Health (NIH),
Coupling vibration in IR(Infra Red) spectroscopy and their significance.
Introduction, Coupling vibration, Requirements for effective coupling, References.
coupling occurs in IR by stretching and bending vibration, symmetrical and asymmetrical stretching vibration.
Optimization techniques in formulation Development Response surface methodol...
The term “optimize” is “to make as perfect”. It is defined as follows: choosing the best element from some set of variable alternatives.
An art ,process ,or methodology of making something (a design system or decision ) as perfect ,as functional, as effective as possible .
Infrared spectroscopy IR
This document provides an overview of infrared spectroscopy. It discusses how infrared radiation interacts with molecules by causing vibrations between their atomic bonds. The absorption of infrared radiation depends on characteristics like the mass of the atoms in the bond and the stiffness of the chemical bond. Quantum mechanics describes the vibrational energy levels of molecules as discrete, quantized values. Even at absolute zero, molecules will possess a minimum vibrational energy called zero-point energy due to their quantum nature. Infrared spectroscopy can reveal information about molecular structure by examining their characteristic vibrational frequencies.
Pilot plant Techniques and Product consideration for liquid dosage forms.
CONTENTS:-
DEFINITION
INTRODUCTION
OBJECTIVES
LIQUID DOSAGE FORM
STEPS INVOLVED IN PILOT PLANT FOR ORAL LIQUID
GENERAL CONSIDERATION
Reporting responsibility
Personal requirements
Space requirements
Review of formula
Raw materials
Relevant processing equipments
Process evaluation
GMP consideration
Assurance
PILOT PLANT SCALE UP FOR SUSPENSION
PILOT PLANT SCALE UP FOR EMULSION
REFERENCES
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...Nguyen Thanh Tu Collection
https://app.box.com/s/tacvl9ekroe9hqupdnjruiypvm9rdaneMore Related Content
More from D.R. Chandravanshi
Psoriasis: Natural Product and Phytomedicine
Psoriasis is an autoimmune condition that affects skin. It is characterized by changes in the skin that include hyperkeratosis, parakeratosis, and akantosis.
They are attributed to an increased mitosis rate in the basal region of the epidermis, as well as disorders of maturing and differentiating keratinocytes.
These changes in the dermis and epidermis cause the typical desquamation of the stratum corneum observed in psoriasis. The psoriatic lesions indicate an inflammatory reaction caused by the secretion of pro-inflammatory cytokines from macrophages, lymphocytes, and neutrophils.
These cytokines may stimulate the inflammatory response via the lipoxygenase and the cyclooxygenase (COX) pathways.
The red, scaling psoriatic plaques often itch and burn. People with psoriasis may suffer discomfort, including pain and itching and emotional distress Psoriasis affects 1% to 2% of the population.
Omega 3 fatty acids d rc
Omega−3 fatty acids, also called Omega-3
oils, ω−3 fatty acids or n−3 fatty acids,
are polyunsaturated fatty acids (PUFAs)
characterized by the presence of a double
bond three atoms away from the terminal
methyl group in their chemical structure.
They are widely distributed in nature, being
important constituents of animal lipid
metabolism, and they play an important
role in the human diet and in human
physiology.
https://www.slideshare.net/DauRamChandravanshi1
Pilot Plant Techniques for SOLID dosage forms
Pilot Plant:-
“Defined as a part of pharmaceutical industry where a lab scale formula is transformed into viable product by the development of liable practical procedure for manufacture”.
Scale-up:-
“The art of designing of prototype using the data obtained from the pilot plant model”
Optimum Performance Laminar Chromatography (OPLC)
Optimum performance laminar chromatography (OPLC) is a pumped flow chromatography techniques that combine the user – friendly interface of HPLC with the capacity of flash chromatography and multidimensionally of TLC .
Optimum performance laminar chromatography (OPLC ) , in a contrast , is a pumped flow chromatography system that uses a planar 2D column format .
The multidimensionally capacity of OPLC is not limited to the separation technique alone , but also to the multitude of sample application and detection methods that are available .
SYNTHETIC PEPTIDE VACCINES AND RECOMBINANT ANTIGEN VACCINE
This document discusses synthetic peptide vaccines and recombinant antigen vaccines. It begins with definitions of vaccines and how they work to induce an immune response. It then describes two types of modern vaccines: synthetic peptide vaccines and recombinant antigen vaccines. Synthetic peptide vaccines use short fragments of viral or bacterial proteins that contain epitopes to induce an immune response, while recombinant antigen vaccines produce antigens through DNA technology by inserting viral or bacterial DNA into cells that then express the antigen protein. Both types of modern vaccines offer advantages over traditional vaccines like easier production and stability without refrigeration.
New generation vaccines production
vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future.
HISTORY OF VACCINES-
EDWARD JENNER conduct experiments in 1796 that lead to the creation of the first smallpox vaccine for prevention of smallpox.
A vaccine for RABIES is developed by LOUIS PASTEUR .
Vaccine for COLERA and TYPHOID were developed in 1896 and PLAGE vaccine in 1887.
The first DIPHTHERIA vaccine is developed in about 1913 by EMIL ADOLPH BEHRING,WILLIAM HALLOCK PARK.
The whole cell PERTUSIS vaccines are developed in 1914.
A TETANUS vaccine is developed in 1927.
Monoclonal Antibody and Hybridoma technology
Immunity
It can be defined as the resistance to disease, specifically to infectious disease or pathogens. The term “immune” is derived from the Latin word “immunis” that is exempt from charges. In medical term, it refers to the being protected from infectious pathogens.
Immune system
It is adaptive defense system which is able to generate a variety of cell and molecules capable of specifically recognizing and eliminating a variety of limitless foreign invaders into the system.
In 1975 Georges Kohler and Milstein succeeded in making fusions of myeloma cell lines with B cells to create hybridomas that could produce antibodies.
antibody
Also known as immunoglobulin is a large, Y shaped glycoprotein produced mainly by plasma cells that is used by the immune system to neutralize pathogens.
monoclonal antibodies
Antibodies that are made by identical immune cells that are clones of a unique parent cell.
polyclonal antibodies
A polyclonal antibodies represents a collection of antibodies from different B cells that recognize multiple epitopes on the same antigen.
Scanning Electron Microscope (SEM)
A scanning electron microscope is a type of electron microscope that produces images of a sample by scanning the surface with a focused beam of electrons. The electrons interact with atoms in the sample, producing various signals that contain information about the sample's surface topography and composition.
SEMs can magnify an object from about 10 times up to 300,000 times. A scale bar is often provided on an SEM image. From this the actual size of structures in the image can be calculated.
Gas chromatography mass spectrometry (GC-MS)
Gas chromatography-mass spectrometry (GC-MS) is the synergistic combination of two analytical method to separate and identify different substances within a test sample.
Gas chromatography separates the components of a mixture in time.
Mass spectrometer provides information that aids in the identification and structural elucidation of each component.
Formulation of parenteral products
These are the sterile preparation intended to administered other than intestinal route to bypass first pass metabolism and directly goes to systemic circulation.
These preparation give quick onset of action and site specific activity.
Suitable for drugs which are inactive in GIT environment.
Can be given unconscious or vomiting or diarrheal patient.
These are the sterile preparation intended to administered other than intestinal route to bypass first pass metabolism and directly goes to systemic circulation.
These preparation give quick onset of action and site specific activity.
Suitable for drugs which are inactive in GIT environment.
Can be given unconscious or vomiting or diarrheal patient.
Evaluation of parenterals products
Parenterals are the sterile preparation that is directly administered into the circulatory system avoiding the enteral route. And these preparation provide rapid onset of action that is why the administered preparation must be safe.
Stability problem arise from microbial contamination of these products so sterility and stability must be ensured for these preparations.
To ensure their sterility and stability, regulations regarding to quality control through pharmacopeial specifications has great importance.
Factors affecting Design of Experiment (DOE) and softwares of DOE
What is an experiment ?
An experiment refers to any process that generates a set of data.
An experiment involves a test or series of test in which purposeful changes are made to the input variables of a process or system so that changes in the output responses can be observed and identified.
Containers and closures for parenteral preparations
Containers are in intimate contact with the product. No container presently available is totally non reactive, particularly with aqueous solutions . Both the chemical and physical characteristics are given primary consideration in the selection of a protective container . Glass containers traditionally have been used for sterile products , many of which are closed with rubber stoppers. Interest in plastic containers for parenterals is increasing and such containers are being used for commercial ophthalmic preparations and IV solutions.
NMR- Diamagnetic Anisotropy and its effect on chemical shift
The shift in the position of the NMR region resulting from the shielding and deshielding by electrons is called chemical shift.
When a proton is present inside the magnetic field more close to an electro positive atom more applied magnetic field is required to cause excitation. This effect is called shielding effect.
When a proton is present outside the magnetic field close to a electronegative atom less applied magnetic field is required to cause excitation . This effect is called deshielding effect
Optimization techniques in formulation Development- Plackett Burmann Design a...
It is the process of finding the best way of using the existing resources while taking in to the account of all the factors that influences decisions in any experiment.
The objective of designing quality formulation is achieved by various optimization techniques.
In Pharmacy word “optimization” is found in the literature referring to study of the formula. In formulation development process generally experiments by a series of logical steps, carefully controlling the variables and changing one at a time until satisfactory results are obtained.
Gene therapy of genetic disorders like hepatitis, neuroblastoma, thalassemia
Gene therapy is the modern techniques of treatment of various diseases and disorders.
Gene therapy is the introduction of genes into existing cells to prevent or cure a wide range of diseases.
It is a technique for correcting defective genes responsible for disease development.
Inactivating, or “knocking out,” a mutated gene that is functioning improperly.
The first approved gene therapy experiment occurred on September1990 in US, when Ashanti DeSilva was treated for ADA-SCID.
Under the direction of William French Anderson, at the National Institutes of Health (NIH),
Coupling vibration in IR(Infra Red) spectroscopy and their significance.
Introduction, Coupling vibration, Requirements for effective coupling, References.
coupling occurs in IR by stretching and bending vibration, symmetrical and asymmetrical stretching vibration.
Optimization techniques in formulation Development Response surface methodol...
The term “optimize” is “to make as perfect”. It is defined as follows: choosing the best element from some set of variable alternatives.
An art ,process ,or methodology of making something (a design system or decision ) as perfect ,as functional, as effective as possible .
Infrared spectroscopy IR
This document provides an overview of infrared spectroscopy. It discusses how infrared radiation interacts with molecules by causing vibrations between their atomic bonds. The absorption of infrared radiation depends on characteristics like the mass of the atoms in the bond and the stiffness of the chemical bond. Quantum mechanics describes the vibrational energy levels of molecules as discrete, quantized values. Even at absolute zero, molecules will possess a minimum vibrational energy called zero-point energy due to their quantum nature. Infrared spectroscopy can reveal information about molecular structure by examining their characteristic vibrational frequencies.
Pilot plant Techniques and Product consideration for liquid dosage forms.
CONTENTS:-
DEFINITION
INTRODUCTION
OBJECTIVES
LIQUID DOSAGE FORM
STEPS INVOLVED IN PILOT PLANT FOR ORAL LIQUID
GENERAL CONSIDERATION
Reporting responsibility
Personal requirements
Space requirements
Review of formula
Raw materials
Relevant processing equipments
Process evaluation
GMP consideration
Assurance
PILOT PLANT SCALE UP FOR SUSPENSION
PILOT PLANT SCALE UP FOR EMULSION
REFERENCES
More from D.R. Chandravanshi (20)
SYNTHETIC PEPTIDE VACCINES AND RECOMBINANT ANTIGEN VACCINE
SYNTHETIC PEPTIDE VACCINES AND RECOMBINANT ANTIGEN VACCINE
Factors affecting Design of Experiment (DOE) and softwares of DOE
Factors affecting Design of Experiment (DOE) and softwares of DOE
Containers and closures for parenteral preparations
Containers and closures for parenteral preparations
NMR- Diamagnetic Anisotropy and its effect on chemical shift
NMR- Diamagnetic Anisotropy and its effect on chemical shift
Optimization techniques in formulation Development- Plackett Burmann Design a...
Optimization techniques in formulation Development- Plackett Burmann Design a...
Gene therapy of genetic disorders like hepatitis, neuroblastoma, thalassemia
Gene therapy of genetic disorders like hepatitis, neuroblastoma, thalassemia
Coupling vibration in IR(Infra Red) spectroscopy and their significance.
Coupling vibration in IR(Infra Red) spectroscopy and their significance.
Optimization techniques in formulation Development Response surface methodol...
Optimization techniques in formulation Development Response surface methodol...
Pilot plant Techniques and Product consideration for liquid dosage forms.
Pilot plant Techniques and Product consideration for liquid dosage forms.
Recently uploaded
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...Nguyen Thanh Tu Collection
https://app.box.com/s/tacvl9ekroe9hqupdnjruiypvm9rdaneJemison, MacLaughlin, and Majumder "Broadening Pathways for Editors and Authors"
Jemison, MacLaughlin, and Majumder "Broadening Pathways for Editors and Authors"National Information Standards Organization (NISO)
This presentation was provided by Racquel Jemison, Ph.D., Christina MacLaughlin, Ph.D., and Paulomi Majumder. Ph.D., all of the American Chemical Society, for the second session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session Two: 'Expanding Pathways to Publishing Careers,' was held June 13, 2024.Gender and Mental Health - Counselling and Family Therapy Applications and In...
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
HYPERTENSION - SLIDE SHARE PRESENTATION.
IT WILL BE HELPFULL FOR THE NUSING STUDENTS
IT FOCUSED ON MEDICAL MANAGEMENT AND NURSING MANAGEMENT.
HIGHLIGHTS ON HEALTH EDUCATION.
Benner "Expanding Pathways to Publishing Careers"
This presentation was provided by Rebecca Benner, Ph.D., of the American Society of Anesthesiologists, for the second session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session Two: 'Expanding Pathways to Publishing Careers,' was held June 13, 2024.
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.ppt
The History of NZ 1870-1900.
Making of a Nation.
From the NZ Wars to Liberals,
Richard Seddon, George Grey,
Social Laboratory, New Zealand,
Confiscations, Kotahitanga, Kingitanga, Parliament, Suffrage, Repudiation, Economic Change, Agriculture, Gold Mining, Timber, Flax, Sheep, Dairying,
BIOLOGY NATIONAL EXAMINATION COUNCIL (NECO) 2024 PRACTICAL MANUAL.pptx
Practical manual for National Examination Council, Nigeria.
Contains guides on answering questions on the specimens provided
How to Setup Warehouse & Location in Odoo 17 Inventory
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Wound healing PPT
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
This Dissertation explores the particular circumstances of Mirzapur, a region located in the
core of India. Mirzapur, with its varied terrains and abundant biodiversity, offers an optimal
environment for investigating the changes in vegetation cover dynamics. Our study utilizes
advanced technologies such as GIS (Geographic Information Systems) and Remote sensing to
analyze the transformations that have taken place over the course of a decade.
The complex relationship between human activities and the environment has been the focus
of extensive research and worry. As the global community grapples with swift urbanization,
population expansion, and economic progress, the effects on natural ecosystems are becoming
more evident. A crucial element of this impact is the alteration of vegetation cover, which plays a
significant role in maintaining the ecological equilibrium of our planet.Land serves as the foundation for all human activities and provides the necessary materials for
these activities. As the most crucial natural resource, its utilization by humans results in different
'Land uses,' which are determined by both human activities and the physical characteristics of the
land.
The utilization of land is impacted by human needs and environmental factors. In countries
like India, rapid population growth and the emphasis on extensive resource exploitation can lead
to significant land degradation, adversely affecting the region's land cover.
Therefore, human intervention has significantly influenced land use patterns over many
centuries, evolving its structure over time and space. In the present era, these changes have
accelerated due to factors such as agriculture and urbanization. Information regarding land use and
cover is essential for various planning and management tasks related to the Earth's surface,
providing crucial environmental data for scientific, resource management, policy purposes, and
diverse human activities.
Accurate understanding of land use and cover is imperative for the development planning
of any area. Consequently, a wide range of professionals, including earth system scientists, land
and water managers, and urban planners, are interested in obtaining data on land use and cover
changes, conversion trends, and other related patterns. The spatial dimensions of land use and
cover support policymakers and scientists in making well-informed decisions, as alterations in
these patterns indicate shifts in economic and social conditions. Monitoring such changes with the
help of Advanced technologies like Remote Sensing and Geographic Information Systems is
crucial for coordinated efforts across different administrative levels. Advanced technologies like
Remote Sensing and Geographic Information Systems
9
Changes in vegetation cover refer to variations in the distribution, composition, and overall
structure of plant communities across different temporal and spatial scales. These changes can
occur natural.
Leveraging Generative AI to Drive Nonprofit Innovation
In this webinar, participants learned how to utilize Generative AI to streamline operations and elevate member engagement. Amazon Web Service experts provided a customer specific use cases and dived into low/no-code tools that are quick and easy to deploy through Amazon Web Service (AWS.)
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Aberdeen
Recently uploaded (20)
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
Jemison, MacLaughlin, and Majumder "Broadening Pathways for Editors and Authors"
Jemison, MacLaughlin, and Majumder "Broadening Pathways for Editors and Authors"
Gender and Mental Health - Counselling and Family Therapy Applications and In...
Gender and Mental Health - Counselling and Family Therapy Applications and In...
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.ppt
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.ppt
B. Ed Syllabus for babasaheb ambedkar education university.pdf
B. Ed Syllabus for babasaheb ambedkar education university.pdf
BIOLOGY NATIONAL EXAMINATION COUNCIL (NECO) 2024 PRACTICAL MANUAL.pptx
BIOLOGY NATIONAL EXAMINATION COUNCIL (NECO) 2024 PRACTICAL MANUAL.pptx
How to Setup Warehouse & Location in Odoo 17 Inventory
How to Setup Warehouse & Location in Odoo 17 Inventory
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptx
SWOT analysis in the project Keeping the Memory @live.pptx
SWOT analysis in the project Keeping the Memory @live.pptx
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
Leveraging Generative AI to Drive Nonprofit Innovation
Leveraging Generative AI to Drive Nonprofit Innovation
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
Channel of Distribution.pdf
- 1. D. R. Chandravanshi Asst. Professor (Ad hoc) Department of Pharmacy, Guru GhasidasVishwavidyalaya Bilaspur C.G.