A 58-year-old male was admitted with symptoms of vomiting, abdominal pain, and no stool passage, leading to a diagnosis of perforated duodenal ulcer. He underwent laparotomy surgery on 25/10/19 and was treated with antibiotics, vitamins, and supportive care. Post-surgery, the patient was advised on dietary modifications and lifestyle changes to improve his health and avoid complications.

1. A CASE PRESENTATION ON PERFORATED
DUODENAL ULCER
Presented by:
K. Sai Gowtham
17P91T0009
III rd Pharm D

2. CASE DETAILS:
 A 58 years old male patient bearing ip no:
69264 was admitted in the department of
General medicine (surgery) on 25/10/19 and
got discharged on 1/11/19 and the length of
stay of patient in hospital is 8 days.

3. Complaints of;
 Vomiting's since 2days
 Abdominal pain since 2days
 No passage of stools and flatus since 2days

4. Past medical history;
 Not a known case of hypertension and diabetes mellitus.
 No history of the fever.
Personal history;
 Diet – mixed
 No sleep disturbances
 Bowel and bladder habits normal

5. Social history;
 Known a chronic smoker and alcoholic and the last intake
is 4days back.
Surgical history;
 No past surgical history.

6. The physical exam on admission revealed the following findings:
 Patient - conscious and coherent
 Temperature – afebrile
 Pulse rate – 94bpm
 Respiratory rate – BLAE +
 Blood pressure – 110/70 mmHg
 Per abdomen – tenderness and rigidity is present

7. Vitals chart:
VITALS Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7
BP(
mmHg)
130/80 140/70 150/80 135/90 120/80 150/90 138/70
PR(bpm) 86 75 79 80 84 80 84
CVS S1 S2+ S1 S2 + S1 S2 + S1 S2 + S1 S2 + S1 S2 + S1 S2 +
RS BLAE + BLAE + BLAE + BLAE + BLAE + BLAE + BLAE +
TEMP A febrile 98.4 F 95.0 F 98.0 F A febrile A febrile A febrile
P/A Tender normal normal normal normal normal normal

8. Laboratory Investigations;
SN
O
Parameter Observed value Normal value
1 Haemoglobin 15.0g/dl 13 – 16 g/dl
2 RBC 5millcells/cub mm 4.5 -5.5 mill cells /cub mm
3 Sr. creatinine 1.33 mg/dl 0.3 – 1.30 mg/dl
4 Sr. potassium 3.0 mmol/L 3.50 – 5.00 mmol/L
5 Sr. urea 47 mg/dl 10.00 – 40.00 mg/dl
6 Sr. sodium 139 mmol/L 135.00 – 145.00 mmol/L
7 Sr. total protein 5.7g/dl 6.00 – 8.00 g/dl
8 Sr. albumin 3.0g/dl 3.00 – 5.50 g/dl

9. Other investigations;
 USG abdomen- Modern hepatic with ileum.
 X-ray abdomen – suspected some abnormality in the left side of abdomen.
 Chest X-ray - normal

10. On diagnosis;
Perforated duodenal ulcer.

11. Contd;
 Due to perforated ulcer surgery was performed to the
patient.
 Date of surgery : 25/10/19
 Method of surgery : laparotomy method

12. Surgical findings;
 0.5× 1 cm perforation present at the D1 of the duodenal area
and modified “Grahams patch” is kept at the site of
perforation.

13. Medication chart:
Sno. Name of the
drugs
Dose Route of
administration
Frequency Days of
treatment
1 2 3 4 5
1 Tab.
Augmentin
625 mg oral B.D
+ + + - -
2 Tab. Vit-C 135 mg Oral O.D + + + + -
3 Cap. Omez 20 mg Oral O.D + + + - -
4 Cap. becozinc Oral O.D + + + + +
5 Syrup.
sucralfate
10ml oral T.I.D + + + + -
6 Pylori.H kit S O S

15. SUBJECTIVE:
 Vomiting's since 2days.
 Abdomen pain since 2days.
 No passage of stools and flatus since 2days.
Theoretical Symptoms:
 Pain in upper chest and abdomen region.
 Belching
 Loss of appetite
 Indigestion

16. OBJECTIVE:
 Serum creatinine : 1.33mg/dl
 Total protein : 5.7 g/dl
 Serum urea : 47mg/dl
 Serum potassium : 3.0 mmol/L

17. ASSESMENT:
The main cause of this damage is infection with bacteria called Helicobacter pylori,
or H. pylori. The bacteria can cause the lining of your duodenum to become inflamed
and an ulcer can form.
Some medications can also cause a duodenal ulcer, particularly anti-inflammatory
drugs such as ibuprofen and aspirin. Rarely, other medicines or medical conditions might
cause an ulcer.
Symptoms of a duodenal ulcer:
If you have a duodenal ulcer, you might:
• Have pain in the stomach or abdomen (this might come and go)
• Indigestion.
• Feel very full and bloated after eating.
• Feel sick.
• Lose weight.

18. PLAN:
 As the patient had high level of serum creatinine to lower it
better avoid the protein food.
 To maintain sodium level take more salads, slatted nuts,
pickles, canned foods and sauces.
 Better to undergo the kidney function test.

19. PATIENT COUNSELLING:
 Avoid alcohol intake and quit smoking.
 Taking more spice foods and heavy meal like stuffed foods , biryanis
etc.,
 Do walking after having meal at night don’t go to bed immediately
after having meal.
 While sleeping the sleeping position should be in the inclined position
where head should be in the height region and legs in a lower region.
 Caffeine beverages should be avoided.
 Usage of the anti inflammatory drugs like aspirin, ibuprofen and
others should be decreased.
 More fiber rich food and leafy vegetables should be taken in diet.