Dear all,
This ppt contains the cause, clinical and radiological features, treatment and complication of fracture of the clavicle. I hope this is useful to you.
Thank you
Cervical spine clearance lecture given to 1st-year emergency medicine residents at Duke University. Covers indications for applying cervical collar, types of collars, types of imaging of the spine, and when to remove the collar.
Dear all,
This ppt contains the cause, clinical and radiological features, treatment and complication of fracture of the clavicle. I hope this is useful to you.
Thank you
Cervical spine clearance lecture given to 1st-year emergency medicine residents at Duke University. Covers indications for applying cervical collar, types of collars, types of imaging of the spine, and when to remove the collar.
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of fracture of lateral condyle of the humerus, medial epicondyle of Humerus, and intercondylar fracture of Humerus. I hope this is useful to you.
Thank you
In this article, we present how to treat posterior malleolar fractures , especially associated with syndesmosis injury by a case sharing. We also review the current concepts of posterior mallleolar fracture in ankle fracture by preoperative CT evaluation and surgical approach with modified PM approach.
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...drashraf369
slide presentation of a very promising surgical technic for a very elusive condition called avascular necrosis of femoral head.good clinical and surgical demo by dr mohamed ashraf,HOD, govt TD medical college ,alleppey,kerala, india
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of fracture of lateral condyle of the humerus, medial epicondyle of Humerus, and intercondylar fracture of Humerus. I hope this is useful to you.
Thank you
In this article, we present how to treat posterior malleolar fractures , especially associated with syndesmosis injury by a case sharing. We also review the current concepts of posterior mallleolar fracture in ankle fracture by preoperative CT evaluation and surgical approach with modified PM approach.
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...drashraf369
slide presentation of a very promising surgical technic for a very elusive condition called avascular necrosis of femoral head.good clinical and surgical demo by dr mohamed ashraf,HOD, govt TD medical college ,alleppey,kerala, india
Proximal physeal and SOH Fractures in pediatrics can be managed conservatively irrespective of alignment and reduction as it has great remodeling potential
The younger the age more deformity is acceptable in femur fracture
Treatment Modalities in pediatric femur fracture depends on the age and fracture pattern
Proximal tibia fracture will develop valgus deformity irrespective of treatment so counselling is must
Soft tissue status in the shaft of tibia factor determines the outcome in tibia fracture
management priorities in high energy trauma
Define the terms of fracture, dislocation and Subluxation
Identify the clinical and radiological pictures of fractures
Classify the different types of fractures
general principles of fracture management
Principles of open fracture management
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2. Q7/a 7yr old boy with FDA
• What is the most likely
Dx?
• Extension type
supracondylar fracture
• Garland III
3. • Why children most prone to this type of injury
• Hyper active prone to injury
• Growth spurt of distal epiphysis as compared to
supracondylar area
4. • What additional radiography, if any do you wish to
order?
• Johns view,contralateral elbow
• Oblique view/internal or external
• to see the commination
5. What aspect of this child exam are concerning
• Distal neurovascular
• Perfusion
• Pin and median nerve
• Tense swelling
• Puckering
8. Q8/pelvis x ray of 12yr young
• What is the most likely
dx
• SCFE/SUFE
• Epiphysis with in the
hip but
• Posterior mostly
• Anterior
• Lateral/valgus relative
to neck
10. • Displacement/southwick
angle or femoral
epiphysis shaft angle and
compare the difference
from contralateral side of
hip
• Mild <30 deg
• Mod 30 -60 deg
• Sever>60 deg
• If both side involved
measure from normal
• AP..145DEG
• Frog leg lat 10 deg
11. What aspect of this pt history put
him at risk for this injury
• Male
• Adolescent
• Obesity
• Hyper active
• Left hip
• Family hx
• Endocrinopathy
• Metabolic disease
16. • What is the next step in the management of this
patient
• Start with pain management
• Immobilization or avoid wt bearing
• Use crunch and ttable even for x ray
• Avoid cross leg lateral x ray in unstable slip…induce pain
• AP and frog leg lat x ray
• Look for slip as well as open physis
• Admit bed rest
• Definitive treatment
17. • Goal
• Stabilization of slip and prevent further slippage
• Closer o physis
• Reduction of displacement
18. In Situ Pinning
• Single scre …stable
• Doubble screw or unstable for rotation
• Avoid subchondral placement
• 6.5- to 7.3-mm stainless steel or titanium
cannulated screw
• Closed or open reduction pinning or screw
• Open epiphysisdosis
• Deformity surgery ---osteotomy
19. prognosis
• Complications
• Osteonecrosis of femoral head (4-6%)
• may occur as the result of
• initial trauma
• increased risk with high grade slips (~45-50%)
• operative complication (4-6%)
• hardware placement in posteriosuperior femoral neck has the
greatest risk of disrupting the vascular supply
• Contralateral hip SCFE
• most common complication after unilateral surgical fixation
(20-80%)
• risk factors for contralateral slip include
• male, obesity, young age of initial slip, endocrine disorders
20. • Chondrolysis (0-2%) associated with
• unrecognized implant penetration of the articular surface (0-2%)
• spica cast immobilization
• decreased prevalence with modern fluoroscopy
• Residual proximal femoral deformity & limb length discrepancy
• increased α-angle associated with symptomatic impingement
caused by failure of proximal femur to remodel
• Treatment
• intertrochanteric osteotomy (Imhauser)
• produces flexion, internal rotation and valgus
• subtrochanteric osteotomy (Southwick's
• cuneiform osteotomy (controversial due to high rate of osteonecrosis
and arthritis)
21. • sip progression
• occurs in 1-2% of cases following single screw fixation
• Infection (0-2%)
• Chronic pain (5-10%)
• Degenerative arthritis
• Pin associated proximal femur fracture
• Labral tearing and degeneration
• seen with high anterior and medial 2nd screw in-situ
fixation
22. Q9
• An otherwise healthy 65-
year-old man reports thigh
pain of insidious onset. He
states that the pain is
increased with weight
bearing and also occurs at
night. He denies any
history of cancer.
Radiographs are shown
below. A bone scan shows
an isolated lesion. CT
scans of the chest and
abdominal are negative for
any other lesions.
23. Describe the x ray findings?
• Multiple lytic lesion with
sclerotic bone and
cortical distraction no
gross periosteal reaction
25. What is the most likely diagnosis?
Chondrosarcoma
Infection boride
Secondary metastasis
Fibrous dysplasia
Multiple myeloma
26. Describe the stepwise management
approach of this patient?
• CT and MRI
• Biopsy ,FNAC is not representative
• RX
• Wide excision +chemotherapy
27. Treatment -chondrosarcoma
• Operative
• intra-lesional curettage
• Indications
• Grade 1 lesions
• treatment of grade 1 lesions located in the pelvis or axial
skeleton is controversial
• many authors recommend wide excision of all
chondrosarcomas (even grade 1) if located in the pelvis
28. • wide surgical excision
• Indications
• grade 2 or 3 lesions
• some say grade 1 lesions in pelvis
• historically, there is no significant role for radiation or
chemotherapy in typical intramedullary chondrosarcoma
• wide surgical excision combined with multi-agent
chemotherapy
• Indications
• mesenchymal chondrosarcoma
• the role of chemotherapy in de-differentiated
chondrosarcoma is very controversial
In most patients the cause of SCFE is unknown, but mechanical, endocrine, and genetic factors are thought to play a role
Definitive treatment alternatives for the
management of SCFE include in situ internal fixation or
pinning; bone graft epiphysiodesis; primary osteotomy
through the apex or base of the femoral neck or intertrochanteric
area, with or without fixation of the epiphysis to
the femoral neck; and application of a spica cast. The choice
of treatment depends on the type of slip and its severity,
and individual preferences and prejudices.
Postoperative Management. We allow protected partial
weight bearing with crutches as soon as the patient is comfortable,
usually within 24 hours of surgery; patients with
unstable slips may be slower to walk. The patient uses
crutches for 6 weeks, during which time the pain should
resolve completely. Athletic activities are allowed after 3
months. The patient is monitored for the development of
complications or contralateral slip by clinical examination
and radiography every 3 to 6 months until skeletal
maturity.
Presentation
Symptoms
o pain is the most common symptom
o may present with slowly growing mass or symptoms of bowel/bladder obstruction due to mass
effect in the pelvis
o 50% of de-differentiated chondrosarcomas present with a pathologic fracture
Imaging
Radiographs
o lytic or blastic lesion with reactive thickening of the cortex
low-grade chondrosarcomas show
similar appearance to enchondromas with additional cortical thickening/expansion and
endosteal erosion
high-grade chondrosarcomas show cortical destruction and a soft tissue mass
o intra-lesional "popcorn" mineralization may be seen
described as rings, arcs, and stipples of mineralization
o de-differentiated chondrosarcomas radiographically show a lower grade chondroid lesion
with superimposed highly destructive area consistent with the high grade transformed
dedifferentiated chondrosarcoma
MRI or CT
o helpful to determine cortical destruction, marrow involvement, and the soft tissue involvement
Bone scan
o is usually very hot in all grades of chondrosarcoma