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Gashaye T.
Case discussion
Q 22
 These are
MRI
scans of
the
injured
knee of
an 18-
year-old
junior
football
player. He
heard
large pop
when he
tried to
change
direction.
MRI knee anatomy
Questions
 What does the MRI show?
 Sagittal and coronal intercondylar section of knee
MRI
 SIGNAL change over ACL…coronal view
otherwise PCL is not clearly seen .. no comment
 Sagittal view
 Signal change over MCL
 LCL not clear
 PCL…seems normal
Dx : ACL rupture +?MCL rupture
How would you treat this injury?
Option
1. Non operative management
 willing to make lifestyle changes and avoid the
activities that cause recurrent instability
 an aggressive rehabilitation program and
counseling about activity level
 Functional knee Brace does not decrease reinjure
risk
2. repair of the anterior cruciate ligament (either
isolated or with augmentation)
3. reconstruction with either autograft or allograft
tissues or synthetics
When would you perform
reconstruction?
 He is young active sport man need repair of ACL or
reconstruction
 Either immediate repair or wait for MCL healing at
least two weeks
 Immediate repair
 mid substance tear high failure rate
 Recommended for avulsion injury
 Reconstruction
 Arthroscopic
 miniarthrotomy
 Resolution of inflammation around the knee and
return of full motion reduce the incidence of
postoperative knee stiffness
What are the graft choices for ACL
reconstruction?
 Auto graft
 low risk of adverse inflammatory reaction and virtually no
risk of disease transmission.
 Allograft
 bone–patellar tendon–bone graft
 usually is an 8- to 11-mm-wide
 from the central third of the patellar tendon, with its
adjacent patella and tibial bone blocks.
 high ultimate tensile load (approximately 2300 N),
 stiffness (approximately 620 N/mm)
 rigid fixation with its attached bony ends
Cont.
 quadrupled hamstring tendon graft
 semitendinosus or gracilis tendon
 ultimate tensile load reported to be as high as 4108 N
 Healing problem
 Lack rigid fixation
 quadriceps tendon graft
 harvested with a portion of patellar bone or entirely as a
soft-tissue graft
 ultimate tensile load of this graft to be as high as 2352 N
 for revision anterior cruciate ligament surgeries and for
knees with multiple ligament injuries
What would be your choice and why?
 BBPT
 simple to develop
 Strong fixation
 Low failure rate 3.1% as compared to hamstring
4.1%
 Problem
 Anterior knee pain
 Pain during kneeling
 Frequency of additional surgery seemed to be
related to the fixation method and not the graft
type
What are the key steps in performing
an ACL reconstruction?
 Diagnosis
 Graft development
 Graft placement
 Notchplasty
 Tibia and femoral tunneling
 Graft tensioning
 Graft fixation
 What fixation would you use?
 Direct fixation devices include interference
screws, staples, washers, and cross pins
 Indirect fixation devices include polyester
tape/titanium button and suture-post.
program be, and when would you
allow him to return to playing
football?
 The knee is placed in a controlled motion brace
locked in full extension.
 Protected range-of-motion exercises are begun
immediately
 Return for self training about 4month
 return to team practices with criteria and
limitations from the physical therapist by 6th
month
 Return to contact sport 9 to 12month
Q23.
 These are serious of x
rays of a 26 year old
man who presented with
longstanding complaint
of multiple joint pain
predominantly affecting
his neck, hip, knee and
hand areas
symmetrically.
 He is getting shorter
and crippled.
Questions
 Describe the x ray findings in each region?
 AP pelvic x ray
 Diffuse Osteopenia
 Deformed head ,flattened with significant joint space
narrowing
 Periarticular erosion
 No protrusion acetabula seen
 Knee x ray
 Joint space narrowing
 Periarticular Osteopnia and some erosion
 No osteophyte seen
 Hand x ray
 Multiple joint involvement both IP joint with osteopnia and
destructed joint
 No gross subluxation or dislocation seen
What additional work up do you
order?
 CBC
 Normocytic anemia with
increase plat count
 ESR,CRP
 elevated
 OFT(LFT,RFT)
 Albumin low
 RF
 High sen with low specificity
 ANAs
 Anti-CCPs
 Similar sensitivity with RF
but high specificity 95%
 MRI—bone marrow
edema espcially in early
arthrities
 Show synovities and
erosion
 Ultrasound
 Show erosion
 Synovial fluid analysis
Cont.
 What is your diagnosis?
 Rheumatoid Arthritis
 Favor
 Poly articular involvement
 Symmetrical
 X ray finding
 Cervical spine involvement
 Against
 Male sex
 ?DIP joint involved
 Large joint involvement
 What are the possible DDXs?
 RA
 OA
 Lupus arthritis
 Gout & Pseudo-gout
 Psoriatic arthritis
 Reactive arthritis
What diagnostic criteria you know
about this pt’s case?
 American college of
Rheumatology criteria, 1987
 The presence of at least 4
out of7 is required to classify
as RA
 Early morning stiffness >1hr
 Arthritis affecting 3 or more
joint areas
 Hand joint arthritis
 Symmetrical arthritis
 Rheumatoid nodules
 Rheumatoid factor
 Bone erosions
symptoms need to be
present for at least 6 wks to
make the Dx
 2010 new criteria
established by American
college of Rheumatology
& Eurpoean League
Against Rheumatism
(ACR/EULAR) score of
>6  unequivocal RA dx
What will be the management
algorism to treat this patient?
 It has no cure!
 Goal of treatment
 Symptomatic
improvement
 Slow disease
progression
 Prevent deformity and
treat
 Maintain function
Cont.
Cont.
 Generally management of RA
 Multidiciplanary
 General/non pharmacology
 Pt education or counseling
 exercise, diet, massage, stress
reduction, physical therapy
 active participation of the patient and
family
 Medical
 nonsteroidal anti-inflammatory drugs
(NSAIDs)
 nonbiologic and biologic disease-
modifying antirheumatic drugs
(DMARDs),
 immunosuppressants, and
corticosteroids
 surgical
Nonbiologic DMARD
Hydroxychloroquine
Azathioprine (AZA)
SSZ
MTX
Leflunomide
Cyclosporine
Gold salts
D-penicillamine
Minocycline
Biologic
DMARDs
adalimumab,
certolizumab,
etanercept,
golimumab and
infliximab.
TNF-α and interleukin (IL)-1 as central
proinflammatory cytokines
biologic agents-block these cytokines or
their effects.
Cont.
1st line Low dose steroids
2nd line DMARDs
3rd line DMARDs + biologic
agents/TNF
antagonists
4th line DMARDs +
Biologic agents/ IL-
1 antagonists
Cont.
Cont.
 SURGERY
 Synovectomy
 Tenosynovectomy
 Tendon realignment
 Reconstructive
surgery or
arthroplasty
 Arthrodesis
 Indications
 Involvement of one or few
joints
 Hyperplastic, “wet”
rheumatoid synovitis
 Failure to respond to
adequate trial of
nonoperative treatment
 No radiographic evidence
of articular cartilage
destruction
 Contraindications
 Seronegative “dry”
synovitis
 Polyarticular involvement
 Acute inflammatory stage
 Systemic disease
What is the unique challenge of
doing arthroplasty in such a patient?
 High risk of wear and failure
 High infection rate
 High dislocation rate as compared OA
 WHY?
 Implant choice
 Medical profile
 rehabilitation
Q 24
 A 62-year-old lady who
underwent a total hip
replacement four weeks
ago presents to EOPD
following a fall with severe
pain and inability to
weight-bear.
 This is her radiograph
Questions
 Describe the
abnormal findings on
the radiograph.
 Right hip AP x ray
 With cemented
femoral stem
dislocated posteriorly
from acetabular cup
 Grossly osteopenia
 What further
information would you
like to obtain on
history?
 Detailed history about
fall down injury
 Why this was done
primarily
 Other injury
 Presence of fever
previous to fall down
Cont..
 What further investigations would you request, if
any?
 CDC,ESR,CRP
 What is the diagnosis?
 Posterior dislocation after THA
What are the causes for a dislocation
following a total hip replacement?
 Different etiology dislocation
 Trauma
 Laxity
 Repair of the capsule and short external rotator
 Intraoperative assessment of the tension by telescoping of the
femoral stem
 Implant malposition
 safe zone’ of acetabular component 40° of inclination and 15° ±10°anteversion
 Femur stem antetorsion 15° ± 5°
 Both cup and stem position
 Improper implant choice
 Small size head ..jumping distance small high rate of dislocation with low wear
effect
 Large size head …low dislocation risk
 Impingement
 Osteophytes on both the acetabular or femoral side, capsular tissue, or scar tissue
can cause a dislocation displacing the head to posterior or anterior
 Noncompliant to post op rehab
 Neuromuscular disorders with pathologically increased muscle tension such as
Parkinson’s disease, cerebral palsy, and epilepsy
What treatment would you offer her?
Why?
 Closed reduction is carried out as soon as
possible after diagnosis to avoid neurologic injury
 Optimally, general anesthesia and fluoroscopy
are required, and commonly, 2 surgeons are
required to safely perform reduction maneuver
 Open reduction
 closed reduction fails or re-dislocation
 dislocation with massive hematoma formation
and/or palsy of the femoral or sciatic nerve occurs,
open reduction is mandatory
Surgical treatment option of
dislocation THA
Reference
 Campbell's operative orthopedics
 Orthobullet
 Rockwood and Green’s Fractures in Adults 8e
 Musculoskeletal MRI, 2nd Edition Clyde A.
Helms...Saunders (2008)
 A systematic review of guidelines for managing
rheumatoid arthritis
 Rheumatoid arthritis in adults: management NICE
guideline 2018
 Dislocation after total hip arthroplasty A. Zahar &
A. Rastogi & D. Kendoff
 Thank you!

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8th case discussion

  • 2. Q 22  These are MRI scans of the injured knee of an 18- year-old junior football player. He heard large pop when he tried to change direction.
  • 4. Questions  What does the MRI show?  Sagittal and coronal intercondylar section of knee MRI  SIGNAL change over ACL…coronal view otherwise PCL is not clearly seen .. no comment  Sagittal view  Signal change over MCL  LCL not clear  PCL…seems normal Dx : ACL rupture +?MCL rupture
  • 5. How would you treat this injury? Option 1. Non operative management  willing to make lifestyle changes and avoid the activities that cause recurrent instability  an aggressive rehabilitation program and counseling about activity level  Functional knee Brace does not decrease reinjure risk 2. repair of the anterior cruciate ligament (either isolated or with augmentation) 3. reconstruction with either autograft or allograft tissues or synthetics
  • 6. When would you perform reconstruction?  He is young active sport man need repair of ACL or reconstruction  Either immediate repair or wait for MCL healing at least two weeks  Immediate repair  mid substance tear high failure rate  Recommended for avulsion injury  Reconstruction  Arthroscopic  miniarthrotomy  Resolution of inflammation around the knee and return of full motion reduce the incidence of postoperative knee stiffness
  • 7. What are the graft choices for ACL reconstruction?  Auto graft  low risk of adverse inflammatory reaction and virtually no risk of disease transmission.  Allograft  bone–patellar tendon–bone graft  usually is an 8- to 11-mm-wide  from the central third of the patellar tendon, with its adjacent patella and tibial bone blocks.  high ultimate tensile load (approximately 2300 N),  stiffness (approximately 620 N/mm)  rigid fixation with its attached bony ends
  • 8. Cont.  quadrupled hamstring tendon graft  semitendinosus or gracilis tendon  ultimate tensile load reported to be as high as 4108 N  Healing problem  Lack rigid fixation  quadriceps tendon graft  harvested with a portion of patellar bone or entirely as a soft-tissue graft  ultimate tensile load of this graft to be as high as 2352 N  for revision anterior cruciate ligament surgeries and for knees with multiple ligament injuries
  • 9. What would be your choice and why?  BBPT  simple to develop  Strong fixation  Low failure rate 3.1% as compared to hamstring 4.1%  Problem  Anterior knee pain  Pain during kneeling  Frequency of additional surgery seemed to be related to the fixation method and not the graft type
  • 10. What are the key steps in performing an ACL reconstruction?  Diagnosis  Graft development  Graft placement  Notchplasty  Tibia and femoral tunneling  Graft tensioning  Graft fixation
  • 11.  What fixation would you use?  Direct fixation devices include interference screws, staples, washers, and cross pins  Indirect fixation devices include polyester tape/titanium button and suture-post.
  • 12. program be, and when would you allow him to return to playing football?  The knee is placed in a controlled motion brace locked in full extension.  Protected range-of-motion exercises are begun immediately  Return for self training about 4month  return to team practices with criteria and limitations from the physical therapist by 6th month  Return to contact sport 9 to 12month
  • 13. Q23.  These are serious of x rays of a 26 year old man who presented with longstanding complaint of multiple joint pain predominantly affecting his neck, hip, knee and hand areas symmetrically.  He is getting shorter and crippled.
  • 14.
  • 15. Questions  Describe the x ray findings in each region?  AP pelvic x ray  Diffuse Osteopenia  Deformed head ,flattened with significant joint space narrowing  Periarticular erosion  No protrusion acetabula seen  Knee x ray  Joint space narrowing  Periarticular Osteopnia and some erosion  No osteophyte seen  Hand x ray  Multiple joint involvement both IP joint with osteopnia and destructed joint  No gross subluxation or dislocation seen
  • 16. What additional work up do you order?  CBC  Normocytic anemia with increase plat count  ESR,CRP  elevated  OFT(LFT,RFT)  Albumin low  RF  High sen with low specificity  ANAs  Anti-CCPs  Similar sensitivity with RF but high specificity 95%  MRI—bone marrow edema espcially in early arthrities  Show synovities and erosion  Ultrasound  Show erosion  Synovial fluid analysis
  • 17. Cont.  What is your diagnosis?  Rheumatoid Arthritis  Favor  Poly articular involvement  Symmetrical  X ray finding  Cervical spine involvement  Against  Male sex  ?DIP joint involved  Large joint involvement  What are the possible DDXs?  RA  OA  Lupus arthritis  Gout & Pseudo-gout  Psoriatic arthritis  Reactive arthritis
  • 18. What diagnostic criteria you know about this pt’s case?  American college of Rheumatology criteria, 1987  The presence of at least 4 out of7 is required to classify as RA  Early morning stiffness >1hr  Arthritis affecting 3 or more joint areas  Hand joint arthritis  Symmetrical arthritis  Rheumatoid nodules  Rheumatoid factor  Bone erosions symptoms need to be present for at least 6 wks to make the Dx  2010 new criteria established by American college of Rheumatology & Eurpoean League Against Rheumatism (ACR/EULAR) score of >6  unequivocal RA dx
  • 19. What will be the management algorism to treat this patient?  It has no cure!  Goal of treatment  Symptomatic improvement  Slow disease progression  Prevent deformity and treat  Maintain function
  • 20. Cont.
  • 21. Cont.  Generally management of RA  Multidiciplanary  General/non pharmacology  Pt education or counseling  exercise, diet, massage, stress reduction, physical therapy  active participation of the patient and family  Medical  nonsteroidal anti-inflammatory drugs (NSAIDs)  nonbiologic and biologic disease- modifying antirheumatic drugs (DMARDs),  immunosuppressants, and corticosteroids  surgical Nonbiologic DMARD Hydroxychloroquine Azathioprine (AZA) SSZ MTX Leflunomide Cyclosporine Gold salts D-penicillamine Minocycline Biologic DMARDs adalimumab, certolizumab, etanercept, golimumab and infliximab. TNF-α and interleukin (IL)-1 as central proinflammatory cytokines biologic agents-block these cytokines or their effects.
  • 22. Cont. 1st line Low dose steroids 2nd line DMARDs 3rd line DMARDs + biologic agents/TNF antagonists 4th line DMARDs + Biologic agents/ IL- 1 antagonists
  • 23. Cont.
  • 24.
  • 25. Cont.  SURGERY  Synovectomy  Tenosynovectomy  Tendon realignment  Reconstructive surgery or arthroplasty  Arthrodesis  Indications  Involvement of one or few joints  Hyperplastic, “wet” rheumatoid synovitis  Failure to respond to adequate trial of nonoperative treatment  No radiographic evidence of articular cartilage destruction  Contraindications  Seronegative “dry” synovitis  Polyarticular involvement  Acute inflammatory stage  Systemic disease
  • 26. What is the unique challenge of doing arthroplasty in such a patient?  High risk of wear and failure  High infection rate  High dislocation rate as compared OA  WHY?  Implant choice  Medical profile  rehabilitation
  • 27. Q 24  A 62-year-old lady who underwent a total hip replacement four weeks ago presents to EOPD following a fall with severe pain and inability to weight-bear.  This is her radiograph
  • 28. Questions  Describe the abnormal findings on the radiograph.  Right hip AP x ray  With cemented femoral stem dislocated posteriorly from acetabular cup  Grossly osteopenia  What further information would you like to obtain on history?  Detailed history about fall down injury  Why this was done primarily  Other injury  Presence of fever previous to fall down
  • 29. Cont..  What further investigations would you request, if any?  CDC,ESR,CRP  What is the diagnosis?  Posterior dislocation after THA
  • 30. What are the causes for a dislocation following a total hip replacement?  Different etiology dislocation  Trauma  Laxity  Repair of the capsule and short external rotator  Intraoperative assessment of the tension by telescoping of the femoral stem  Implant malposition  safe zone’ of acetabular component 40° of inclination and 15° ±10°anteversion  Femur stem antetorsion 15° ± 5°  Both cup and stem position  Improper implant choice  Small size head ..jumping distance small high rate of dislocation with low wear effect  Large size head …low dislocation risk  Impingement  Osteophytes on both the acetabular or femoral side, capsular tissue, or scar tissue can cause a dislocation displacing the head to posterior or anterior  Noncompliant to post op rehab  Neuromuscular disorders with pathologically increased muscle tension such as Parkinson’s disease, cerebral palsy, and epilepsy
  • 31. What treatment would you offer her? Why?  Closed reduction is carried out as soon as possible after diagnosis to avoid neurologic injury  Optimally, general anesthesia and fluoroscopy are required, and commonly, 2 surgeons are required to safely perform reduction maneuver  Open reduction  closed reduction fails or re-dislocation  dislocation with massive hematoma formation and/or palsy of the femoral or sciatic nerve occurs, open reduction is mandatory
  • 32. Surgical treatment option of dislocation THA
  • 33. Reference  Campbell's operative orthopedics  Orthobullet  Rockwood and Green’s Fractures in Adults 8e  Musculoskeletal MRI, 2nd Edition Clyde A. Helms...Saunders (2008)  A systematic review of guidelines for managing rheumatoid arthritis  Rheumatoid arthritis in adults: management NICE guideline 2018  Dislocation after total hip arthroplasty A. Zahar & A. Rastogi & D. Kendoff

Editor's Notes

  1. Sagital view Cornal view Acl rupture Pcl rupture mcl…normal Lcl rupture
  2. Three factors known at the time of the initial examination that correlated with the need for surgery: younger age, preinjury hours of sports participation, and amount of anterior instability as measured by the KT-1000 arthrometer.
  3. As a biologic graft, an autograft undergoes revascularization and recollagenization, but initially a 50% loss of graft strength occurs after implantation. Therefore, it is desirable to begin with a graft stronger than the tissue to be replaced.
  4. Soft-tissue grafts can be secured to bone with soft-tissue interference screws, screws and spiked washers, screws and fixation plates, or staples. Studies comparing sutures, staples, screws with spiked washers, and plates have shown that spiked washers and plates have the greatest holding power. Interwoven heavy suture through the soft-tissue graft can be tied to bony bridges or around screws or staples. The screw is seated, and care is taken not to twist the washer in the soft tissue. The spacing and peripheral location of the spikes on the washer allow microcirculation to the graft. The limbs of the graft are sutured to each other with interrupted nonabsorbable sutures.