CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
3. 1- Primary cardiac tumors:
• MYXOMAS : Most common adult primary tumors
• PAPILLARY FIBROELASTOMAS : Most
common tumor of the cardiac valve
• SARCOMAS : Most common primary malignant
neoplasms in the heart
75%
ARE BENiGN
4. 2- Secondary tumors (metastatic):
o Much more common than primary cardiac tumors
o Most commonly from lung, breast, hematological, melanoma
o Cardiac metastases can arise via:
Hematogenous dissemination of cancer cells (i.e. melanoma, lymphoma)
Direct extension via adjacent tissues (i.e. lung)
Propagation to the RA via SVC and IVC (e.g. from renal cancer)
Retrograde lymphatic seeding (i.e. breast carcinoma)
5. Myxoma:
● Myxomas are the most common primary cardiac
tumor.
● More than 75% of myxomas originate in the left
atrium.
● Macroscopically, atrial myxomas are often
pedunculated rounded masses and soft in texture.
6. SYMPTOMS AND SiGNS:
1. Obstructive Symptoms (similar to mitral stenosis):
- dyspnea with exertion followed by orthopnea, paroxysmal nocturnal
dyspnea, and pulmonary edema.
- On physical exam, "tumor plop" may be characteristically heard early in
diastole.
2. Thromboembolic Symptoms: Neurologic defects
3. Constitutional Symptoms: fever, malaise, anorexia,
arthralgia, weight loss
10. ● Complications: CHF, Arrhythmias, Valvular defects,
Thromboembolic Events and infection
● Treatment: Considering the risk of cardiovascular
complications and embolization, surgical excision is the
treatment of choice for atrial myxomas
11. CREDITS: This presentation template was created by Slidesgo, and
includes icons by Flaticon and infographics & images by Freepik
Do you have any questions?
Jane-nader@buc.edu.eg