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CARDIAC
TUMORS
JANE NADER ABOULENEIN, MD
TYPES
PRIMARY SECONDARY
1- Primary cardiac tumors:
• MYXOMAS : Most common adult primary tumors
• PAPILLARY FIBROELASTOMAS : Most
common tumor of the cardiac valve
• SARCOMAS : Most common primary malignant
neoplasms in the heart
75%
ARE BENiGN
2- Secondary tumors (metastatic):
o Much more common than primary cardiac tumors
o Most commonly from lung, breast, hematological, melanoma
o Cardiac metastases can arise via:
 Hematogenous dissemination of cancer cells (i.e. melanoma, lymphoma)
 Direct extension via adjacent tissues (i.e. lung)
 Propagation to the RA via SVC and IVC (e.g. from renal cancer)
 Retrograde lymphatic seeding (i.e. breast carcinoma)
Myxoma:
● Myxomas are the most common primary cardiac
tumor.
● More than 75% of myxomas originate in the left
atrium.
● Macroscopically, atrial myxomas are often
pedunculated rounded masses and soft in texture.
SYMPTOMS AND SiGNS:
1. Obstructive Symptoms (similar to mitral stenosis):
- dyspnea with exertion followed by orthopnea, paroxysmal nocturnal
dyspnea, and pulmonary edema.
- On physical exam, "tumor plop" may be characteristically heard early in
diastole.
2. Thromboembolic Symptoms: Neurologic defects
3. Constitutional Symptoms: fever, malaise, anorexia,
arthralgia, weight loss
IMAGING
ECHO
ECHO
● Complications: CHF, Arrhythmias, Valvular defects,
Thromboembolic Events and infection
● Treatment: Considering the risk of cardiovascular
complications and embolization, surgical excision is the
treatment of choice for atrial myxomas
CREDITS: This presentation template was created by Slidesgo, and
includes icons by Flaticon and infographics & images by Freepik
Do you have any questions?
Jane-nader@buc.edu.eg

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Cardiac Tumors for medical students Jane Nader

  • 3. 1- Primary cardiac tumors: • MYXOMAS : Most common adult primary tumors • PAPILLARY FIBROELASTOMAS : Most common tumor of the cardiac valve • SARCOMAS : Most common primary malignant neoplasms in the heart 75% ARE BENiGN
  • 4. 2- Secondary tumors (metastatic): o Much more common than primary cardiac tumors o Most commonly from lung, breast, hematological, melanoma o Cardiac metastases can arise via:  Hematogenous dissemination of cancer cells (i.e. melanoma, lymphoma)  Direct extension via adjacent tissues (i.e. lung)  Propagation to the RA via SVC and IVC (e.g. from renal cancer)  Retrograde lymphatic seeding (i.e. breast carcinoma)
  • 5. Myxoma: ● Myxomas are the most common primary cardiac tumor. ● More than 75% of myxomas originate in the left atrium. ● Macroscopically, atrial myxomas are often pedunculated rounded masses and soft in texture.
  • 6. SYMPTOMS AND SiGNS: 1. Obstructive Symptoms (similar to mitral stenosis): - dyspnea with exertion followed by orthopnea, paroxysmal nocturnal dyspnea, and pulmonary edema. - On physical exam, "tumor plop" may be characteristically heard early in diastole. 2. Thromboembolic Symptoms: Neurologic defects 3. Constitutional Symptoms: fever, malaise, anorexia, arthralgia, weight loss
  • 10. ● Complications: CHF, Arrhythmias, Valvular defects, Thromboembolic Events and infection ● Treatment: Considering the risk of cardiovascular complications and embolization, surgical excision is the treatment of choice for atrial myxomas
  • 11. CREDITS: This presentation template was created by Slidesgo, and includes icons by Flaticon and infographics & images by Freepik Do you have any questions? Jane-nader@buc.edu.eg