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![CARBOHYDRATEMETABOLISM
2ATP (-)
2ATP (+) X 2
2ATP
NET OUTPUT
X 2
[NADH + H+] X 2
6ATP
0ATP
Aerobic
condition
Anaerobic
condition(when in mitochondria)](https://image.slidesharecdn.com/carbohydratemetabolismbiochemistry-200211175834/85/Carbohydrate-Metabolism-11-320.jpg)
![CoA
CO2
NAD
[NADH + H+]
Acetyl-CoA 2C
CARBOHYDRATEMETABOLISM
Pyruvate dehydrogenase
(PDH)](https://image.slidesharecdn.com/carbohydratemetabolismbiochemistry-200211175834/85/Carbohydrate-Metabolism-13-320.jpg)
![Fumerase
NAD+
Acetyl-CoA 2C
CARBOHYDRATEMETABOLISM
[NADH + H+]
Citrate Synthase
CoA
Isocitrate
dehydrogenase
FADH2
FAD
Krebs Cycle
CoA
H2O
Succinate
dehydrogenase
Alphaketoglutarate
dehydrogenase
Succinyl CoA synthase
Malate
dehydrogenase
Aconitase](https://image.slidesharecdn.com/carbohydratemetabolismbiochemistry-200211175834/85/Carbohydrate-Metabolism-14-320.jpg)
Uploaded byDr. Siddharth Dutta
Carbohydrate Metabolism
The document outlines key pathways in carbohydrate metabolism, including glycolysis, the citric acid cycle, gluconeogenesis, and glycogenesis. It details the conversion processes of glucose into energy under both aerobic and anaerobic conditions, emphasizing the roles of specific enzymes and irreversible reactions during these metabolic processes. Additionally, it provides insights into the interplay between different metabolic byproducts and blood glucose regulation.
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Carbohydrate Metabolism
- 1. DR. SIDDHARTH DUTTA(PGT) CARBOHYDRATE METABOLISM
- 2.
- 3. Carbohydrate Metabolism The MajorPathways: Glycolysis Citric Acid Cycle Gluconeogenesis Glycogenesis Glycogenolysis Hexose monophosphate shunt Uronic acid pathway Galactose metabolism Fructose metabolism Amino sugar & mucopolysaccharide metabolism
- 4.
- 5. GYLCOLYSIS (C6H12O6) 2 x(CH3-CO-COOH) Krebs Cycle Fermentation Aerobic condition Anaerobic condition
- 6.
- 7.
- 8.
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- 11. CARBOHYDRATEMETABOLISM 2ATP (-) 2ATP (+)X 2 2ATP NET OUTPUT X 2 [NADH + H+] X 2 6ATP 0ATP Aerobic condition Anaerobic condition(when in mitochondria)
- 12.
- 13. CoA CO2 NAD [NADH + H+] Acetyl-CoA2C CARBOHYDRATEMETABOLISM Pyruvate dehydrogenase (PDH)
- 14. Fumerase NAD+ Acetyl-CoA 2C CARBOHYDRATEMETABOLISM [NADH +H+] Citrate Synthase CoA Isocitrate dehydrogenase FADH2 FAD Krebs Cycle CoA H2O Succinate dehydrogenase Alphaketoglutarate dehydrogenase Succinyl CoA synthase Malate dehydrogenase Aconitase
- 15.
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- 19. CARBOHYDRATEMETABOLISM BLOOD GLUCOSE (6C) PYRUVATE (3C) PYRUVATE GLUCOSE 3 irreversible reactions GLYCOLYSIS 10REACTIONS SPECIFIC ENZYMES can reverse these reactions under special circumstances like FASTING
- 20.
- 21. CARBOHYDRATEMETABOLISM OXALOACETATE Phosphoenol-pyruvate Carboxylase CO2 GTP Fructose 1,6 Bisphosphate Phosphofructokinase PiATP ADP REVERSIBLE REACTIONS Mitochondria OXALOACETATE CO2 ATP Pyruvate carboxylase
- 22.
- 23. Propionate Glycerol CARBOHYDRATEMETABOLISM Succinyl CoA KREBS CYCLE Lactate Lactate Dehydrogenase Reversalprocess continues as explained before. Glycerol 3-phosphate
- 24. 1 23 4 5 O O 1 2 34 5 6 6 P P Glucose6-phosphate Fructose 6-phosphate