The document summarizes the main goals and research projects of the Environmental Microbiology Laboratory led by Dr. Victor de Lorenzo. The lab aims to understand how bacteria respond to environmental signals at the single cell and community levels. It also explores programming bacteria for bioremediation and biosensing applications. Current projects include developing genetic tools to mine biodegradative activities from metagenomes and evolving bacteria to detect explosives in landmines. The lab also works on refactoring metabolic pathways, applying synthetic biology to design arsenic sensing bacteria, and using machine learning to predict biodegradation.