SlideShare a Scribd company logo
MICROME J. Tamames, V. de Lorenzo et al Environmental  Microbiology Laboratory CNB-CSIC, Madrid, Spain
Main goals:    Understanding how bacteria which inhabit natural niches sense and process multiple environmental signals into distinct transcriptional responses –both at the level of single cells and as a community.    Exploring the possibility of programming bacteria for deliberate environmental release aimed at biodegradation of toxic pollutants or as biosensors for monitoring the presence of given chemicals.    Developing tools for the prediction of metabolic outcomes by simulation of single cell or community metabolism Molecular Environmental Microbiology Laboratory Centro Nacional de Biotecnología-National Center of Biotechnology, Madrid, Spain Head: Dr. Victor de Lorenzo
Genetic Traps Mining biodegradative activities out of complex metagenomes, by coupling the rise of the reaction products to transcriptional regulators that activate expression of a marker or reporter gene. Ring monooxygenases: DBT desulphurization:  -HCH dehydrochlorination: Biosensor strains against explosives present in antipersonnel landmines We employ our genetic platforms for evolving transcriptional regulators responsive to residues of explosives  Ongoing research projects +DNT
Refactoring a minimal TOL plasmid. de-construction and re-construction the TOL pathway and its regulatory elements encoded in the pWW0 plasmid of  Pseudomonas putida  mt-2. Ongoing research projects Bioremediation and biosensing of arsenic pollution. Synthetic Biology approach for the design of bacterial strains capable of responding differently to the presence of low and high concentration of arsenic in the medium. Orthogonalization of metabolic modules. The Proteomic Switch: a new strategy to bring about conditional proteomic knockouts in E. coli
Ongoing research projects Logic circuit analysis of the TOL circuit of  P. putida
Predicting biodegradation Gomez et al.  Mol Sys Biol  (2007)‏ Acetaldehyde Solubility:  0.1 g/100 ml MW:  44 D Atomic triads: C-C-H 4 C-C=O 1 H-C-H 3 H-C=O 1 Learning machine C C O H H H H
Environmental and taxonomic diversity Aerial Animal host Artificial Freshwater sediment Freshwater Freshwaters-Saline waters Geothermal Gut Hydrothermal Marine host Oil Oral Other tissue Plants Saline sediment Saline waters Soil Soil-Freshwaters interfase Soil-Saline waters interfase Vagina
http://metagenomics.uv.es/envDB EnvDB database For the study of environmental and taxonomic diversity
GROUP LEADER PROF. VÍCTOR DE LORENZO POSTDOCTORAL BELÉN CALLES AITOR DE LAS HERAS JOSE IGNACIO JIMÉNEZ ESTEBAN MARTÍNEZ JAVIER TAMAMES PREDOCTORAL ALEJANDRO ARCE MAX CHAVARRÍA RAFAEL SILVA-ROCHA TECHNICIANS SOFÍA FRAILE

More Related Content

What's hot

Laccase based biosensors
Laccase based biosensorsLaccase based biosensors
Laccase based biosensors
Anum Rubab
 
Inhibhition of quorum sensing
Inhibhition of quorum sensingInhibhition of quorum sensing
Inhibhition of quorum sensing
PRADIP HIRAPURE
 
NESS 48poster_HF_VF_LN_Final (1)
NESS 48poster_HF_VF_LN_Final (1)NESS 48poster_HF_VF_LN_Final (1)
NESS 48poster_HF_VF_LN_Final (1)
Hilena Frew
 
Bioluminescence assay
Bioluminescence assayBioluminescence assay
Bioluminescence assay
jagrutiSutar
 
displayarticle
displayarticledisplayarticle
displayarticle
Sharon Stewart
 
Marine Bio-Prospecting
Marine Bio-Prospecting Marine Bio-Prospecting
Marine Bio-Prospecting
Thavasimuthu citarasu
 
Metagenomics
MetagenomicsMetagenomics
Metagenomics
P. GAURAV KUMAR
 
Glowing plants
Glowing plantsGlowing plants
Glowing plants
SakshiShiram
 
The influence of rare soil bacteria on plant –herbivore interaction
The influence of rare soil bacteria on plant –herbivore interactionThe influence of rare soil bacteria on plant –herbivore interaction
The influence of rare soil bacteria on plant –herbivore interaction
Sebastian Ayinbisa Yanore
 
Plant microbe interaction review ppt
Plant microbe interaction review pptPlant microbe interaction review ppt
Plant microbe interaction review ppt
Mesele Tilahun
 
Articulos para seminario de biotecnología 2014
Articulos para seminario de biotecnología 2014Articulos para seminario de biotecnología 2014
Articulos para seminario de biotecnología 2014
María de los Ángeles Hernández Loli
 
Impact of heavy metals pollution on molecular genetics of some medicinal plants
Impact of heavy metals pollution on molecular genetics of some medicinal plantsImpact of heavy metals pollution on molecular genetics of some medicinal plants
Impact of heavy metals pollution on molecular genetics of some medicinal plants
IOSRJAVS
 
Enzymesandtheirrolesinthebioremediationbeta 160830082429
Enzymesandtheirrolesinthebioremediationbeta 160830082429Enzymesandtheirrolesinthebioremediationbeta 160830082429
Enzymesandtheirrolesinthebioremediationbeta 160830082429
saurabh verma
 
Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...
Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...
Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...
IJEAB
 
Improving microalgae for biotechnology - from genetics to synthetic biology
Improving  microalgae  for biotechnology  - from genetics to synthetic biologyImproving  microalgae  for biotechnology  - from genetics to synthetic biology
Improving microalgae for biotechnology - from genetics to synthetic biology
nirvarna gr
 
Developement of Nematicide Resistance in Nematodes
Developement of Nematicide Resistance in NematodesDevelopement of Nematicide Resistance in Nematodes
Developement of Nematicide Resistance in Nematodes
Manoranjan Dash
 
Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...
Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...
Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...
Crimsonpublishers-Oceanography
 
Isolation of rhizobium species from soil and to
Isolation of rhizobium species from soil and toIsolation of rhizobium species from soil and to
Isolation of rhizobium species from soil and to
tusha madan
 
Bacteria identification Biosensor
Bacteria identification BiosensorBacteria identification Biosensor
Bacteria identification Biosensor
Oscar1Miranda2
 
Hariom chemotaxis iiiiiii
Hariom chemotaxis iiiiiiiHariom chemotaxis iiiiiii
Hariom chemotaxis iiiiiii
HARIOMGOSWAMI2
 

What's hot (20)

Laccase based biosensors
Laccase based biosensorsLaccase based biosensors
Laccase based biosensors
 
Inhibhition of quorum sensing
Inhibhition of quorum sensingInhibhition of quorum sensing
Inhibhition of quorum sensing
 
NESS 48poster_HF_VF_LN_Final (1)
NESS 48poster_HF_VF_LN_Final (1)NESS 48poster_HF_VF_LN_Final (1)
NESS 48poster_HF_VF_LN_Final (1)
 
Bioluminescence assay
Bioluminescence assayBioluminescence assay
Bioluminescence assay
 
displayarticle
displayarticledisplayarticle
displayarticle
 
Marine Bio-Prospecting
Marine Bio-Prospecting Marine Bio-Prospecting
Marine Bio-Prospecting
 
Metagenomics
MetagenomicsMetagenomics
Metagenomics
 
Glowing plants
Glowing plantsGlowing plants
Glowing plants
 
The influence of rare soil bacteria on plant –herbivore interaction
The influence of rare soil bacteria on plant –herbivore interactionThe influence of rare soil bacteria on plant –herbivore interaction
The influence of rare soil bacteria on plant –herbivore interaction
 
Plant microbe interaction review ppt
Plant microbe interaction review pptPlant microbe interaction review ppt
Plant microbe interaction review ppt
 
Articulos para seminario de biotecnología 2014
Articulos para seminario de biotecnología 2014Articulos para seminario de biotecnología 2014
Articulos para seminario de biotecnología 2014
 
Impact of heavy metals pollution on molecular genetics of some medicinal plants
Impact of heavy metals pollution on molecular genetics of some medicinal plantsImpact of heavy metals pollution on molecular genetics of some medicinal plants
Impact of heavy metals pollution on molecular genetics of some medicinal plants
 
Enzymesandtheirrolesinthebioremediationbeta 160830082429
Enzymesandtheirrolesinthebioremediationbeta 160830082429Enzymesandtheirrolesinthebioremediationbeta 160830082429
Enzymesandtheirrolesinthebioremediationbeta 160830082429
 
Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...
Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...
Isolation and Characterization of Bacteria and Fungi Associated With Biodegra...
 
Improving microalgae for biotechnology - from genetics to synthetic biology
Improving  microalgae  for biotechnology  - from genetics to synthetic biologyImproving  microalgae  for biotechnology  - from genetics to synthetic biology
Improving microalgae for biotechnology - from genetics to synthetic biology
 
Developement of Nematicide Resistance in Nematodes
Developement of Nematicide Resistance in NematodesDevelopement of Nematicide Resistance in Nematodes
Developement of Nematicide Resistance in Nematodes
 
Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...
Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...
Crimson Publishers-Metagenomics to Unlock the Biotechnological Potential of M...
 
Isolation of rhizobium species from soil and to
Isolation of rhizobium species from soil and toIsolation of rhizobium species from soil and to
Isolation of rhizobium species from soil and to
 
Bacteria identification Biosensor
Bacteria identification BiosensorBacteria identification Biosensor
Bacteria identification Biosensor
 
Hariom chemotaxis iiiiiii
Hariom chemotaxis iiiiiiiHariom chemotaxis iiiiiii
Hariom chemotaxis iiiiiii
 

Viewers also liked

Taxonomy, phylogeny, epidemiology rupinder
Taxonomy, phylogeny, epidemiology rupinderTaxonomy, phylogeny, epidemiology rupinder
Taxonomy, phylogeny, epidemiology rupinder
uashish14
 
History, Introduction & Scope Of Microbiology
History, Introduction & Scope Of MicrobiologyHistory, Introduction & Scope Of Microbiology
History, Introduction & Scope Of Microbiology
Salman Ali
 
History and scope
History and scopeHistory and scope
History and scope
Star Reddy
 
Applications of environmental microbiology in industries
Applications of environmental microbiology in industriesApplications of environmental microbiology in industries
Applications of environmental microbiology in industries
Abhishek Rajput
 
environmental microbiology
environmental microbiologyenvironmental microbiology
environmental microbiology
Merlyn Denesia
 
Environmental microbiology
Environmental microbiology Environmental microbiology
Environmental microbiology
Ghassan Hadi
 
Environmental microbiology 2009
Environmental microbiology 2009Environmental microbiology 2009
Environmental microbiology 2009
aiiinura
 
Soil microbiology
Soil microbiologySoil microbiology
Soil microbiology
X S
 
PCR and its types
PCR and  its typesPCR and  its types
PCR and its types
sujathar23
 
atomic absorption spectroscopy
atomic absorption spectroscopyatomic absorption spectroscopy
atomic absorption spectroscopy
sharmasuriti
 

Viewers also liked (10)

Taxonomy, phylogeny, epidemiology rupinder
Taxonomy, phylogeny, epidemiology rupinderTaxonomy, phylogeny, epidemiology rupinder
Taxonomy, phylogeny, epidemiology rupinder
 
History, Introduction & Scope Of Microbiology
History, Introduction & Scope Of MicrobiologyHistory, Introduction & Scope Of Microbiology
History, Introduction & Scope Of Microbiology
 
History and scope
History and scopeHistory and scope
History and scope
 
Applications of environmental microbiology in industries
Applications of environmental microbiology in industriesApplications of environmental microbiology in industries
Applications of environmental microbiology in industries
 
environmental microbiology
environmental microbiologyenvironmental microbiology
environmental microbiology
 
Environmental microbiology
Environmental microbiology Environmental microbiology
Environmental microbiology
 
Environmental microbiology 2009
Environmental microbiology 2009Environmental microbiology 2009
Environmental microbiology 2009
 
Soil microbiology
Soil microbiologySoil microbiology
Soil microbiology
 
PCR and its types
PCR and  its typesPCR and  its types
PCR and its types
 
atomic absorption spectroscopy
atomic absorption spectroscopyatomic absorption spectroscopy
atomic absorption spectroscopy
 

Similar to Cambrige Jan2009 1

Strain improvement technique
Strain improvement techniqueStrain improvement technique
Strain improvement technique
rekha sharma
 
Metagenomic
MetagenomicMetagenomic
Metagenomic
nasim arshadi
 
Control of pollution by genetically engineered microorganisms
Control of pollution by genetically engineered microorganismsControl of pollution by genetically engineered microorganisms
Control of pollution by genetically engineered microorganisms
Samar Biswas
 
Molecular Environmental Microbiology.ppt
Molecular Environmental Microbiology.pptMolecular Environmental Microbiology.ppt
Molecular Environmental Microbiology.ppt
Huma Hameed
 
Bioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putida
Bioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putidaBioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putida
Bioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putida
International Journal of Innovation Engineering and Science Research
 
Gonzalez2008 Res Microb
Gonzalez2008 Res MicrobGonzalez2008 Res Microb
Gonzalez2008 Res Microb
guest74ede4c
 
Micromotors to capture and destroy anthrax simulant spores
Micromotors to capture and destroy anthrax simulant sporesMicromotors to capture and destroy anthrax simulant spores
Micromotors to capture and destroy anthrax simulant spores
Michael Galarnyk
 
metagenomics
metagenomicsmetagenomics
metagenomics
Ghooda Shaqour
 
Applications of environmental biotechnology by Hameer Khan
Applications of environmental biotechnology by Hameer KhanApplications of environmental biotechnology by Hameer Khan
Applications of environmental biotechnology by Hameer Khan
Humair Sindhi
 
JBEI Research Highlights - May 2019
JBEI Research Highlights - May 2019JBEI Research Highlights - May 2019
JBEI Research Highlights - May 2019
Irina Silva
 
poster dulce chavez SMWC 2
poster dulce chavez SMWC 2poster dulce chavez SMWC 2
poster dulce chavez SMWC 2
Dulce Chavez
 
Finally its Over! Feeling Happy.
Finally its Over! Feeling Happy.Finally its Over! Feeling Happy.
Finally its Over! Feeling Happy.
Dhirend N. Singh
 
Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...
Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...
Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...
eSAT Journals
 
Metagenomics sk presentation 17.10.2017
Metagenomics sk presentation 17.10.2017 Metagenomics sk presentation 17.10.2017
Metagenomics sk presentation 17.10.2017
SUNILKUMARSAHOO16
 
JBEI Research Highlights Slides - October 2022
JBEI Research Highlights Slides - October 2022JBEI Research Highlights Slides - October 2022
JBEI Research Highlights Slides - October 2022
SaraHarmon4
 
Metagenomic
MetagenomicMetagenomic
Metagenomic
kumarkanika
 
Metagenomics by microbiology dept. panjab university2018copy
Metagenomics by microbiology dept. panjab university2018copyMetagenomics by microbiology dept. panjab university2018copy
Metagenomics by microbiology dept. panjab university2018copy
deepankarshashni
 
Nanobiotechnology,Nanotechnology,Biological pores
Nanobiotechnology,Nanotechnology,Biological poresNanobiotechnology,Nanotechnology,Biological pores
Nanobiotechnology,Nanotechnology,Biological pores
Nimisha Tehri
 
Environmental Biotechnology
Environmental BiotechnologyEnvironmental Biotechnology
Environmental Biotechnology
Ravi Dhande
 
Applications of Environmental biotechnology.pptx
Applications of Environmental biotechnology.pptxApplications of Environmental biotechnology.pptx
Applications of Environmental biotechnology.pptx
AaryanGupta23
 

Similar to Cambrige Jan2009 1 (20)

Strain improvement technique
Strain improvement techniqueStrain improvement technique
Strain improvement technique
 
Metagenomic
MetagenomicMetagenomic
Metagenomic
 
Control of pollution by genetically engineered microorganisms
Control of pollution by genetically engineered microorganismsControl of pollution by genetically engineered microorganisms
Control of pollution by genetically engineered microorganisms
 
Molecular Environmental Microbiology.ppt
Molecular Environmental Microbiology.pptMolecular Environmental Microbiology.ppt
Molecular Environmental Microbiology.ppt
 
Bioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putida
Bioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putidaBioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putida
Bioremediation of soils polluted by petroleum hydrocarbons by Pseudomonas putida
 
Gonzalez2008 Res Microb
Gonzalez2008 Res MicrobGonzalez2008 Res Microb
Gonzalez2008 Res Microb
 
Micromotors to capture and destroy anthrax simulant spores
Micromotors to capture and destroy anthrax simulant sporesMicromotors to capture and destroy anthrax simulant spores
Micromotors to capture and destroy anthrax simulant spores
 
metagenomics
metagenomicsmetagenomics
metagenomics
 
Applications of environmental biotechnology by Hameer Khan
Applications of environmental biotechnology by Hameer KhanApplications of environmental biotechnology by Hameer Khan
Applications of environmental biotechnology by Hameer Khan
 
JBEI Research Highlights - May 2019
JBEI Research Highlights - May 2019JBEI Research Highlights - May 2019
JBEI Research Highlights - May 2019
 
poster dulce chavez SMWC 2
poster dulce chavez SMWC 2poster dulce chavez SMWC 2
poster dulce chavez SMWC 2
 
Finally its Over! Feeling Happy.
Finally its Over! Feeling Happy.Finally its Over! Feeling Happy.
Finally its Over! Feeling Happy.
 
Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...
Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...
Microbial community analysis in anaerobic palm oil mill effluent (pome) waste...
 
Metagenomics sk presentation 17.10.2017
Metagenomics sk presentation 17.10.2017 Metagenomics sk presentation 17.10.2017
Metagenomics sk presentation 17.10.2017
 
JBEI Research Highlights Slides - October 2022
JBEI Research Highlights Slides - October 2022JBEI Research Highlights Slides - October 2022
JBEI Research Highlights Slides - October 2022
 
Metagenomic
MetagenomicMetagenomic
Metagenomic
 
Metagenomics by microbiology dept. panjab university2018copy
Metagenomics by microbiology dept. panjab university2018copyMetagenomics by microbiology dept. panjab university2018copy
Metagenomics by microbiology dept. panjab university2018copy
 
Nanobiotechnology,Nanotechnology,Biological pores
Nanobiotechnology,Nanotechnology,Biological poresNanobiotechnology,Nanotechnology,Biological pores
Nanobiotechnology,Nanotechnology,Biological pores
 
Environmental Biotechnology
Environmental BiotechnologyEnvironmental Biotechnology
Environmental Biotechnology
 
Applications of Environmental biotechnology.pptx
Applications of Environmental biotechnology.pptxApplications of Environmental biotechnology.pptx
Applications of Environmental biotechnology.pptx
 

Recently uploaded

UiPath Test Automation using UiPath Test Suite series, part 6
UiPath Test Automation using UiPath Test Suite series, part 6UiPath Test Automation using UiPath Test Suite series, part 6
UiPath Test Automation using UiPath Test Suite series, part 6
DianaGray10
 
Microsoft - Power Platform_G.Aspiotis.pdf
Microsoft - Power Platform_G.Aspiotis.pdfMicrosoft - Power Platform_G.Aspiotis.pdf
Microsoft - Power Platform_G.Aspiotis.pdf
Uni Systems S.M.S.A.
 
DevOps and Testing slides at DASA Connect
DevOps and Testing slides at DASA ConnectDevOps and Testing slides at DASA Connect
DevOps and Testing slides at DASA Connect
Kari Kakkonen
 
Elizabeth Buie - Older adults: Are we really designing for our future selves?
Elizabeth Buie - Older adults: Are we really designing for our future selves?Elizabeth Buie - Older adults: Are we really designing for our future selves?
Elizabeth Buie - Older adults: Are we really designing for our future selves?
Nexer Digital
 
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdf
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdfUnlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdf
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdf
Malak Abu Hammad
 
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex Proofs
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex ProofszkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex Proofs
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex Proofs
Alex Pruden
 
Large Language Model (LLM) and it’s Geospatial Applications
Large Language Model (LLM) and it’s Geospatial ApplicationsLarge Language Model (LLM) and it’s Geospatial Applications
Large Language Model (LLM) and it’s Geospatial Applications
Rohit Gautam
 
Generative AI Deep Dive: Advancing from Proof of Concept to Production
Generative AI Deep Dive: Advancing from Proof of Concept to ProductionGenerative AI Deep Dive: Advancing from Proof of Concept to Production
Generative AI Deep Dive: Advancing from Proof of Concept to Production
Aggregage
 
Epistemic Interaction - tuning interfaces to provide information for AI support
Epistemic Interaction - tuning interfaces to provide information for AI supportEpistemic Interaction - tuning interfaces to provide information for AI support
Epistemic Interaction - tuning interfaces to provide information for AI support
Alan Dix
 
By Design, not by Accident - Agile Venture Bolzano 2024
By Design, not by Accident - Agile Venture Bolzano 2024By Design, not by Accident - Agile Venture Bolzano 2024
By Design, not by Accident - Agile Venture Bolzano 2024
Pierluigi Pugliese
 
Securing your Kubernetes cluster_ a step-by-step guide to success !
Securing your Kubernetes cluster_ a step-by-step guide to success !Securing your Kubernetes cluster_ a step-by-step guide to success !
Securing your Kubernetes cluster_ a step-by-step guide to success !
KatiaHIMEUR1
 
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AI
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AIEnchancing adoption of Open Source Libraries. A case study on Albumentations.AI
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AI
Vladimir Iglovikov, Ph.D.
 
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...
DanBrown980551
 
GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...
GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...
GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...
Neo4j
 
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...
James Anderson
 
PCI PIN Basics Webinar from the Controlcase Team
PCI PIN Basics Webinar from the Controlcase TeamPCI PIN Basics Webinar from the Controlcase Team
PCI PIN Basics Webinar from the Controlcase Team
ControlCase
 
GraphSummit Singapore | The Art of the Possible with Graph - Q2 2024
GraphSummit Singapore | The Art of the  Possible with Graph - Q2 2024GraphSummit Singapore | The Art of the  Possible with Graph - Q2 2024
GraphSummit Singapore | The Art of the Possible with Graph - Q2 2024
Neo4j
 
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdf
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfObservability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdf
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdf
Paige Cruz
 
みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...
みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...
みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...
名前 です男
 
Uni Systems Copilot event_05062024_C.Vlachos.pdf
Uni Systems Copilot event_05062024_C.Vlachos.pdfUni Systems Copilot event_05062024_C.Vlachos.pdf
Uni Systems Copilot event_05062024_C.Vlachos.pdf
Uni Systems S.M.S.A.
 

Recently uploaded (20)

UiPath Test Automation using UiPath Test Suite series, part 6
UiPath Test Automation using UiPath Test Suite series, part 6UiPath Test Automation using UiPath Test Suite series, part 6
UiPath Test Automation using UiPath Test Suite series, part 6
 
Microsoft - Power Platform_G.Aspiotis.pdf
Microsoft - Power Platform_G.Aspiotis.pdfMicrosoft - Power Platform_G.Aspiotis.pdf
Microsoft - Power Platform_G.Aspiotis.pdf
 
DevOps and Testing slides at DASA Connect
DevOps and Testing slides at DASA ConnectDevOps and Testing slides at DASA Connect
DevOps and Testing slides at DASA Connect
 
Elizabeth Buie - Older adults: Are we really designing for our future selves?
Elizabeth Buie - Older adults: Are we really designing for our future selves?Elizabeth Buie - Older adults: Are we really designing for our future selves?
Elizabeth Buie - Older adults: Are we really designing for our future selves?
 
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdf
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdfUnlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdf
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdf
 
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex Proofs
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex ProofszkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex Proofs
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex Proofs
 
Large Language Model (LLM) and it’s Geospatial Applications
Large Language Model (LLM) and it’s Geospatial ApplicationsLarge Language Model (LLM) and it’s Geospatial Applications
Large Language Model (LLM) and it’s Geospatial Applications
 
Generative AI Deep Dive: Advancing from Proof of Concept to Production
Generative AI Deep Dive: Advancing from Proof of Concept to ProductionGenerative AI Deep Dive: Advancing from Proof of Concept to Production
Generative AI Deep Dive: Advancing from Proof of Concept to Production
 
Epistemic Interaction - tuning interfaces to provide information for AI support
Epistemic Interaction - tuning interfaces to provide information for AI supportEpistemic Interaction - tuning interfaces to provide information for AI support
Epistemic Interaction - tuning interfaces to provide information for AI support
 
By Design, not by Accident - Agile Venture Bolzano 2024
By Design, not by Accident - Agile Venture Bolzano 2024By Design, not by Accident - Agile Venture Bolzano 2024
By Design, not by Accident - Agile Venture Bolzano 2024
 
Securing your Kubernetes cluster_ a step-by-step guide to success !
Securing your Kubernetes cluster_ a step-by-step guide to success !Securing your Kubernetes cluster_ a step-by-step guide to success !
Securing your Kubernetes cluster_ a step-by-step guide to success !
 
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AI
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AIEnchancing adoption of Open Source Libraries. A case study on Albumentations.AI
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AI
 
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...
 
GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...
GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...
GraphSummit Singapore | Enhancing Changi Airport Group's Passenger Experience...
 
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...
 
PCI PIN Basics Webinar from the Controlcase Team
PCI PIN Basics Webinar from the Controlcase TeamPCI PIN Basics Webinar from the Controlcase Team
PCI PIN Basics Webinar from the Controlcase Team
 
GraphSummit Singapore | The Art of the Possible with Graph - Q2 2024
GraphSummit Singapore | The Art of the  Possible with Graph - Q2 2024GraphSummit Singapore | The Art of the  Possible with Graph - Q2 2024
GraphSummit Singapore | The Art of the Possible with Graph - Q2 2024
 
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdf
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfObservability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdf
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdf
 
みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...
みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...
みなさんこんにちはこれ何文字まで入るの?40文字以下不可とか本当に意味わからないけどこれ限界文字数書いてないからマジでやばい文字数いけるんじゃないの?えこ...
 
Uni Systems Copilot event_05062024_C.Vlachos.pdf
Uni Systems Copilot event_05062024_C.Vlachos.pdfUni Systems Copilot event_05062024_C.Vlachos.pdf
Uni Systems Copilot event_05062024_C.Vlachos.pdf
 

Cambrige Jan2009 1

  • 1. MICROME J. Tamames, V. de Lorenzo et al Environmental Microbiology Laboratory CNB-CSIC, Madrid, Spain
  • 2. Main goals:  Understanding how bacteria which inhabit natural niches sense and process multiple environmental signals into distinct transcriptional responses –both at the level of single cells and as a community.  Exploring the possibility of programming bacteria for deliberate environmental release aimed at biodegradation of toxic pollutants or as biosensors for monitoring the presence of given chemicals.  Developing tools for the prediction of metabolic outcomes by simulation of single cell or community metabolism Molecular Environmental Microbiology Laboratory Centro Nacional de Biotecnología-National Center of Biotechnology, Madrid, Spain Head: Dr. Victor de Lorenzo
  • 3. Genetic Traps Mining biodegradative activities out of complex metagenomes, by coupling the rise of the reaction products to transcriptional regulators that activate expression of a marker or reporter gene. Ring monooxygenases: DBT desulphurization:  -HCH dehydrochlorination: Biosensor strains against explosives present in antipersonnel landmines We employ our genetic platforms for evolving transcriptional regulators responsive to residues of explosives Ongoing research projects +DNT
  • 4. Refactoring a minimal TOL plasmid. de-construction and re-construction the TOL pathway and its regulatory elements encoded in the pWW0 plasmid of Pseudomonas putida mt-2. Ongoing research projects Bioremediation and biosensing of arsenic pollution. Synthetic Biology approach for the design of bacterial strains capable of responding differently to the presence of low and high concentration of arsenic in the medium. Orthogonalization of metabolic modules. The Proteomic Switch: a new strategy to bring about conditional proteomic knockouts in E. coli
  • 5. Ongoing research projects Logic circuit analysis of the TOL circuit of P. putida
  • 6. Predicting biodegradation Gomez et al. Mol Sys Biol (2007)‏ Acetaldehyde Solubility: 0.1 g/100 ml MW: 44 D Atomic triads: C-C-H 4 C-C=O 1 H-C-H 3 H-C=O 1 Learning machine C C O H H H H
  • 7. Environmental and taxonomic diversity Aerial Animal host Artificial Freshwater sediment Freshwater Freshwaters-Saline waters Geothermal Gut Hydrothermal Marine host Oil Oral Other tissue Plants Saline sediment Saline waters Soil Soil-Freshwaters interfase Soil-Saline waters interfase Vagina
  • 8. http://metagenomics.uv.es/envDB EnvDB database For the study of environmental and taxonomic diversity
  • 9. GROUP LEADER PROF. VÍCTOR DE LORENZO POSTDOCTORAL BELÉN CALLES AITOR DE LAS HERAS JOSE IGNACIO JIMÉNEZ ESTEBAN MARTÍNEZ JAVIER TAMAMES PREDOCTORAL ALEJANDRO ARCE MAX CHAVARRÍA RAFAEL SILVA-ROCHA TECHNICIANS SOFÍA FRAILE