Rickets is a softening of the bones caused by vitamin D deficiency, with symptoms like bowed legs and joint pain. It is caused by deficiencies in vitamin D, calcium, and phosphorus, and risk factors include dark skin, premature birth, and anti-seizure medications. Without treatment, rickets can lead to skeletal deformities and stunted growth. Current treatments include vitamin D and calcium supplements, while the author suggests additionally giving breastfeeding infants daily vitamin D drops and increasing parathyroid hormone production to help treat rickets.

1. New suggested treatment of

2.  Definition
 Symptoms
 Causes
 Risk factors
 Complications
 Mechanism of vitamine D production
 Mechanism of rickets
 Present treatment
 My suggestion

3.  Rickets is the softening and weakening of
bones in children, usually because of an
extreme and prolonged vitamin D deficiency.

4.  Delayed growth
 Pain in the spine, pelvis and legs
 Muscle weakness
 Bowed legs
 Thickened wrists and ankles
 Breastbone projection

5. Deficiency in
 Vitamin D
 Calcium
 phosphorous

6.  Age
 Dark skin
 Premature birth
 Anti-seizure medications
 Exclusive breast-feeding.

7.  If left untreated, rickets may lead to:
 Failure to grow
 Abnormally curved spine
 Skeletal deformities
 Dental defects
 Seizures

13.  vitamin D and calcium supplements
 Surgical and other procedures

15.  During breast feeding give oral vitamin D
daily(400 IU drops)
 Increase the activity of 1 α hydroxylase
 Decreased the activity of 24 hydroxylase

16.  Rocaltrol
Which is commonly used in managment of
hyperparathyriodism
Also enhances calcium absorption

17.  Calderol
commonly used as hypoparathyroid agents
in some areas also used as vitamin d in the
treatment of rickets

18.  PTH increases the activity of 1-α-
hydroxylase enzyme, which converts 25-
hydroxycholecalciferol to 1,25-
dihydroxycholecalciferol, the active form
of vitamin D.

20.  We can increase the production of parathroid
hormone

21.  http://www.mayoclinic.com
 http://www.betterhealth.com
 http://www.rxlist.com
 Journal of immunology Baltimore,Md:1950