This document provides best practices for making your first cloud deployment successful. It discusses organizational structure, management tools, understanding virtual machine density limits, network operations, storage choices, templates, and defining service offerings. Key lessons are to know your application requirements, optimize for your needs rather than just using public clouds, ensure backup plans, and clearly define service level agreements and compliance expectations. Infrastructure choices like hypervisors and primary storage should fit the defined service offerings. Operations should focus on monitoring, maintainability with no maintenance windows, and adapting as usage grows over time.