The document describes the sulci and gyri of the cerebral hemispheres. It outlines the three surfaces (lateral, medial, inferior), borders, poles (frontal, temporal, occipital), and lobes (frontal, parietal, temporal, occipital) of the hemispheres. It then details the major sulci that divide the cortex into gyri in each lobe, including the central sulcus, lateral sulcus, and parieto-occipital sulcus. Finally, it describes important structures on the medial and inferior surfaces such as the cingulate gyrus, paracentral lobule, and collateral sulcus.
introduction of neck and boundaries of neck , superficial fascia and structures present with in it, deep cervical fascia types and most importantly spaces with in it mainly about Retro-pharyngeal spaces and applied anatomy along with incision markings.
gross Anatomy of Mid Brain.location an relation of midbrain. external an internal features of mid brain. cross section at the level of superior and inferior colliculus. Anterior and posterior view of midbrain.
clinical correlation of midbrain.
CERVICAL PART OF SYMPATHETIC TRUNK
https://www.slideshare.net/DRCAPRICORN/slideshelf
VESSICO-BULLOUS DISORDER LECTURE : https://youtu.be/lgizglcWJ9I
HOOVER SIGN for leg paresis/ copd=
https://youtu.be/v-rT80AksZw
BEEVOR SIGN = https://youtu.be/QTBqQ31KqUA
ALL PERIPHERAL SIGN'S OF AORTIC REGURGITATION=
https://youtu.be/JZBQGsmK4dY
SUBSCRIBE US ON YOUTUBE : www.youtube.com/c/DrCapricorn
the ddep structure of brain, diencephalon, third ventricle, thalamus, hypothalamus, epithalamus, meta thalamus, boudaries of diencephalon, extent of diencephalon, boundaries of thalamus, boundaries of hypothalamus, functions of meta thalamus, functions of sub thalamus.components of epithalamus, functions of epithalamus, fornix, third ventricle, optic chiasma,
Lateral ventricle of Brain. By Dr.N.Mugunthan.M.Smgmcri1234
Lateral ventricle of brain. Lecture by Dr.N.Mugunthan.
Associate Professor,
Mahatma Gandhi Medical College & Research Institute,
Sri Balaji Vidyapeeth, Pondicherry.
introduction of neck and boundaries of neck , superficial fascia and structures present with in it, deep cervical fascia types and most importantly spaces with in it mainly about Retro-pharyngeal spaces and applied anatomy along with incision markings.
gross Anatomy of Mid Brain.location an relation of midbrain. external an internal features of mid brain. cross section at the level of superior and inferior colliculus. Anterior and posterior view of midbrain.
clinical correlation of midbrain.
CERVICAL PART OF SYMPATHETIC TRUNK
https://www.slideshare.net/DRCAPRICORN/slideshelf
VESSICO-BULLOUS DISORDER LECTURE : https://youtu.be/lgizglcWJ9I
HOOVER SIGN for leg paresis/ copd=
https://youtu.be/v-rT80AksZw
BEEVOR SIGN = https://youtu.be/QTBqQ31KqUA
ALL PERIPHERAL SIGN'S OF AORTIC REGURGITATION=
https://youtu.be/JZBQGsmK4dY
SUBSCRIBE US ON YOUTUBE : www.youtube.com/c/DrCapricorn
the ddep structure of brain, diencephalon, third ventricle, thalamus, hypothalamus, epithalamus, meta thalamus, boudaries of diencephalon, extent of diencephalon, boundaries of thalamus, boundaries of hypothalamus, functions of meta thalamus, functions of sub thalamus.components of epithalamus, functions of epithalamus, fornix, third ventricle, optic chiasma,
Lateral ventricle of Brain. By Dr.N.Mugunthan.M.Smgmcri1234
Lateral ventricle of brain. Lecture by Dr.N.Mugunthan.
Associate Professor,
Mahatma Gandhi Medical College & Research Institute,
Sri Balaji Vidyapeeth, Pondicherry.
Neurosurgery involving the cerebrum, the largest and most prominent part of the brain, encompasses a wide range of procedures aimed at addressing various neurological conditions.
The cerebrum is responsible for higher cognitive functions, sensory perception, motor control, and emotional processing.
Neurosurgery involving the cerebrum requires a multidisciplinary approach, combining neuroimaging, neurophysiology, and advanced surgical techniques to address diverse neurological conditions while preserving critical brain functions.
cerebrum, sulci and gyri of cerebrum, lobes of cerebrum, frontal lobe , parietal lobe, temporal lobe and occipital lobe, sulci and gyri presnet in each lobes, and the functional areas , of cerebrum, brodmann areas of cerebrum, borders and surfaces of cerebrum, insula,
the division of abdominal cavities in to different compartments and quadrants by using vertical and horizontal lines, such as supra colic and infra colic compartments , four quadrants, nine quadrants. and the organs present in each compartments respectively.
PERITONEUM AND THE COMPONENTS OF PERITONEUM.pptxDr. sana yaseen
anatomy of peritoneum and the peritoneal cavity. the modification of peritoneum and the structures associated with peritoneum such as, omentum, mesentry mesocolon, epiploic foramen, pouches, peritoneal ligaments, and folds and recesses.
anatomy of larynx, including the spaces associated with larynx the muscles and the paired unpaired cartilages, the attachment of the muscles and the associated functions . true and false vocal cords and the clinical pathology associated with larynx . the blood supply, nerve supply and the lymphatic drainage of the larynx
anterior and posterior triangles of the neck. the boundaries and contents of anterior and posterior triangle. divisions of anterior triangle as carotid triangle, muscular triangle, submental triangle, digastric triangle. division of posterior triangle as occipital triangle, subclavian triangle
dural venous sinus, their location, position and contents passing through important sinuses. their tributaries and drainage. paired unpaired sinuses. and there clinical correlation.
Anatomy of urinary bladder. surfaces, border of urinary bladder its relation , ligament support, peritoneal relation in male and females, pouches, blood supply of bladder, nerve supply of bladder, true and false ligament of urinary bladder,
gross Anatomy of kidney, description of external and internal structure of kidney, the relation of right and left kidney. difference between right and left kidney, and some clinical abnormalities relate to kidney,
anatomy of suboccipital triangle, bounaries roof and floor of the suboccipital triangle, contents of the triangle, cervical plexus, muscular andd sensory branches of cervical plexus
anatomy of hard palate an soft palate. boundaries of hard and soft palate, blood supply, nerve supply .
osteology of hard palate, muscles of soft palate. origin, insertion of muscles of soft palate, action of muscles of soft palate, pasavants ridge
lesions of the spinal cord. differences between upper and lower motor neuron lesions. brownsequard syndrome, poliomyelitis, multiple sclerosis, complete cord lesion,
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2. INTRODUCTION
•The cerebral hemispheres constitute the
largest part of the brain
•Divided into right and left hemispheres.
•The hemispheres are separated medially by a
deep cleft, named the longitudinal cerebral
fissure
•Linked by corpus callosum.
4. BORDERS OF CEREBRAL HEMISPHERE
3 surfaces are separated by the following borders:
(a) Supero-medial, between the lateral and medial surfaces.
(b) Infero-lateral, between the lateral and inferior surfaces; the
anterior part of this border separating the lateral from the orbital
surface, is known as the superciliary border.
(c) Medial occipital, separating the medial and tentorial surfaces.
(d) Medial orbital, separating the orbital from the medial surface
5. POLES OF CEREBRAL HEMISPHERE
• Frontal pole: anterior end of
hemisphere.
• Temporal pole: anterior end
of temporal lobe.
• Occipital pole: posterior
end of hemisphere.
7. SULCI AND GYRI
• SULCI: shallow depressions
present on the cerebral cortex
dividing brain on basis of
functional areas
• GYRI: are the irregular
eminences present on the brain
substance between the two
sulci.
• FISSURES: are the deeper
depressions.
8. SULCI AND GYRI PRESENT IN CEREBRAL
HEMISPHERE
Central sulcus
• Middle of the lateral surface
• Divides frontal and parietal lobe
• Precentral gyrus contains motor
area
• Postcentral gyrus contain sensory
area.
9.
10. Lateral sulcus
•Divides frontal and parietal
lobes above from temporal lobe
•Lateral sulcus further divides
into
•Anterior horizontal ramus
•Anterior ascending ramus
•Posterior ramus
11. Parieto-occipital sulcus
• lateral surface in front of occipital pole
• Medial surface
Calcarine sulcus
• Found on the medial surface
• Starts behind corpus callosum
• Arches back to the occipital pole
12.
13. SULCI AND GYRI IN
• Frontal lobe
Three sulci divides it into four gyri
• Precentral sulcus
• Superior frontal sulcus
• Inferior frontal sulcus
• Superior frontal gyrus
• Middle frontal gyrus
• Inferior frontal gyrus
• Precentral gyrus
Parietal lobe
2 sulci divides into 3 gyri
• Post central sulcus
• Intraparietal sulcus
• Post central gyrus
• Supra parietal lobule
• Infraparietal lobule
Plays role in integrating sensory
information from various parts of the
body, knowledge of numbers and their
relations, and in the manipulation of
objects.
14. • Temporal lobe
2 sulci divides it into 3 gyri
• Superior temporal sulcus
• Middle temporal sulcus
• Superior temporal gyrus
• Mid temporal gyrus
• Inferior temporal gyrus
• The temporal lobe is involved in
auditory perception and is home to
the primary auditory cortex
Occipital lobe
o Smallest lobe
o Lateral occipital gyri
o Lateral occipital
sulci
o Visual processing
cortex
15.
16. MEDIAL AND INFERIOR SURFACE
Important structures on the medial surface
• Corpus callosum
• Cingulate gyrus
• Callosal gyrus
• Paracentral lobule
• Precuneus
• Cuneus
• Collateral sulcus
• Medial occipitotemporal gyrus
17. Cingulate gyrus
• Starts beneath the corpus callosum and goes back above it and ends
at the posterior end of it.
• Callosal sulcus
• Separates corpus callosum from cingulate gyrus
• Cingulate sulcus
• Separates cingulate gyrus from superior frontal gyrus
18. Paracentral lobule
• Area of brain that surrounds the
indentation formed by the central
sulcus on the superior border
• Anterior part = precentral gyrus
• Posterior part = postcentral
gyrus
• Cuneus and precuneus
o Precuneus
o Anteriorly = upturned end of
cingulate sulcus
o Posterioly = parieto-occipital
sulcus
o Cuneus
o Triangular area between parieto-
occipital sulcus and calcarine
sulcus
19.
20. Collateral sulcus and
lingual gyrus
• On inferior surface
• Lingual gyrus
• Between collateral sulcus
and calcarine sulcus
• Parahippocampal gyrus
• Anterior to lingual gyrus
Medial occipito-temporal gyrus
• From occipital pole to temporal
pole
• Medially by collateral sulcus
• Laterally by occipitotemporal
sulcus
• Continuous with inferior
temporal gyrus