Bone cancer is a rare type of cancer that begins in the bones, most commonly affecting the long bones of the arms and legs. Some common types of bone cancer include osteosarcoma, Ewing sarcoma, and malignant fibrous histiocytoma. Symptoms include bone pain, tenderness, broken bones, fatigue, and unintended weight loss. Risk factors include smoking, age, race, and prior radiation treatment. Treatment options for bone cancer include chemotherapy, radiation therapy, and surgery. Prevention methods involve maintaining a healthy lifestyle through diet, exercise, and avoiding tobacco and excessive sun exposure.