In 2022, around 1.9 million US population were diagnosed with cancer. From the number, it is obvious that cancer is part of the most common diseases and also one of the deadliest diseases. Although there are different types of cancer, a few of the most common ones include skin, breast, and lung cancer. Out of all these common ones, there is one cancer that is quite rare in individuals and only makes up less than one per cent of all cancers. This cancer is commonly known as bone cancer or Osteosarcoma.
This article clarifies regarding Bone Cancer could be a tough and savage malady. In any case, this will be rebuilt in starting times effectively. thus this text provides you knowledge known with bone malignancy, Sigs or facet effects of the bone malady, what could be the explanations for bone malignant growth, however oft will it happen, what treatment selection do patients have, what are the most effective healing centers for the Bone Cancer Treatment.
Bone cancer or bone marrow cancer has many types and develops in various ages of life. We have provided an elaborate guide to bone cancer treatment, Symptoms, causes, hospitals.
this article gives you data identified with bone malignancy, Sigs or side effects of bone disease, what might be the reasons for bone malignant growth, How frequently does it happen, what treatment choice do patients have, what are the best healing centers for the Bone Cancer Treatment.
This article clarifies regarding Bone Cancer could be a tough and savage malady. In any case, this will be rebuilt in starting times effectively. thus this text provides you knowledge known with bone malignancy, Sigs or facet effects of the bone malady, what could be the explanations for bone malignant growth, however oft will it happen, what treatment selection do patients have, what are the most effective healing centers for the Bone Cancer Treatment.
Bone cancer or bone marrow cancer has many types and develops in various ages of life. We have provided an elaborate guide to bone cancer treatment, Symptoms, causes, hospitals.
this article gives you data identified with bone malignancy, Sigs or side effects of bone disease, what might be the reasons for bone malignant growth, How frequently does it happen, what treatment choice do patients have, what are the best healing centers for the Bone Cancer Treatment.
• Modern Homeopathy has been providing treatment for Cancer, Liver Cirrhosis, Kidney failure, Heart diseases, Diabetes, Arthritis, Blood disorders, Lung diseases, and many others with painless treatment and reviving those lives who have lost the faith in their life. The practice of homeopathy is based on the principle that like cures.
Metastatic Bone Disease & Role of Zoledronic AcidMRINMOY ROY
Metastatic Bone Disease is Cancer that begins in an organ, such as the lungs, breast, or prostate, and then spreads to bone.
More than 1.2 million new cancer cases are diagnosed each year. Approximately 50% of these tumours can spread (metastasize) to the skeleton.
With improved medical treatment of many cancers — especially breast, lung, and prostate — patients are living longer. However, the primary cancers in more of these patients are spreading to bone. The tumours that result are called bone metastases.
Here the role of Zoledronic Acid have been fall in place in treatment.
Bone Cancer is in fact a very uncommon type of cancer which begins in the bone. Although, this cancer can begin within any bone in the body, but is found to most commonly affect the longer bones which make up for the arms & legs.
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Neuroendocrine tumors in the liver can present in a variety of ways, making diagnosis challenging without proper screening protocols. Unfortunately, many patients only show symptoms when the NET is at a later stage, leading to worse prognoses. However, recent advancements in medical technology, such as ultrasounds and PET scans, can aid in early detection of NETs in the liver. Additionally, with better understanding of the genetic and molecular makeup of these tumors, targeted therapies can be developed for more effective treatment.
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
3. HOW LONG CAN YOU HAVE BONE CANCER WITHOUT KNOWING
(BRIEF GUIDE)?
What Is Bone Cancer?
What Are The Various Types Of Bone Cancer?
What Makes Bone Cancer Get Unattended For So Long?
Common Signs And Symptoms Of Bone Cancer
What Are The Causes Of Bone Cancer?
What Are The Risk Factors For Bone Tumor or Cancer?
Staging And Diagnosing Bone Cancer
How Can You Treat Bone Cancer?
Is Bone Cancer Fatal? What’s The Survival Rate Of Bone Cancer?
4. What Is Bone Cancer?
When we talk about bone cancer, you should know that this term is used for various cancers that develop in a person’s
bones. The development of cancer cells in your bone can damage the bone tissue. Since bone cancer is a broad term,
you might want to know how doctors determine the bone cancer type you have. It’s actually determined based on your
tissue, and cell type cancer started developing.
Cancers that originate from the bone itself are known as primary bone cancers. There are also tumors that start
developing from organs as well as the other parts of the body, which later spread to the bones and other parts. These
growths of cancer cells are referred to as metastatic or secondary bone cancers. In most cases, the lung, prostate, and
breast tumors spread or metastasize to the bones.
Cancers that originate from the bone itself are known as primary bone cancers. There are also tumors that start
developing from organs as well as the other parts of the body, which later spread to the bones and other parts. These
growths of cancer cells are referred to as metastatic or secondary bone cancers. In most cases, the lung, prostate, and
breast tumors spread or metastasize to the bones.
5. What Are The Various Types Of Bone Cancer?
•Osteogenic Sarcoma (Osteosarcoma)
This type of bone cancer is more common in children and adolescents. However, Osteosarcoma can even happen in
adults. In the maximum number of cases, this cancer starts developing at the long bone tips in the legs and arms. This
cancer harms the hard tissue that works as outer layer protection for your bones. Furthermore, osteogenic sarcoma may
develop in your shoulders, hips, and other locations.
•Ewing’s Sarcoma
We have Ewing’s sarcoma as the second number in our common primary bone cancer list. This cancer originates from the
soft tissue close to the bones or even directly in the bones. You will find this cancer more common in young adults as well
as children. Normally, it affects the person’s long bones like legs, arms as well as pelvis.
Chondrosarcoma
Chondrosarcoma is more common among older adults and usually develops in the thigh, shoulders, and pelvis areas. It
develops in the subchondral tissue, a tough connective tissue between a person’s bones. However, its rare cases make it
the least common primary bone cancer.
•Multiple Myeloma
MM (Multiple myeloma) is known to be the most common cancer type, which involves bones. But, this cancer is not part
of primary bone cancer since it originates in the plasma cells. This cancer happens when cancer cells develop in a person’s
bone marrow, leading to tumors in different bones. MM is more common in older adults.
6. What Makes Bone Cancer Get Unattended For So Long?
You might be curious about how one can have bone cancer for such a long period without knowing. The main
reason is that identifying bone cancer in its initial stage is difficult since a person will not show any major signs or
symptoms of having it. And unless the person goes to a doctor and undergoes multiple tests, identifying it with
only visual inspections becomes very difficult.
Since bone cancer starts in the bones, it’s impossible to know about it through the naked eye. For that reason,
bone cancer in a person can go undetected for five years and even more in a few cases. This long delay can lead
to difficulty providing treatment and diagnosing the person’s exact condition.
As bone cancer shows no major symptoms, you need to take the help of doctors who have the right tools to
diagnose your hidden cancer and other health conditions. They use tests like CT scans, X-rays, and MRIs to
diagnose a patient’s condition.
So, a person may not realize they have bone cancer unless they enter the critical stage. And thus, this increases
the importance of regular screenings in individuals. So, how will you know whether you have bone cancer? For
that, you must be aware of bone cancer signs and symptoms, which we will discuss now.
7. Common Signs And Symptoms Of Bone Cancer
Here are some of the common symptoms and signs of bone cancer:
•a feeling of pain and unexpected swelling in the affected bones area
•a noticeable hard mass in the long bones of a person’s chest, limbs, or pelvis
•an extra feeling of fatigue and tiredness
•extreme pain in bones, especially at night
•less flexibility and increased difficulty while moving
•bone pain due to minor trauma
Some less common symptoms of bone cancer include:
•fever
•unexpected weight loss
•easy broken bone injuries
8. What Are The Causes Of Bone Cancer?
•Atypical Cellular Growth
If you are familiar with the term cell, you may know that our body has millions of them. In these cells, there are both
healthy and unhealthy old cells. Our body continuously produces new healthy cells, which later on divide to take the place
of older cells. In this process of replacing, the older cells die. But cells like atypical cells don’t get eliminated in the process
and are called abnormal cells for that reason. These cells don’t necessarily cause cancer, but if a large mass of tissue is
formed, it can lead to tumors.
•Chromosomal Mutations
Genetic or chromosomal mutations are one of the causes which can increase the chances of bone cancer, and it might be
inherited. However, such cases are rare, and you will likely not develop bone cancer. Also, radiation can be a cause of
mutations, but there isn’t any particular cause of it.
•Radiation Therapy
You may have heard of radiation therapy, which is highly popular for killing cancer cells. This treatment is also quite
effective for treating bone cancer.
However, there are chances that people might develop Osteosarcoma after taking radiation therapy. This mostly happens
when there is the use of large doses of radiation.
9. What Are The Risk Factors For Bone Tumor or Cancer?
So, now you know the potential causes that might lead to bone cancer. Now, let’s get familiarized with the risk factors for
bone cancer.
This includes:
•a history of bone cancer or any other cancer in the family
•case of receiving radiation therapy or treatment in the past
•history of Paget disease that causes the growth of bones atypically
•a part of having multiple tumors in the cartilage
•having Rothmund-Thomson syndrome, Li-Fraumeni syndrome, or Bloom syndrome, increasing the risk of cancer
development.
10. Staging And Diagnosing Bone Cancer
Primary bone cancer is classified into different stages. The cancer stage tells the cancer position, progress rate, and effect
on other body parts.
•Stage 1: The bone tumor is localized and still low-grade.
•Stage 2: The tumor is high-grade but still localized.
•Stage 3: The cancer is high-grade and has spread to areas within the bone.
•Stage 4: The tumor had spread from one bone to other body areas, like the liver or lungs.
The doctor can use various methods to diagnose the cancer stage in the bones, including:
•Biopsy: It involves analyzing a small tissue sample in order to diagnose cancer
•Bone scan: Basically involves diagnosing the bones condition
•Blood test: Used to establish a baseline that can be used during treatment
•Imaging test: Use of CT scan, X-rays, MRI, and PET, to know a defined structure of the bones
11. How Can You Treat Bone Cancer?
•Surgery: This treatment involves removing affected tissue as well as tumors surgically. Surgery also involves removing
and replacing the affected bone, which can stop cancer growth from spreading rapidly. However, this type of surgery is
only used when you think you are ready for it or if that’s the only way to save you from cancer. You may need
amputation if there is high bone damage in the legs or arms.
•Radiation therapy: This treatment involves high doses of X-rays that help shrink and eliminate tumors. Many doctors will
use radiation therapy before surgery to reduce the tumor size, so there is no need to remove large tissue, and only less
tissue is needed to be removed.
•Chemotherapy: This treatment involves using medicines to kill every cancer cell in the body. The usual way to take anti-
cancer medicines consists of swallowing pills or injecting them into your body through a vein. Doctors can use
medication to treat both secondary and primary bone cancers.
12. Is Bone Cancer Fatal? What’s The Survival Rate Of Bone Cancer?
The answer is not usually when we talk about whether bone cancer is fatal. Of course, there are cases where people die
of bone cancer. However, in most cases, a person can make a full recovery from bone cancer. The five-year survival rate
for bone tumors is around 66.8%. This implies that 66.8% of the population survived bone cancer even after five years of
their diagnosis.
Make sure you remember that this survival rate is based on people who have survived bone cancer in the past. Don’t
make it a standard for how long you will live since it can vary from person to person. You must consult your health
provider to learn bone cancer survival rates in your case.
Most people will be able to survive bone cancer by undergoing treatment. People in the early stage of bone cancer have
more chances to go through full recovery. In the later stages of bone cancer, the survival rate decreases drastically.
13. Conclusion
Bone cancer is uncommon, and a person’s chances of developing primary bone cancer are few. Your survival rate will
depend on the stage of your bone cancer, size, and the affected area. If bone cancer is detected early, the chances of
survival increase drastically. So, see if you have symptoms that can be signs of bone cancer in you. Meet your doctor to
know the best treatment plan for you.
University Cancer Centers help you find the best treatment plan for your cancer. We are a team of professional doctors
who diagnose your condition, learn about your medical history, and accordingly recommend the best treatment plan.
Radiation therapy may not work for every patient and can be even risky for many. Our healthcare providers see if the
treatment we recommend is actually good for you and safe.
Contact us at (713) 474-1414 to book an appointment with our professional healthcare providers to get a perfect
treatment plan for your bone cancer.