Biopharmaceuticals are pharmaceuticals produced through biotechnology methods using living organisms or their components. They include protein or nucleic acid based drugs. Biotechnology allows for large-scale production of substances like insulin for diabetes treatment. It also enables targeted treatments for specific diseases and patient groups. Some key biopharmaceuticals are insulin, interferons, blood clotting factors, and growth factors. However, proteins face stability issues due to their large size and structure. Various formulation and delivery methods can address these challenges, including addition of stabilizing agents, PEGylation, micelles, and permeabilizers to aid delivery.

1. Development of Biopharmaceuticals

5. Biopharmaceuticals history

12. How to Deal with These Problems Storage Delivery Formulation

13. How to Deal with These Problems Storage Delivery Formulation