BIOLOGY CHAPTER 6 &
7
  Meiosis and Mendelian Genetics
6.1 & 6.2 CHROMOSOMES AND
 MEIOSIS
 6.6 MEIOSIS AND GENETIC VARIATION
Mitosis
Somatic cells undergo mitosis
One diploid cell produces 2 genetically
 identical, diploid cells
There are 4 stages (prophase, metaphase,
 anaphase, telophase)
DNA is copied once and divided once
Mitosis is used for development, growth, and
 repair
Meiosis
Germ cells produce gametes (sex cells) during
 meiosis
One diploid cell produces 4 genetically
 different haploid cells
There are 8 stages (prophase I, metaphase I,
 anaphase I, telophase I, prophase II,
 metaphase II, anaphase II, telophase II)
DNA is copied once and divided twice
Homologous Chromosomes
Half of an organism’s chromosomes come from the
 mother, and half from the father. The chromosomes
 pair up to form homologous chromosomes
Homologous chromosomes are two chromosomes
 with the same length, general appearance, and the
 same type of genes
The pairing of the genes on the homologous
 chromosomes are what code for all of an organism’s
 traits (see examples in section 6.4)
All humans have 23 total pairs of
 chromosomes, for a total of 46 chromosomes.
22 of the pairs are autosomes (body
 chromosomes)
1 pair is the sex chromosomes (XX= female,
 XY=male)
Meiosis I
Same steps as mitosis, except during
 Prophase I crossing over can occur(see
 below),
during Metaphase I homologous chromosomes
 pair up in the middle and
during Anaphase I, the sister chromatids DO
 NOT separate
By the end of Meiosis I, there are 2 haploid
 cells
Crossing Over
Homologous chromosomes exchange genes
This results in a new combination of genes
 (called recombination)
Genes that are located near each other on a
 chromosome are more likely to be moved (or
 crossed over) together. This is called genetic
 linkage (refer to page 191)
Meiosis II
This is exactly the same as mitosis
6.3 MENDEL AND HEREDITY

Gregor Mendel
An Austrian monk who is known as the “father
 of genetics”
He discovered that traits (genes) are inherited
 from parents by working with pea plants
He made both purebred plants and crossed
 plants to see what the results would be.
WHY PEA PLANTS?
They reproduce quickly
They can both self-pollinate(creating
 purebreds) and cross-pollinate(creating a mix
 of traits)
They have “either-or” traits (the traits do not
 mix to make a 3rd trait, ex. The purple flowers
 and white flowers don’t mix to make a pink
 flower)
(refer to page 179 to see the traits and results
 of Mendel’s experiment)
MENDEL’S CONCLUSIONS
Mendel’s Law of Segregation:
 Organisms inherit two copies of each gene,
 one from each parent
Organisms donate only one copy of each gene
 in their gametes. Thus, the two copies of each
 gene segregate, or separate, during gamete
 formation (Law of Independent Assortment)
In other words, the Law of Ind. Assortment is
 saying that traits are inherited separately.
6.4 TRAITS, GENES, AND ALLELES
6.5 TRAITS AND PROBABILITIES

Genes
Each gene has a specific locus, or place on
 the chromosome
A gene is a piece of DNA that provides a set of
 instructions to make a certain protein. The
 proteins then code for traits.
Each trait is represented by alleles.
Letters are used to represent different alleles.
 There are two alleles per trait (one from
 mother, one from father)
Dominant alleles are represented by capital
 letters and Recessive alleles are represented
 by lowercase letters
Dominant alleles will always overpower the
 recessive alleles.
EXAMPLE: P= purple flowers
         p= white flowers

PP=purple flowers (homozygous)
pp= white flowers (homozygous)
Pp= purple flowers (heterozygous)

Genotype-the alleles/genetic code (PP or Pp)
Phenotype-the physical trait (purple or white)
PUNNET SQUARES

Punnet squares are used to predict the outcome of
 genotypes when crossing two organisms
Monohybrid cross- crosses one trait (always yields a
 3:1 phenotypic ratio)
Dihybrid cross- crosses two traits (always yield
 9:3:3:1 phenotypic ratio)
CHAPTER 7
EXTENDING MENDELIAN GENETICS

Complex Patterns of Inheritance
Incomplete Dominance—the trait is in between
the dominant and recessive
     Ex. RR=red rr=white   Rr=pink


Codominance—both traits are expressed at the
same time
     Ex. RR=red rr=white   Rr= both red and white
Polygenic Traits—when two or more
genes influence a trait
Ex. Human eye color(at least 3 different
 genes), human skin color (4 different genes)


Environmental factors—when the
environment plays a role in gene
expression
Ex. Sea turtle eggs become female in warmer
 temps and male in colder temps
SEX-LINKED TRAITS—TRAITS CAUSED
 BY GENES LOCATED ON THE SEX
 CHROMOSOMES
  The X contains many genes
  The Y only determines sex (male)
  A male is XY, so all of the alleles on the X are
    expressed in a male, even the recessive ones
  A female is XX, so dominant alleles can mask
    the recessive ones
Carriers—those who carry a recessive genetic
 disorder, but do not express the phenotype. They
 can pass on the disorder to their offspring

Biology chapter 6 & 7

  • 1.
    BIOLOGY CHAPTER 6& 7 Meiosis and Mendelian Genetics
  • 2.
    6.1 & 6.2CHROMOSOMES AND MEIOSIS 6.6 MEIOSIS AND GENETIC VARIATION Mitosis Somatic cells undergo mitosis One diploid cell produces 2 genetically identical, diploid cells There are 4 stages (prophase, metaphase, anaphase, telophase) DNA is copied once and divided once Mitosis is used for development, growth, and repair
  • 3.
    Meiosis Germ cells producegametes (sex cells) during meiosis One diploid cell produces 4 genetically different haploid cells There are 8 stages (prophase I, metaphase I, anaphase I, telophase I, prophase II, metaphase II, anaphase II, telophase II) DNA is copied once and divided twice
  • 4.
    Homologous Chromosomes Half ofan organism’s chromosomes come from the mother, and half from the father. The chromosomes pair up to form homologous chromosomes Homologous chromosomes are two chromosomes with the same length, general appearance, and the same type of genes The pairing of the genes on the homologous chromosomes are what code for all of an organism’s traits (see examples in section 6.4)
  • 5.
    All humans have23 total pairs of chromosomes, for a total of 46 chromosomes. 22 of the pairs are autosomes (body chromosomes) 1 pair is the sex chromosomes (XX= female, XY=male)
  • 6.
    Meiosis I Same stepsas mitosis, except during Prophase I crossing over can occur(see below), during Metaphase I homologous chromosomes pair up in the middle and during Anaphase I, the sister chromatids DO NOT separate By the end of Meiosis I, there are 2 haploid cells
  • 7.
    Crossing Over Homologous chromosomesexchange genes This results in a new combination of genes (called recombination) Genes that are located near each other on a chromosome are more likely to be moved (or crossed over) together. This is called genetic linkage (refer to page 191) Meiosis II This is exactly the same as mitosis
  • 8.
    6.3 MENDEL ANDHEREDITY Gregor Mendel An Austrian monk who is known as the “father of genetics” He discovered that traits (genes) are inherited from parents by working with pea plants He made both purebred plants and crossed plants to see what the results would be.
  • 9.
    WHY PEA PLANTS? Theyreproduce quickly They can both self-pollinate(creating purebreds) and cross-pollinate(creating a mix of traits) They have “either-or” traits (the traits do not mix to make a 3rd trait, ex. The purple flowers and white flowers don’t mix to make a pink flower) (refer to page 179 to see the traits and results of Mendel’s experiment)
  • 10.
    MENDEL’S CONCLUSIONS Mendel’s Lawof Segregation:  Organisms inherit two copies of each gene, one from each parent Organisms donate only one copy of each gene in their gametes. Thus, the two copies of each gene segregate, or separate, during gamete formation (Law of Independent Assortment) In other words, the Law of Ind. Assortment is saying that traits are inherited separately.
  • 11.
    6.4 TRAITS, GENES,AND ALLELES 6.5 TRAITS AND PROBABILITIES Genes Each gene has a specific locus, or place on the chromosome A gene is a piece of DNA that provides a set of instructions to make a certain protein. The proteins then code for traits. Each trait is represented by alleles.
  • 12.
    Letters are usedto represent different alleles. There are two alleles per trait (one from mother, one from father) Dominant alleles are represented by capital letters and Recessive alleles are represented by lowercase letters Dominant alleles will always overpower the recessive alleles.
  • 13.
    EXAMPLE: P= purpleflowers p= white flowers PP=purple flowers (homozygous) pp= white flowers (homozygous) Pp= purple flowers (heterozygous) Genotype-the alleles/genetic code (PP or Pp) Phenotype-the physical trait (purple or white)
  • 14.
    PUNNET SQUARES Punnet squaresare used to predict the outcome of genotypes when crossing two organisms Monohybrid cross- crosses one trait (always yields a 3:1 phenotypic ratio) Dihybrid cross- crosses two traits (always yield 9:3:3:1 phenotypic ratio)
  • 15.
    CHAPTER 7 EXTENDING MENDELIANGENETICS Complex Patterns of Inheritance Incomplete Dominance—the trait is in between the dominant and recessive Ex. RR=red rr=white Rr=pink Codominance—both traits are expressed at the same time Ex. RR=red rr=white Rr= both red and white
  • 16.
    Polygenic Traits—when twoor more genes influence a trait Ex. Human eye color(at least 3 different genes), human skin color (4 different genes) Environmental factors—when the environment plays a role in gene expression Ex. Sea turtle eggs become female in warmer temps and male in colder temps
  • 17.
    SEX-LINKED TRAITS—TRAITS CAUSED BY GENES LOCATED ON THE SEX CHROMOSOMES The X contains many genes The Y only determines sex (male) A male is XY, so all of the alleles on the X are expressed in a male, even the recessive ones A female is XX, so dominant alleles can mask the recessive ones Carriers—those who carry a recessive genetic disorder, but do not express the phenotype. They can pass on the disorder to their offspring