Physical cause
Brain Differences –
                  Structure (e.g. size)
           Function (e.g. biochemical balance)

Genetics – Genetic component - inherited
              Passed through family lines



    Uses twin studies to investigate
If the biological approach believes that all
abnormalities have a biological component – what
treatments do you think the approach would use
               to treat disorders?
  (Or, what would the treatments focus on ?)




             Treating the BODY!!!
• Drug treatments:
  – Anti-depressants (selective serotonin
    reuptake inhibitors)
  – Anti-anxiety drugs (benzodiazepines)



• ECT: (Electro-Convulsive Therapy)
• What are they used for?
   – To treat depression
   – To treat agoraphobia and social phobia

• How do they work?
  - Raise levels of serotonin in the brain
  - Prozac reduces the rate of re-absorption of serotonin (serotonin
    levels don’t drop, mood remains constant).
  - Prozac can be a long term treatment (also used to treat OCD)


• Are there any side effects?
   –   Nausea,
   –   Insomnia
   –   Sexual dysfunction
   –   Suicidal morbidity
• What are they used for?
   – Range of anxiety disorders (phobias, panic attacks and sleep
     disorders)
   – Extreme, prolonged stress.

• How do they work?
  - GABA has a natural ‘quietening’ effect on neurons in the
    brain. GABA activity is enhanced by the drugs (reduces
    serotonin)
  - Sedatives that act to decrease heart and respiration rate
    (reduce tension and nervousness)
  - Calming effect

• Are there any side effects?
   • Dependency (addiction)
   • Drowsiness and lethargy
   • Toxic – overdose can lead to death
Effective

             Drug therapies are effective




e.g. Kahn (1986) found that biological therapies (drugs)
        were much more effective than placebos


This is a strength because it means that individuals are
 being relieved of symptoms, helping them cope with
                     everyday life
Side effects

          Drugs can have negative side effects




  e.g. anti-depressants can cause suicidal morbidity and
                         insomnia



This is a weakness because drug therapies might make the
                 patient’s condition worse
Symptoms not cause?
Drug therapies often only treat the symptoms rather than
                 the cause of a disorder



 e.g. depression could be caused by family issues rather
               than low levels of serotonin


  This is a weakness because drugs don’t provide a long-
term solution and the effects of the drugs stop when the
                        drugs do
Used for drug resistant depression
           Last resort (NICE 2003)
•Small electric current passed through the brain
•(70 - 150 volts for 0.04 - 1 second)
• Causes a seizure, lasts for up to 1 minute (similar to
epilepsy)
• General anaesthetic & muscle relaxants
•Brain stimulated by placing electrodes on
head
• Bilateral (both sides) or Unilateral (one side, non-
dominant hemisphere)
•Process repeated 3 times a week for up to a month.
• Biochemical change:
  – Produces biochemical changes (greater than
    drugs)
  – Increased sensitivity to serotonin
  – Increases release of dopamine (Sasa, 1999)



• Brain damage theory:
  – Produces brain damage, memory loss,
    disorientation – creates the illusion that
    problems have gone.
Abrams (1997)
after 50 years
 we still don’t
    know!!
For example, Comer (2002) found that 60-70% of
patients improve after treatment.




 This is a strength because is suggests that ECT is a
useful therapy where all others have failed and when the
 depression is so severe that it could otherwise lead to
                         suicide.
For example, the DOH (1999) reported that in 30% of
cases patients reported permanent anxiety/fear.




   This is a weakness because ECT can cause serious
damage and might actually be doing more harm than good,
and patients should be fully aware of all potential harmful
                      side effects.
For example, ECT can be given under section III of the
MHA (1983) – against the patients wishes.




This is a weakness because in a large number of patients
   there is a real risk of long-term brain impairment –
 patients that may not have had a choice to decline the
                         treatment.

Biological therapies

  • 2.
    Physical cause Brain Differences– Structure (e.g. size) Function (e.g. biochemical balance) Genetics – Genetic component - inherited Passed through family lines Uses twin studies to investigate
  • 3.
    If the biologicalapproach believes that all abnormalities have a biological component – what treatments do you think the approach would use to treat disorders? (Or, what would the treatments focus on ?) Treating the BODY!!!
  • 4.
    • Drug treatments: – Anti-depressants (selective serotonin reuptake inhibitors) – Anti-anxiety drugs (benzodiazepines) • ECT: (Electro-Convulsive Therapy)
  • 5.
    • What arethey used for? – To treat depression – To treat agoraphobia and social phobia • How do they work? - Raise levels of serotonin in the brain - Prozac reduces the rate of re-absorption of serotonin (serotonin levels don’t drop, mood remains constant). - Prozac can be a long term treatment (also used to treat OCD) • Are there any side effects? – Nausea, – Insomnia – Sexual dysfunction – Suicidal morbidity
  • 6.
    • What arethey used for? – Range of anxiety disorders (phobias, panic attacks and sleep disorders) – Extreme, prolonged stress. • How do they work? - GABA has a natural ‘quietening’ effect on neurons in the brain. GABA activity is enhanced by the drugs (reduces serotonin) - Sedatives that act to decrease heart and respiration rate (reduce tension and nervousness) - Calming effect • Are there any side effects? • Dependency (addiction) • Drowsiness and lethargy • Toxic – overdose can lead to death
  • 7.
    Effective Drug therapies are effective e.g. Kahn (1986) found that biological therapies (drugs) were much more effective than placebos This is a strength because it means that individuals are being relieved of symptoms, helping them cope with everyday life
  • 8.
    Side effects Drugs can have negative side effects e.g. anti-depressants can cause suicidal morbidity and insomnia This is a weakness because drug therapies might make the patient’s condition worse
  • 9.
    Symptoms not cause? Drugtherapies often only treat the symptoms rather than the cause of a disorder e.g. depression could be caused by family issues rather than low levels of serotonin This is a weakness because drugs don’t provide a long- term solution and the effects of the drugs stop when the drugs do
  • 10.
    Used for drugresistant depression Last resort (NICE 2003) •Small electric current passed through the brain •(70 - 150 volts for 0.04 - 1 second) • Causes a seizure, lasts for up to 1 minute (similar to epilepsy) • General anaesthetic & muscle relaxants •Brain stimulated by placing electrodes on head • Bilateral (both sides) or Unilateral (one side, non- dominant hemisphere) •Process repeated 3 times a week for up to a month.
  • 11.
    • Biochemical change: – Produces biochemical changes (greater than drugs) – Increased sensitivity to serotonin – Increases release of dopamine (Sasa, 1999) • Brain damage theory: – Produces brain damage, memory loss, disorientation – creates the illusion that problems have gone.
  • 12.
    Abrams (1997) after 50years we still don’t know!!
  • 13.
    For example, Comer(2002) found that 60-70% of patients improve after treatment. This is a strength because is suggests that ECT is a useful therapy where all others have failed and when the depression is so severe that it could otherwise lead to suicide.
  • 14.
    For example, theDOH (1999) reported that in 30% of cases patients reported permanent anxiety/fear. This is a weakness because ECT can cause serious damage and might actually be doing more harm than good, and patients should be fully aware of all potential harmful side effects.
  • 15.
    For example, ECTcan be given under section III of the MHA (1983) – against the patients wishes. This is a weakness because in a large number of patients there is a real risk of long-term brain impairment – patients that may not have had a choice to decline the treatment.