Bed Bug Control With IGR Insect Growth Regulators Juvenile Hormones and chitin synthesis inhibitor. What works, what doesn't work and what shows promise. http://www.pestgeekpodcast.com/bed-bug/bed-bug-control-with-igr-insect-growth-regulators

1. By Franklin Hernandez
Bed Bug Control With IGR Insect Growth Regulators
www.pestgeekpodcast.com/bed-bug/bed-bug-control-with-igr-insect-growth-regulators/
Bed Bug Control With IGR Insect Growth Regulators Juvenile
Hormones and chitin synthesis inhibitor.
What works, what dosnt work and what shows promise.
Krüppel homolog 1 and E93 mediate Juvenile hormone methoprene regulation of
metamorphosis in the common bed bug, Cimex lectularius
We studied the regulation of molting and metamorphosis in bed bugs with a goal to identify
key players involved.
Methoprene induced Kr-h1 and suppressed E93 and induced formation of the supernumerary
nymph.
These data show interactions between Kr-h1, E93 and JH in the regulation of metamorphosis
in the bed bugs.
https://www.nature.com/articles/srep26092?WT.feed_name=subjects_zoology
The Occurrence of the Holometabolous Pupal Stage Requires the Interaction
between E93, Krüppel-Homolog 1 and Broad-Complex
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006020
Efficacy of (S)-methoprene against Cimex lectularius (Hemiptera: Cimicidae).
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2. A dose of 30 mg/m2 has been shown to interrupt the development of susceptible bed bugs in
laboratory experiments. The efficacy of (S)-methoprene was assessed against both a
laboratory susceptible strain and a field strain resistant to pyrethroid and carbamate
insecticides.
https://www.cabdirect.org/cabdirect/abstract/20133307487
Effects of juvenile hormone analog formulations on development and reproduction
in the bed bug Cimex lectularius (Hemiptera: Cimicidae)
RESULTS: At 1× and 2× the label rate, Precor® [active ingredient (S)-methoprene] had no
significant effect on the development or the ability to produce an abundance of offspring or
new growth; of bed bugs. At 2× the label rate, confinement to residues of Gentrol® [active
ingredient (S)-hydroprene] had no significant effect, but residues at 3× and 10× the label rate
caused a reduction in fecundity and impaired development.
http://onlinelibrary.wiley.com/doi/10.1002/ps.3376/full
Locomotion Inhibition of Cimex lectularius L. Following Topical, Sublethal Dose
Application of the Chitin Synthesis Inhibitor Lufenuron.
The chitin synthesis inhibitor lufenuron had a significant effect on the ecdysis of fifth instar
bed bugs to adult. The effective dose that resulted in 50% malformations and mortality
(ED50)
There is no product labeled for bed bug use it’s the active ingredient in the dog chew in the
veterinary flea control medication.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620714/
Juvenile hormone regulation of female reproduction in the common bed bug,
Cimex lectularius
To begin studies on reproduction in common bed bug we identified 3 genes coding for a
protein required for the reproductive success of insects and studied their hormonal regulation.
https://www.nature.com/articles/srep35546?WT.feed_name=subjects_rnai
Genome assembly and geospatial phylogenomics of the bed bug Cimex
lectularius
https://www.nature.com/articles/ncomms10164?WT.ec_id=NCOMMS-20160203&message-
global=remove&spJobID=860336606&spMailingID=50613647&spReportId=ODYwMzM2NjA2S
0&spUserID=ODkwMTM2NjQyNgS2
Development of multifunctional metabolic synergists to suppress the evolution of
resistance against pyrethroids in insects that blood feed on humans 3-
Phenoxybenzyl hexanoate (PBH) was synthesized as a multifunctional pyrethroid
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3. synergist.
The addition of PBH to permethrin-treated females of the ISOP450 strain of Culex pipiens
quinquefasciatus resulted in a threefold increase in synergism, as judged by the synergistic
ratio. Similarly, PBH synergized the action of deltamethrin sixfold on females of the common
bed bug, Cimex lectularius, and was 2.8-fold more synergistic than piperonyl butoxide (PBO).
http://onlinelibrary.wiley.com/doi/10.1002/ps.3856/full
Steri-Fab Insecticide
Bedlam Plus Aerosol
NyGuard Plus
Bedlam Insecticide Aerosol
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