The document provides summaries and analyses of four music videos:
1) Krewella - Broken Record uses imagery that corresponds to the lyrics and changes with the beat. Shots include friends to represent different sides and blurred motion to create suspense.
2) Lucas Graham - 7 Years Old uses symbolism to represent events from the artist's life and growing up. Shots include friends and a book representing years passing.
3) The video for Lucas Graham's song is filmed in black and white to create a dramatic look and has been viewed over 500 million times, helping people recognize the artist.
4) Sia - Chandelier features a girl dancing in mysterious movements in a run-down, abandoned
micro teaching on communication m.sc nursing.pdfAnurag Sharma
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A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Krewella - Broken record
EDM/Dance-pop
In this music video you see a lot of different imagery which is directed to the lyrics, and
progress along with the beat
The imagery and
different shot types
promote her
personal look as an
artist
Many of the shots,
include her friend. I
believe she
represents her
different yet similar
sides
There are some
blurred out motion
shots to create
more suspense, and
tense atmosphere
This shot shows that she
had a very emotional
bond with the person she
sings about
“Some things are permanent, like the ink
that’s on my skin” Imagery directly reflecting
the lyrics. Also means that the tattoos oh him
are permanent, unlike their relationship
Various shots are in
different colour,
which represent her
emotions
3. Krewella - Broken record
EDM/Dance-pop
Whenever the beat
drops, the shots
become somewhat
blurry, and have
lines outlining
motion The outlines makes
the video more
powerful without
using a large variety
of different shots
These shots help her
promote her own style,
as it is linked directly to
her music
4. Lucas Graham - 7 Years old
Pop/Soul
Lucas Graham shows his
own style by showing a lot
of symbolism which
represent different events
in his life.
Many of the things which
are shown in his videos
represent his childhood
and the way he grew up.
This song is about his life,
and him sitting in the
cinema suggest that he is
watching his life
These are the people he refers to
as friend in his song. The reason
they are in this video is to
represent their unspoken bond
The book in this shot represents
his years flying by
In this shot we see
him ripping a page out
of his book with lyrics,
suggesting that he
started a new page in
his life with music
5. Lucas Graham - 7 Years old
Pop/Soul
The video is shot in B&W creating
a more dramatic look to this music
video
This look promotes him as
an artist, and as the video
has over 500 million views
people will be able to
recognise him
The video was shot in low
budget, making his look
appear more authentic
6. Sia – Chandelier
Pop
The wig represents Sia
not wanting to be
seen in public
In the music video, the
girl dances and makes
some mystic moves
which seem very
strange and weird.
Many mysterious
movements are
shown to further
imply Sias mystery as
an artist.
The performance
appearance is almost
doll like, which helps to
create Sia’s own style
End with an open
ending, making the
viewer wonder what
happens after. Further
crating her mysterious
appearance.
The place where the
girl is located is run
down, and looks
abandoned
