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Young age
Middle age
40 - 50
Thick congenital bicuspid
Rarely
• Unicuspid
• Supravalvular
• subvalvular
• Thick degenerative valve
• Calcified congenital biscuspid
valve
• Rheumatic fever
Old age
60 - 80
• Thick bicuspid valve
• Rheumatic disease
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Valvular Subvalvular Supravalvular
Rheumatic fever
Degenerative
Biscuspid
Subaortic membrane
HOCM
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AS
Pressure
overload
of LV
LVESP > Ao.
Systolic pressure
LV
hypertrophy
Reduced LV compliance
leads to diastolic
dysfunction and
increased LVEDP
Increased myocardial
oxygen requirement
Reduced coronary
blood flow leads to
angina
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AS is a progressive disease and patients remains asymptomatic for years
Symptoms
Angina Syncope Dyspnoea
++ O2
demand
++ LVEDP
-- CO due to
LVOT
++ LVEDP
and LAP with
pulmonary
congestion
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Pulsus
Tardus (slow rising
pulse)
Parvus (small amplitude
pulse)
Sustained
Apical impulse
Due to
prolonged left
ventricular
ejection
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Heart Sound
Valvular AS Other causes
S2
diminished
or absent
Single or
split
Ejection click
no
calcification
4th sound
(Apex)
Normal S2
in HOCM
++ S2 in
cong.
Valvular AS
Ejection click
absent
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Murmur
Valvular AS
Max. intensity: A1
Propagation :root of the neck, Apex, carotid
HOCM—A2
Tri leflet AS – Apex (Gallaverdin
sign)
Supravalvular – Rt infraclavicular
Mid to late systolic
Thrill: A1
Short and peaks earlier
Character: Harsh
Contour: Crescendo -
decrescendo
Soft if functional
Musical if pliable and calcific
Timing: Midsystolic
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Mild Moderate Severe
Aortic valve area (cm2) 1.5 – 2.5 1.0 – 1.5 <1.0
Mean pressure gradient (mmHg) 15 - 25 25 - 40 > 40
Peak Velocity (m/s) < 3.0 3 – 4 >4
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Severe
> 40 mmHg
Moderate
20 – 40 mmHg
Symptomatic
Class IIAClass IIBClass IIAClass I
Asymptomatic Symptomatic Asymptomatic
LVEF < 50 %
Other cardiac surgery
> 60 mmHg
Abnormal ETT
∆ in velocity > 0.3 m/s/y
And other cardiac
operations
LVEF < 50 %
Yes No
DSE
Ao. Valve area <
1cm2
Ao. Flow > 4 m/s
AVA < 1cm2
&
LVEF > 50 %
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Aortic valve stenosis

  • 1.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved
  • 2.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Young age Middle age 40 - 50 Thick congenital bicuspid Rarely • Unicuspid • Supravalvular • subvalvular • Thick degenerative valve • Calcified congenital biscuspid valve • Rheumatic fever Old age 60 - 80 • Thick bicuspid valve • Rheumatic disease
  • 3.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Valvular Subvalvular Supravalvular Rheumatic fever Degenerative Biscuspid Subaortic membrane HOCM
  • 4.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved AS Pressure overload of LV LVESP > Ao. Systolic pressure LV hypertrophy Reduced LV compliance leads to diastolic dysfunction and increased LVEDP Increased myocardial oxygen requirement Reduced coronary blood flow leads to angina
  • 5.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved AS is a progressive disease and patients remains asymptomatic for years Symptoms Angina Syncope Dyspnoea ++ O2 demand ++ LVEDP -- CO due to LVOT ++ LVEDP and LAP with pulmonary congestion
  • 6.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Pulsus Tardus (slow rising pulse) Parvus (small amplitude pulse) Sustained Apical impulse Due to prolonged left ventricular ejection
  • 7.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Heart Sound Valvular AS Other causes S2 diminished or absent Single or split Ejection click no calcification 4th sound (Apex) Normal S2 in HOCM ++ S2 in cong. Valvular AS Ejection click absent
  • 8.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Murmur Valvular AS Max. intensity: A1 Propagation :root of the neck, Apex, carotid HOCM—A2 Tri leflet AS – Apex (Gallaverdin sign) Supravalvular – Rt infraclavicular Mid to late systolic Thrill: A1 Short and peaks earlier Character: Harsh Contour: Crescendo - decrescendo Soft if functional Musical if pliable and calcific Timing: Midsystolic
  • 9.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Mild Moderate Severe Aortic valve area (cm2) 1.5 – 2.5 1.0 – 1.5 <1.0 Mean pressure gradient (mmHg) 15 - 25 25 - 40 > 40 Peak Velocity (m/s) < 3.0 3 – 4 >4
  • 10.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved Severe > 40 mmHg Moderate 20 – 40 mmHg Symptomatic Class IIAClass IIBClass IIAClass I Asymptomatic Symptomatic Asymptomatic LVEF < 50 % Other cardiac surgery > 60 mmHg Abnormal ETT ∆ in velocity > 0.3 m/s/y And other cardiac operations LVEF < 50 % Yes No DSE Ao. Valve area < 1cm2 Ao. Flow > 4 m/s AVA < 1cm2 & LVEF > 50 %
  • 11.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved
  • 12.
    T&M Medical SoftwareSolutions, Inc. All Rights Reserved
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    T&M Medical SoftwareSolutions, Inc. All Rights Reserved
  • 14.
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