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Nizar Muhammad (Pharm-D)
Ayub Medical Complex, Abbottabad, Pakistan
nizarmuhammad432@gmail.com 1
Pancreatic Hormones
• In the endocrine pancreas, the islets of
Langerhans contain at least 4 types of
endocrine cells including:
1. A (alpha, glucagon producing),
2. B (beta, insulin, and amylin producing),
3. D (delta, somatostatin producing),
4. F (pancreatic polypeptide producing).
• Of these, the B (insulin-producing) cells are
the most numerous.
nizarmuhammad432@gmail.com 2
You may know
• The most common pancreatic disease requiring
pharmacologic therapy is diabetes mellitus, a
deficiency of insulin production or effect.
• Diabetes is treated with several parenteral
formulations of insulin and oral or parenteral
noninsulin antidiabetic agents.
• Glucagon, a hormone that affects the liver,
cardiovascular system, and gastrointestinal tract,
can be used to treat severe hypoglycemia.
nizarmuhammad432@gmail.com 3

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antidiabetic drugs.pptx

  • 1. Nizar Muhammad (Pharm-D) Ayub Medical Complex, Abbottabad, Pakistan nizarmuhammad432@gmail.com 1
  • 2. Pancreatic Hormones • In the endocrine pancreas, the islets of Langerhans contain at least 4 types of endocrine cells including: 1. A (alpha, glucagon producing), 2. B (beta, insulin, and amylin producing), 3. D (delta, somatostatin producing), 4. F (pancreatic polypeptide producing). • Of these, the B (insulin-producing) cells are the most numerous. nizarmuhammad432@gmail.com 2
  • 3. You may know • The most common pancreatic disease requiring pharmacologic therapy is diabetes mellitus, a deficiency of insulin production or effect. • Diabetes is treated with several parenteral formulations of insulin and oral or parenteral noninsulin antidiabetic agents. • Glucagon, a hormone that affects the liver, cardiovascular system, and gastrointestinal tract, can be used to treat severe hypoglycemia. nizarmuhammad432@gmail.com 3