Antibiotics are often inappropriately prescribed by doctors to treat acne in India, despite evidence that they can worsen acne by creating antibiotic resistance. Specifically, the antibiotic azithromycin is not approved for treating acne but is commonly prescribed, leading to unnecessary development of resistance. Additionally, antibiotic use for acne is associated with higher risk of respiratory infections. Experts are concerned about the growing issue of antibiotic resistance in India due to overprescription and over-the-counter access to powerful antibiotics without proper oversight.

1. Antibiotics may make acne worse
Doctors Should Avoid Prescribing
Them As They Create Resistance To
Condition
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2. Contd..
• Use of antibiotics to treat acne can have serious consequences, new
research suggests.In India, dermatologists often prescribe
antibiotics of all sorts to treat skin diseases. High-end antibiotics
like azithromycin (normally used to treat sore throat and respiratory
infections) are also used. This, however, proves counterproductive,
say experts, as a microorganism develops resistance to the drugs.
• “Azithromycin is only approved for upper respiratory tract infection.
Its use for acne is not recommended anywhere in the world and is
totally off-label. But many dermatologists prescribe it to patients
for quicker results, thus creating a resist ance out of nothing,“ said
Dr Kabir Sardana, skin specialist at Maulana Azad Medical College.
He said research has revealed that oral antibiotics exert selective
pressure for resistance development at sites where there is normal
microflora.
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3. Contd..
• “In addition, the risk of an upper respiratory tract infection in
individuals who use an antibiotic to treat acne has been shown to
be about two-times higher than in those not using antibiotics,“ Dr
Sardana added.
• According to Dr Anoop Misra, chairman, Fortis CDoc Centre for
Diabetes, Obesity , Metabolic Diseases and Endocrinology , drug-
resistance is common in bacteria causing diseases like typhoid,
pneumonia, wound infections, urinary tract infections, septicaemia
and ab scesses. “There is no government control on sale and
purchase of even high-end antibiotics. People buy them over-the-
counter for common fever or diarrhoea without prescription,“ he
said, adding that many private practitioners prescribe higher
antibiotics unnecessarily , disregarding its adverse consequences.
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4. Contd..
• Health experts say no new groups of
antibiotics have been developed
since the 1990s. “Carbapenem is the
last group of antibiotics developed
worldwide. After that there have
been modifications to the available
drugs. On the other hand, there is
increase in drug-resistant
microorganisms.New Delhi Metallo-
B-Lactamose 1 (NDM1) is just one of
the examples,“ said Dr Misra.
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