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ANATOMY OF PENIS
&
PHYSIOLOGY OF ERECTION
Dr. Deepesh Kalra
Institute Of Urology
MMC
Composed of 3 cylindrical
structures.
Covered by loose SC tissue
and skin.
Flaccid state is maintained
by contractile state of
smooth muscles.
Penile component & their function during erection
 Corpora cavernosa – supports spongiosum & glans
 Tunuica albugenia – provides rigidity
Paticipates in veno-occlusion
 Smooth muscle – regulates blood flow into sinusoids
 Ischio-cavernosus – pumps blood distally
Provides additional rigidity
 Bulbo-cavernosus – compresses the bulb to expel semen
 Spongiosum – constricts urethra to expel semen
Common penile artery
Dorsal
Cavernosal
bulbourethral
Arterial Supply
Venous drainage
Mechanism of Erection
 CORPORA CAVERNOSA
• Flaccid state – smooth muscles are tonically contracted allowing only a
small portion of arterial flow into corpora.
 Sexual stimulation -
 Release of certain neurotransmitter -
 Relaxation of smooth muscles -
 Dilatation of arteriole -
 Increased blood flow
 Trapping of incoming blood by expanding sinusoids
 Compression of subtunical venous plexux by tunica
 contraction of ischio cavernosus
 Erection requires
 Sinusoidal relaxation
 Arteriole dilatation
 Venous compression
 CORPORA SPONGIOSUM -
• Thin tunical covering
• Less venous occlusion
• Less pressure increase
Despite the same increase in arterial flow
Neurophysiology
 Autonomic- Pelvic plexus
Sympathetic-T11-L2 - tumescence & ejaculation
Parasympathetic-S2-4 - erection
 Somatic
Ad and C fibres- sensation
Onuf nucleus-S2-4 ---Ischio-cavernosus- rigid erection
---- Bulbo-spongiosus - expulsion
Central control
 Right insula/inferior frontal cortex- increased activity during visually
evoked sexual stimulation
 Medial amygdala-sexual motivation
Ø Pyriform cortex - inhibits sexual drive
 Hippocampus—facilitates erection
Ø Hypothalamus -
MPOA- recognition of sexual partner ,integration of sensory &
hormonal cues.
PVN – facilitates erection
 Nucleus paragigantocellularis – inhibits erection
 ORGASM: mesodiencephalic transition zone
• Psychogenic— fantasy or audio-visual stimuli(Brain modulates the spinal
centre)
• Reflexogenic- Tactile stimulation( preserved in UMN)
• Nocturnal—REM sleep activity in Pontine reticulate formation
Peripheral neurotransmitters
FLACCIDITY ERECTION
NE NO
Endothelin Ach
PGI2,F2a CO
TXA2 EDGF
ATII
Central neurotransmitters
Increases sexual function Decrease sexual function
dopamine serotonin
NE opiods
Oxytocin GABA
NO prolactin
Melanocortin cannabinoids
NOS
• n NOS –Inititiation
• E NOS-Maintainence
• L arginine and molecular oxygen
NOS NOS
Molecular oxygen castration
androgen denervation
L arginine DM
Injection of PGE 1 hypercholesterolemia
Anatomy of penis & physiology of erection
Anatomy of penis & physiology of erection
Anatomy of penis & physiology of erection
Anatomy of penis & physiology of erection

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Anatomy of penis & physiology of erection

  • 1. ANATOMY OF PENIS & PHYSIOLOGY OF ERECTION Dr. Deepesh Kalra Institute Of Urology MMC
  • 2. Composed of 3 cylindrical structures. Covered by loose SC tissue and skin. Flaccid state is maintained by contractile state of smooth muscles.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Penile component & their function during erection  Corpora cavernosa – supports spongiosum & glans  Tunuica albugenia – provides rigidity Paticipates in veno-occlusion  Smooth muscle – regulates blood flow into sinusoids  Ischio-cavernosus – pumps blood distally Provides additional rigidity  Bulbo-cavernosus – compresses the bulb to expel semen  Spongiosum – constricts urethra to expel semen
  • 10.
  • 11.
  • 12. Mechanism of Erection  CORPORA CAVERNOSA • Flaccid state – smooth muscles are tonically contracted allowing only a small portion of arterial flow into corpora.  Sexual stimulation -  Release of certain neurotransmitter -  Relaxation of smooth muscles -  Dilatation of arteriole -  Increased blood flow  Trapping of incoming blood by expanding sinusoids  Compression of subtunical venous plexux by tunica  contraction of ischio cavernosus
  • 13.  Erection requires  Sinusoidal relaxation  Arteriole dilatation  Venous compression
  • 14.  CORPORA SPONGIOSUM - • Thin tunical covering • Less venous occlusion • Less pressure increase Despite the same increase in arterial flow
  • 15. Neurophysiology  Autonomic- Pelvic plexus Sympathetic-T11-L2 - tumescence & ejaculation Parasympathetic-S2-4 - erection  Somatic Ad and C fibres- sensation Onuf nucleus-S2-4 ---Ischio-cavernosus- rigid erection ---- Bulbo-spongiosus - expulsion
  • 16.
  • 17. Central control  Right insula/inferior frontal cortex- increased activity during visually evoked sexual stimulation  Medial amygdala-sexual motivation Ø Pyriform cortex - inhibits sexual drive  Hippocampus—facilitates erection Ø Hypothalamus - MPOA- recognition of sexual partner ,integration of sensory & hormonal cues. PVN – facilitates erection  Nucleus paragigantocellularis – inhibits erection  ORGASM: mesodiencephalic transition zone
  • 18. • Psychogenic— fantasy or audio-visual stimuli(Brain modulates the spinal centre) • Reflexogenic- Tactile stimulation( preserved in UMN) • Nocturnal—REM sleep activity in Pontine reticulate formation
  • 19. Peripheral neurotransmitters FLACCIDITY ERECTION NE NO Endothelin Ach PGI2,F2a CO TXA2 EDGF ATII
  • 20. Central neurotransmitters Increases sexual function Decrease sexual function dopamine serotonin NE opiods Oxytocin GABA NO prolactin Melanocortin cannabinoids
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28. NOS • n NOS –Inititiation • E NOS-Maintainence • L arginine and molecular oxygen NOS NOS Molecular oxygen castration androgen denervation L arginine DM Injection of PGE 1 hypercholesterolemia