The document discusses amputations as a result of war and their psychological and physical impacts. It covers causes of amputations like bombs and diseases, how surgeons determine if amputation is necessary, the surgical process, healing types, psychological effects including embarrassment and PTSD, advances in prosthetics allowing personality expression, and how a person's support system and lifestyle affect their response.
Nicola Maffulli
Department of Musculoskeletal Disorders, University of Salerno School of Medicine and Surgery, Salerno, Italy and Queen Mary University of London, Centre for Sports and Exercise Medicine, London, England.
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Surgical indications for muscle injuries
Nicola Maffulli
Department of Musculoskeletal Disorders, University of Salerno School of Medicine and Surgery, Salerno, Italy and Queen Mary University of London, Centre for Sports and Exercise Medicine, London, England.
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Surgical indications for muscle injuries
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?
Amputations Shaping Sheet
1. Sarena Gerard, Bethany Roper, and Olivia Lullie
10th Honors World Lit/Comp
Mrs. Lester
16 April 2012
Are Amputations the Defining Crisis of War Today?
Thesis:Are amputations the defining crisis of war today?Thousands of soldiers are injured during
war, and the percentage of amputees is well over 40 %. Many enlist in war knowing that there is
a risk of being severely injured, but some surface with different injuries, one of them being an
amputation. Amputations can cause grave psychological effects on the human body. Discovering
how and why an amputation occurs can aid in understanding a better road to recovery.
TS:What does an amputation occur from?
CD: War amputations are caused by stepping on hidden bombs, or being shot in a limb.
Amputations can also come from well-known war diseases, such as gangrene, or decreased blood
flow to an area of the body due to a tumor or hardening arteries, known as Peripheral Arterial
Disease (PAD).
CM1: Hidden bombs can be found anywhere on open ground in a war. Bombs are hidden
underground, under objects, and in sand.
CM2: Gangrene is an infection in an open wound where bacteria causes lack of blood flow.
Gangrene most commonly affects toes, fingers, and limbs. A soldier is most likely to contract
2. gangrene if he has an open wound, or decreased blood flow from underlying diabetes or
atherosclerosis.
CM3: Peripheral Arterial Disease (PAD) affects the limbs because blood is unable to flow to
them due to narrowed blood vessels. PAD usually affects the legs and prevents the veteran from
walking. There are no treatments for Peripheral Arterial Disease.
CS: Overall, a veteran needs to be aware of hidden bombs and the diseases that he can acquire
from war.
TS:How do field surgeons determine when an amputation is necessary, and what
measures do surgeons take before the amputation procedure?
CD1: Before an amputation, a surgeon will first check the patient for fever, cold skin near the
wound, exceedingly tender skin, wound odor, or significant infected areas of skin.
CM1:Blood tests are arranged to check the blood flow to the limbs, if any.
CM2:The human body depends on a constant supply of oxygen and nutrients from blood. If an
area of the body, such as the leg, does not receive blood and oxygen it can begin to change color
ranging from yellow to green to blue.
CM3Surgeons check for bacteria that can enter the blown open wound and cause a serious
infection.
CM4:The infection will generally emit fluid in signs of the immune system fighting off the
bacteria.
3. CM5:Signs of a serious infection can include a fever higher than 102 degrees, coughing,
headache, and nausea.
CS: Amputations should be taken seriously because they may become life threatening within just
a few hours.
TS:How does the amputation surgery happen?
CD: Choosing the correct site of incision for the amputation process can be a tricky situation for
patients who need leg amputations. If a surgeon removes less skin then he/she should, then the
wound may never heal, and has a greater risk of becoming infected.
CM1: The first process in an amputation is for an anesthesiologist to check vital signs before
putting the patient under.
CM2:The anesthesiologist may give a regional anesthetic or sedative to calm and numb the area
of incision.
CM3:Another option is to be put fully under with assistance of brain and heart monitors, blood
pressure machines, and temperature observations.
CM4:The next step is for precise incision of the amputation site. Once the patient is fully under,
or the regional sight has been numbed, the surgeon will cut off the rest of the severed limb while
leaving enough healthy skin to surround the wound in order to heal itself.
CM5: Third, the surgeon will shape the muscles of the stump as well as the nerves, so that they
will be protected in the healing process. This process also allows for correct fitting of a
prosthetic limb.
4. CM6:After bleeding decreases, it is safe for the surgeon to shape the bone in tandem with the
patient’s muscles and nerves by grinding the bone till it is smooth.
CS:Amputations are serious surgical procedures, and should be carried out by a professional
medical team with overwhelming experience in the subject for a better surgery and recovery.
TS: What types of healing processes are available after the amputation?
CD:There are two types of ways for the patient to heal after an amputation. The first is an open
flap amputation, and the second is a closed amputation.
CM1:In an open flap amputation flaps of skin are kept open around the incision siteso that the
medical care staff can clean up any dead or infected tissue around the amputation to minimize
risk of infection.
CM2:The closed amputation refers to sewing the flaps of skin together immediately after surgery
once the surgical site has been declared free of infection.
CM3:The sign of a closed amputation proves that the amputee tends to be a better healer than
most.
CS:Depending on the veteran’s situation, the surgeons will make a medical reference as to
whether or not they believe the veteran will heal better with a closed or open amputation.
5. TS: The psychological effects on an amputee are beyond what one would expect.
CD: It is common to experience negative thoughts and emotions after an amputation.
CM1:Negative thoughts are especially prevalent in people who have had an amputation due to
trauma (usually members of the armed forces who were injured while serving in Iraq or
Afghanistan).
CM2:The traumatic event that the veteran endured can eventually lead them into developing a
post-traumatic stress disorder (PTSD).
CM3: Many common emotions that amputees are exposed to are depression, anxiety, denial,
grief, and thoughts of suicide.
CM4:Additional treatment may be required, such as, antidepressants or counseling to improve an
amputee’s ability to cope with living after an amputation.
CS:In final consideration, amputees are at a huge disadvantage because they are at risk of
anything, whether it is PTSD, depression, or embarrassment. The psychological effects of an
amputation can lead to anything and everything which is why amputations are the defining crisis
in society and war today.
TS: The embarrassment felt by an amputee can cause them to exclude themselves from
society.
CD: Several amputees become very ashamed of their bodies after their amputation.
6. CM1:The appearance of the remaining limb makes the individual feel self-conscious and he will
eventually become embarrassed to be seen in public.
CM2: Amputees may convince themselves that their stump is ugly, and try to avoid looking at it
as much as possible to prevent any depressing thoughts.
CM3: Veteran’s with amputations often fear others will look at their amputated limbs before
looking at their face in conversation.
CS:All in all, amputees are apprehensive about how they will be viewed by other people.
TS: The psychological response to an amputation is determined by many variables.
CD: The three most important variables include the amputee’s personality style, the support from
their loved ones, and the economic and occupational sides of the individual.
CM1: The first factor is personality style. If the amputee is self-conscious and is very concerned
about their social standing, they are more likely to suffer psychologically from limb loss than
those who are self-confident. Individuals who are extremely invested in their physical
appearance tend to react more negatively to the loss of the limb then others.
CM2: Also, how much support the amputee has at home takes an extremely large toll on how
well the amputee adapts to his new body. Single and widowed individuals suffer more
psychological distress and difficulty in becoming accustomed to the amputation than those who
are married and already have a family. Usually, if the amputee has a supportive spouse, it is
especially helpful. A supportive partner is one who has a flexible approach, takes over functions
7. when needed, cuts back when the amputee is able to manage, and maintains the amputee's self-
esteem at all times.
CM3: Typically, if an amputee earned his living from skills that were lost with the amputation he
is more likely to experience an unpleasant response. Unlike others who have a wide range of
skills, or whose main line of work was not mainly dependent on the function of the lost limb may
experience less emotional difficulty. If the amputation causes unemployment, it creates a much
greater degree of psychological stress.
CS: In conclusion, how the amputee responds to an amputation is entirely dependent on where
their life currently stands at the time of the amputation. Whether or not they have a secure job, a
support system, and confidence within themselves are all factors that will determine the
psychological effects that the amputee will experience.
TS:What effects has this war had on the advances of prosthetic limbs?
CD:Thanks to the advances in prosthetic limbs today, veterans are able to add personal touches
such as tattoos, or chrome plated details.
CM1: Scott Summit, who is an industrial engineer, creates synthetic limbs.Synthetic limbs have
become a standard for self-expression based on customization made possible by modern
technology. Synthetics are now a bold blend of modern science and fashion statements.
CM2: In earlier prosthetics, the “Cairo toe” was discovered on a female mummy. It was a pirate
style limb made of bendable wood and leather.
8. CM3:Scott Summit uses the cutting edge suspension hard ware on titanium rods and carbon
sprinting legs. When it comes to amputees, few really want flesh toned silicone limbs with fake
veins. Scott Summit creates the most up to date and modern prosthetic limbs designed to
function with as little discomfort as possible.
CM4: Today, amputees can get different designs such as chrome plated legs, leather coated legs,
and some are laser etched with tribal tattoos.
CS:The designs of prosthetics are advancing rapidly to enhance an amputee’s comfort with the
limb.
TS:Prosthetic limbs can show personality not just practicality.
CD: Prosthetic limbs have always focused on functionality. However, today scientists have taken
the same design of a typical smart phone and taken prosthetic limbs to a whole new level. Now
prosthetic limbs are not meant just for limiting amputees’ disabilities.
CM1:Soldiers who typically have an amputation are between the ages eighteen and forty. Many
of these soldiers afterwards are considered veterans, and unable to return to war.
CM2: When unable to return to war, veterans with amputations choose to acquire prosthetic
limbs with personality, such as these designed by Scott Summit.
CM3:Scott Summit created these limbs to show that if a limb is attractively created it would not
just change the point of view of the veteran’s, but hopefully change the way society sees an
amputee.
CM4: When retired Army Sgt. Matthew Sullivan, whose right calf was blown off by a land mine
in Afghanistan went to the San Diego VA’s prosthetics lab to see his new device, his jaw
9. dropped out of amazement. Sullivan’s new limb mirrors the outlines of his good calf. On the
chrome-plated prosthetic leg is a laser-etched logo of the San Diego Padres. Whenever Sullivan
wears shorts people will greet him to marvel. “Kind of in a weird way”, Sullivan said, “you feel
like you’ve gotten a part of you back.” Scott Summit has changed a generation of prosthetic
limbs by making them out of the best titanium to not only function well, but have self-
expression.
CS:Modern technology allows veterans to not feel like they have fully lost a part of them when
they are still able to custom it as they would an actual limb.
C: Over all, an amputation can affect a person’s life from all stand points. The surgery can alter
the way that the human feels emotionally and physically, as well as the way people view them in
society. Prosthetics can help improve their self-esteem and change the outlook that other people
have on amputees. Despite how the surgery happens, and why, the veteran will have to live with
a stump for the rest of his life. Imagine the anxiety of the way people will perceive them or the
nerves before surgery. Amputations have become the defining crisis of war because they take a
toll on the way a human will function for the rest of his/her life. The amputation procedure also
plants a strain on the amputee’s family because of time consuming medical care. The surgery
must be precise and accurate according to the wound site for an adequate healing process.
Amputations change lives in many ways, therefore advantaged people should reflect on what an
amputee may feel physically and mentally before judging them.