BY-
MRS. D.N.GLORY
ALTERATIONS IN
OXYGENATION
Alteration
in
oxygenation
Hyperventilation
Hypoventilation
Hypercapnia
Hypoxia
Hypoxemic
Anemic
Stagnant
Histotoxic
Hypoxemia
Primary alteration includes the following…
Hyperventilation
• It is defined as the ventilation occurs in excess of metabolic
requirement.
• In hyperventilation the breathing pattern will be deeper and more rapid
than the normal breathing.
• The immediate results of hyperventilation is decreased in alveolar
carbon dioxide pressure (hypocapnia) and increase of pH in the blood
(respiratory alkalosis).
Hypoventilation
• Hypoventilation occurs when there is retention of co2 due to decrease in the rate and
depth of respiration and alveolar ventilation is also compromised.
• In other words hypoventilation includes hypercapnia and respiratory acidosis.
• There are certain cause and conditions which lead to hypoventilation like
COPD
Stroke affecting the respiratory center
Voluntary breath holding
Mountain sickness
Drug overdose like opioid overdose causes respiratory depression
Hypoxia
• Deficiency of oxygen to the tissues.
• Hypoxia is mainly four types
• Hypoxemic
• Anemic
• Stagnant
• Histotoxic
S/S
• Anxiety
• Restlessness
• Tachycardia/tachypnea
• Cyanosis
• Respiratory acidosis.
Hypoxemia
• Low level of oxygen in the blood / deficiency of oxygen in the arterial
blood.
• Respiratory disorders are the main reason of Hypoxemic
Causes of Hypoxemic
• Mismatch of ventilation perfusion ratio.
• Impaired alveolar diffusion.
• Decrease in the partial pressure of oxygen in inhaled air.
• Alveolar hypotension.
Anemic
• Anemia is a problem of not having enough healthy red blood cells or
hemoglobin to carry oxygen to the body's tissues.
• The capacity of blood to carry oxygen is too low.
• The hemoglobin is too small to supply the oxygen needs.
Stagnant
• The blood flow to the tissue is reduced or low, and the blood may be
normal
• There may be insufficient blood flow through the capillaries to supply
the tissues.
• It may be due to heart disease that affects the circulation or impaired
venous in return.
• It may reduce the blood supply to a particular area like Raynaud’s
disease and Buerger’s disease.
Histotoxic
• In this type of hypoxia, tissue cells are unable to make proper use of
oxygen due to poisoning of tissue cells but the amount of blood may
be normal.
• Mainly caused by the cyanide, narcotics, alcohol,
Hypercapnia
• It is also known as retention of carbon dioxide.
• There is an increase carbon dioxide level in the blood.
• Hypercapnia causes increase in the breathing and arousal during the
sleep.
S/S
• Flushed skin
• Dyspnea
• Muscle twitches
• Reduced neural activity
• Increased blood pressure.
ALTERATIONS IN OXYGENATION (OCYGEN ADMINISTRATION))

ALTERATIONS IN OXYGENATION (OCYGEN ADMINISTRATION))

  • 1.
  • 2.
  • 3.
    Hyperventilation • It isdefined as the ventilation occurs in excess of metabolic requirement. • In hyperventilation the breathing pattern will be deeper and more rapid than the normal breathing. • The immediate results of hyperventilation is decreased in alveolar carbon dioxide pressure (hypocapnia) and increase of pH in the blood (respiratory alkalosis).
  • 4.
    Hypoventilation • Hypoventilation occurswhen there is retention of co2 due to decrease in the rate and depth of respiration and alveolar ventilation is also compromised. • In other words hypoventilation includes hypercapnia and respiratory acidosis. • There are certain cause and conditions which lead to hypoventilation like COPD Stroke affecting the respiratory center Voluntary breath holding Mountain sickness Drug overdose like opioid overdose causes respiratory depression
  • 5.
    Hypoxia • Deficiency ofoxygen to the tissues. • Hypoxia is mainly four types • Hypoxemic • Anemic • Stagnant • Histotoxic
  • 6.
    S/S • Anxiety • Restlessness •Tachycardia/tachypnea • Cyanosis • Respiratory acidosis.
  • 7.
    Hypoxemia • Low levelof oxygen in the blood / deficiency of oxygen in the arterial blood. • Respiratory disorders are the main reason of Hypoxemic
  • 8.
    Causes of Hypoxemic •Mismatch of ventilation perfusion ratio. • Impaired alveolar diffusion. • Decrease in the partial pressure of oxygen in inhaled air. • Alveolar hypotension.
  • 9.
    Anemic • Anemia isa problem of not having enough healthy red blood cells or hemoglobin to carry oxygen to the body's tissues. • The capacity of blood to carry oxygen is too low. • The hemoglobin is too small to supply the oxygen needs.
  • 10.
    Stagnant • The bloodflow to the tissue is reduced or low, and the blood may be normal • There may be insufficient blood flow through the capillaries to supply the tissues. • It may be due to heart disease that affects the circulation or impaired venous in return. • It may reduce the blood supply to a particular area like Raynaud’s disease and Buerger’s disease.
  • 11.
    Histotoxic • In thistype of hypoxia, tissue cells are unable to make proper use of oxygen due to poisoning of tissue cells but the amount of blood may be normal. • Mainly caused by the cyanide, narcotics, alcohol,
  • 12.
    Hypercapnia • It isalso known as retention of carbon dioxide. • There is an increase carbon dioxide level in the blood. • Hypercapnia causes increase in the breathing and arousal during the sleep.
  • 13.
    S/S • Flushed skin •Dyspnea • Muscle twitches • Reduced neural activity • Increased blood pressure.