All of the following are true statements EXCEPT: Systemic microbial diseases always involve invasion and destruction of tissues at the site of an infection, followed by microbial spread to distant body sites Some diseases are caused by exotoxins that are produced by bacteria in localized infections and travel through the blood to cause systemic (generalized) effects The etiologic agents of human microbial diseases include members of various different groups of microbes, for example bacteria, fungi, protozoa, and viruses Infectious diseases of humans can be caused by microbes originating from outside the body; i.e., transmitted from other people, animals, or environmental sources, or from microbes living inside or upon the human body Infectious diseases represent a battle between the host's nonspecific and specific immune defenses and the microbe's ability to penetrate and avoid those defenses.

1. All of the following are true statements EXCEPT: Systemic microbial diseases always involve
invasion and destruction of tissues at the site of an infection, followed by microbial spread to
distant body sites Some diseases are caused by exotoxins that are produced by bacteria in
localized infections and travel through the blood to cause systemic (generalized) effects The
etiologic agents of human microbial diseases include members of various different groups of
microbes, for example bacteria, fungi, protozoa, and viruses Infectious diseases of humans can be
caused by microbes originating from outside the body; i.e., transmitted from other people, animals,
or environmental sources, or from microbes living inside or upon the human body Infectious
diseases represent a battle between the host's nonspecific and specific immune defenses and the
microbe's ability to penetrate and avoid those defenses