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Advancing the Prevention and Cure of Cancer through Research, Strategic Leadership, and Partnerships Report to the National Cancer Advisory Board   Geoffrey M. Wahl, Ph.D.  President, AACR Bethesda, MD February 6, 2007
AACR and NCI - Shared Missions AACR To prevent and cure cancer through  research, education, communications, and collaborations NCI   Reduce the burden and eliminate adverse outcomes  of cancer by leading an integrated effort to advance fundamental knowledge about cancer across a dynamic continuum of discovery, development, and delivery
AACR and NCI Collaborations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
“ Cancer Research is Working” ,[object Object],[object Object],[object Object],American Cancer Society. Cancer Facts & Figures, 2007.
“ Cancer Research is Working” The Economic Impact ,[object Object],[object Object],[object Object],*Cancer Center Directors’ Report to NCI, 2006; American Cancer Society. Cancer Facts & Figures, 2007
“ Cancer Research is Working” …and shows a positive economic return on investment ,[object Object],[object Object],[object Object],[object Object],[object Object],Murphy, K.M. and Topel, R.H., Journal of Political Economy, 2006; 114(5), 871-904
The Cancer “Tsunami” ,[object Object],[object Object],[object Object],[object Object],A Tsunami may come with little warning, leaving no time for preparation. By contrast, we have warning of this  LOOMING CANCER CRISIS , and our investment in research has prepared us to act  NOW ! Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg LX, Edwards . SEER Cancer Statistics Review, 1973–1998. National Institute of Health. 2000 NIH publication 00-2789   Yancik, R, Holmes, ME. NIA/NCI Report of the Cancer Center Workshop (June 13–15, 2001). Exploring the Role of Cancer Centers for Integrating Aging and Cancer Research. 2002.
AACR Core Characteristics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sub-fields of Cancer Research Encompassed by AACR Membership ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Our diverse scientific scope creates a unique environment  for cross-disciplinary interactions and research integration
AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms:  - Scientific Think Tanks   - Annual Meetings - Task Forces - Special Conferences - Scientific Committees   - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally  and internationally
AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms:  - Scientific Think Tanks   - Annual Meetings - Task Forces - Special Conferences - Scientific Committees   - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally  and internationally
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Council of Scientific Advisors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms:  - Scientific Think Tanks   - Annual Meetings - Task Forces - Special Conferences - Scientific Committees   - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally  and internationally
AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms:  - Scientific Think Tanks   - Annual Meetings - Task Forces - Special Conferences - Scientific Committees   - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally  and internationally
Advances Contributing to Reduced Cancer Mortality ,[object Object],[object Object],[object Object],Significant progress has been made because of  advances in basic, translational, and clinical research, but challenges remain....
Advances Contributing to Reduced Cancer Mortality ,[object Object],[object Object],[object Object],Significant progress has been made because of  advances in basic, translational, and clinical research, but challenges remain....
Cancer Prevention Prevention can intervene at all stages of carcinogenesis: Areas encompassed by Prevention: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
AACR - Advancing Prevention Research ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Public Education - A Key Element  for Prevention In Britain:   27% of all questioned, (34% of smokers, 36% of overweight, and 43% of poor, but only 14% of wealthy) feel they can do nothing to alter cancer risk. (Cancer Research UK study, 2007) In America:  36% feel that fate determines whether they will get cancer. (ACS Poll, Reported on CNN)
AACR - Making Information About Cancer More Accessible ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Advances Contributing to Reduced Cancer Mortality ,[object Object],[object Object],[object Object],Significant progress has been made because of  advances in basic, translational, and clinical research, but challenges remain....
Advances Contributing to Reduced Cancer Mortality ,[object Object],[object Object],[object Object],Significant progress has been made because of  advances in basic, translational, and clinical research, but challenges remain....
Early Detection and Molecular Diagnostics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Advances Contributing to Reduced Cancer Mortality ,[object Object],[object Object],[object Object],Significant progress has been made because of  advances in basic, translational, and clinical research, but challenges remain....
Advances Contributing to Reduced Cancer Mortality ,[object Object],[object Object],[object Object],Significant progress has been made because of  advances in basic, translational, and clinical research, but challenges remain....
AACR - Accelerating Progress in Translational Research and Cancer Medicine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
AACR’s Vision for the Future of  Cancer Therapeutics ,[object Object],[object Object],[object Object],[object Object],[object Object]
AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms:  - Scientific Think Tanks   - Annual Meetings - Task Forces - Special Conferences - Scientific Committees   - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally  and internationally
AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms:  - Scientific Think Tanks   - Annual Meetings - Task Forces - Special Conferences - Scientific Committees   - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally  and internationally
Global Cancer Burden B. W. Stewart and P. Kleihues,  World Cancer Report , WHO-IARC. Lyon: IARC Press, 2003 New Cancer Cases 2000 - 10,000,000 2010 - 15,000,000 New Cancer Deaths 2000 - 6,200,000 2010 - 10,000,000
International Scientific  Partnerships Italian Cancer Society, BACR, EACR, Fredrich Miescher Institute, FECS, EORTC,  ESMO, IARC, ICA, ISREC, UICC Australian Cancer Society, MOGA National Health Research Institute of Taiwan, JCA, JSMO, CACA, KCA Brazilian Association of Philanthropic Institutions to Combat Cancer NCI of Canada NCI, NCCR, OVAC, Friends of Cancer Research, CRPF, NFCR, ASH, ASCO, EMS, ONS, Other Organizations, and Industry AORTIC
Persistent Problem in Cancer  Health Disparities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],While access to cancer care is a big issue,  other factors play a strong role:
AACR - Committed to Eliminating  Cancer Health Disparities ,[object Object],[object Object],[object Object],[object Object],[object Object]
AACR Annual Meeting 2007 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ronald A. DePinho, M.D. Program Committee Chairperson Professor of Medicine  Harvard Medical School Dana-Farber Cancer Institute Boston, MA
AACR Centennial 2007 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A Century of Progress in Cancer Research -  A Future of Prevention and Cures Ideal opportunity to draw public attention to  the importance of cancer research
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],From the Trenches
The Cancer Research “Engine”
The Cancer Research “Engine”
The Cancer Research “Engine”
AACR Centennial Grant Research Fund ,[object Object],[object Object],[object Object],[object Object],[object Object]
By Lance Armstrong Special to CNN AUSTIN, Texas (CNN) -- I'm not known for my patience. Patience is a polite quality and often appropriate, but it rarely gets things done. Impatience, however, is the hunger for results  and intolerance for excuses and delays. Impatience got me over countless mountain passes, across the finish line in New York  City and through four rounds of ruthless chemotherapy 10 years ago. Last week’s announcement by the American Cancer Association that the number of cancer deaths fell in the United States for the second year in a row was celebrated… Fighting the terrorist within  B y Geoffrey M. Wahl  N ovember 17, 2006   Fighting cancer bears a striking resemblance to our fight against terrorism. Cancer strikes just as randomly and unpredictably, and its causes suffering, death and great personal loss to family, friends and loved ones left behind. The Tennessean (Nashville, Tennessee) August 28, 2006 Monday  1ST Edition We're beating cancer, so why stall funding for research? Earlier this year, with surprisingly little media attention, we celebrated a major milestone in the fight against cancer -- for the first time in record-keeping history, the number of American lives lost to cancer declined.
AACR Science Policy and Legislative Activities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ensure that cancer research becomes a  national priority AGAIN!
AACR - Strengthening Collaborations with Other Sectors and Groups ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
AACR and NCI - Shared Missions Optimize research opportunities today to ensure a competitive and productive cancer research enterprise  for tomorrow!! ,[object Object],[object Object],[object Object]

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Advancing The Prevention And Cure Of Cancer

  • 1. Advancing the Prevention and Cure of Cancer through Research, Strategic Leadership, and Partnerships Report to the National Cancer Advisory Board Geoffrey M. Wahl, Ph.D. President, AACR Bethesda, MD February 6, 2007
  • 2. AACR and NCI - Shared Missions AACR To prevent and cure cancer through research, education, communications, and collaborations NCI Reduce the burden and eliminate adverse outcomes of cancer by leading an integrated effort to advance fundamental knowledge about cancer across a dynamic continuum of discovery, development, and delivery
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10. AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms: - Scientific Think Tanks - Annual Meetings - Task Forces - Special Conferences - Scientific Committees - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally and internationally
  • 11. AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms: - Scientific Think Tanks - Annual Meetings - Task Forces - Special Conferences - Scientific Committees - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally and internationally
  • 12.
  • 13. AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms: - Scientific Think Tanks - Annual Meetings - Task Forces - Special Conferences - Scientific Committees - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally and internationally
  • 14. AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms: - Scientific Think Tanks - Annual Meetings - Task Forces - Special Conferences - Scientific Committees - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally and internationally
  • 15.
  • 16.
  • 17.
  • 18.
  • 19. Public Education - A Key Element for Prevention In Britain: 27% of all questioned, (34% of smokers, 36% of overweight, and 43% of poor, but only 14% of wealthy) feel they can do nothing to alter cancer risk. (Cancer Research UK study, 2007) In America: 36% feel that fate determines whether they will get cancer. (ACS Poll, Reported on CNN)
  • 20.
  • 21.
  • 22.
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  • 24.
  • 25.
  • 26.
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  • 28. AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms: - Scientific Think Tanks - Annual Meetings - Task Forces - Special Conferences - Scientific Committees - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally and internationally
  • 29. AACR - Driving the Scientific Agenda  Identify and promote new and promising research opportunities, interventions, and strategies to hasten progress  Foster creativity and innovation in cancer research through various mechanisms: - Scientific Think Tanks - Annual Meetings - Task Forces - Special Conferences - Scientific Committees - Educational Workshops - Scientific Working Groups - Publications & Website  Engage in synergistic partnerships, both nationally and internationally
  • 30. Global Cancer Burden B. W. Stewart and P. Kleihues, World Cancer Report , WHO-IARC. Lyon: IARC Press, 2003 New Cancer Cases 2000 - 10,000,000 2010 - 15,000,000 New Cancer Deaths 2000 - 6,200,000 2010 - 10,000,000
  • 31. International Scientific Partnerships Italian Cancer Society, BACR, EACR, Fredrich Miescher Institute, FECS, EORTC, ESMO, IARC, ICA, ISREC, UICC Australian Cancer Society, MOGA National Health Research Institute of Taiwan, JCA, JSMO, CACA, KCA Brazilian Association of Philanthropic Institutions to Combat Cancer NCI of Canada NCI, NCCR, OVAC, Friends of Cancer Research, CRPF, NFCR, ASH, ASCO, EMS, ONS, Other Organizations, and Industry AORTIC
  • 32.
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  • 37. The Cancer Research “Engine”
  • 38. The Cancer Research “Engine”
  • 39. The Cancer Research “Engine”
  • 40.
  • 41. By Lance Armstrong Special to CNN AUSTIN, Texas (CNN) -- I'm not known for my patience. Patience is a polite quality and often appropriate, but it rarely gets things done. Impatience, however, is the hunger for results and intolerance for excuses and delays. Impatience got me over countless mountain passes, across the finish line in New York City and through four rounds of ruthless chemotherapy 10 years ago. Last week’s announcement by the American Cancer Association that the number of cancer deaths fell in the United States for the second year in a row was celebrated… Fighting the terrorist within B y Geoffrey M. Wahl N ovember 17, 2006 Fighting cancer bears a striking resemblance to our fight against terrorism. Cancer strikes just as randomly and unpredictably, and its causes suffering, death and great personal loss to family, friends and loved ones left behind. The Tennessean (Nashville, Tennessee) August 28, 2006 Monday 1ST Edition We're beating cancer, so why stall funding for research? Earlier this year, with surprisingly little media attention, we celebrated a major milestone in the fight against cancer -- for the first time in record-keeping history, the number of American lives lost to cancer declined.
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