This document discusses advances in personalized cancer treatment and improving patient quality of life. It outlines goals of anti-cancer therapy including maximizing survival, treating symptoms, and improving quality of life. Studies show quality of life scores can predict survival, and improvements in physical functioning correlate with better outcomes. Targeted and precision therapies are highlighted like treatments for EGFR mutations in lung cancer and BRAF mutations in melanoma. Challenges in developing precision medicines are addressed, but new technologies are making genome sequencing cheaper and more accessible to guide individual treatment.