ACUTE GASTROENTERITIS
A.JAHNAVI
B20112
PHARMD3RD YR
CCPER
INTRODUCTION
Acute gastro enteritis is an infection or inflammation of
digestive tract,particularly the stomach and intestine
It is frequently referred to as the stomach flu or intestinal
flu.
Gastroenteritis is also known as infectious diarrhoea
Symptoms may include diarrhoea,vomiting,abdominal
pain,fever,dehydration.
ETIOLOGY
Gastroenteritis is usually caused by virus,however gut
bacteria,parasites,fungi can also cause gastro enteritis.
In children ,Rota virus is the most common cause of severe
disease.
Eating improperly prepared food,drinking contaminated
water or close contact with infected person can spread the
disease.
PATHOPHYSIOLOGY
Vomiting or diarrhoea occurs due to inflammation of small or large
bowel,often due to infection.
The changes in the small bowel are typically non inflammatory,while
the ones in large bowel are inflammatory.
A no. of parasites can cause gastroenteritis.
SYMPTOMS
Bloating
Loss of appetite
Nausea and vomiting
Diarrhoea
Abdominal pain
Bloody stools
Lethargy
DIAGNOSIS
Diagnostic methods may include:
medical history
physical examination
blood tests
stool tests
TREATMENT AND MANAGEMENT
Treatment depends on cause but, may include:
Plenty of fluids and right diet
Oral rehydration drinks.
Admission to hospital and intravenous fluid replacement in
severe cases.
Antibiotics,if bacteria are cause.
PREVENTION
Wash your hands thoroughly with soap and water before
eating food.
Make sure foods are thoroughly cooked.
Avoid uncooked foods
Drink boiled water.
CASE PRESENTATION
ON
ACUTE GASTRO ENTERITIS
SUBJECTIVE
CHIEF COMPLAINTS:
A 37 year old male patient was admitted to hospital with
chief complaints of vomitings,diarrhoea,abdominal pain.
PAST MEDICAL HISTORY:
HTN since 2 yrs.
OBJECTIVE
SYSTEMIC EXAMINATION:
CVS :S1S2+
GRBS :107Mg/dl
 PHYSICAL EXAMINATION:
Temperature:NORMAL
HR : 88/MIN
RR :22/MIN
BP :120/70MMHG
Spo2: 97%
LAB INVESTIGATIONS
Parameters Patient range Normal value Units
Hb 15.3 14 -18 gram/dl
WBC 5000 4500 - 11000 cell/l
S.cr 1.0 0.74-1.35 mg/dl
Na 136 135-145 mmol/l
K 3.3 3.6-5.2 mmol/l
urea 15 5-20 mg/dl
ASSESSMENT
• DAY-1
Pt : C/C
Temp : afebrile
BP : 130/80 mmhg
SPO2 : 98%
P/A : soft
• MEDICATIONS
Inj.pantop 40mg IV BID
Inj.zofer 40mg IV BID
Inj.ornidazole 100ml IV BID
Inj.oflox 100ml IV BID
Cap.radotil 100mg P/O TID
Cap.rifagut 400ml P/O BID
• DAY-2
Pt :C/C
Temp : afebrile
BP : 130/90 mmhg
PR : 80/min
SPO2 : 98%
P/A :soft
• MEDICATIONS
Inj.pantop 40mg IV BID
Inj.zofer 40mg IV BID
Inj.ornidazole 100ml IV BID
Inj. Oflox 100ml IV TID
Cap. Radotil 100mg P/O TID
• DAY- 3
Pt : C/C
Temp : afebrile
BP : 120/70mmhg
PR : 80/min
SPO2 : 98%
P/A :soft
• MEDICATIONS
Inj.ornidazole 100ml IV BID
Inj.oflox 200ml IV BID
Inj.PAN 40mg IV BID
Tab.rifagut 40mg P/O BID
IVF.Katrilyte 100ml/hr
• DAY-4
Pt : C/ C
Temp : afebrile
BP : 100/70mmhg
PR : 78/min
SPO2 : 97%
CVS : S1S2+
P/A : Soft
• MEDICATIONS
CST
• DAY-5
Pt : C/C
Temp : afebrile
BP :100/70mmhg
PR : 78/min
SPO2 : 97%
CVS :S1S2+
P/A : Soft
• MEDICATIONS
CST
monitor vitals
plan for discharge
DRUG CHART
Brand name Generic name category MOA Dose Frequency Route Use
Inj.pantop pantoprazole PPI Blocks
h+k+/ATP
pump
40mg BID IV Prevents
acid
secretion
Inj.zofer Ondansetron antiemetic Inhibit
5HT3
Receptor
40mg BID IV Prevent
nausea and
vomiting
Inj.ornidazole ornidazole Anti-
amoebic
Inhibit
bacterial
protein
synthesis
100ml TID IV Treat
intestinal
infections
Inj.oflox ofloxacin fluoroquin
olones
Inhibit
bacterial
DNA
gyrase
100ml BID IV Treat
bacterial
infections
Cap.redotil Racecadotril Anti-
diarrhoeal
Reduce
secretion
from
intestine
100mg TID ORAL Treat
diarrhoea
DISCHARGE MEDICATIONS:
1) Tab.zenflox-OZ BID - 3days
2) Tab.Pan 40mg OD - 10days
3) Tab.VSL-3 BID - 5days
4) Tab.mvt OD - 10 days
REFERENCE
• The handbook of pharmacotherapeutics by dipiro.
• Webmd.com.
THANK YOU

Acute gastroenteritis case presentation

  • 1.
  • 2.
    INTRODUCTION Acute gastro enteritisis an infection or inflammation of digestive tract,particularly the stomach and intestine It is frequently referred to as the stomach flu or intestinal flu. Gastroenteritis is also known as infectious diarrhoea Symptoms may include diarrhoea,vomiting,abdominal pain,fever,dehydration.
  • 3.
    ETIOLOGY Gastroenteritis is usuallycaused by virus,however gut bacteria,parasites,fungi can also cause gastro enteritis. In children ,Rota virus is the most common cause of severe disease. Eating improperly prepared food,drinking contaminated water or close contact with infected person can spread the disease.
  • 4.
    PATHOPHYSIOLOGY Vomiting or diarrhoeaoccurs due to inflammation of small or large bowel,often due to infection. The changes in the small bowel are typically non inflammatory,while the ones in large bowel are inflammatory. A no. of parasites can cause gastroenteritis.
  • 5.
    SYMPTOMS Bloating Loss of appetite Nauseaand vomiting Diarrhoea Abdominal pain Bloody stools Lethargy
  • 6.
    DIAGNOSIS Diagnostic methods mayinclude: medical history physical examination blood tests stool tests
  • 7.
    TREATMENT AND MANAGEMENT Treatmentdepends on cause but, may include: Plenty of fluids and right diet Oral rehydration drinks. Admission to hospital and intravenous fluid replacement in severe cases. Antibiotics,if bacteria are cause.
  • 8.
    PREVENTION Wash your handsthoroughly with soap and water before eating food. Make sure foods are thoroughly cooked. Avoid uncooked foods Drink boiled water.
  • 9.
  • 10.
    SUBJECTIVE CHIEF COMPLAINTS: A 37year old male patient was admitted to hospital with chief complaints of vomitings,diarrhoea,abdominal pain. PAST MEDICAL HISTORY: HTN since 2 yrs.
  • 11.
    OBJECTIVE SYSTEMIC EXAMINATION: CVS :S1S2+ GRBS:107Mg/dl  PHYSICAL EXAMINATION: Temperature:NORMAL HR : 88/MIN RR :22/MIN BP :120/70MMHG Spo2: 97%
  • 12.
    LAB INVESTIGATIONS Parameters Patientrange Normal value Units Hb 15.3 14 -18 gram/dl WBC 5000 4500 - 11000 cell/l S.cr 1.0 0.74-1.35 mg/dl Na 136 135-145 mmol/l K 3.3 3.6-5.2 mmol/l urea 15 5-20 mg/dl
  • 13.
    ASSESSMENT • DAY-1 Pt :C/C Temp : afebrile BP : 130/80 mmhg SPO2 : 98% P/A : soft • MEDICATIONS Inj.pantop 40mg IV BID Inj.zofer 40mg IV BID Inj.ornidazole 100ml IV BID Inj.oflox 100ml IV BID Cap.radotil 100mg P/O TID Cap.rifagut 400ml P/O BID
  • 14.
    • DAY-2 Pt :C/C Temp: afebrile BP : 130/90 mmhg PR : 80/min SPO2 : 98% P/A :soft • MEDICATIONS Inj.pantop 40mg IV BID Inj.zofer 40mg IV BID Inj.ornidazole 100ml IV BID Inj. Oflox 100ml IV TID Cap. Radotil 100mg P/O TID
  • 15.
    • DAY- 3 Pt: C/C Temp : afebrile BP : 120/70mmhg PR : 80/min SPO2 : 98% P/A :soft • MEDICATIONS Inj.ornidazole 100ml IV BID Inj.oflox 200ml IV BID Inj.PAN 40mg IV BID Tab.rifagut 40mg P/O BID IVF.Katrilyte 100ml/hr
  • 16.
    • DAY-4 Pt :C/ C Temp : afebrile BP : 100/70mmhg PR : 78/min SPO2 : 97% CVS : S1S2+ P/A : Soft • MEDICATIONS CST
  • 17.
    • DAY-5 Pt :C/C Temp : afebrile BP :100/70mmhg PR : 78/min SPO2 : 97% CVS :S1S2+ P/A : Soft • MEDICATIONS CST monitor vitals plan for discharge
  • 18.
    DRUG CHART Brand nameGeneric name category MOA Dose Frequency Route Use Inj.pantop pantoprazole PPI Blocks h+k+/ATP pump 40mg BID IV Prevents acid secretion Inj.zofer Ondansetron antiemetic Inhibit 5HT3 Receptor 40mg BID IV Prevent nausea and vomiting Inj.ornidazole ornidazole Anti- amoebic Inhibit bacterial protein synthesis 100ml TID IV Treat intestinal infections Inj.oflox ofloxacin fluoroquin olones Inhibit bacterial DNA gyrase 100ml BID IV Treat bacterial infections Cap.redotil Racecadotril Anti- diarrhoeal Reduce secretion from intestine 100mg TID ORAL Treat diarrhoea
  • 19.
    DISCHARGE MEDICATIONS: 1) Tab.zenflox-OZBID - 3days 2) Tab.Pan 40mg OD - 10days 3) Tab.VSL-3 BID - 5days 4) Tab.mvt OD - 10 days
  • 20.
    REFERENCE • The handbookof pharmacotherapeutics by dipiro. • Webmd.com.
  • 21.