Brief introduction about uveitis for 4th-year eye students. it is mainly targeted towards the clinical side. and includes basic symptoms signs and treatment options. images are all included for better understanding. It is an acute version for chronic uveitis stay tuned for more presentations. hope this helps with your clinical roatations

1. ACUTE ANTERIOR
UVEITIS
MUNEEB ALI TASLEEM

2. Case presentation
 A 30 year old male presented in eye opd with the
complaints of pain in right eye which was sudden
in onset. Patient said that he is having decreased
vision and photophobia with increased
lacrimation and redness in that eye. On
examination visual acuity was reduced and
keratic preciptates was visible. Iris was muddy
and the pupil was miotic with the reduced red
reflex

3. Uveal tract
Vascular layer
Three parts
1.Choroid
2.Ciliary body
3.Iris

5. Choroid
 Extends from ora serrata to optic dics.
 Three layer
1. Suprachroidal lamina
2. Stroma or vascular layer
3. Bruch’s membrane
Function: provides nutrition to retina and up
to outer plexiform layer

7. Layers of choroid:

8. Ciliary body:
Extends from ora serrata to scleral
spur
Forward continuation of choroid

11. Layers of ciliary body
1.Pars plicata(ciliary
muscle,stroma,ciliary
process)
2.Pars plana(relatively
avascular)

12. Function of ciliary body
Aqueous humor formation by
ciliary process
Accommodation by ciliary muscle

13. Iris
 Attached to anterior surface of ciliary body
 Divides the eye into anterior and posterior
chamber

14. Anterior limiting membrane
Posterior limiting
membtrane

15. Function
Regulates amount of light entering
Pupil size( 2-4mm)

16. Uveitis;
Inflammation of uveal tract
Iris,ciliary body and choroid

17. Classification
Anatomical classification
1.Anterior uveitis(iris, pars plicata)
2.Intermediate uveitis(pars
plana,vitreous humor)
3.Posterior uveitis(choroid,retina)
4.Pan uveitis(all parts)

18. Clinical classification;
Acute uveitis(6 week- 3month)
Chronic uveitis(longer than 3
month)
Recurrent uveitis( repeated
episode,inactivity for three month)

19. Histological classification
Non granulomatous uveitis(medium
size keratic precipitates)
Granulomatous uveitis(mutton fat
Keratic preciptates and iris nodules)

20. Aetiology:
 Infective(exogenous, endogenous)
 Non-infective(toxin and chemical
mediators)
 Autoimmune disease(ankylosing spondylitis,
psoriatic arthritis)
 idiopathic

21. Acute anterior uveitis:
Acute iridocyclitis
Acute inflammation of iris and ciliary
body
Aetiology(idiopathic)

22. Pathogenesis
 Acute inflammation of iris and ciliary body
 Spasm of ciliary body( difficulty in
accommodation)
 Vascular dilation
 Increased capillary permeability
 Chemotaxis of inflammatory cell in the eye
 Secondary glaucoma( due to blockage of angle)

23. Symptoms
 Sudden onset of pain
 Decreased vision
 Photophobia
 Lacrimation
 Redness of eye

24. Signs
 Visual acuity reduced
 Limbus :circumcorneal congestion
 Cornea:keratic preciptates(inflammatory cells deposited on the
endothelium of cornea)
 Hypopyon:white blood cells in the anterior chamber/ pus
 Iris muddy(exudate)
 Pupil: miosis ( spasm of pupillary sphincter)
 Posterior synechiae: adhesion between pupil margin and
the anterior lens due to exudate
 Red reflex poor
 Tenderness of eyeball on palpations

33. Treatment
Relieve symptoms
Treat underlying cause
Prevent complications

34. Prevent posterior synechiae,
avoid secondary glaucoma
Decrease capillary
permeability