According to the World Obesity Federation, the total number of adults living with obesity is expected to increase by more than 115% from 2010 to 2030, rising from 524 million to 1.13 billion.
According to the World Obesity Federation, the total number of adults living with obesity is expected to increase by more than 115% from 2010 to 2030, rising from 524 million to 1.13 billion.
Similar to According to the World Obesity Federation, the total number of adults living with obesity is expected to increase by more than 115% from 2010 to 2030, rising from 524 million to 1.13 billion.
According to the World Obesity Federation, the total number of adults living with obesity is expected to increase by more than 115% from 2010 to 2030, rising from 524 million to 1.13 billion.
1.
CHS 412 Lecture2
Health Education to prevent and control Obesity
and its danger
Dr. Ebtisam Fetohy
2.
Objectives of thelecture
At the lecture the students will be able to:
1-Define Obesity
2-List different methods for measurements of obesity
and overweight
3-Classify obesity
4-Identify advantages and disadvantages of BMI to
assess health risks
5-List Causes of obesity
6-List diseases associated with obesity
3.
Obesity as apublic health problem
Obesity as a public health problem
The rapid rise in the prevalence of obesity in
both rich and poor countries in recent years
has been described as an epidemic.
• At the global level, excess body weight is the
sixth most important risk factor for ill health.
• Many adverse health outcomes are strongly
associated with obesity.
4.
How is obesitymeasured?
How is obesity measured?
It is defined as the excessive accumulation of body fat.
-There are a number of ways to measure body fat:
There are a number of ways to measure body fat:
Measurements that are simple, cheap and
Measurements that are simple, cheap and
appropriate for routine use include:
appropriate for routine use include:
• Waist circumference
• Hip circumference
• Waist-to-hip circumference ratio
• Indices derived from weight and height, e.g. body
mass index
• skin fold thickness using calipers (e.g. triceps,
scapular)
5.
How is obesitymeasured?
How is obesity measured?
• Measurements of body fat that are
Measurements of body fat that are
expensive and require special equipment
expensive and require special equipment
and highly trained personnel include:
and highly trained personnel include:
Underwater weighing
Bioelectrical impedanceالمعاوقة
Computerized topography
6.
Classification of obesity(1) –
Classification of obesity (1) –
‘apples’ and ‘pears
‘apples’ and ‘pears’
’:
:
1.
1. The apple shape: also called “android
The apple shape: also called “android”,
“abdominal” or “central”
“central” obesity
• People with high waist-to-hip ratios are "apples",
• Their body fat is distributed mainly on the upper
trunk, the chest and abdomen giving the typical
‘apple shape’
• Individuals are mostly male
• A waist-to-hip ratio >1.0 for men and >0.8 for
women indicates an increased risk of cardio-
cardio-
vascular
vascular disease and diabetes mellitus
diabetes mellitus
7.
Classification of obesity(1) –
Classification of obesity (1) –
‘apples’ and ‘pears’
‘apples’ and ‘pears’:
:
2.
2. The pear shape
The pear shape: also called
also called “gynaeoid
“gynaeoid” or “
“peripheral
peripheral”
obesity
obesity
• People with lower waist to hip ratios are "pears“ –
• Their body fat is distributed mainly on the lower trunk,
the hips and thighs giving the typical ‘pear shape’.
• Individuals are mostly female.
• Associated health risks are minimal if any. Obesity can be
classified into two groups on the basis of body fat
distribution and the waist-to-hip circumference ratio.
-This simple classification is easily understood by the public
and also predicts the risk of obesity-related health
problems.
8.
Classification of obesity(2) –
Classification of obesity (2) –
body mass index (BMI)
body mass index (BMI):
:
• Classification of obesity (2) – body mass index
(BMI) BMI =
= weight in kilograms - kg/m2-
square of height in meters
9.
Over weight definition1
Over weight definition 1
Note: Although overweight is identified by a BMI
Although overweight is identified by a BMI
of ≥ 25.0 kg/m2
of ≥ 25.0 kg/m2, the risks of obesity-associated
diseases, such as:
• Diabetes,
• Hypertension and
• Dyslipidaemia, increase from a BMI of about
increase from a BMI of about
21.0 kg/m2.
21.0 kg/m2.
NIH: A weight and height chart is a useful
clinical tool to determine a person’s BMI
10.
Advantages of usingBMI to classify obesity
Advantages of using BMI to classify obesity
• It is low-cos
low-cost and
• Easy
Easy to use for health professionals for assessing
individuals, it is commonly used to determine desirable
body weights and
• It allows people to compare their own weight status
compare their own weight status to that
of the general population
• It correlates well with the amount of body fat
correlates well with the amount of body fat as measured
by more complex techniques
• It predicts dangers associated with obesity
predicts dangers associated with obesity; as BMI
increases the risk for diseases increases
• It is a useful screening tool
useful screening tool to use at the population level
and,
• Because it is universally accepted, BMI reference data is
available for many different populations
11.
Disadvantages of BMI
Disadvantagesof BMI
BMI: Which of these men is at risk of ill health and why? (a)
(b) These men have the same height, weight and BMI, but
have different percent body fat BMI calculated as follows:
BMI = 28.4 kg/ m2. Although BMI is equally high in both
men, it is not known:
it is not known:
(a) It is due to lean body mass or
(b) It is due to body fat.
-This shows that, used alone, a high BMI is not diagnostic of
obesity. BMI also varies with age and sex in those <18
years. These are some of the disadvantages of using BMI
to assess health risks.
12.
Questions
Questions
Put “true” or“false”:
• Obesity is the excessive accumulation of body fat
• Body mass index (BMI) is the most universally
accepted index of obesity
• A woman with a BMI of 46.0 is overweight
• To calculate the BMI of an individual, we need
the weight, height and body fat distribution
• A man with weight 76 kg and height 1.55 m is
obese.
13.
Question 2:
Question 2:
A25 year old male athlete weighs 87.3kg and
has a height of 1.75m:
A. Calculate his BMI How would you classify his
BMI ?
B. Is the classification of obesity based on BMI
reliable for this man and, if not, why?
14.
The global burdenof obesity
The global burden of obesity
• The USA has the highest obesity rate in the world.
• IN American adults, 50m are obese (BMI >30.0) and
• 6m have class III obesity (BMI >40.0).
• Obesity in adolescents has increased from 5% in 1966 -
1970 to 14% in 1999.
15.
Obesity in adultson the increase - worldwide
Obesity in adults on the increase - worldwide
• Dramatic increases in obesity in recent years is
not confined to the USA.
• Obesity in children living in poorer
countries: Obesity in children living in poorer
countries Africa & Middle East: 4 year olds
• Latin America and Caribbean: 4-10 year olds
• Prevalence of overweight in 10-year old
children in selected countries
16.
The burden ofobesity – costly, deadly…
The burden of obesity – costly, deadly…:
:
• The financial burden of obesity: WHO data show
that obesity accounts for 5-10% of the total health
care budget in several developed countries
• This is probably a low estimate as not all of the cost
of management of obesity and its related problems
can be calculated
• In 2000, the U.S. spent $117 billion on obesity (9%
of the national total health budget)
17.
The burden ofobesity – costly, deadly…
The burden of obesity – costly, deadly…:
:
• The morbidity and mortality burden of obesity:
The morbidity and mortality burden of obesity: Overall,
about 2.5 millions deaths are attributed to
overweight/obesity worldwide In the UK, about 30,000
deaths are attributable to obesity.
• Ten times this figure occurs in the US
Ten times this figure occurs in the US where obesity is
the second
second greatest preventable cause of death following
smoking
smoking
• Nearly 70% of cases of cardiovascular disease
70% of cases of cardiovascular disease are
associated with obesity
• Obesity predisposes to an overall reduction of quality of
overall reduction of quality of
life and
life and premature death from diet related, chronic non-
premature death from diet related, chronic non-
communicable diseases
communicable diseases
18.
People who areobese or overweight also have a
People who are obese or overweight also have a
lower life expectancy
lower life expectancy
• A 40-year-old nonsmoking male who is overweight will
A 40-year-old nonsmoking male who is overweight will
lose 3.1 years of life expectancy; one who is obese will lose
lose 3.1 years of life expectancy; one who is obese will lose
5.8 years.
5.8 years.
• A 40-year-old overweight nonsmoking female will lose 3.3
A 40-year-old overweight nonsmoking female will lose 3.3
years of life expectancy; one who is obese will lose 7.1
years of life expectancy; one who is obese will lose 7.1
years.
years.
19.
Questions 3:
Questions 3:
Write“T” or “F”
Write “T” or “F”:
:
1.
1. Obesity is a worldwide public health problem
Obesity is a worldwide public health problem
2.
2. Obesity is not a major public health problem in
Obesity is not a major public health problem in
developing nations
developing nations
3.
3. The highest rate of obesity is found in the U.S.A
The highest rate of obesity is found in the U.S.A
4.
4. Obesity related problems account for less than 5%
Obesity related problems account for less than 5%
of healthcare budget in developed countries
of healthcare budget in developed countries
5.
5. Obesity leads to premature death from diet related
Obesity leads to premature death from diet related
chronic communicable diseases.
chronic communicable diseases.
20.
Calories in andcalories out – the imbalance
Calories in and calories out – the imbalance
• The energy value of food can be expressed in calories.
Obesity occurs when a person consumes more calories
Obesity occurs when a person consumes more calories
than his/her body needs.
than his/her body needs.
• Excess calories are stored as fat and lead to weight
increase. For e.g., consuming 3,500 calories
3,500 calories more than
the body needs results in a gain of 0.45kg of fat
0.45kg of fat.
• The factors
factors which affect the balance between calories in
balance between calories in
and calories out differ from one person to another
and calories out differ from one person to another.
• Obesity is believed to result from a complex interplay of
Obesity is believed to result from a complex interplay of
the following factors:
the following factors:
1. Genetic factors
2. Socio-economic (lifestyle and diet)
3. Cultural factors
4. Psychological and medical factors
21.
Genetic factors
Genetic factors:
:
•We know that obesity tends to run in families,
suggesting a genetic cause.
• Although, families also share diet
diet and lifestyle
lifestyle, both of
which contribute to obesity, research has shown that
genetic factors account for as much 80%
80% of the link
between heredity and obesity.
• Studies in adoptees
Studies in adoptees المتبنون
المتبنونand twins strongly support
and twins strongly support
this link:
this link: Adults who were adopted as children have
weights closer to their biological parents than to their
adoptive parents
• Monozygotic (identical) twins
Monozygotic (identical) twins show a much stronger
correlation in body weight than dizygotic (non-
than dizygotic (non-
identical) twins.
identical) twins.
22.
Socio-economic factors andlifestyle
Socio-economic factors and lifestyle
Diet Apart from our genes, environmental factors
also contribute to the recent surge مفاجئة زيادة in
obesity. The following changes in diets across the
The following changes in diets across the
world play a major role:
world play a major role:
• Increase in consumption of energy dense foods –
containing animal fats
• Decrease consumption of complex carbohydrates
and fibre - coarse grains, fruits
• Increase intake of salt
salt and alcohol
23.
Socio-economic factors andlifestyle
Socio-economic factors and lifestyle
In recent years, societies of the western world have enjoyed
In recent years, societies of the western world have enjoyed
an over abundance of food –
an over abundance of food –
• So people feast تمتعon larger portions at low prices.
• As this “affluence” اليسرcreeps into the urban centres of
the developing world, we are beginning to see a rise in
obesity.
• The growth of the fast food industry has made an
abundance of high fat, inexpensive meals widely
available, resulting in a shift in stable المستقرة foods from
low quality staples (corn) to high quality refined staples
(processed rice, wheat).
24.
Cultural factors (1)
Culturalfactors (1):
:
• The cultural practice of placing young women in ‘fattening
rooms’ for months before marriage or after childbirth. In
fattening تسمين rooms, the daily routine was to:
1.
1. Sleep ,
Sleep ,
2.
2. Eat and
Eat and
3.
3. Grow fat
Grow fat. The women spent their time resting like
beached whales and gorging التهام on a high-fat, high-
calorie diets. This practice has greatly reduced in recent
years in south-eastern parts of Nigeria.
• In certain cultures of the world ‘big is beautiful’. Obesity
was a sign of wealth and well-being in the past and still is
in many parts of Africa.
25.
Cultural factors(2)
Cultural factors(2):
:
•In contrast to many Western cultures where thin is, in
many culture-conscious people in these parts hailed
رحبت, a woman's rotundity تكور as a sign of good health,
prosperity ازدهار and allure اغراء.
• The Japanese sumo wrestlers
The Japanese sumo wrestlers مصارعون
مصارعون are well known
are well known
obese individuals. They achieve their big size from:
obese individuals. They achieve their big size from:
• An elaborateمتقن rice- based diet,
• Fat-rich stew حساءand
• Lots of sleep.
26.
Psychological and medicalfactors
Psychological and medical factors:/1
:/1
1.
1. Psychological factors
Psychological factors are known to influence
eating habits. Many people eat in response to
negative emotions, such as anger, sadness or
boredom .
2.
2. Metabolic and organic factors
Metabolic and organic factors including drug
drug
therapies
therapies have been associated with obesity as
metabolic rate slows down, the tendency to gain
weight increases. Slow metabolic rate
Slow metabolic rate is found
with reduced physical activity
reduced physical activity, advancing age, and
in females
females compared to males
27.
Psychological and medicalfactors
Psychological and medical factors:/
:/ 2
2
3.
3. Certain medical conditions
Certain medical conditions are associated with
are associated with
obesity
obesity: depression
depression, hypothyroidism, pituitary
tumors, cerebral diseases
cerebral diseases including infections
infections,
hydrocephalus, as well as certain chromosomal
chromosomal
anomalies
anomalies – Down syndrome.
4.
4. Drugs that can cause weight gain include
Drugs that can cause weight gain include:
corticosteroids, anti-depressant drugs
anti-depressant drugs,
antipsychotics, oral contraceptive
oral contraceptive and
progestagenic compounds, hypoglycemic
hypoglycemic
agents
agents, insulin, antihistamines
antihistamines,
28.
Question 5:
Question 5:
Whichof the following factors will increase the
risk of obesity in an individual? Write “T” or
“F”.:
A. Physical inactivity
B. Consumption of fast foods
C. Psychological depression
D. Normal sized parents
E. Hyperthyroidism
29.
Question 6:
Question 6:
•Several factors play a role in the pathogenesis of
obesity. What risk factors match the following
pictures?: a)? c)? b)?.
30.
Obesity is adisease. /2
Obesity is a disease. /2nd
nd
part
part
• Associations with obesity are proteanمتقلبة .
Medical associations of obesity:
Medical associations of obesity:
1. Hypertension and
2. Type II diabetes
3. Coronary artery disease, and
4. Stroke,
5. Cancers and
6. Reproductive abnormalities
7. Psychological complications including eating disorders,
8. Respiratory and other complications.
Effects of obesity
Effects of obesity
31.
Obesity - aknown risk factor for several life-
Obesity - a known risk factor for several life-
threatening medical conditions
threatening medical conditions
(1)
(1) Diabetes Mellitus (DM) :
:
• The relation between obesity and type II diabetes
(non-insulin dependent diabetes) has been
established since the 1970s excess. Fat deposits in
Fat deposits in
obesity is associated with:
obesity is associated with:
1. Insulin resistance,
2. Glucose intolerance and
3. Premature type II diabetes.
32.
(1)
(1) Diabetes Mellitus(DM):/2
:/2
• 90% of patients with type II diabetes have BMI
higher than 23
23kg/m2
• The risk of type II DM is greatly increased where
The risk of type II DM is greatly increased where
there is:
there is:
A.A history of early weight gain (childhood
obesity),
B.Android obesity (The apple shape)
The apple shape),
C.Positive family history of DM, and
D.Maternal history of gestational DM.
33.
Obesity - aknown risk factor for several life-
Obesity - a known risk factor for several life-
threatening medical conditions
threatening medical conditions
(2) Coronary artery disease and stroke
(2) Coronary artery disease and stroke:
• The effect of obesity on cardiac function is thought
The effect of obesity on cardiac function is thought
to be due to a combination of:
to be due to a combination of:
1. Hypertension,
2. Diabetes mellitus,
3. Dyslipidaemia and
4. Increased fat mass
• The risk increases as BMI values exceed 21
21.0
kg/m2. Studies show that heart failure in 14%
women and 11% men is due to obesity
34.
(3)Cancers:
(3)Cancers:
• The riskfor cancers is more among the obese
than the non-obese population estimates
non-obese population estimates
indicate that overweight and inactivity account
indicate that overweight and inactivity account
for a quarter to a third of cancers of the
for a quarter to a third of cancers of the:
1. Breast,
2. Colon,
3. Endometrium,
4. Kidney and
5. Esophagus
35.
(4)Psychological features ofobesity:
• In US women obesity increases the risk of being
In US women obesity increases the risk of being
diagnosed with:
diagnosed with:
1. Major depression by 37%
2. Low self esteem,
3. Anxiety,قلق
4. Depression and
5. Obsessive االستحواذيbehaviors are common among
obese individuals especially women
Obesity and depression are linked closely with two
Obesity and depression are linked closely with two
eating disorders
eating disorders:
A. Night eating syndrome and
B. Bingeافراط eating disorder (including bulimiaالنهم
nervosa).
These need early recognition and early psychotherapy
36.
Other effects ofobesity (2):
1.
1. Obesity has serious deleterious effects on quality
Obesity has serious deleterious effects on quality
of life.
of life.
2. There is the social stigma associated with obesity, 20% of obese
people are less likely to marry than their thinner counterparts
3. The annual household income of obese people is nearly $7,000 less
than that of thinner people
4. An obese person is 10% more likely to live a life of poverty
5.
5. With obesity there is:
With obesity there is:
Restricted activity,
Exercise intolerance,
Pain,
Worry,
Low self esteem, and
Depression
37.
Question 7
Question 7
Whichof the following are recognized
Which of the following are recognized
associations of obesity. Write “T” or “F”
associations of obesity. Write “T” or “F”:
:
a) Hypertension
b) Type 1 diabetes
c) Osteoarthritis
d) Ovarian cancers
e) Coronary heart disease
38.
What is childhoodobesity ?
What is childhood obesity ?/1
/1
Defining childhood obesity : Obesity in childhood
has reached epidemic levels.
• In the US, it is the most common nutritional
disorder in children.
• Developing countries are also affected as the
prevalence rises among children of urban dwellers
who emulate يحاكيthe ‘affluent western lifestyle’
39.
What is childhoodobesity ?
What is childhood obesity ?/2
/2
As in adults, the WHO uses the body mass index (BMI) as
As in adults, the WHO uses the body mass index (BMI) as
the standard definition of obesity in children.
the standard definition of obesity in children.
BMI is calculated with the same formula for children
and adults, but the results are interpreted differently:
but the results are interpreted differently:
BMI for children, also referred to as BMI-for-age, is
gender and age specific
BMI changes dramatically with age in children as body
fat changes with growth, and between girls and boys
with maturity
BMI-for-age, gender specific growth charts used for
children and teens 2 – 20 years of age.
40.
Defining childhood obesity:
Definingchildhood obesity:
• BMI-for-Age is used for children and teens because
of their rate of growth and development.
• It is a useful tool because:
It is a useful tool because:
A. BMI-for-age in children and adolescents compares
well to laboratory measures of body fat
B. BMI-for-age can be used to track تعقيبbody size
throughout life
In children, obesity is defined as
In children, obesity is defined as a BMI greater than
the 95th
95th percentile for age
o while overweight
overweight is a BMI greater than the 85th
85th
percentile for age till the 95th
95th percentile for age
41.
Risk factors forchildhood obesity/1
Risk factors for childhood obesity/1:
:
1. Obesity in one or both parents
2. Infants of diabetic mothers
3. Children from single parent families
4. Families with fewer children and
5. Higher birth weight
42.
Risk factors forchildhood obesity/2
Risk factors for childhood obesity/2:
:
6. Rapid growth during infancy are associated
with an increased prevalence of obesity
7. Formula feeding during infancy
(Breast feeding in women who didn't smoke
(Breast feeding in women who didn't smoke
during pregnancy [
during pregnancy [but not in women who
but not in women who
smoked during pregnancy]
smoked during pregnancy] was significantly
was significantly
associated with a reduced risk of obesity)
associated with a reduced risk of obesity)
43.
Risk factors forchildhood obesity
Risk factors for childhood obesity
• Sedentary lifestyle
Sedentary lifestyle – increase TV viewing,
computer games
computer games, car rides, including a reduction in
reduction in
number of mandatory physical education classes
number of mandatory physical education classes in
schools especially in the US
• Increase consumption
Increase consumption of sugar sweetened drinks,
soda
soda, snacks, energy dense fast food
energy dense fast food in large
portions.
44.
The relationship betweenchildhood and adult
The relationship between childhood and adult
obesity
obesity
• Born in the 60’s with a birth weight of 2.7kg (normal
weight), she quickly became plump
plump in infancy. Neither
parent was overweight (father 72.6kg and1.72m; mother
50.8kg and 1.52m) From the age of 7, she was significantly
From the age of 7, she was significantly
heavier than her peers
heavier than her peers. In her early teens, she “weighed
88.9kg” and was advised by her pediatrician to join a
slimming club. The weight gain persisted till adulthood
The weight gain persisted till adulthood.
She is currently on nine different medications for obesity
related problems
• bridesmaid وصفat wedding-Married at age 40 weight -
178 kg, Height - 1.65m, BMI
BMI = 66 kg/m2
45.
The relationship betweenchildhood and adult
The relationship between childhood and adult
obesity
obesity
• Now that you have read
this story, list 5
obesity-associated
problems that may
occur in this woman.
Mrs. S. actually
actually
developed:
developed:
1. hypertension
2. type II diabetes
3. hypothyroidism
4. menorrhagia
5. recurrent cellulitis Other
Other
possible problems include
possible problems include :
6. osteoarthritis
7. stroke
8. metabolic syndrome
9. coronary heart disease
10.menstrual disorders
11.psychological disorders
12.cancers – ovarian
ovarian, endometrial,
breast, cervical, prostate
prostate
46.
Question 8:
Question 8:
•The following are statements about childhood obesity.
Write “T” or “F”.:
a) Obesity is not a problem in children
b) BMI-for-age is used for children and teens because of their
rate of growth and development
c) The use of BMI to define obesity doesn’t depend on gender
d) BMI-for-age in children and adolescents compares well to
laboratory measures of body fat
e) The longer a child remains obese beyond age 3 years, the
more likely that the obesity will persist into adulthood
47.
Management of obesity/1
Managementof obesity/1:
:
Effective management of obesity requires long-term
Effective management of obesity requires long-term
strategies and an integrated, multi-disciplinary approach
strategies and an integrated, multi-disciplinary approach
that includes:
that includes:
1. Community-based support for behavioral modification
including: die
diet and exercise.
exercise.
2. Research over the last decade indicates that a 5-10%
5-10%
reduction in body weight
reduction in body weight is sufficient to significantly
improve medical conditions associated with obesity,
improve medical conditions associated with obesity,
such as:
such as:
Hypertension
Hypertension,
Diabetes mellitus, and
Elevated cholesterol levels.
48.
Management of obesity/2
Managementof obesity/2:
:
Currently there is lack of evidence of effective
Currently there is lack of evidence of effective
programmes for integrated management of
programmes for integrated management of
obesity. But the following management options
obesity. But the following management options
for the management of obesity exist:
for the management of obesity exist:
A. Dietary modification
B. Behavioral modification
C. Physical activity
D. Pharmacotherapy
E. Surgery
49.
Management of obesity/3
Managementof obesity/3:
:
As always, “prevention is better than cure”.
As always, “prevention is better than cure”.
1. Recently the UK government has set a target
to halt يوقف the rise in obesity in children
aged ≤11 by 2020.
2. Strategies for the prevention of childhood and
adult obesity may need to address factors
during or before infancy that are related to
infant growth.
50.
Management options (1):
•Dietary modification the most common and
Dietary modification the most common and
conservative treatment for obesity utilizes:
conservative treatment for obesity utilizes:
1. A nutritionally balanced diet,
2. Low calorie diet,
3. Diet must
must include more fruits
fruits and vegetables
vegetables,
nuts
nuts, whole grains and exclude
exclude fatty
fatty and sugary
sugary
foods
4. Weight-loss programs recommend diets
consisting of 1,200 to 1,500 calories per day,
calories per day,
51.
The calories usuallyin the following proportions:
The calories usually in the following proportions:
A. 60 % carbohydrate,
B. 30 % fat, and
C. 10 % protein.
Individuals must be carefully screened and medically
medically
supervised
supervised while on the diet (the degree of weight loss
being dependent on individuals ability to adhere to
dietary recommendations)
Studies have shown that meal replacements
Studies have shown that meal replacements بدائل
بدائل are
often more effective than very low calories diets,
resulting in an increase in the amount of initial weight
loss and enabling dieters to maintain their weight loss
52.
Management options (2)
Managementoptions (2) Pharmacotherapy
Pharmacotherapy:
• It is recommended that anti-obesity drugs be
It is recommended that anti-obesity drugs be
used only
used only in:
1. Individuals aged 18-75yrs with a BMI of
30kg/m2 or more.
2. Individuals with a BMI of ≥27kg/m2 with
existing risk factors such as diabetes, cardiac
disease, obstructive sleep apnea or hypertension.
3. Individuals with a BMI of >30kg/m2, in whom
at least 3 months of managed care (supervised
supervised
diet
diet, exercise
exercise, and behavior modification
behavior modification) fails to
lead to significant reduction in weight.
53.
Two drugs havebeen licensed for use in the
Two drugs have been licensed for use in the
treatment of obesity:
treatment of obesity:
• Orlistat
Orlistat - prevents fat digestion and absorption
by binding to gastrointestinal lipases; useful for
those with a high intake of fat.
• Sibutramine
Sibutramine - reduces appetite and increases
thermogenesis; recommended for those who
cannot control their appetite.
These drugs should not be used as sole therapy
These drugs should not be used as sole therapy
for obesity.
for obesity.
54.
Their use requiresstrict regular monitoring and
Their use requires strict regular monitoring and
must be discontinued if
must be discontinued if
A.
A. weight loss is
weight loss is <5% after 12 weeks of use or
B. weight gain recurs while on the drugs
• Anti-obesity drug treatment should not be used
beyond a year
a year and
• Never beyond two years
two years as few studies have
examined the consequences of their long-term
use
• Gradual reversal of weight loss is known to
occur on stopping pharmacotherapy
55.
Question 9:
Question 9:
Markthe following statements as either True or False:
A. Obesity management requires an integrated multi-
disciplinary approach
B. Regular exercise is the single best predictor for achieving
long-term weight control
C. Diet must exclude more fruit and vegetables, nuts, whole
grains and include fatty and sugary foods
D. The criteria for use of pharmacotherapy is a BMI > 20
kg/m2 with persistent co-morbidity
E. A 5-10% reduction in body weight is sufficient to
significantly improve medical conditions associated with
obesity
56.
What Have ILearnt about Obesity? (1)
What Have I Learnt about Obesity? (1):
:
• Obesity is the excessive accumulation of body fat, best
defined by the Body Mass Index (or Quetelet's Index).
• BMI is the universal and convenient measure of obesity.
• It is calculated as weight divided by height squared (kg/m2).
• The BMI-for-age is used to assess obesity in children.
• In adults (age 18years and > 30 kg/m2,), obesity is
defined by a BMI, while of overweight by a BMI between
25 and 29.9 kg/m2.
• A child with a BMI-for-age >95th percentile is obese while
one with a BMI-for-age >85th percentile is overweight.
57.
• The longera child remains obese beyond age 3 years
age 3 years, the
more likely that the obesity will persist into adulthood
persist into adulthood. 30%
30%
of obese children
obese children are also obese as adults. 70% obese
70% obese
adolescents
adolescents end up as obese adults
obese adults.
• Obesity is believed to result from a complex interplay of
several factors; genetic
genetic, environmental (lifestyle
lifestyle and
dietary
dietary), cultural, socio-economic
socio-economic, psychological and
medical
medical conditions.
• Obesity is a known risk factor for several life-threatening,
chronic medical and metabolic conditions: hypertension
hypertension,
coronary artery disease, stroke
stroke, type II diabetes, cancers
cancers.
• A 5 - 10% reduction
5 - 10% reduction in body weight has been shown to
significantly improve medical conditions
medical conditions associated with
obesity.
58.
What Have ILearnt about Obesity? (2)
What Have I Learnt about Obesity? (2):
:
• Obesity has reached epidemic proportions in several
developed countries of the world and is also creeping up in
urban cities of the underdeveloped world.
• Globally, there are more than 1.1 billion overweight adults,
and at least 312 million of them are clinically obese.
• 10% of all children worldwide are either overweight or
obese, while 17.6 million children under the <5y are
estimated to be overweight.
• Rapid urbanization and economic development have led to
changing lifestyles and diets across the world which
promote excessive weight gain.
• An increasing incidence of obesity is also being seen in the
poor, developing countries of the world
• Increase body weight is now the sixth
sixth most important risk
factor contributing to the overall burden of disease
worldwide