This document provides a guide for evaluating and treating patients presenting with acute abdominal pain. It outlines a systematic approach including: 1. Performing a thorough history and physical exam, assessing ABCDEs and looking for signs of MI, DKA, or instability. 2. Ordering initial tests like EKG, ABG, US, DRE, glucometry, and guaiac to help localize or characterize the pain. 3. Considering various differential diagnoses depending on localized or diffuse pain patterns, examination findings, and initial test results. These include conditions like ruptured ectopic pregnancy, mesenteric ischemia, or pancreatitis. 4. Consulting specialists as needed and considering imaging tests or surgical consultation to establish