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@ IJTSRD | Available Online @ www.ijtsrd.com
ISSN No: 2456
International
Research
A Heart Disease Prediction Model
K. Sandhya Rani
Asst. Prof, Dhanekula Institute of
Engineering and Technology,
Ganguru, Vijayawada, Andhra
Pradesh, India
Dhanekula Institute of
ABSTRACT
The early prognosis of cardiovascular diseases can aid
in making decisions to lifestyle changes in high risk
patients and in turn reduce their complications.
Research has attempted to pinpoint the most
influential factors of heart disease as well as
accurately predict the overall risk using homogenous
data mining techniques. Recent research has delved
into amalgamating these techniques using approaches
such as hybrid data mining algorithms. This paper
proposes a rule based model to compare the
accuracies of applying rules to the individual results
of logistic regression on the Cleveland Heart Disease
Database in order to present an accurate model of
predicting heart disease.
KEYWORDS: heart disease prediction, logistic
regression, Cleveland heart disease data base
INTRODUCTION
This paper analyzes the heart disease predictions
using classification algorithms. These hidden patterns
can be used for health diagnosis in medicinal data.
Data mining technology afford an effective approach
to latest and indefinite patterns in the data. The
information which is identified can be used by the
healthcare administrators to get better services. Heart
disease was the most important reason of victims in
the countries like India, United States. Data mining
techniques like Association Rule Mining, Clustering,
Classification algorithms such as Decision
algorithm.
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018
ISSN No: 2456 - 6470 | www.ijtsrd.com | Volume
International Journal of Trend in Scientific
Research and Development (IJTSRD)
International Open Access Journal
A Heart Disease Prediction Model using Logistic Regression
M. Sai Manoj
Dhanekula Institute of Engineering
and Technology,
Ganguru, Vijayawada,
Andhra Pradesh, India
G.
Dhanekula Institute of
and
Ganguru,
Andhra Pradesh
The early prognosis of cardiovascular diseases can aid
in making decisions to lifestyle changes in high risk
patients and in turn reduce their complications.
Research has attempted to pinpoint the most
fluential factors of heart disease as well as
accurately predict the overall risk using homogenous
data mining techniques. Recent research has delved
into amalgamating these techniques using approaches
such as hybrid data mining algorithms. This paper
oses a rule based model to compare the
accuracies of applying rules to the individual results
of logistic regression on the Cleveland Heart Disease
Database in order to present an accurate model of
heart disease prediction, logistic
regression, Cleveland heart disease data base
This paper analyzes the heart disease predictions
classification algorithms. These hidden patterns
can be used for health diagnosis in medicinal data.
Data mining technology afford an effective approach
to latest and indefinite patterns in the data. The
information which is identified can be used by the
ealthcare administrators to get better services. Heart
disease was the most important reason of victims in
the countries like India, United States. Data mining
techniques like Association Rule Mining, Clustering,
Classification algorithms such as Decision tree, C4.5
The heart disease database is pre
the mining process more efficient. The
data is classified with Regression
DATA DESCRIPTION
The dataset consists of 15 types of
the table 1
All these attributes are considered to predict the heart
disease, among them age and the sex are fixed
attributes and all the other are modifiable attributes.
This dataset is collected from the Cleveland heart
disease dataset so that we can give
input to our study. After the dataset is given input to
the study dataset undergo clustering and
classification. We use logistic regression for the
processing of the dataset so that the outlier are
detected and eliminated then it wil
and accurate to predict the disease. The prediction is
Apr 2018 Page: 1463
6470 | www.ijtsrd.com | Volume - 2 | Issue – 3
Scientific
(IJTSRD)
International Open Access Journal
sing Logistic Regression
G. Suguna Mani
Dhanekula Institute of Engineering
and Technology,
Ganguru, Vijayawada,
Andhra Pradesh, India
pre-processed to make
the mining process more efficient. The pre-processed
data is classified with Regression.
of 15 types of attributes listed in
All these attributes are considered to predict the heart
among them age and the sex are fixed
attributes and all the other are modifiable attributes.
This dataset is collected from the Cleveland heart
so that we can give this dataset as the
input to our study. After the dataset is given input to
the study dataset undergo clustering and
classification. We use logistic regression for the pre-
of the dataset so that the outlier are
detected and eliminated then it will be more efficient
and accurate to predict the disease. The prediction is
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018 Page: 1464
categorized into two states one is detected and the
other one is not detected.
PROPOSED SYSTEM
This project analyzes the heart disease predictions
using classification algorithms. These hidden patterns
can be used for health diagnosis in medicinal data.
Data mining technology afford an effective approach
to latest and indefinite patterns in the data. The
information which is identified can be used by the
healthcare administrators to get better services. Heart
disease was the most important reason of victims in
the countries like India, United States. Data mining
techniques like Association Rule Mining, Clustering,
Classification algorithms such as Decision tree, C4.5
algorithm.
The heart disease database is pre-processed to make
the mining process more efficient. The pre-processed
data is classified with Regression
The term regression can be defined as the measuring
and analyzing the relation between one or more
independent variable and dependent variable.
Regression can be defined by two categories; they are
linear regression and logistic regression.
Logistic regression is a generalized by linear
regression. It is mainly used for estimating binary or
multi-class dependent variables and the response
variable is discrete, it cannot be modeled directly by
linear regression i.e. discrete variable changed into
continuous value.
Logistic regression basically is used to classify the
low dimensional data having nonlinear boundaries. It
also provides the difference in the percentage of
dependent variable and provides the rank of
individual variable according to its importance.
So, the main motto of Logistic regression is to
determine the result of each variable correctly
Logistic regression is also known as logistic model/
logit model that provide categorical variable for target
variable with two categories such as light or dark,
slim/ healthy.
In the following example there are two predictor
variables: AGE and SMOKING. The dependent
variable, or response variable is OUTCOME. The
dependent variable OUTCOME is coded 0 (negative)
and 1 (positive).
Algorithm for logistic regression
1. Suppose we represent the hypothesis itself as a
logistic function of a linear combination of inputs:
h(x)=1 / 1 + exp(wTx) This is also known as a
sigmoid neuron.
2. Suppose we interpret h(x) as P(y=1|x)
3. Then the log-odds ratio, ln
(P(y=1|x)/P(y=0|x))=wTx which is linear
4. The optimum weights will maximize the
conditional likelihood of the outputs, given the inputs.
SYSTEM REQUIREMENTS
I. HARDWARE REQUIREMENTS:-
1. System : Pentium
2. Hard Disk : 40GB
3. Ram : 512MB
II. SOFTWARE REQUIREMENTS:-
1. Operating System : Windows
2. Coding Language : JAVA
3. Data Base : MYSQL
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018 Page: 1465
FLOW CHART
flow chart diagrams used for our study
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
RESULT
In this way the heart disease is predicted accurately
and easily by using the logistic regression and above
flowchart’s. Result of the study contains 2 variables
one is detected and other is not detected.
CONCLUSION
In conclusion, as identified through the logistic
regression, it is a more efficient than the data mining
techniques as it is combinational and more complex
models to increase the accuracy of predicting the early
onset of cardiovascular diseases. This paper proposes
a framework using combinations of support ve
machines, logistic regression, and decision trees to
arrive at an accurate prediction of heart disease. Using
the Cleveland Heart Disease database, this paper
provides guidelines to train and test the system and
thus attain the most efficient model of
rule based combinations. Further, this paper proposes
a comparative study of the multiple results, which
include sensitivity, specificity, and accuracy. In
addition, the most effective and most weighed model
can be found. Further work involves development of
the system using the mentioned methodologies and
thus training and testing the system. Future work
involves the development of a tool in such a way that
the heart disease is predicted by taking as manual
input (attributes) and by comparing those attributes to
the database and getting the result along with t
of disease of a prospective patient. The framework
can also be extended for use on other models such as
neural networks, ensemble algorithms, etc.
Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018
disease is predicted accurately
and easily by using the logistic regression and above
’s. Result of the study contains 2 variables
one is detected and other is not detected.
ed through the logistic
it is a more efficient than the data mining
combinational and more complex
models to increase the accuracy of predicting the early
onset of cardiovascular diseases. This paper proposes
a framework using combinations of support vector
machines, logistic regression, and decision trees to
arrive at an accurate prediction of heart disease. Using
the Cleveland Heart Disease database, this paper
provides guidelines to train and test the system and
thus attain the most efficient model of the multiple
rule based combinations. Further, this paper proposes
a comparative study of the multiple results, which
include sensitivity, specificity, and accuracy. In
addition, the most effective and most weighed model
s development of
the system using the mentioned methodologies and
the system. Future work
s the development of a tool in such a way that
by taking as manual
those attributes to
the database and getting the result along with the risk
of disease of a prospective patient. The framework
can also be extended for use on other models such as
neural networks, ensemble algorithms, etc.
REFERENCES
1) Mackay,J., Mensah,G. 2004 “Atlas of Heart Disease
and Stroke” Nonserial Publication, ISBN
139789241562768 ISBN-10 9241562765.
2) Robert Detrano 1989 “Cleveland Heart Disease
Database” V.A. Medical Center, Long Beach and
Cleveland Clinic Foundation.
3) Yanwei Xing, Jie Wang and Zhiho
Gao 2007 “Combination data mining methods with
new medical data to predicting outcome of Coronary
Heart Disease” Convergence Information
Technology, 2007. International Conference
November 2007, pp 868-872.
4) Jianxin Chen, Guangcheng Xi, Yan
Chen, and Jie Wang 2007 “Predicting Syndrome by
NEI Specifications: A Comparison of Five Data
Mining Algorithms in Coronary Heart Disease” Life
System Modeling and Simulation Lecture Notes in
Computer Science, pp 129
5) Jyoti Soni, Ujma Ansari, Dipesh Sharma 2011
“Predictive Data Mining for Medical Diagnosis: An
Overview of Heart Disease Prediction” International
Journal of Computer Applications, doi 10.5120/2237
2860.
6) Mai Shouman, Tim Turner, Rob Stocker 2012 “Using
Data Mining Techniques In Heart Disease Diagnoses
And Treatment“ Electronics, Communications and
Computers (JECECC), 2012 Japan
March 2012, pp 173-177.
7) Robert Detrano, Andras Janosi, Walter Steinbrunn,
Matthias Pfisterer, Johann
Sandhu, Kern H. Guppy, Stella Lee, Victor Froelicher
1989 “International application of a new probability
algorithm for the diagnosis of coronary artery
disease” The American Journal of Cardiology, pp
304-310.15
8) ] Polat, K., S. Sahan, and S. Gunes 2007 “Automatic
detection of heart disease using an artificial immune
recognition system (AIRS) with fuzzy resource
allocation mechanism and k
based weighting preprocessing” Expert Systems with
Applications 2007, pp 625
9) Ozsen, S., Gunes, S. 2009
genetic algorithms for attribute weighted artificial
immune system (AWAIS) and its application to heart
disease and liver disorders problems” Expert Systems
with Applications, pp 386-
10) Resul Das, Ibrahim Turkoglub, and Abdulkadi
Sengurb 2009 “Effective diagnosis of heart disease
through neural networks ensembles” Expert Systems
with Applications, pp 7675
Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Apr 2018 Page: 1466
2004 “Atlas of Heart Disease
and Stroke” Nonserial Publication, ISBN-
10 9241562765.
Robert Detrano 1989 “Cleveland Heart Disease
Database” V.A. Medical Center, Long Beach and
Cleveland Clinic Foundation.
Yanwei Xing, Jie Wang and Zhihong Zhao Yonghong
Gao 2007 “Combination data mining methods with
new medical data to predicting outcome of Coronary
Heart Disease” Convergence Information
Technology, 2007. International Conference
872.
Jianxin Chen, Guangcheng Xi, Yanwei Xing, Jing
Chen, and Jie Wang 2007 “Predicting Syndrome by
NEI Specifications: A Comparison of Five Data
Mining Algorithms in Coronary Heart Disease” Life
System Modeling and Simulation Lecture Notes in
Computer Science, pp 129-135.
sari, Dipesh Sharma 2011
“Predictive Data Mining for Medical Diagnosis: An
Overview of Heart Disease Prediction” International
Journal of Computer Applications, doi 10.5120/2237-
Mai Shouman, Tim Turner, Rob Stocker 2012 “Using
In Heart Disease Diagnoses
And Treatment“ Electronics, Communications and
Computers (JECECC), 2012 Japan-Egypt Conference
Robert Detrano, Andras Janosi, Walter Steinbrunn,
Matthias Pfisterer, Johann-Jakob Schmid, Sarbjit
rn H. Guppy, Stella Lee, Victor Froelicher
1989 “International application of a new probability
algorithm for the diagnosis of coronary artery
disease” The American Journal of Cardiology, pp
] Polat, K., S. Sahan, and S. Gunes 2007 “Automatic
tection of heart disease using an artificial immune
recognition system (AIRS) with fuzzy resource
allocation mechanism and k-nn (nearest neighbour)
based weighting preprocessing” Expert Systems with
Applications 2007, pp 625-631.
Ozsen, S., Gunes, S. 2009 “Attribute weighting via
genetic algorithms for attribute weighted artificial
immune system (AWAIS) and its application to heart
disease and liver disorders problems” Expert Systems
-392.
Resul Das, Ibrahim Turkoglub, and Abdulkadir
Sengurb 2009 “Effective diagnosis of heart disease
through neural networks ensembles” Expert Systems
with Applications, pp 7675–7680.

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A Heart Disease Prediction Model using Logistic Regression

  • 1. @ IJTSRD | Available Online @ www.ijtsrd.com ISSN No: 2456 International Research A Heart Disease Prediction Model K. Sandhya Rani Asst. Prof, Dhanekula Institute of Engineering and Technology, Ganguru, Vijayawada, Andhra Pradesh, India Dhanekula Institute of ABSTRACT The early prognosis of cardiovascular diseases can aid in making decisions to lifestyle changes in high risk patients and in turn reduce their complications. Research has attempted to pinpoint the most influential factors of heart disease as well as accurately predict the overall risk using homogenous data mining techniques. Recent research has delved into amalgamating these techniques using approaches such as hybrid data mining algorithms. This paper proposes a rule based model to compare the accuracies of applying rules to the individual results of logistic regression on the Cleveland Heart Disease Database in order to present an accurate model of predicting heart disease. KEYWORDS: heart disease prediction, logistic regression, Cleveland heart disease data base INTRODUCTION This paper analyzes the heart disease predictions using classification algorithms. These hidden patterns can be used for health diagnosis in medicinal data. Data mining technology afford an effective approach to latest and indefinite patterns in the data. The information which is identified can be used by the healthcare administrators to get better services. Heart disease was the most important reason of victims in the countries like India, United States. Data mining techniques like Association Rule Mining, Clustering, Classification algorithms such as Decision algorithm. @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018 ISSN No: 2456 - 6470 | www.ijtsrd.com | Volume International Journal of Trend in Scientific Research and Development (IJTSRD) International Open Access Journal A Heart Disease Prediction Model using Logistic Regression M. Sai Manoj Dhanekula Institute of Engineering and Technology, Ganguru, Vijayawada, Andhra Pradesh, India G. Dhanekula Institute of and Ganguru, Andhra Pradesh The early prognosis of cardiovascular diseases can aid in making decisions to lifestyle changes in high risk patients and in turn reduce their complications. Research has attempted to pinpoint the most fluential factors of heart disease as well as accurately predict the overall risk using homogenous data mining techniques. Recent research has delved into amalgamating these techniques using approaches such as hybrid data mining algorithms. This paper oses a rule based model to compare the accuracies of applying rules to the individual results of logistic regression on the Cleveland Heart Disease Database in order to present an accurate model of heart disease prediction, logistic regression, Cleveland heart disease data base This paper analyzes the heart disease predictions classification algorithms. These hidden patterns can be used for health diagnosis in medicinal data. Data mining technology afford an effective approach to latest and indefinite patterns in the data. The information which is identified can be used by the ealthcare administrators to get better services. Heart disease was the most important reason of victims in the countries like India, United States. Data mining techniques like Association Rule Mining, Clustering, Classification algorithms such as Decision tree, C4.5 The heart disease database is pre the mining process more efficient. The data is classified with Regression DATA DESCRIPTION The dataset consists of 15 types of the table 1 All these attributes are considered to predict the heart disease, among them age and the sex are fixed attributes and all the other are modifiable attributes. This dataset is collected from the Cleveland heart disease dataset so that we can give input to our study. After the dataset is given input to the study dataset undergo clustering and classification. We use logistic regression for the processing of the dataset so that the outlier are detected and eliminated then it wil and accurate to predict the disease. The prediction is Apr 2018 Page: 1463 6470 | www.ijtsrd.com | Volume - 2 | Issue – 3 Scientific (IJTSRD) International Open Access Journal sing Logistic Regression G. Suguna Mani Dhanekula Institute of Engineering and Technology, Ganguru, Vijayawada, Andhra Pradesh, India pre-processed to make the mining process more efficient. The pre-processed data is classified with Regression. of 15 types of attributes listed in All these attributes are considered to predict the heart among them age and the sex are fixed attributes and all the other are modifiable attributes. This dataset is collected from the Cleveland heart so that we can give this dataset as the input to our study. After the dataset is given input to the study dataset undergo clustering and classification. We use logistic regression for the pre- of the dataset so that the outlier are detected and eliminated then it will be more efficient and accurate to predict the disease. The prediction is
  • 2. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018 Page: 1464 categorized into two states one is detected and the other one is not detected. PROPOSED SYSTEM This project analyzes the heart disease predictions using classification algorithms. These hidden patterns can be used for health diagnosis in medicinal data. Data mining technology afford an effective approach to latest and indefinite patterns in the data. The information which is identified can be used by the healthcare administrators to get better services. Heart disease was the most important reason of victims in the countries like India, United States. Data mining techniques like Association Rule Mining, Clustering, Classification algorithms such as Decision tree, C4.5 algorithm. The heart disease database is pre-processed to make the mining process more efficient. The pre-processed data is classified with Regression The term regression can be defined as the measuring and analyzing the relation between one or more independent variable and dependent variable. Regression can be defined by two categories; they are linear regression and logistic regression. Logistic regression is a generalized by linear regression. It is mainly used for estimating binary or multi-class dependent variables and the response variable is discrete, it cannot be modeled directly by linear regression i.e. discrete variable changed into continuous value. Logistic regression basically is used to classify the low dimensional data having nonlinear boundaries. It also provides the difference in the percentage of dependent variable and provides the rank of individual variable according to its importance. So, the main motto of Logistic regression is to determine the result of each variable correctly Logistic regression is also known as logistic model/ logit model that provide categorical variable for target variable with two categories such as light or dark, slim/ healthy. In the following example there are two predictor variables: AGE and SMOKING. The dependent variable, or response variable is OUTCOME. The dependent variable OUTCOME is coded 0 (negative) and 1 (positive). Algorithm for logistic regression 1. Suppose we represent the hypothesis itself as a logistic function of a linear combination of inputs: h(x)=1 / 1 + exp(wTx) This is also known as a sigmoid neuron. 2. Suppose we interpret h(x) as P(y=1|x) 3. Then the log-odds ratio, ln (P(y=1|x)/P(y=0|x))=wTx which is linear 4. The optimum weights will maximize the conditional likelihood of the outputs, given the inputs. SYSTEM REQUIREMENTS I. HARDWARE REQUIREMENTS:- 1. System : Pentium 2. Hard Disk : 40GB 3. Ram : 512MB II. SOFTWARE REQUIREMENTS:- 1. Operating System : Windows 2. Coding Language : JAVA 3. Data Base : MYSQL
  • 3. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018 Page: 1465 FLOW CHART flow chart diagrams used for our study
  • 4. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com RESULT In this way the heart disease is predicted accurately and easily by using the logistic regression and above flowchart’s. Result of the study contains 2 variables one is detected and other is not detected. CONCLUSION In conclusion, as identified through the logistic regression, it is a more efficient than the data mining techniques as it is combinational and more complex models to increase the accuracy of predicting the early onset of cardiovascular diseases. This paper proposes a framework using combinations of support ve machines, logistic regression, and decision trees to arrive at an accurate prediction of heart disease. Using the Cleveland Heart Disease database, this paper provides guidelines to train and test the system and thus attain the most efficient model of rule based combinations. Further, this paper proposes a comparative study of the multiple results, which include sensitivity, specificity, and accuracy. In addition, the most effective and most weighed model can be found. Further work involves development of the system using the mentioned methodologies and thus training and testing the system. Future work involves the development of a tool in such a way that the heart disease is predicted by taking as manual input (attributes) and by comparing those attributes to the database and getting the result along with t of disease of a prospective patient. The framework can also be extended for use on other models such as neural networks, ensemble algorithms, etc. Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 3 | Mar-Apr 2018 disease is predicted accurately and easily by using the logistic regression and above ’s. Result of the study contains 2 variables one is detected and other is not detected. ed through the logistic it is a more efficient than the data mining combinational and more complex models to increase the accuracy of predicting the early onset of cardiovascular diseases. This paper proposes a framework using combinations of support vector machines, logistic regression, and decision trees to arrive at an accurate prediction of heart disease. Using the Cleveland Heart Disease database, this paper provides guidelines to train and test the system and thus attain the most efficient model of the multiple rule based combinations. Further, this paper proposes a comparative study of the multiple results, which include sensitivity, specificity, and accuracy. In addition, the most effective and most weighed model s development of the system using the mentioned methodologies and the system. Future work s the development of a tool in such a way that by taking as manual those attributes to the database and getting the result along with the risk of disease of a prospective patient. The framework can also be extended for use on other models such as neural networks, ensemble algorithms, etc. REFERENCES 1) Mackay,J., Mensah,G. 2004 “Atlas of Heart Disease and Stroke” Nonserial Publication, ISBN 139789241562768 ISBN-10 9241562765. 2) Robert Detrano 1989 “Cleveland Heart Disease Database” V.A. Medical Center, Long Beach and Cleveland Clinic Foundation. 3) Yanwei Xing, Jie Wang and Zhiho Gao 2007 “Combination data mining methods with new medical data to predicting outcome of Coronary Heart Disease” Convergence Information Technology, 2007. International Conference November 2007, pp 868-872. 4) Jianxin Chen, Guangcheng Xi, Yan Chen, and Jie Wang 2007 “Predicting Syndrome by NEI Specifications: A Comparison of Five Data Mining Algorithms in Coronary Heart Disease” Life System Modeling and Simulation Lecture Notes in Computer Science, pp 129 5) Jyoti Soni, Ujma Ansari, Dipesh Sharma 2011 “Predictive Data Mining for Medical Diagnosis: An Overview of Heart Disease Prediction” International Journal of Computer Applications, doi 10.5120/2237 2860. 6) Mai Shouman, Tim Turner, Rob Stocker 2012 “Using Data Mining Techniques In Heart Disease Diagnoses And Treatment“ Electronics, Communications and Computers (JECECC), 2012 Japan March 2012, pp 173-177. 7) Robert Detrano, Andras Janosi, Walter Steinbrunn, Matthias Pfisterer, Johann Sandhu, Kern H. Guppy, Stella Lee, Victor Froelicher 1989 “International application of a new probability algorithm for the diagnosis of coronary artery disease” The American Journal of Cardiology, pp 304-310.15 8) ] Polat, K., S. Sahan, and S. Gunes 2007 “Automatic detection of heart disease using an artificial immune recognition system (AIRS) with fuzzy resource allocation mechanism and k based weighting preprocessing” Expert Systems with Applications 2007, pp 625 9) Ozsen, S., Gunes, S. 2009 genetic algorithms for attribute weighted artificial immune system (AWAIS) and its application to heart disease and liver disorders problems” Expert Systems with Applications, pp 386- 10) Resul Das, Ibrahim Turkoglub, and Abdulkadi Sengurb 2009 “Effective diagnosis of heart disease through neural networks ensembles” Expert Systems with Applications, pp 7675 Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Apr 2018 Page: 1466 2004 “Atlas of Heart Disease and Stroke” Nonserial Publication, ISBN- 10 9241562765. Robert Detrano 1989 “Cleveland Heart Disease Database” V.A. Medical Center, Long Beach and Cleveland Clinic Foundation. 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Guppy, Stella Lee, Victor Froelicher 1989 “International application of a new probability algorithm for the diagnosis of coronary artery disease” The American Journal of Cardiology, pp ] Polat, K., S. Sahan, and S. Gunes 2007 “Automatic tection of heart disease using an artificial immune recognition system (AIRS) with fuzzy resource allocation mechanism and k-nn (nearest neighbour) based weighting preprocessing” Expert Systems with Applications 2007, pp 625-631. Ozsen, S., Gunes, S. 2009 “Attribute weighting via genetic algorithms for attribute weighted artificial immune system (AWAIS) and its application to heart disease and liver disorders problems” Expert Systems -392. Resul Das, Ibrahim Turkoglub, and Abdulkadir Sengurb 2009 “Effective diagnosis of heart disease through neural networks ensembles” Expert Systems with Applications, pp 7675–7680.