The document provides an overview of the 888 Titrando and 890 Titrando potentiometric titration systems from Metrohm. It summarizes their key features, which include a touch control interface, intelligent dosing units and exchange units, support for automation via sample changers, and compliance with GLP/GMP standards. The systems enable potentiometric and Karl Fischer titration using intelligent electrodes and software for method development and data management.
The Titrando is an intelligent Karl Fischer titrator that provides high-level automation and data management capabilities. It offers favorites for quick method starts, intelligent dosing elements, iConnect for mobile measuring input, and compliance with GMP/GLP and FDA regulations. The Titrando integrates with tiamo control and database software to enable complete laboratory automation through parallel titration and sample changer control.
1) tiamo is Metrohm's new control and database software for titration systems and laboratory automation. It allows for titration, dosing, and complete automation of analytical workflows.
2) tiamo offers a modern user interface, powerful report generation, flexible method editor, real-time parallel titrations, client-server database, and export of data to LIMS systems.
3) As tiamo can integrate existing Titrino and new Titrando systems, it protects customers' investments while offering compatibility across different Metrohm instruments.
System suitability tests (SST) ensure that chromatography systems are operating as expected prior to sample analysis. Key parameters evaluated include column efficiency, resolution, asymmetry, retention time, capacity factor, and precision. SST solutions contain analytes of interest and closely eluting components at known levels. Acceptance criteria are established during validation. If an SST fails, the analysis is stopped and the system diagnosed before re-running the SST. SSTs help reduce unnecessary retesting of samples by identifying potential issues early.
This document discusses the use of differential scanning calorimetry (DSC) to analyze various materials including ice melting points, specific heat capacity measurements of materials, starch gelatinization and retrogradation, protein denaturation, oil and fat crystallization, gel formation and melting, glass transition temperatures, and microbial growth measurements. DSC can be used to characterize many phase transitions and thermal properties of foods, polymers, and other materials.
This document provides an overview of HPLC methodology and validation requirements. It discusses the key components of an HPLC test procedure including system suitability testing, relative response factors, and the validation parameters of specificity, linearity, accuracy, precision, LOD/LOQ, and robustness. Validation requirements depend on whether the method is compendial or non-compendial, with full validation needed for non-compendial methods. System suitability criteria and validation acceptance limits are outlined for various analytical techniques like assay, impurities testing, and dissolution.
This document discusses various concepts related to high performance liquid chromatography (HPLC) peak analysis including:
1. It describes factors that influence peak shape such as column packing, mobile phase composition, pH, and buffers which can improve peak symmetry and resolution.
2. Key parameters for characterizing chromatographic performance are discussed including retention factor (k), selectivity factor (α), plate number (N), and height equivalent of a theoretical plate (HETP).
3. Optimizing these parameters through adjusting mobile phase or column properties can enhance separation and analysis of chromatographic runs.
This document provides an overview and catalog of various accessories for dissolution testing equipment manufactured by ELECTROLAB, including vessels, baskets, paddles, cannulas, filters, and more. It describes the appropriate uses and specifications of different accessory types in accordance with USP standards. Maintenance tips are also provided to help preserve the quality and longevity of the accessories.
This document provides tips and tricks for maintaining an HPLC instrument. It discusses the benefits of instrument service plans and visually inspecting the instrument weekly. Inputs are shared from Nordic field service engineers on best practices like using certified consumables and troubleshooting from the flow path direction. Useful tools discussed include backpressure coils, syringes, and control charts in Chromeleon. Maintaining a log book and monitoring for high backpressure are also recommended.
The Titrando is an intelligent Karl Fischer titrator that provides high-level automation and data management capabilities. It offers favorites for quick method starts, intelligent dosing elements, iConnect for mobile measuring input, and compliance with GMP/GLP and FDA regulations. The Titrando integrates with tiamo control and database software to enable complete laboratory automation through parallel titration and sample changer control.
1) tiamo is Metrohm's new control and database software for titration systems and laboratory automation. It allows for titration, dosing, and complete automation of analytical workflows.
2) tiamo offers a modern user interface, powerful report generation, flexible method editor, real-time parallel titrations, client-server database, and export of data to LIMS systems.
3) As tiamo can integrate existing Titrino and new Titrando systems, it protects customers' investments while offering compatibility across different Metrohm instruments.
System suitability tests (SST) ensure that chromatography systems are operating as expected prior to sample analysis. Key parameters evaluated include column efficiency, resolution, asymmetry, retention time, capacity factor, and precision. SST solutions contain analytes of interest and closely eluting components at known levels. Acceptance criteria are established during validation. If an SST fails, the analysis is stopped and the system diagnosed before re-running the SST. SSTs help reduce unnecessary retesting of samples by identifying potential issues early.
This document discusses the use of differential scanning calorimetry (DSC) to analyze various materials including ice melting points, specific heat capacity measurements of materials, starch gelatinization and retrogradation, protein denaturation, oil and fat crystallization, gel formation and melting, glass transition temperatures, and microbial growth measurements. DSC can be used to characterize many phase transitions and thermal properties of foods, polymers, and other materials.
This document provides an overview of HPLC methodology and validation requirements. It discusses the key components of an HPLC test procedure including system suitability testing, relative response factors, and the validation parameters of specificity, linearity, accuracy, precision, LOD/LOQ, and robustness. Validation requirements depend on whether the method is compendial or non-compendial, with full validation needed for non-compendial methods. System suitability criteria and validation acceptance limits are outlined for various analytical techniques like assay, impurities testing, and dissolution.
This document discusses various concepts related to high performance liquid chromatography (HPLC) peak analysis including:
1. It describes factors that influence peak shape such as column packing, mobile phase composition, pH, and buffers which can improve peak symmetry and resolution.
2. Key parameters for characterizing chromatographic performance are discussed including retention factor (k), selectivity factor (α), plate number (N), and height equivalent of a theoretical plate (HETP).
3. Optimizing these parameters through adjusting mobile phase or column properties can enhance separation and analysis of chromatographic runs.
This document provides an overview and catalog of various accessories for dissolution testing equipment manufactured by ELECTROLAB, including vessels, baskets, paddles, cannulas, filters, and more. It describes the appropriate uses and specifications of different accessory types in accordance with USP standards. Maintenance tips are also provided to help preserve the quality and longevity of the accessories.
This document provides tips and tricks for maintaining an HPLC instrument. It discusses the benefits of instrument service plans and visually inspecting the instrument weekly. Inputs are shared from Nordic field service engineers on best practices like using certified consumables and troubleshooting from the flow path direction. Useful tools discussed include backpressure coils, syringes, and control charts in Chromeleon. Maintaining a log book and monitoring for high backpressure are also recommended.
General considerations and method development in ce,ChowdaryPavani
This document provides an overview of capillary electrophoresis (CE). It defines CE, describes its principle and instrumentation. CE involves separating components of a sample based on their differential rate of migration in an applied electric field. Key points covered include electrophoretic mobility, electroosmotic flow, sample introduction techniques, and common applications such as protein, DNA and pharmaceutical analysis. CE provides high resolution separations due to its small capillary diameter and long separation length.
This document discusses validation and calibration of HPLC systems. It defines validation as establishing that an analytical procedure meets requirements for its intended use through laboratory studies. A validation protocol outlines how validation will be conducted. Equipment validation demonstrates that equipment is suitable for use and comparable to routine equipment. Calibration involves demonstrating that an instrument produces results within specified limits compared to a reference standard. The document outlines parameters to validate like accuracy, precision, specificity, range, robustness and more. It provides details on testing these parameters and accepting calibration of modules like the pump, injector, detector and column heating.
This document provides information about different types of columns used in high performance liquid chromatography (HPLC). It discusses normal phase and reverse phase chromatography columns. It describes various column packing materials, particle sizes, dimensions, costs and specifications. It provides details on columns from several major manufacturers like Waters, Phenomenex, Agilent, GE Healthcare and others. Preparative chromatography is also briefly mentioned. Resources for further information are listed at the end.
As we all know chromatographic fingerprinting of botanicals is a quite recent concept. This presentation will help to the beginners to understand basic thories and fundamantals of thin layer chomatography. The presentation will also provide basic experiemental understanding to perfrom HPTLC fingerprinting of samples/extracts/formulations.
This document discusses the principles and applications of CHNS elemental analyzers. CHNS analyzers determine the levels of carbon, hydrogen, nitrogen, and sulfur in organic materials through combustion. Samples are burned at high temperatures, converting the elements to gases that are then detected using techniques like gas chromatography or thermal conductivity. The instruments are used widely in fields like pharmaceuticals, polymers, chemicals, foods, and oil refining to analyze sample composition and monitor processes.
Supercritical fluid chromatography uses a supercritical fluid as the mobile phase to carry samples through a chromatographic column. As analyte bands exit the column, their identities and quantities are determined by a detector. Common supercritical fluids used are gases like carbon dioxide above their critical temperature and pressure, giving them properties between liquids and gases. Separation is based on interaction between analytes and the stationary phase. SFC offers advantages over HPLC like rapid separations without organic solvents and over GC through analysis of thermally labile compounds at lower temperatures. It finds applications in areas like pharmaceuticals, polymers, foods, and enantiomer separations.
The document discusses analytical method development for HPLC. It notes that method development requires selecting requirements, instrumentation type, and why. Existing methods may be unreliable, expensive, or time-consuming, necessitating new method development. Key steps in development include defining goals, establishing sample preparation, selecting detector and mode of separation, performing preliminary separations, optimizing conditions, and validating the method. Method development is informed by factors like number of analytes, sample matrix, and analyte properties.
Development and Validation of a RP-HPLC methodUshaKhanal3
The document describes the process of developing and validating a reverse phase high performance liquid chromatography (RP-HPLC) method. It involves determining method goals and analysis requirements based on the sample properties, conducting research on existing methods, selecting an analysis technique, optimizing the separation conditions through a systematic approach, and validating the method. Key steps include choosing the detector and mobile phase, optimizing variables like column type, temperature, flow rate and solvent composition to improve resolution and separation time, and testing the method's accuracy, precision, specificity and robustness.
This document provides an electrode catalog with recommendations for which Metrosensor electrodes to use for various pH measurement and titration applications. It lists electrodes for general and specialized pH measurement in areas like water, wastewater, agriculture, food, pharmaceuticals, and more. It also lists electrodes for different types of titrations including acid/base, redox, Karl Fischer, precipitation, and complexometric titrations. The catalog provides details on each electrode model including its order number and the page in the catalog where its specifications can be found.
This document discusses the calibration of various analytical instruments used in pharmaceutical analysis. It begins with an introduction to calibration and the need for calibrating instruments. It then provides details on calibrating UV-Vis spectrophotometers, IR spectrophotometers, spectrofluorimeters, HPTLC, and gas chromatography. For each instrument, it describes the parameters checked during calibration such as wavelength accuracy, resolution, photometric accuracy, linearity, and acceptance criteria. The document aims to explain the calibration process for key analytical tools to ensure accurate measurements.
Ion pair chromatography for pharmacy studentsabhishek rai
Ion-PairChromatography
A GENERALISED OVERVIEW
Chromatography
HPLC
Reverse Phase Chromatography
Ion Pair Chromatography
Ion Pair Reagent
Mechanism of Ion Pair Chromatography
Ion Pair Wash Procedure
The auto titrator works by potentiometrically measuring the change in potential of a solution as a titrant of known concentration is dispensed. It can perform various acid-base and complexometric titrations more quickly, accurately, and precisely than classical titration methods. The Mettler Toledo T70 auto titrator model's operation involves preparing the equipment, calibrating sensors, selecting a pre-programmed method, validating the results against known standards, running the titration, and automatically printing a test report. Auto titrators are used in many industries to determine unknown concentrations of analytes like acids, bases, metals, and chemicals.
This document provides an overview of supercritical fluid chromatography (SFC). It defines SFC as using a fluid above its critical temperature and pressure that has properties of both a liquid and gas. The principle is similar to HPLC but uses compressed carbon dioxide as the mobile phase. Key aspects of SFC instrumentation discussed include pumps, injectors, columns, detectors, and use of modifiers to modify carbon dioxide polarity. Advantages of SFC include low operating temperatures and viscosities with high diffusion rates. Applications mentioned include chiral separations important for the pharmaceutical industry.
This document provides calibration procedures for various instruments used in pharmaceutical analysis. It describes calibrating a UV-Vis spectrophotometer using holmium perchlorate and potassium dichromate primary standards to control wavelength and absorbance. It also provides procedures to calibrate using potassium chloride and toluene solutions. Regular calibration is important to ensure instruments produce accurate results, and should be performed when time periods elapse, operating hours change, a new instrument is used, or observations seem questionable.
Supercritical fluid chromatography (SFC) is a combination of high performance liquid chromatography and gas chromatography that uses supercritical fluids as the mobile phase. Carbon dioxide is most commonly used as the supercritical fluid due to its low critical temperature and pressure. SFC allows for faster analysis of both volatile and non-volatile compounds compared to HPLC and GC. It has advantages over HPLC such as using non-toxic solvents and over GC in analyzing thermally labile compounds at lower temperatures. SFC finds applications in pharmaceuticals, polymers, fuels, foods and natural products.
Validation of pharaceutical water system and pure steamJp Prakash
This document discusses the validation of pharmaceutical water systems and pure steam. It covers the validation sequences of design qualification, installation qualification, operational qualification, and performance qualification. Design qualification involves validating components like piping, tanks, filters, and distillation stills. Installation qualification ensures proper installation. Performance qualification demonstrates the system can reliably produce water and steam meeting quality requirements over extended use. Validation is necessary to assure safety, efficacy and quality according to regulations.
The document summarizes the features of the Testo 176 P1 data logger. It has an internal absolute pressure sensor and can connect to two external temperature and humidity probes. It stores up to 2 million measurement values and has a battery life of up to 8 years. The data logger measures parameters like pressure, temperature, and humidity and securely stores the data. It transfers the data via USB or SD card and includes software for programming and analysis.
The highly accurate thermal hygrometer testo 645 has two probe inputs and can measure temperature, relative humidity, dewpoint and other parameters. It stores up to 3000 measurement values and allows analysis on a PC. Accessories include probes, a printer, software, and a transport case. The instrument provides precise humidity measurements up to ±1% RH.
General considerations and method development in ce,ChowdaryPavani
This document provides an overview of capillary electrophoresis (CE). It defines CE, describes its principle and instrumentation. CE involves separating components of a sample based on their differential rate of migration in an applied electric field. Key points covered include electrophoretic mobility, electroosmotic flow, sample introduction techniques, and common applications such as protein, DNA and pharmaceutical analysis. CE provides high resolution separations due to its small capillary diameter and long separation length.
This document discusses validation and calibration of HPLC systems. It defines validation as establishing that an analytical procedure meets requirements for its intended use through laboratory studies. A validation protocol outlines how validation will be conducted. Equipment validation demonstrates that equipment is suitable for use and comparable to routine equipment. Calibration involves demonstrating that an instrument produces results within specified limits compared to a reference standard. The document outlines parameters to validate like accuracy, precision, specificity, range, robustness and more. It provides details on testing these parameters and accepting calibration of modules like the pump, injector, detector and column heating.
This document provides information about different types of columns used in high performance liquid chromatography (HPLC). It discusses normal phase and reverse phase chromatography columns. It describes various column packing materials, particle sizes, dimensions, costs and specifications. It provides details on columns from several major manufacturers like Waters, Phenomenex, Agilent, GE Healthcare and others. Preparative chromatography is also briefly mentioned. Resources for further information are listed at the end.
As we all know chromatographic fingerprinting of botanicals is a quite recent concept. This presentation will help to the beginners to understand basic thories and fundamantals of thin layer chomatography. The presentation will also provide basic experiemental understanding to perfrom HPTLC fingerprinting of samples/extracts/formulations.
This document discusses the principles and applications of CHNS elemental analyzers. CHNS analyzers determine the levels of carbon, hydrogen, nitrogen, and sulfur in organic materials through combustion. Samples are burned at high temperatures, converting the elements to gases that are then detected using techniques like gas chromatography or thermal conductivity. The instruments are used widely in fields like pharmaceuticals, polymers, chemicals, foods, and oil refining to analyze sample composition and monitor processes.
Supercritical fluid chromatography uses a supercritical fluid as the mobile phase to carry samples through a chromatographic column. As analyte bands exit the column, their identities and quantities are determined by a detector. Common supercritical fluids used are gases like carbon dioxide above their critical temperature and pressure, giving them properties between liquids and gases. Separation is based on interaction between analytes and the stationary phase. SFC offers advantages over HPLC like rapid separations without organic solvents and over GC through analysis of thermally labile compounds at lower temperatures. It finds applications in areas like pharmaceuticals, polymers, foods, and enantiomer separations.
The document discusses analytical method development for HPLC. It notes that method development requires selecting requirements, instrumentation type, and why. Existing methods may be unreliable, expensive, or time-consuming, necessitating new method development. Key steps in development include defining goals, establishing sample preparation, selecting detector and mode of separation, performing preliminary separations, optimizing conditions, and validating the method. Method development is informed by factors like number of analytes, sample matrix, and analyte properties.
Development and Validation of a RP-HPLC methodUshaKhanal3
The document describes the process of developing and validating a reverse phase high performance liquid chromatography (RP-HPLC) method. It involves determining method goals and analysis requirements based on the sample properties, conducting research on existing methods, selecting an analysis technique, optimizing the separation conditions through a systematic approach, and validating the method. Key steps include choosing the detector and mobile phase, optimizing variables like column type, temperature, flow rate and solvent composition to improve resolution and separation time, and testing the method's accuracy, precision, specificity and robustness.
This document provides an electrode catalog with recommendations for which Metrosensor electrodes to use for various pH measurement and titration applications. It lists electrodes for general and specialized pH measurement in areas like water, wastewater, agriculture, food, pharmaceuticals, and more. It also lists electrodes for different types of titrations including acid/base, redox, Karl Fischer, precipitation, and complexometric titrations. The catalog provides details on each electrode model including its order number and the page in the catalog where its specifications can be found.
This document discusses the calibration of various analytical instruments used in pharmaceutical analysis. It begins with an introduction to calibration and the need for calibrating instruments. It then provides details on calibrating UV-Vis spectrophotometers, IR spectrophotometers, spectrofluorimeters, HPTLC, and gas chromatography. For each instrument, it describes the parameters checked during calibration such as wavelength accuracy, resolution, photometric accuracy, linearity, and acceptance criteria. The document aims to explain the calibration process for key analytical tools to ensure accurate measurements.
Ion pair chromatography for pharmacy studentsabhishek rai
Ion-PairChromatography
A GENERALISED OVERVIEW
Chromatography
HPLC
Reverse Phase Chromatography
Ion Pair Chromatography
Ion Pair Reagent
Mechanism of Ion Pair Chromatography
Ion Pair Wash Procedure
The auto titrator works by potentiometrically measuring the change in potential of a solution as a titrant of known concentration is dispensed. It can perform various acid-base and complexometric titrations more quickly, accurately, and precisely than classical titration methods. The Mettler Toledo T70 auto titrator model's operation involves preparing the equipment, calibrating sensors, selecting a pre-programmed method, validating the results against known standards, running the titration, and automatically printing a test report. Auto titrators are used in many industries to determine unknown concentrations of analytes like acids, bases, metals, and chemicals.
This document provides an overview of supercritical fluid chromatography (SFC). It defines SFC as using a fluid above its critical temperature and pressure that has properties of both a liquid and gas. The principle is similar to HPLC but uses compressed carbon dioxide as the mobile phase. Key aspects of SFC instrumentation discussed include pumps, injectors, columns, detectors, and use of modifiers to modify carbon dioxide polarity. Advantages of SFC include low operating temperatures and viscosities with high diffusion rates. Applications mentioned include chiral separations important for the pharmaceutical industry.
This document provides calibration procedures for various instruments used in pharmaceutical analysis. It describes calibrating a UV-Vis spectrophotometer using holmium perchlorate and potassium dichromate primary standards to control wavelength and absorbance. It also provides procedures to calibrate using potassium chloride and toluene solutions. Regular calibration is important to ensure instruments produce accurate results, and should be performed when time periods elapse, operating hours change, a new instrument is used, or observations seem questionable.
Supercritical fluid chromatography (SFC) is a combination of high performance liquid chromatography and gas chromatography that uses supercritical fluids as the mobile phase. Carbon dioxide is most commonly used as the supercritical fluid due to its low critical temperature and pressure. SFC allows for faster analysis of both volatile and non-volatile compounds compared to HPLC and GC. It has advantages over HPLC such as using non-toxic solvents and over GC in analyzing thermally labile compounds at lower temperatures. SFC finds applications in pharmaceuticals, polymers, fuels, foods and natural products.
Validation of pharaceutical water system and pure steamJp Prakash
This document discusses the validation of pharmaceutical water systems and pure steam. It covers the validation sequences of design qualification, installation qualification, operational qualification, and performance qualification. Design qualification involves validating components like piping, tanks, filters, and distillation stills. Installation qualification ensures proper installation. Performance qualification demonstrates the system can reliably produce water and steam meeting quality requirements over extended use. Validation is necessary to assure safety, efficacy and quality according to regulations.
The document summarizes the features of the Testo 176 P1 data logger. It has an internal absolute pressure sensor and can connect to two external temperature and humidity probes. It stores up to 2 million measurement values and has a battery life of up to 8 years. The data logger measures parameters like pressure, temperature, and humidity and securely stores the data. It transfers the data via USB or SD card and includes software for programming and analysis.
The highly accurate thermal hygrometer testo 645 has two probe inputs and can measure temperature, relative humidity, dewpoint and other parameters. It stores up to 3000 measurement values and allows analysis on a PC. Accessories include probes, a printer, software, and a transport case. The instrument provides precise humidity measurements up to ±1% RH.
The testo 175 T1 and testo 175 T2 are compact data loggers for monitoring refrigerated rooms and transport temperatures. They have a large 1 million measurement value memory, batteries that last up to 3 years, and an easy to read display. Data can be transferred via USB or SD card. The testo 175 T2 also has an external temperature probe connection. Both loggers are tested according to DIN EN 12830 standards for use in food safety applications.
The document describes the Ultraprobe 15,000 Touch, a handheld ultrasonic condition monitoring device. It has a touch screen interface that allows users to analyze machine conditions, review alarm groups, generate reports, and more. All inspection needs can be done with the palm-sized device, including analyzing sound and temperature readings, storing data and images, and reviewing historical records. The touch screen makes ultrasonic inspection simple via intuitive icons. The device is robust yet easy to use, suitable for many plant applications like leak detection, bearing inspection, and electrical equipment analysis.
The testo 110 is a 1-channel temperature measuring instrument that is highly accurate and universally applicable. It has an optional protective case called TopSafe that protects it from dirt, water, and impacts. Key features include a large backlit display, minimum/maximum value storage, audible alarms, accuracy of ±0.2°C from -20°C to +80°C, and certification according to EN 13485. It can be used with both wired and wireless probes for various temperature measurement applications.
The testo 175 H1 is a professional data logger for monitoring temperature and relative humidity in indoor spaces. It has a large display and memory capacity to store over 1 million measurement values. The external humidity and temperature probe reacts faster than internal sensors. The data logger runs for up to 3 years on batteries and data can be transferred via USB or SD card. It provides accurate, long-term monitoring of indoor climate to help optimize ventilation and air quality.
The TRK-1P is a new 4-in-1 instrument that combines an auto refractometer, keratometer, non-contact tonometer, and pachymeter into a compact unit. It allows for fully automated measurement of refractive error, corneal curvature, intraocular pressure, and corneal thickness. Integration with Topcon's i-base software allows captured data to be displayed, saved, and shared with other devices like phoropters.
Temperature profiling involves using multiple thermocouples connected to a product in an industrial oven to accurately log the temperature of the product over time. The Phoenix monitoring system can log temperatures from up to 20 thermocouples to determine if the heat treatment specification has been met. It provides a more accurate measurement of true product temperature than thermocouples that only measure atmosphere temperature. The profiling trials allow issues with the furnace process to be quickly resolved and provide customers assurance of consistent temperature control.
Webinar: Is your cheese at the correct temperature?Simple Hardware
Can you do hot monitoring as well?
Overview of Simple HW devices, device positioning, business logic. Description of modes.
Precision and resolution/sensors.
This document provides a specification sheet for the RTC-156/157 reference temperature calibrators from AMETEK. The calibrators offer high accuracy down to ±0.04°C, excellent stability of 0.005°C, and a wide temperature range from -30°C to 155°C. Key features include improved temperature homogeneity through an active dual-zone block, dynamic load compensation for perfect temperature uniformity, and intelligent reference sensors with stored calibration data. The calibrators communicate via USB and provide best-in-class performance according to EURAMET guidelines.
✔ The document discusses several indicator models for weighing applications including the T71, T51, CKW55, T31, and T32 series.
✔ The indicators provide high resolution weighing up to 1:500,000 and counting resolution up to 1:300,000, have large backlit displays, and operating temperature ranges of -10°C to 40°C.
✔ The indicators include features such as parts counting, checkweighing, RS232 connectivity, rechargeable batteries, and NEMA 4X/IP66 enclosures for harsh environments.
katalog produk chauvin arnoux power quality analyser CA8336, Analisa Kualitas Listrik dan Energi anda Mengunakan CA8336
Mengukur semua yang diperlukan tegangan, arus dan daya parameter untuk diagnosis penuh dari instalasi listrik. Menangkap dan merekam semua parameter, transien, alarm dan bentuk gelombang secara bersamaan. Terbukti mudah digunakan.
BlueBoxShow is a graphical software tool that allows users to easily configure the functions and parameters of iDTRONIC's BlueBox RFID devices. It connects to the devices over Ethernet or serial and displays their current settings which can be read, written, or reset to defaults. The interface provides access to configure settings for networking, antennas, RF protocols, I/O, data storage and more.
The Testo 545 lux meter measures light intensity up to 100,000 lux with 1 lux or 10 lux resolution. It stores up to 99 measurement sites and 3000 measurement values with point or timed mean calculations. Measurements can be printed on-site or analyzed using included software.
The Huminator is a small, portable climate chamber for testing materials and electronics under different humidity and temperature conditions. It can generate humidity from 5-95% RH and temperatures from 15-40°C. The built-in programming function allows automated testing by setting up to three humidity/temperature points in a sequence. It interfaces with Testo and other manufacturers' probes and data loggers for fast, easy humidity calibration on the go.
The document describes two new pH meters from Metrohm: the 780 pH Meter and the 781 pH/Ion Meter. Both meters offer high quality, easy operation, and advanced features. The 781 meter allows for both pH and ion concentration measurements using ion-selective electrodes. Both meters provide calibration functions, electrode testing, data storage, and quality control monitoring. The document compares the key specifications and capabilities of the two meters.
The document describes two pH meters, the 780 pH Meter and 781 pH/Ion Meter, produced by Metrohm. Both devices combine high quality with advanced design and offer numerous measurement and calibration functions. The 781 meter allows for additional ion concentration measurements using ion-selective electrodes. Both meters feature easy operation, automated quality control functions, and compatibility with Metrohm accessories for enhanced measurement capabilities.
The testo 922 is a 2-channel temperature measuring instrument that records temperature values from two connected probes simultaneously and displays their differential temperature. It has continuous minimum/maximum display, hold function, and can cyclically print measurements. The device is ideally suited for HVAC applications and has an IP65-rated protective cover. Optional wireless probes allow displaying a third temperature value.
The Bio-Rad T100 thermal cycler makes PCR a truly touching experience. With its compact footprint, reliable performance and easy-to-use touch screen, running PCR has never been easier.
The document provides information on various products from the AKCPro Server product catalog, including:
- Containment Mapping software that generates hot/cold aisle containment maps from floorplans and assigns sensors to racks.
- Customizable desktops that display sensor data, maps, graphs, and video feeds in predetermined or custom layouts for live or historical data review.
- Drilldown mapping desktops that allow zooming from a world view to localized floorplans to monitor multiple sites.
- Video integration that synchronizes sensor events with IP camera video for playback of critical events.
- Access control administration and door access logs/reports that can be synchronized with video.
- Tablet
Similar to 888 Titrando for Titration Applications from Metrohm (20)
Manual titration can be automated with ECO TITRATOR - save time and increase ...Metrohm India Limited
The Eco Titrator is a compact, automatic titration device that can save up to 120 titration methods. It performs titrations simply and reliably with a touch interface. It offers precise dosing, GLP-compliant documentation, and can be used for a variety of applications across industries like food and beverages, water analysis, petrochemistry, and more. Local sales organizations provide support worldwide.
Global webinar on Advanced solutions for battery material characterizationMetrohm India Limited
Webinar highlights:
-Introduction into the working principle of li-ion batteries and solid-state batteries
-Combined precision and automation: The Microcell HC setup and Metrohm Autolab devices
-The basic principle: quick and precise adjustment of the sample’s temperature by Peltier-technique
-One modular setup for different battery-related applications: determination of the conductivity of liquid and solid electrolytes, the MacMullin number of electrolyte-soaked separator foils, and the electrochemical properties of interfaces
Do you have that spark to move the world with your innovative research? Presenting IIT Bombay Metrohm Young Chemist Award 2019 – a perfect stage for all the researchers in Chemistry domain to showcase their work. Innovation in research is the essence of this contest and we recognise & award the brilliance that completes this criteria in all realms.
Application note on purified water for mammalian and bacterial cell cultureMetrohm India Limited
To achieve success in mammalian cell culture it is necessary to use extremely pure media and buffers. The use of Type I ultrapure water
to effectively eliminate the presence of biologically active species and other contaminants which could interfere with the culturing
process is essential. General laboratory grade purified water (Type II) with low levels of bacterial and organic contamination is usually
sufficiently pure for bacterial cell culture.
This document discusses quality control and analysis in power plants, focusing on three key areas:
1. Process water analysis, including parameters like pH, conductivity, hardness, and impurities. Continuous monitoring is important for processes and water chemistry.
2. Turbine oil and lubricant analysis to check properties like acid/base numbers and water content per industry standards.
3. Fuel and operating material analysis using ion chromatography to determine halogens and sulfur in samples like coal.
The document provides an overview of analytical techniques and standards for monitoring various circuits and materials in power plants to ensure safe, efficient, and reliable operations. Metrohm offers solutions for many of the described applications and parameters.
The 875 KF Gas Analyzer provides a robust solution for determining trace amounts of water in gases using automated coulometric Karl Fischer titration. It excels through its durable design and can analyze both liquid and permanent gases. The system consists of a control unit and analysis module equipped to handle gases and perform the water analysis cell fully automatically. It is ideal for routine water analysis in laboratories and industries such as refrigerants and natural gas.
Ti-Touch is a new device that aims to simplify titration experiments. It uses touchscreen technology to allow users to easily perform titrations on a mobile platform. This new device could make titration experiments more accessible and reduce errors by automating much of the process.
The 756 KF Coulometer provides automated coulometric Karl Fischer titration for determining low water contents down to the microgram range. It features a backlit LCD screen, integrated printer, methods memory, and interfaces for connecting additional devices. The instrument guarantees accurate and reproducible results for applications such as solvents, industrial products, finished products, and solids using appropriate sample introduction methods and optional accessories like the 768 KF Drying Oven.
Metrohm – customized analysis for surface finishing, Process control in elect...Metrohm India Limited
Metrohm offers analytical solutions for quality control of basic chemicals and raw materials used in surface finishing processes. Titration can be used to determine concentrations of common acids and bases. Ion chromatography can detect impurities in chemicals like hydrogen peroxide and isopropanol by using inline matrix elimination. When ultratraces need to be found, inline preconcentration can be added for high sensitivity analysis.
Metrohm offers analytical solutions for quality control of basic chemicals and raw materials used in surface finishing processes. Titration can be used to determine concentrations of common acids and bases. Ion chromatography can detect impurities in chemicals like hydrogen peroxide and isopropanol by using inline matrix elimination. When ultratraces need to be found, inline preconcentration can be added for high sensitivity analysis.
This document discusses analytical instrumentation for battery research. It summarizes several techniques for characterizing batteries including: electrochemical characterization to determine current/voltage characteristics and test charging; determination of water content which must be very low; and determination of anions and cations by ion chromatography to analyze electrolyte composition. Sophisticated instrumentation is needed for production and analysis of battery materials and cells to advance progress in battery research.
We offer you state-of-the-art instrumentation helping you to check and improve the quality of biofuels and corresponding blends as well as to comply with the standards – in your laboratory but also atline and online in the process environment
The document describes various accessories available from Metrohm for analytical instrumentation such as sample changers, thermal sample preparation devices, dosing units, filtration equipment, software, additional stations, eluent and calibration techniques, and kits for voltammetry and mercury/arsenic analysis to enhance automation and efficiency. The accessories aid in sample handling, separation, data management, and analysis across various applications like Karl Fischer titration, ion chromatography, and voltammetry. Contact information is provided for Metrohm India Limited and their local distributor.
Metrohm has taken ion chromatography to an entirely new level. We are proud to offer you the Professional IC product family – the first ion chromatography systems made up of intelligent components for:
- Anions and cations in drinking water
- Ultratrace analysis
- Ions in complex sample matrices
- Method development in R & D
Your key benefits with Metrohm ion chromatography:
* High sensitivity right down to the ppt level
* Accurate and reproducible results
* Ease of use due to
intelligent IC components
* monitoring and controlling functions
*Metrohm Inline Sample Preparation (MISP)
* Low cost of ownership
* Reliable and affordable service and support
The determination of the oxidation stability of oils and fats is the classical application for the 743 Rancimat. The resulting induction time that is determined characterizes the resistance of oils and fats to oxidation. In addition to the term «induction time», the expression Oil Stability Index (OSI) is in common use. The Rancimat method is also called the automated Swift test or accelerated oxidation test and is in general use today as an automated version of the previously used and extremely complicated Active Oxygen Method (AOM).
The document describes a pHit kit that provides an easy and gentle way to clean and regenerate pH electrodes. The kit contains solutions for cleaning the glass membrane and diaphragm without using aggressive chemicals that can damage the electrodes. Applying the pHit kit solutions is a simple process and results in considerably longer lifetimes for pH electrodes compared to conventional cleaning methods.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
How to Add Chatter in the odoo 17 ERP ModuleCeline George
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Odoo provides an option for creating a module by using a single line command. By using this command the user can make a whole structure of a module. It is very easy for a beginner to make a module. There is no need to make each file manually. This slide will show how to create a module using the scaffold method.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
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Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
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• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
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it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
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This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
3. • Touch Control with large color screen
• Titration software PC Control or tiamoTM for operation via PC
• Intuitive operation
• Intelligent Exchange Units
• Intelligent electrodes «iTrodes» for the 888 Titrando
• Potentiometric titration with the 888 Titrando
• Karl Fischer titration with the 890 Titrando
• Sample Processor control
• Lab Link for Intranet and Internet
• Online help
• Complies with FDA regulation 21 CFR Part 11
• USB interfaces for sample changer, printer, PC keyboard, barcode reader...
3
4. Overview of the 888 Titrando and
890 Titrando
888 Titrando 890 Titrando
Intelligent dosing elements for titration 1 integrated Dosimat 1 integrated Dosimat
for Exchange Unit for Exchange Unit
Additional dosing elements (dispensing only) 3 x 805 Dosimat 3 x 805 Dosimat
with Exchange Unit with Exchange Unit
3 x 800 Dosino 3 x 800 Dosino
with Dosing Unit with Dosing Unit
Intelligent Exchange Unit with integral data
Yes
chip
Increments per cylinder volume (Exchange Unit) 20’000
Measuring interface for pH, U/mV, T/°C 1 –
Intelligent electrodes «iTrodes» 1 –
Measuring input for polarizable electrodes 1
Operation, dialog Touch Control, PC Control or tiamoTM
Stirrers, titration stand 801 Stirrer (magnetic) or 802 Stirrer (rod) with
804 Ti Stand or 803 Ti Stand (KF)
Connections for stirrers and intelligent dosing 4 MSB connections
elements (Metrohm Serial Bus, Daisy Chain)
Connection for sample changer 1 sample changer via USB
Connections for balances, printer, PC, Via 2 USB Slave Ports, RS-232/USB Box
PC keyboard, barcode reader and/or Lab Link (option)
Temperature sensor Pt 1000 or NTC –
Differential amplifier Option –
Real-time curve display on Touch Control or
Yes
PC screen
DET Dynamic equivalence-point titration Yes –
MET Monotonic equivalence-point titration Yes –
SET Titration to preset endpoints with
Yes –
automatic conditioning
KFT Volumetric Karl Fischer titration with
– Yes
automatic conditioning
MEAS Measuring mode for pH, U/mV, T/°C,
Yes –
Ipol, Upol
CAL Calibration with automatic buffer
Yes –
recognition
Additional titration curve evaluation for: fixed
Yes –
endpoints, pK values (HNP)
Comprehensive GLP/GMP functions; complies
Yes
with FDA 21 CFR Part 11
4
5. Uniquely intelligent –
easy to operate
Call up the method – press start
Standard user methods facilitate familiarization with the system and allow the Titrando to be used
immediately. By using our methods you can profit from our many years of experience in the titra-
tion field. All titration methods developed on Metrohm Titrinos can be converted into Titrando
methods automatically using a PC. As storage media for your methods, sample data and results
there are the Titrando itself, a memory card or the PC with its numerous possibilities.
Intelligence creates transparency
Operating the Titrando System is simple and intuitive. In addition, the following tools make life
easier for the Titrando user:
• The «Quick Access» function (direct parameters) allows direct access to the parameters required
for the given application. This means that it is no longer necessary for you to click your way
through different operating levels!
• The «Help» fixed key shows a content-related help text in the display. The «Follow me» help
function is available when working with a PC. Continuous explanations about the current
surroundings are given in a separate window and further possible procedures are indicated.
• The standard user methods can be modified to suit your requirements. Method templates and
calculation formula templates are available for developing your own methods. Methods can be
stored under meaningful method names (32 characters) and structured directories can be used;
this makes sorting, identification and searching much easier.
• Whereas in the expert dialog all settings are available, the routine dialog can be freely configu-
red, i.e. it can be custom-made to meet the requirements of the particular user. This means that
users can load their «profiles» from the personal Keycard and see only those operating elements
that they actually need.
5
6. Brainy dosing elements with
certification
Metrohm’s Exchange Unit sets new standards with regard to reliability. Each Exchange Unit is
equipped with a data chip. The Titrando automatically reads from it all the data that it needs to
carry out the titration properly, i.e. type of reagent, titer, last titer determination, shelf-life data and
much more. In addition, the Titrando compares the data it has obtained with the selected method
and carries out a plausibility test. If the result is negative then a clear error message appears.
In addition, each Exchange Unit is provided with serial and cylinder numbers and is supplied with
a certificate of its own. The Titrando checks the preset intervals for the titer determination of the
titrant. This ensures that work is always carried out with the exact titer.
6
7. The iTrodes –
electrodes with brains
The electrode used for the titration is really the most important component of any titration system.
The iTrodes represent our new intelligent electrode generation and guarantee complete traceability
of the analytical result to each component participating in the analysis.
Digital identification – no more mix-ups
The built-in memory chip allows the storage of such important sensor data as article and serial
numbers, calibration data, calibration history, working life and calibration validity period. All the
sensor data is read in automatically when the iTrode is connected to the 888 Titrando. Mix-ups
or editing errors are therefore eliminated. The electrode is identified automatically. If the type of
electrode is not the same as that defined in the method then the user is informed. This means
that it is not possible to use an incorrect electrode.
Storage of calibration data – outliers have no chance
Monitoring functions allow the exclusion of electrodes whose calibration data lies outside the
limits or whose calibration period has already expired. If the sensor is used with different instru-
ments or if you wish to prevent inexperienced users from having to calibrate the electrode on their
own instruments then the electrode can be calibrated on a different instrument under defined
conditions. The calibration data stored in the chip makes the electrode transferable; it does not
need to be recalibrated each time that it is used with a different instrument.
Compatible with all existing sensors
Despite its new digital measuring interface and intelligent sensors, the
888 Titrando with combined analog and digital measuring input also
supports conventional sensors. This means that you can continue to
use all your sensors.
7
8. Karl Fischer titration
with the 890 Titrando
The sophisticated control algorithm and the increased volume resolution of
the 890 Titrando’s intelligent Exchange Unit guarantee highly precise results
combined with easy and intuitive user guidance.
The KF icons show you at a glance whether the instrument is still busy condi-
tioning or whether you can start the water determination.
The iodine drop indicates the KF reagent addition during conditioning.
Conditioning is finished and the sample can be added.
The electrode test and the newly created parameter «safety stop» prevent cell
run-over during conditioning. If, for example, the electrode is not connected
correctly or the titration cell is very humid, conditioning is stopped after a given
time or a given volume of KF reagent added. This new feature increases work safety in your labo-
ratory.
The 803 Ti Stand for KF titration
Use the 803 Ti Stand for stirring and manually exchanging the spent titration vessel contents.
With the integrated membrane pump, solvent can be aspirated or added without the cell having
to be opened. This translates into vastly reduced conditioning times.
8
9. The Titrando in the modern
laboratory
Touch Control = user comfort
The Touch Control is a decidedly ergonomic and modern operating element. You can hold it in your
hand, put it on the laboratory bench or use a holder (option) to attach it to a rod or hook it onto the
wall. These last two possibilities save space and also protect the Touch Control from chemicals. Up to
three Titrandos can be controlled by a single Touch Control.
Titrando and PC – a harmonic duo
No matter whether you operate the Titrando with the Touch Control and your fingers or via a PC and
a mouse – both appearance and operation are practically identical. Methods and determinations are
100% compatible. The titration software tiamoTM – titration and more – opens up many other possi-
bilities such as database functionality, parallel titration with several instruments and much more.
Data management is knowledge management
The data that your Titrando system provides you with can be printed out and stored in a conventional
manner. However, all advanced data management functions are available, for example storage on a
PCMCIA card (CompactFlash) that is simply inserted in the Touch Control, in the PCMCIA port of the
PC or an appropriate card reader. If you work with PC Control or tiamoTM, you can use all the storage
options offered by the PC world, and on request the Titrando can produce a machine-readable
PC/LIMS report.
Lab Link
Lab Link opens up internal networks to the Titrando and makes it Internet-compatible, with all that
this implies. In this way, the Titrando can be integrated into LIMS, methods and determinations can
be downloaded from the internal networks or saved on them, printers can be used for printing out
analysis reports. The Titrando is even accessible from the office by remote control.
Compatibility and traceability
The Titrando System is entirely oriented towards quality management in the laboratory and offers the
following possibilities:
• Auto-diagnostic test after switching on.
• Monitoring of validation and service intervals.
• Monitoring of the calibration data of sensors.
• Monitoring of titers and results.
• All changes to the methods are documented.
• Strict control of rights of access using login and password, complying with FDA Regulation 21 CFR
Part 11 regarding «electronic signature» and «electronic record».
9
10. Integrated automation
Increasing sample numbers, time-consuming sample preparation steps and unattended overnight
operation are good reasons for using sample changers. The 888 and 890 Titrandos have the neces-
sary intelligence to control sample changers. Whether you require small or large sample capacity,
one or two working stations, sample metering, sample preparation, liquid handling, rinsing and
calibration of the electrodes – the 814 USB Sample Processor and 815 Robotic USB Sample Processor
XL offer a high degree of automation at low investment costs. It’s amazing: You simply connect
the sample changer to the Titrando’s USB port and the world of automation opens up to you. Our
sample changer brochure supplies detailed information on the automation possibilities.
10
11. Ordering information, options
2.888.0110 888 Titrando with Touch Control
1 x 2.888.0010 888 Titrando
1 x 2.840.0100 840 Touch Control
1 x 2.801.0040 801 Stirrer (magnetic)
1 x 6.3026.220 Intelligent Exchange Unit (20 mL)
1 x 6.0262.100 Ecotrode plus
1 x 6.2104.020 Electrode cable
2.888.0210 888 Titrando with tiamoTM light
1 x 2.888.0010 888 Titrando
1 x 6.6056.131 tiamoTM 1.3 light
1 x 6.2151.000 Cable USB A – Mini DIN 8 pins
1 x 2.801.0040 801 Stirrer (magnetic)
1 x 6.3026.220 Intelligent Exchange Unit (20 mL)
1 x 6.0262.100 Ecotrode plus
1 x 6.2104.020 Electrode cable
2.890.0110 890 Titrando with Touch Control
1 x 2.890.0010 890 Titrando
1 x 2.840.0100 840 Touch Control
1 x 2.803.0010 803 Ti Stand
1 x 6.3026.210 Intelligent Exchange Unit (10 mL)
2.890.0210 890 Titrando with tiamoTM light
1 x 2.890.0010 890 Titrando
1 x 6.6056.131 tiamoTM 1.3 light
1 x 6.2151.000 Cable USB A – Mini DIN 8 pins
1 x 2.803.0010 803 Ti Stand
1 x 6.3026.210 Intelligent Exchange Unit (10 mL)
Optional accessories
2.805.0010 805 Dosimat
6.3026.120 Intelligent Exchange Unit 1 mL for 805 Dosimat
6.3026.150 Intelligent Exchange Unit 5 mL for 805 Dosimat
6.3026.210 Intelligent Exchange Unit 10 mL for 805 Dosimat
6.3026.220 Intelligent Exchange Unit 20 mL for 805 Dosimat
6.3026.250 Intelligent Exchange Unit 50 mL for 805 Dosimat
2.800.0010 800 Dosino
6.3032.120 Intelligent Dosing Unit 2 mL for 800 Dosino
6.3032.150 Intelligent Dosing Unit 5 mL for 800 Dosino
6.3032.210 Intelligent Dosing Unit 10 mL for 800 Dosino
6.3032.220 Intelligent Dosing Unit 20 mL for 800 Dosino
6.3032.250 Intelligent Dosing Unit 50 mL for 800 Dosino
2.804.0040 804 Ti Stand with support
2.802.0040 802 Stirrer (rod) for 804
2.847.0010 USB Lab Link
6.2148.020 RS-232/USB Box
11
12. Metrohm AG
CH-9101 Herisau/Switzerland
Phone +41 71 353 85 85
Fax +41 71 353 89 01
www.metrohm.com
info@metrohm.com
www.titrando.com
Layout by Ecknauer+Schoch ASW, printed in Switzerland by Metrohm AG., Herisau
8.888.5001EN – 2008-09
Subject to change