This document discusses strengthening routine health information systems in Africa through regional collaboration. It reviews where sub-Saharan Africa is currently in terms of health information system development and global trends. It explores existing networks like the African Centre for eHealth Excellence and the HISP network that can be leveraged. Finally, it proposes next steps like consolidating the efforts of these networks to implement a 5-point call to action and developing a monitoring and evaluation framework for peer review across countries.