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Microscopic Anatomy of Heart Muscle
Cardiac Muscle Contraction
 Heart muscle:
 Is stimulated by nerves and is self-excitable
(automaticity)
 Contracts as a unit
 Has a long (250 ms) absolute refractory period
 Cardiac muscle contraction is similar to skeletal
muscle contraction
Heart Physiology: Intrinsic Conduction System
 Autorhythmic cells:
 Initiate action potentials
 Have unstable resting potentials called pacemaker
potentials
Heart Physiology: Sequence of Excitation
Heart Physiology: Sequence of Excitation
 Sinoatrial (SA) node generates impulses about 75
times/minute
 Atrioventricular (AV) node delays the impulse
approximately 0.1 second
 Impulse passes from atria to ventricles via the
atrioventricular bundle (bundle of His)
Heart Physiology: Sequence of Excitation
 AV bundle splits into two pathways in the
interventricular septum (bundle branches)
 Bundle branches carry the impulse toward the apex
of the heart
 Purkinje fibers carry the impulse to the heart apex
and ventricular walls
Heart Excitation

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5063905.ppt

  • 1. Microscopic Anatomy of Heart Muscle
  • 2. Cardiac Muscle Contraction  Heart muscle:  Is stimulated by nerves and is self-excitable (automaticity)  Contracts as a unit  Has a long (250 ms) absolute refractory period  Cardiac muscle contraction is similar to skeletal muscle contraction
  • 3. Heart Physiology: Intrinsic Conduction System  Autorhythmic cells:  Initiate action potentials  Have unstable resting potentials called pacemaker potentials
  • 5. Heart Physiology: Sequence of Excitation  Sinoatrial (SA) node generates impulses about 75 times/minute  Atrioventricular (AV) node delays the impulse approximately 0.1 second  Impulse passes from atria to ventricles via the atrioventricular bundle (bundle of His)
  • 6. Heart Physiology: Sequence of Excitation  AV bundle splits into two pathways in the interventricular septum (bundle branches)  Bundle branches carry the impulse toward the apex of the heart  Purkinje fibers carry the impulse to the heart apex and ventricular walls