The document provides information on the evaluation and management of osteoarthritis (OA). It presents two case studies: a 65-year-old man with knee pain likely due to past knee injury, and a 75-year-old woman with OA in both knees, hips, and thumbs likely due to family history and genetics. The document discusses risk factors for OA, symptoms, diagnostic studies, pharmacological and non-pharmacological treatment options including exercise, topical agents, braces, and surgery.