This case study describes the care of a patient who came into the hospital with sepsis and progressed to acute respiratory and renal failure requiring mechanical ventilation and a tracheostomy. The patient did not respond to any external stimuli except pain. Through researching the patient's conditions and monitoring lab values, the student was able to understand the pathophysiology and appropriately treat the patient's multiple organ dysfunction syndrome. The experience provided an opportunity for the student to learn how to communicate with and provide comfort to patients with limited response abilities.