This study compared rates of tuberculosis infections in Diyala province, Iraq between 2010 and 2015. The number of TB cases increased from 147 infections in 2010 to 405 infections in 2015. While the percentage of infected patients decreased from 10.3% of total patients in 2010 to 7% in 2015. Most infections were in males and in urban areas with no significant differences between years. The highest rates of infection shifted to older age groups from 2010 to 2015.