This document contains a quiz on microbial diseases of the nervous system. It is divided into sections on the nervous system, bacterial diseases, fungal and protozoan diseases, viral diseases, and prion diseases. Each section contains multiple choice questions on topics related to specific pathogens that can infect the nervous system, their symptoms, modes of transmission, and sterilization methods. The questions range in value from $100 to $500 and provide the answers when selected.

1. Bradley W. Christian, McLennan Community College
© 2016 Pearson Education, Inc.
$200
$100
$300
$400
$500
$100
$200
$300
$400
$500
$100
$200
$300
$400
$500
$100
$200
$300
$400
$500
$100
$200
$300
$400
$500
Chapter 22: Microbial Diseases of the Nervous System
The Nervous
System
Bacterial
Diseases
Fungal and
Protozoan
Diseases
Viral
Diseases
Prion
Diseases
FINAL ROUND

2. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$100 Question
In the brain, cerebrospinal fluid flows through the
a. dura mater.
b. subarachnoid space.
c. arachnoid mater.
d. pia mater.
ANSWER
BACK TO GAME

3. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$100 Answer
In the brain, cerebrospinal fluid flows through the
a. dura mater.
b. subarachnoid space.
c. arachnoid mater.
d. pia mater.
BACK TO GAME

4. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$200 Question
What is the order of the layer of meninges from
the innermost to the outermost?
a. arachnoid mater, dura mater, pia mater
b. dura mater, arachnoid mater, pia mater
c. pia mater, dura mater, arachnoid mater
d. pia mater, arachnoid mater, dura mater
ANSWER
BACK TO GAME

5. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$200 Answer
What is the order of the layer of meninges from
the innermost to the outermost?
a. arachnoid mater, dura mater, pia mater
b. dura mater, arachnoid mater, pia mater
c. pia mater, dura mater, arachnoid mater
d. pia mater, arachnoid mater, dura mater
BACK TO GAME

6. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$300 Question
Inflammation of the brain is called
a. meningitis.
b. encephalitis.
c. neuritis.
d. hydrocephalus.
ANSWER
BACK TO GAME

7. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$300 Answer
Inflammation of the brain is called
a. meningitis.
b. encephalitis.
c. neuritis.
d. hydrocephalus.
BACK TO GAME

8. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$400 Question
Drugs can cross the blood–brain barrier ONLY if
they are
a. large-molecular-weight molecules.
b. small-molecular-weight molecules.
c. water-soluble.
d. lipid-soluble.
ANSWER
BACK TO GAME

9. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$400 Answer
Drugs can cross the blood–brain barrier ONLY if
they are
a. large-molecular-weight molecules.
b. small-molecular-weight molecules.
c. water-soluble.
d. lipid-soluble.
BACK TO GAME

10. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$500 Question
Bacteria can grow well in cerebrospinal fluid
because it has low levels of circulating
antibodies and
a. water.
b. glucose.
c. complement.
d. sodium.
ANSWER
BACK TO GAME

11. © 2016 Pearson Education, Inc.
Topic 1: The Nervous System
$500 Answer
Bacteria can grow well in cerebrospinal fluid
because it has low levels of circulating
antibodies and
a. water.
b. glucose.
c. complement.
d. sodium.
BACK TO GAME

12. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$100 Question
Which type of meningitis is also a frequent cause
of pneumonia?
a. meningococcal meningitis
b. pneumococcal meningitis
c. listeriosis
d. Haemophilus influenzae meningitis
ANSWER
BACK TO GAME

13. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$100 Answer
Which type of meningitis is also a frequent cause
of pneumonia?
a. meningococcal meningitis
b. pneumococcal meningitis
c. listeriosis
d. Haemophilus influenzae meningitis
BACK TO GAME

14. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$200 Question
The symptoms of tetanus are caused by a(n)
a. neurotoxin.
b. leukocidin.
c. hemolysin.
d. endotoxin.
ANSWER
BACK TO GAME

15. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$200 Answer
The symptoms of tetanus are caused by a(n)
a. neurotoxin.
b. leukocidin.
c. hemolysin.
d. endotoxin.
BACK TO GAME

16. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$300 Question
Which bacterium is known to cause stillbirth and
neurological disease in animals?
a. Listeria monocytogenes
b. Streptococcus pneumoniae
c. Clostridium botulinum
d. Haemophilus influenzae
ANSWER
BACK TO GAME

17. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$300 Answer
Which bacterium is known to cause stillbirth and
neurological disease in animals?
a. Listeria monocytogenes
b. Streptococcus pneumoniae
c. Clostridium botulinum
d. Haemophilus influenzae
BACK TO GAME

18. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$400 Question
Which of the following would be a symptom of
botulism?
a. disfiguring nodules on the skin
b. lockjaw
c. flaccid paralysis
d. sepsis
ANSWER
BACK TO GAME

19. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$400 Answer
Which of the following would be a symptom of
botulism?
a. disfiguring nodules on the skin
b. lockjaw
c. flaccid paralysis
d. sepsis
BACK TO GAME

20. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$500 Question
Which of the following statements about
Mycobacterium leprae is FALSE?
a. It has an optimum growth temperature of
37°C.
b. It has a generation time of 12 days.
c. It has never been grown on artificial media.
d. It grows in the peripheral nervous system.
ANSWER
BACK TO GAME

21. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Diseases
$500 Answer
Which of the following statements about
Mycobacterium leprae is FALSE?
a. It has an optimum growth temperature of
37°C.
b. It has a generation time of 12 days.
c. It has never been grown on artificial media.
d. It grows in the peripheral nervous system.
BACK TO GAME

22. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$100 Question
Trypanosoma brucei is transmitted by
a. tsetse flies.
b. body lice.
c. houseflies.
d. head lice.
ANSWER
BACK TO GAME

23. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$100 Answer
Trypanosoma brucei is transmitted by
a. tsetse flies.
b. body lice.
c. houseflies.
d. head lice.
BACK TO GAME

24. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$200 Question
Which organism is highly fatal in
immunocompromised patients and is transmitted
by the inhalation of dried bird droppings?
a. Trypanosoma brucei
b. Naegleria fowleri
c. Listeria monocytogenes
d. Cryptococcus neoformans
ANSWER
BACK TO GAME

25. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$200 Answer
Which organism is highly fatal in
immunocompromised patients and is transmitted
by the inhalation of dried bird droppings?
a. Trypanosoma brucei
b. Naegleria fowleri
c. Listeria monocytogenes
d. Cryptococcus neoformans
BACK TO GAME

26. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$300 Question
Trypanosomiasis is also known as
a. amebic meningoencephalitis.
b. mad cow disease.
c. sleeping sickness.
d. lockjaw.
ANSWER
BACK TO GAME

27. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$300 Answer
Trypanosomiasis is also known as
a. amebic meningoencephalitis.
b. mad cow disease.
c. sleeping sickness.
d. lockjaw.
BACK TO GAME

28. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$400 Question
Which organism is widespread in freshwater and
feeds on brain tissue?
a. Cryptococcus neoformans
b. Acanthamoeba
c. Naegleria fowleri
d. Trypanosoma brucei
ANSWER
BACK TO GAME

29. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$400 Answer
Which organism is widespread in freshwater and
feeds on brain tissue?
a. Cryptococcus neoformans
b. Acanthamoeba
c. Naegleria fowleri
d. Trypanosoma brucei
BACK TO GAME

30. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$500 Question
Granulomatous amebic encephalitis is caused by
a. Acanthamoeba.
b. Naegleria fowleri.
c. Trypansoma brucei.
d. Cryptococcus neoformans.
ANSWER
BACK TO GAME

31. © 2016 Pearson Education, Inc.
Topic 3: Fungal and Protozoan Diseases
$500 Answer
Granulomatous amebic encephalitis is caused by
a. Acanthamoeba.
b. Naegleria fowleri.
c. Trypansoma brucei.
d. Cryptococcus neoformans.
BACK TO GAME

32. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$100 Question
Which of the following diseases is caused by a
prion?
a. rabies
b. Creutzfeldt-Jakob disease
c. polio
d. wound botulism
ANSWER
BACK TO GAME

33. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$100 Answer
Which of the following diseases is caused by a
prion?
a. rabies
b. Creutzfeldt-Jakob disease
c. polio
d. wound botulism
BACK TO GAME

34. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$200 Question
A prion is a(n)
a. abnormally folded protein.
b. protein subunit.
c. form of a bacterium.
d. viral particle.
ANSWER
BACK TO GAME

35. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$200 Answer
A prion is a(n)
a. abnormally folded protein.
b. protein subunit.
c. form of a bacterium.
d. viral particle.
BACK TO GAME

36. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$300 Question
The prion disease associated with cannibalism is
a. sheep scrapie.
b. kuru.
c. mad cow disease.
d. chronic wasting disease.
ANSWER
BACK TO GAME

37. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$300 Answer
The prion disease associated with cannibalism is
a. sheep scrapie.
b. kuru.
c. mad cow disease.
d. chronic wasting disease.
BACK TO GAME

38. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$400 Question
One hypothesis on the origin of mad cow disease
in cattle concerns
a. cattle feed contaminated with scrapie.
b. direct contact with animals infected with
scrapie.
c. direct contact with other infected species.
d. hormones in cattle feed.
ANSWER
BACK TO GAME

39. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$400 Answer
One hypothesis on the origin of mad cow disease
in cattle concerns
a. cattle feed contaminated with scrapie.
b. direct contact with animals infected with
scrapie.
c. direct contact with other infected species.
d. hormones in cattle feed.
BACK TO GAME

40. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$500 Question
To sterilize instruments contaminated with prions,
you should use
a. dry heat.
b. routine autoclaving.
c. UV light.
d. a strong solution of sodium hydroxide.
ANSWER
BACK TO GAME

41. © 2016 Pearson Education, Inc.
Topic 4: Prion Diseases
$500 Answer
To sterilize instruments contaminated with prions,
you should use
a. dry heat.
b. routine autoclaving.
c. UV light.
d. a strong solution of sodium hydroxide.
BACK TO GAME

42. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$100 Question
Which disease has an incubation period that is
usually long enough to allow immunity to
develop from postexposure vaccination?
a. polio
b. rabies
c. West Nile virus
d. Japanese encephalitis
ANSWER
BACK TO GAME

43. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$100 Answer
Which disease has an incubation period that is
usually long enough to allow immunity to
develop from postexposure vaccination?
a. polio
b. rabies
c. West Nile virus
d. Japanese encephalitis
BACK TO GAME

44. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$200 Question
Which disease is transmitted via ingestion of
contaminated water and can cause paralysis?
a. rabies
b. Japanese encephalitis
c. West Nile encephalitis
d. polio
ANSWER
BACK TO GAME

45. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$200 Answer
Which disease is transmitted via ingestion of
contaminated water and can cause paralysis?
a. rabies
b. Japanese encephalitis
c. West Nile encephalitis
d. polio
BACK TO GAME

46. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$300 Question
What disease is closely related to and clinically
indistinguishable from rabies?
a. eastern equine encephalitis
b. West Nile virus
c. polio
d. European bat lyssavirus
ANSWER
BACK TO GAME

47. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$300 Answer
What disease is closely related to and clinically
indistinguishable from rabies?
a. eastern equine encephalitis
b. West Nile virus
c. polio
d. European bat lyssavirus
BACK TO GAME

48. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$400 Question
Which type of arboviral encephalitis was
introduced to the United States in 1999 and is
maintained in a bird-mosquito-bird cycle?
a. eastern equine encephalitis
b. Japanese encephalitis
c. West Nile virus
d. California encephalitis
ANSWER
BACK TO GAME

49. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$400 Answer
Which type of arboviral encephalitis was
introduced to the United States in 1999 and is
maintained in a bird-mosquito-bird cycle?
a. eastern equine encephalitis
b. Japanese encephalitis
c. West Nile virus
d. California encephalitis
BACK TO GAME

50. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$500 Question
In the United States, the MOST common cause of
rabies in humans is from
a. raccoons.
b. silver-haired bats.
c. dogs.
d. honey badgers.
ANSWER
BACK TO GAME

51. © 2016 Pearson Education, Inc.
Topic 5: Viral Diseases
$500 Answer
In the United States, the MOST common cause of
rabies in humans is from
a. raccoons.
b. silver-haired bats.
c. dogs.
d. honey badgers.
BACK TO GAME

52. © 2016 Pearson Education, Inc.
FINAL ROUND Question
The Sabin polio vaccine is a(n)
a. conjugated vaccine.
b. attenuated vaccine.
c. toxoid vaccine.
d. inactivated vaccine.
ANSWER
BACK TO GAME

53. © 2016 Pearson Education, Inc.
FINAL ROUND Answer
The Sabin polio vaccine is a(n)
a. conjugated vaccine.
b. attenuated vaccine.
c. toxoid vaccine.
d. inactivated vaccine.
BACK TO GAME