This document contains a quiz on microbial pathogenesis covering topics of portals of entry, bacterial pathogens, viral pathogens, and eukaryotic pathogens. It consists of multiple choice questions with answers on these topics, worth $100 to $500 per question. The quiz is designed to test knowledge of microbial disease mechanisms like toxins, biofilms, antigenic variation, and more.

1. Bradley W. Christian, McLennan Community College
© 2016 Pearson Education, Inc.
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Chapter 15: Microbial Mechanisms of Pathogenicity
Portals of
Entry
Bacterial
Pathogens
Viral
Pathogens
Portals of
Exit
Eukaryotic
Pathogens
FINAL ROUND

2. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$100 Question
The easiest and MOST frequently traveled portal
of entry for infectious microorganisms is the
a. parenteral route.
b. respiratory tract.
c. gastrointestinal tract.
d. skin.
ANSWER
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3. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$100 Answer
The easiest and MOST frequently traveled portal
of entry for infectious microorganisms is the
a. parenteral route.
b. respiratory tract.
c. gastrointestinal tract.
d. skin.
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4. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$200 Question
The degree of pathogenicity of an organism is
known as the
a. antigenicity.
b. toxigenicity.
c. virulence.
d. cytopathic effect.
ANSWER
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5. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$200 Answer
The degree of pathogenicity of an organism is
known as the
a. antigenicity.
b. toxigenicity.
c. virulence.
d. cytopathic effect.
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6. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$300 Question
Which of the following is NOT an example of the
parenteral route of entry?
a. conjunctiva
b. surgery
c. injection
d. bite
ANSWER
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7. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$300 Answer
Which of the following is NOT an example of the
parenteral route of entry?
a. conjunctiva
b. surgery
c. injection
d. bite
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8. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$400 Question
What is the preferred portal of entry for
chlamydia?
a. genitourinary tract
b. gastrointestinal tract
c. skin
d. respiratory tract
ANSWER
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9. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$400 Answer
What is the preferred portal of entry for
chlamydia?
a. genitourinary tract
b. gastrointestinal tract
c. skin
d. respiratory tract
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10. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$500 Question
Communities of microbes that cling to surfaces
and share available nutrients are called
a. biofilms.
b. fimbriae.
c. ligands.
d. superantigens.
ANSWER
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11. © 2016 Pearson Education, Inc.
Topic 1: Portals of Entry
$500 Answer
Communities of microbes that cling to surfaces
and share available nutrients are called
a. biofilms.
b. fimbriae.
c. ligands.
d. superantigens.
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12. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$100 Question
The outer portion of gram-negative cell walls
contain
a. exotoxins.
b. endotoxins.
c. siderophores.
d. exoenzymes.
ANSWER
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13. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$100 Answer
The outer portion of gram-negative cell walls
contain
a. exotoxins.
b. endotoxins.
c. siderophores.
d. exoenzymes.
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14. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$200 Question
What is the action of bacterial kinases?
a. to coagulate fibrinogen
b. to hydrolyze hyaluronic acid
c. to break down fibrin
d. to break down collagen
ANSWER
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15. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$200 Answer
What is the action of bacterial kinases?
a. to coagulate fibrinogen
b. to hydrolyze hyaluronic acid
c. to break down fibrin
d. to break down collagen
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16. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$300 Question
Exotoxins that attack liver cells are known as
a. leukotoxins.
b. cytotoxins.
c. hepatotoxins.
d. enterotoxins.
ANSWER
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17. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$300 Answer
Exotoxins that attack liver cells are known as
a. leukotoxins.
b. cytotoxins.
c. hepatotoxins.
d. enterotoxins.
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18. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$400 Question
Proteins secreted by pathogens that bind iron are
known as
a. superantigens.
b. siderophores.
c. leukocidins.
d. hemolysins.
ANSWER
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19. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$400 Answer
Proteins secreted by pathogens that bind iron are
known as
a. superantigens.
b. siderophores.
c. leukocidins.
d. hemolysins.
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20. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$500 Question
Toxins produced by some gram-negative bacteria
that damage DNA are called
a. streptolysins.
b. genotoxins.
c. A-B toxins.
d. membrane-disrupting toxins.
ANSWER
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21. © 2016 Pearson Education, Inc.
Topic 2: Bacterial Pathogens
$500 Answer
Toxins produced by some gram-negative bacteria
that damage DNA are called
a. streptolysins.
b. genotoxins.
c. A-B toxins.
d. membrane-disrupting toxins.
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22. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$100 Question
Which virus irreversibly stops mitosis?
a. human immunodeficiency virus (HIV)
b. herpes simplex virus
c. rabies virus
d. measles virus
ANSWER
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23. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$100 Answer
Which virus irreversibly stops mitosis?
a. human immunodeficiency virus (HIV)
b. herpes simplex virus
c. rabies virus
d. measles virus
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24. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$200 Question
Substances produced by virus-infected cells that
protect neighboring uninfected cells from infection
are called
a. interferons.
b. inclusion bodies.
c. immunoglobulins.
d. leukocidins.
ANSWER
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25. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$200 Answer
Substances produced by virus-infected cells that
protect neighboring uninfected cells from infection
are called
a. interferons.
b. inclusion bodies.
c. immunoglobulins.
d. leukocidins.
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26. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$300 Question
Which of the following refers to the visible effects
of a viral infection?
a. lysogenic conversion
b. lysogenic effects
c. cytopathic effects
d. cytopathic conversion
ANSWER
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27. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$300 Answer
Which of the following refers to the visible effects
of a viral infection?
a. lysogenic conversion
b. lysogenic effects
c. cytopathic effects
d. cytopathic conversion
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28. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$400 Question
What are the granules found in the cytoplasm or
nucleus of some virus-infected cells?
a. syncytia
b. endotoxins
c. lysosomes
d. inclusion bodies
ANSWER
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29. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$400 Answer
What are the granules found in the cytoplasm or
nucleus of some virus-infected cells?
a. syncytia
b. endotoxins
c. lysosomes
d. inclusion bodies
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30. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$500 Question
Viruses that transform cells by causing loss of
contact inhibition result in
a. the formation of a syncytium.
b. chromosomal breakage.
c. unregulated cell growth.
d. antigenic changes on the host cell.
ANSWER
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31. © 2016 Pearson Education, Inc.
Topic 3: Viral Pathogens
$500 Answer
Viruses that transform cells by causing loss of
contact inhibition result in
a. the formation of a syncytium.
b. chromosomal breakage.
c. unregulated cell growth.
d. antigenic changes on the host cell.
BACK TO GAME

32. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$100 Question
Which of the following is NOT a way fungi cause
disease?
a. by using antigenic variation
b. by producing toxins
c. by secreting protease
d. by provoking an allergic response
ANSWER
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33. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$100 Answer
Which of the following is NOT a way fungi cause
disease?
a. by using antigenic variation
b. by producing toxins
c. by secreting protease
d. by provoking an allergic response
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34. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$200 Question
What type of organism produces saxitoxin?
a. helminth
b. alga
c. fungus
d. plant
ANSWER
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35. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$200 Answer
What type of organism produces saxitoxin?
a. helminth
b. alga
c. fungus
d. plant
BACK TO GAME

36. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$300 Question
Which of the following toxins is an alkaloid that
can cause hallucinations resembling those
produced by LSD?
a. aflatoxin
b. ergot alkaloid
c. phalloidin
d. amanitin
ANSWER
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37. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$300 Answer
Which of the following toxins is an alkaloid that
can cause hallucinations resembling those
produced by LSD?
a. aflatoxin
b. ergot alkaloid
c. phalloidin
d. amanitin
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38. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$400 Question
Which of the following protozoa use antigenic
variation to stay one step ahead of the host's
immune system?
a. Toxoplasma
b. Cryptosporidium
c. Trypanosoma
d. Plasmodium
ANSWER
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39. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$400 Answer
Which of the following protozoa use antigenic
variation to stay one step ahead of the host's
immune system?
a. Toxoplasma
b. Cryptosporidium
c. Trypanosoma
d. Plasmodium
BACK TO GAME

40. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$500 Question
What is the causative agent of elephantiasis?
a. Entamoeba histolytica
b. Candida albicans
c. Cryptococcus neoformans
d. Wuchereria bancrofti
ANSWER
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41. © 2016 Pearson Education, Inc.
Topic 4: Eukaryotic Pathogens
$500 Answer
What is the causative agent of elephantiasis?
a. Entamoeba histolytica
b. Candida albicans
c. Cryptococcus neoformans
d. Wuchereria bancrofti
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42. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$100 Question
Arthropods provide a portal of exit for microbes
via the
a. skin.
b. blood.
c. respiratory tract.
d. genitourinary tract.
ANSWER
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43. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$100 Answer
Arthropods provide a portal of exit for microbes
via the
a. skin.
b. blood.
c. respiratory tract.
d. genitourinary tract.
BACK TO GAME

44. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$200 Question
Sneezing is a portal of exit for the
a. gastrointestinal tract.
b. respiratory tract.
c. blood.
d. genitourinary tract.
ANSWER
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45. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$200 Answer
Sneezing is a portal of exit for the
a. gastrointestinal tract.
b. respiratory tract.
c. blood.
d. genitourinary tract.
BACK TO GAME

46. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$300 Question
Pathogens that are discharged from the
respiratory tract can cause which of the following
diseases?
a. salmonella
b. whooping cough
c. poliomyelitis
d. tetanus
ANSWER
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47. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$300 Answer
Pathogens that are discharged from the
respiratory tract can cause which of the following
diseases?
a. salmonella
b. whooping cough
c. poliomyelitis
d. tetanus
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48. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$400 Question
Infections transmitted from the skin include
a. warts.
b. tularemia.
c. yellow fever.
d. plague.
ANSWER
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49. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$400 Answer
Infections transmitted from the skin include
a. warts.
b. tularemia.
c. yellow fever.
d. plague.
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50. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$500 Question
Which of the following diseases can be
transmitted by a biting insect?
a. shigellosis
b. mumps
c. tularemia
d. chickenpox
ANSWER
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51. © 2016 Pearson Education, Inc.
Topic 5: Portals of Exit
$500 Answer
Which of the following diseases can be
transmitted by a biting insect?
a. shigellosis
b. mumps
c. tularemia
d. chickenpox
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52. © 2016 Pearson Education, Inc.
FINAL ROUND Question
Septic shock can result from using antibiotics to
treat
a. gram-negative bacterial infections.
b. fungal infections.
c. viral infections.
d. protozoan infections.
ANSWER
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53. © 2016 Pearson Education, Inc.
FINAL ROUND Answer
Septic shock can result from using antibiotics to
treat
a. gram-negative bacterial infections.
b. fungal infections.
c. viral infections.
d. protozoan infections.
BACK TO GAME