This document provides information about biosensors. It defines a biosensor as a device that combines a biological component with a physicochemical detector. The biological component could include enzymes, antibodies, organelles, hormones or nucleic acids. The sensor component analyzes biological signals and converts them into an electrical signal. Some key applications of biosensors mentioned include food analysis, medical diagnosis, environmental monitoring and industrial process control. The document also discusses important milestones in biosensor development and characteristics such as sensitivity, selectivity, response time and linearity that are important for biosensors.
Biotechnology is challenging subject to teach and understand also..its a very interesting subject in pharmacy..all the power point is made as per your syllabus with point to point discussion.
thank you
Biosensers are the integrated receptor transducer device, which is capable of providing selective quantitative or semi-quantitative analytic information using a biological recognition element.
Analytical device.
Contains Biological or Biological derived recognition element to detect specific bio-analyte a transducer to convert a biological signal into an electrical signal.
A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector.The sensitive biological element, e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc., is a biologically derived material or biomimetic component that interacts with, binds with, or recognizes the analyte under study. The biologically sensitive elements can also be created by biological engineering. The transducer or the detector element, which transforms one signal into another one, works in a physicochemical way: optical, piezoelectric, electrochemical, electrochemiluminescence etc., resulting from the interaction of the analyte with the biological element, to easily measure and quantify. The biosensor reader device connects with the associated electronics or signal processors that are primarily responsible for the display of the results in a user-friendly way.[5] This sometimes accounts for the most expensive part of the sensor device, however it is possible to generate a user friendly display that includes transducer and sensitive element (holographic sensor). The readers are usually custom-designed and manufactured to suit the different working principles of biosensors.
BIOSENSOR, PHARMACEUTICAL BIOTECHNOLOGY, B PHARAM, 6TH SEM
Basic components of Biosensor
Working of Biosensor
Types of Biosensor
Electrochemical biosensor
Optical biosensor
Thermal biosensor
Resonant biosensor
Ion-sensitive biosensor
Applications of Biosensor
Nano sensors
sensing device
Father of the Biosensor
components of BIOSENSOR
BASIC PRINCIPLE OF BIOSENSOR
BIO-ELEMENT
TRANSDUCER
DETECTOR
RESPONSE FROM BIO-ELEMENT
IDEAL BIOSENSOR
BASIC CHARACTERESTICS
A biosensor is an analytical device containing an immobilized biological material (enzyme, antibody, nucleic acid, hormone, organelle or whole cell) which can specifically interact with an analyte and produce physical, chemical or electrical signals that can be measured. An analyte is a compound (e.g. glucose, urea, drug, pesticide) whose concentration has to be measured.
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research.
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research.
Biosensor .now what is biosensor .mechanism of biosensor .equipment used in biosensor .All the information contain about biosensor present in this presentation .its really informative .
We have compiled the most important slides from each speaker's presentation. This year’s compilation, available for free, captures the key insights and contributions shared during the DfMAy 2024 conference.
Biotechnology is challenging subject to teach and understand also..its a very interesting subject in pharmacy..all the power point is made as per your syllabus with point to point discussion.
thank you
Biosensers are the integrated receptor transducer device, which is capable of providing selective quantitative or semi-quantitative analytic information using a biological recognition element.
Analytical device.
Contains Biological or Biological derived recognition element to detect specific bio-analyte a transducer to convert a biological signal into an electrical signal.
A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector.The sensitive biological element, e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc., is a biologically derived material or biomimetic component that interacts with, binds with, or recognizes the analyte under study. The biologically sensitive elements can also be created by biological engineering. The transducer or the detector element, which transforms one signal into another one, works in a physicochemical way: optical, piezoelectric, electrochemical, electrochemiluminescence etc., resulting from the interaction of the analyte with the biological element, to easily measure and quantify. The biosensor reader device connects with the associated electronics or signal processors that are primarily responsible for the display of the results in a user-friendly way.[5] This sometimes accounts for the most expensive part of the sensor device, however it is possible to generate a user friendly display that includes transducer and sensitive element (holographic sensor). The readers are usually custom-designed and manufactured to suit the different working principles of biosensors.
BIOSENSOR, PHARMACEUTICAL BIOTECHNOLOGY, B PHARAM, 6TH SEM
Basic components of Biosensor
Working of Biosensor
Types of Biosensor
Electrochemical biosensor
Optical biosensor
Thermal biosensor
Resonant biosensor
Ion-sensitive biosensor
Applications of Biosensor
Nano sensors
sensing device
Father of the Biosensor
components of BIOSENSOR
BASIC PRINCIPLE OF BIOSENSOR
BIO-ELEMENT
TRANSDUCER
DETECTOR
RESPONSE FROM BIO-ELEMENT
IDEAL BIOSENSOR
BASIC CHARACTERESTICS
A biosensor is an analytical device containing an immobilized biological material (enzyme, antibody, nucleic acid, hormone, organelle or whole cell) which can specifically interact with an analyte and produce physical, chemical or electrical signals that can be measured. An analyte is a compound (e.g. glucose, urea, drug, pesticide) whose concentration has to be measured.
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research.
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research
Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research.
The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics.
Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research.
Biosensor .now what is biosensor .mechanism of biosensor .equipment used in biosensor .All the information contain about biosensor present in this presentation .its really informative .
We have compiled the most important slides from each speaker's presentation. This year’s compilation, available for free, captures the key insights and contributions shared during the DfMAy 2024 conference.
A review on techniques and modelling methodologies used for checking electrom...nooriasukmaningtyas
The proper function of the integrated circuit (IC) in an inhibiting electromagnetic environment has always been a serious concern throughout the decades of revolution in the world of electronics, from disjunct devices to today’s integrated circuit technology, where billions of transistors are combined on a single chip. The automotive industry and smart vehicles in particular, are confronting design issues such as being prone to electromagnetic interference (EMI). Electronic control devices calculate incorrect outputs because of EMI and sensors give misleading values which can prove fatal in case of automotives. In this paper, the authors have non exhaustively tried to review research work concerned with the investigation of EMI in ICs and prediction of this EMI using various modelling methodologies and measurement setups.
6th International Conference on Machine Learning & Applications (CMLA 2024)ClaraZara1
6th International Conference on Machine Learning & Applications (CMLA 2024) will provide an excellent international forum for sharing knowledge and results in theory, methodology and applications of on Machine Learning & Applications.
Hierarchical Digital Twin of a Naval Power SystemKerry Sado
A hierarchical digital twin of a Naval DC power system has been developed and experimentally verified. Similar to other state-of-the-art digital twins, this technology creates a digital replica of the physical system executed in real-time or faster, which can modify hardware controls. However, its advantage stems from distributing computational efforts by utilizing a hierarchical structure composed of lower-level digital twin blocks and a higher-level system digital twin. Each digital twin block is associated with a physical subsystem of the hardware and communicates with a singular system digital twin, which creates a system-level response. By extracting information from each level of the hierarchy, power system controls of the hardware were reconfigured autonomously. This hierarchical digital twin development offers several advantages over other digital twins, particularly in the field of naval power systems. The hierarchical structure allows for greater computational efficiency and scalability while the ability to autonomously reconfigure hardware controls offers increased flexibility and responsiveness. The hierarchical decomposition and models utilized were well aligned with the physical twin, as indicated by the maximum deviations between the developed digital twin hierarchy and the hardware.
Low power architecture of logic gates using adiabatic techniquesnooriasukmaningtyas
The growing significance of portable systems to limit power consumption in ultra-large-scale-integration chips of very high density, has recently led to rapid and inventive progresses in low-power design. The most effective technique is adiabatic logic circuit design in energy-efficient hardware. This paper presents two adiabatic approaches for the design of low power circuits, modified positive feedback adiabatic logic (modified PFAL) and the other is direct current diode based positive feedback adiabatic logic (DC-DB PFAL). Logic gates are the preliminary components in any digital circuit design. By improving the performance of basic gates, one can improvise the whole system performance. In this paper proposed circuit design of the low power architecture of OR/NOR, AND/NAND, and XOR/XNOR gates are presented using the said approaches and their results are analyzed for powerdissipation, delay, power-delay-product and rise time and compared with the other adiabatic techniques along with the conventional complementary metal oxide semiconductor (CMOS) designs reported in the literature. It has been found that the designs with DC-DB PFAL technique outperform with the percentage improvement of 65% for NOR gate and 7% for NAND gate and 34% for XNOR gate over the modified PFAL techniques at 10 MHz respectively.
Understanding Inductive Bias in Machine LearningSUTEJAS
This presentation explores the concept of inductive bias in machine learning. It explains how algorithms come with built-in assumptions and preferences that guide the learning process. You'll learn about the different types of inductive bias and how they can impact the performance and generalizability of machine learning models.
The presentation also covers the positive and negative aspects of inductive bias, along with strategies for mitigating potential drawbacks. We'll explore examples of how bias manifests in algorithms like neural networks and decision trees.
By understanding inductive bias, you can gain valuable insights into how machine learning models work and make informed decisions when building and deploying them.
1. DISCOVER . LEARN . EMPOWER
Biosensors
UNIVERSITY INSTITUTE OF
ENGG.
BE ACAD.UNIT 2
Bachelor of Engineering (Computer Science
& Engineering)
Biology for Engineers SZT-172
2. 2
BIOSENSORS
CO Number Title Level
CO1 To develop the firm foundation in science principles and higher level of
understanding in each of the biology sub-discipline.
Remember
CO2 To excel in career as researcher in both traditional and emerging fields of
science .
Understand
CO3 Understand ethical principles and responsibilities for science practices in
society.
Understand
CO4 To learn the new areas of biology for contemporary research with
interdisciplinary approach
Understand
Course Outcome
3. “Biosensor” : combination of two
parts
•(i) a bio-element
•(ii) a sensor-element
Sensor : carbon electrode, oxygen
electrode, ion sensitive electrode or
photocell.
the “sensor”element :analyses of
biological signals and convert it into
an electrical signal.
“Bio” element : enzyme, antibody,
organelle, hormones, nucleic acids or
whole cells.
www.cuchd.in
WHAT ARE BIOSENSORS?
4. Analytical device, used for the
detection of an analyte, that
combines a biological component
with a physicochemical detector and
are capable of providing either
qualitative or quantitative results. Incorporation of a biomolecule in order to
detect something.
www.cuchd.in
DEFINITION
6. The development of biosensors began in 1950, when a biosensors with an oxygen electrode (sometimes
described as Clark electrode) was developed by L. L. Clark in Cincinnati, USA to measure the dissolved
oxygen in blood.
Professor Leland C Clark 1918–2005
www.cuchd.in
FATHER OF BIOSENSOR
Fig 2. Father of Biosensor
7. Year Achievement
1975 First commercial biosensor (glucose biosensor)
1975 First microbial biosensor and immunosensor
1980 First optic biosensor
1984 First amperometric biosensor
1987 Blood glucose biosensor launched by
MediSense Exac Tech
1998 Blood Glucose biosensor launched by LifeScan
FastTake
Current Carbon nanotubes
IMPORTANT ACHIVEMENTS
8. • LINEARITY Linearity of the sensor should be high for the detection of high substrate
concentration.
• SENSITIVITY Value of the electrode response per substrate concentration.
• SELECTIVITY Chemicals Interference must be minimised for obtaining the correct result.
• RESPONSE TIME Time necessary for having 95% of the response.
BASIC CHARACTERSTICS OF
BIOSENSOR
9. •The SENSITIVE BIOLOGICAL MATERIAL a biologically derived material or biomimetic
component that interacts (binds or recognizes) the analyte under study. The biologically sensitive
elements can also be created by biological engineering.
•The TRANSDUCER or the DETECTOR ELEMENT that transforms the signal resulting from the
interaction of the analyte with the biological element into another signal (i.e., transduces) that can
be more easily measured and quantified.
•ASSOCIATED ELECTRONICS OR SIGNAL PROCESSORS .
•These are primarily responsible for the display of the results in a user-friendly way.
ELEMENTS/PARTS
11. The component used to bind the target molecule
Must be highly specific, stable under storage conditions, and immobilized
Microorganism
Tissue
Cell
Organelle
Nucleic Acid
Enzyme
Antibody
BIOLOGICAL ELEMENT
12. Acts as an interface measures the physical change that occurs with the reaction at the bioreceptor then
transforming that energy into measurable electrical output.
PRODUCT SENSOR
HEAT THERMISTOR
LIGHT OPTICAL TRANSDUCER
CURRENT ELECTROCHEMICAL TRANSDUCER
MASS PIEZOELECTRIC TRANSDUCER
TRANSDUCER
13. Signals from the transducer are passed to a microprocessor where they are amplified and analyzed
The data is then converted to concentration units and transferred to a display or/and data storage
device.
DETECTOR
15. • A sensory cell or organ which is responsive to chemical stimuli.
• Sensory Receptor (Taste bud receptor)
• Internal peripheral chemoreceptor
CHEMORECEPTORS
16. • Non specialized sense receptor that codes absolute and relative changes in temperature.
• Peripheral Nervous System have warmth receptors.
• Warmth receptors are unmylinated C- fibre receptors that respond to cold have mylinated C-
fibres
HOT AND COLD RECEPTORS
17. • These are pressure receptors are sensors located in the blood vessels that sense pressure of
blood in blood vessels.
• They sense the blood pressure and relay the information to the brain, so that a proper blood
pressure can be maintained.
• Two types:
• Arterial baroreceptors
• Low pressure baroreceptors
BARORECEPTORS
18. • Sensors for Smell are also called olfactory receptors which are located in nasal cavity.
• Olfactory receptor sense smell and give signal to brain and then it is possible to detect smell.
Sensors for vision
•Optical receptors are present in eyes
•Taste receptors are for taste
•Osmolarity receptors detect the osmolarity of blood and are found in hypothalamus
SENSORS FOR SMELL
20. Fig. 4 Monitors the glucose level in the
blood. .
Glucose monitoring device for
diabetes patients
21. Applications of Biosensor
Food Analysis
Study of biomolecules and their interaction
Drug Development
Crime detection
Medical diagnosis (both clinical and laboratory use)
Environmental field monitoring
Quality control
Industrial Process Control
Detection systems for biological warfare agents
Manufacturing of pharmaceuticals and replacement
organs
APPLICATIONS OF
BIOSENSOR