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Anatomy and
Physiology of Larynx
Dr. Krishna Koirala
2019-03-18
• Situated in the midline neck between 3rd - 6th
cervical vertebral level
• Consists of a framework of cartilages,
connected by ligaments and membranes,
lined by a mucous membrane and moved by
muscles
Anatomical components
–Cartilaginous skeleton
–Intrinsic muscles
–Extrinsic muscles
–Mucosal lining
Larynx (Anterior)
Larynx (Posterior)
Larynx (Posterior)
Larynx (Lateral)
Larynx (Superior)
Larynx (superior)
Larynx (sagittal section)
Larynx (sagittal section)
Larynx (coronal section)
Vocal fold
Vocal fold
Laryngeal Cartilages
Single (3) Paired (3)
Epiglottis Arytenoid
Thyroid Corniculate (cartilages of
Santorini)
Cricoid ( Signet ring like
cartilage)
Cuneiform (cartilages of
Wrisberg)
Cartilages (anterior)
Cartilages (posterior)
Cartilages (posterior)
Cartilage Histology
• Elastic
– Epiglottis, corniculate, cuneiform & apex of
arytenoid
– Little or no calcification
• Hyaline
– Thyroid, cricoid & remaining arytenoid
– Calcify as age advances
• Ossification begins by 25-30 yr & is completed by 60 yr
Indirect Laryngoscopy
Flexible Laryngoscopy
LEFT RIGHT
Laryngeal cavity
1. Laryngeal inlet
2. Laryngeal Vestibule
3. Laryngeal Ventricle
4. Rima glottis
5. Subglottis
Membranes & Ligaments
• Extrinsic
– Connect thyroid cartilage & epiglottis with hyoid
bone and cricoid cartilage with trachea
• Intrinsic
– Connect cartilages of larynx to each other
– Alter the position, shape and tension of the vocal
folds
Extrinsic
• Thyrohyoid
membrane
• Hyoepiglottic
ligament
• Cricotracheal
ligament
Intrinsic
1. Quadrangular membrane
 Aryepiglottic ligament , Vestibular ligament
2. Crico-vocal membrane
 Vocal ligament ,Cricothyroid membrane
3. Thyroepiglottic ligament
Anatomical Divisions
A. Supraglottis: laryngeal
inlet to apex of ventricle
B. Glottis: apex of ventricle to
10 mm below
C. Subglottis: lower glottic
border to lower cricoid
border
A. Supraglottis
- Epiglottis, Aryepiglottic folds ,Ventricular
bands ,Laryngeal ventricle
B. Glottis
-True vocal cords , Anterior commissure,
Posterior commissure
C. Subglottis
Intrinsic Muscles
A. Acting on vocal cords
• Abduction  Posterior crico - arytenoid
• Adduction  Lateral crico-arytenoid
Transverse inter-arytenoid
Thyro-arytenoid externa
• Tension + lengthening  Cricothyroid
• Relaxation + shortening  Vocalis
B. Acting on laryngeal inlet
Opener  Thyroepiglottic
Closer  Oblique inter-arytenoid,
Aryepiglottic
Extrinsic Muscles
• Primary Elevators Secondary Elevators
 Stylopharyngeus  Mylohyoid
 Salpingopharyngeus  Stylohyoid
 Palatopharyngeus  Geniohyoid
 Thyrohyoid  Digastric
• Depressors
– Sternohyoid  Sternothyroid  Omohyoid
Posterior cricoarytenoid
Lateral cricoarytenoid
Transverse Inter-arytenoid
Cricothyroid
Thyroarytenoid externa + Vocalis
Oblique Inter-arytenoid
Shape of Glottis
Shape of Glottis
Quiet Respiration Forced Inspiration
Inspiration
Shape of Glottis
Normal voice Whisper
Normal phonation
Whisper
Mucous Membrane
• Stratified squamous epithelium
– Epiglottis (anterior surface + upper half of
posterior surface), upper part of aryepiglottic folds
& vocal cords
• Pseudo-stratified ciliated columnar (respiratory)
epithelium
– Rest of laryngeal mucous membrane
Nerve Supply
• Superior Laryngeal Nerve
– Internal: sensation to supraglottis & glottis
– External: motor to cricothyroid muscle
• Recurrent Laryngeal Nerve
– Sensation to subglottis
– Motor to all intrinsic muscles but cricothyroid
Blood Supply
• Arterial supply
– Laryngeal b/o of superior & inferior thyroid
• Venous drainage
– Superior thyroid vein  internal jugular vein
– Inferior thyroid vein  innominate vein
Lymphatic Drainage
• Supraglottis: via thyrohyoid membrane into
upper deep cervical nodes & thyroid gland
• Subglottis: via cricothyroid membrane into
pretracheal + lower deep cervical nodes
• Glottis: has no lymphatics
Functions of Larynx
1. Protection of lower airway
2. Phonation (voice production)
3. Passage of air into lungs for respiration
4. Chest fixation by glottic closure
Protection of lower airway
• 3-level below-upward closure (Tier Mechanism)
– Vocal cords
– Ventricular bands
– Aryepiglottic folds
• Cessation of respiration
– Mediated by glossopharyngeal nv & deglutition
centre
• Cough reflex
Voice Production
1. Voice activating air reservoir in lungs -
affects voice intensity
2. Voice generation: affects voice pitch
3. Voice resonation: affects voice quality
4. Voice articulation: affects voice quality
Voice Production
Theories of voice production
• Puff Theory
– Puffs of air emitted through glottis
– Puffs of air set up vibratory activity of glottis
• Neurochronaxic Theory
– Each vibratory cycle initiated by nerve impulse to
vocalis muscle via recurrent/vagus nerve
– Frequency of voice dependent upon rate of
impulses delivered
• Aerodynamic Myoelastic Theory
Voice generation
• Aerodynamic myoelastic theory
– Vocal cords kept approximated  Subglottic blast
of air opens vocal cords from below upwards &
causes their passive vibration, producing sound 
Bernoulli's effect closes vocal cords below upwards
 Cycle repeated
Aerodynamic myoelastic theory (opening
phase)
Aerodynamic Myoelastic theory (closing
phase)
Voice generation
 High pitch = short, thin, tense
less elastic vocal cords
 Low pitch = long, bulky, relaxed,
More elastic vocal cords
 Falsetto voice = tense vocal cords
with small phonatory gap
Falsetto voice
Chest fixation
• Closure of glottis helps in raising intra-thoracic &
intra-abdominal pressure required for coughing ,
vomiting , defecation, micturition ,climbing , weight-
lifting , labour etc.

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