Prior to Louis Pasteur's work, there were two main theories about what caused disease: 1) Spontaneous generation - disease was caused by germs that spontaneously generated from decaying organic matter. 2) Miasma theory - disease was caused by "bad air" or poisonous vapors from rotting organic matter. Louis Pasteur's experiments with wine and silk worms helped disprove spontaneous generation and establish the germ theory of disease - that specific germs/microorganisms are the agents that cause specific diseases. Factors that contributed to Pasteur's discoveries included advances in microscope technology that allowed him to observe microorganisms, as well as experiments involving repeated tests and controls

1. Whatdidpeoplethinkcaused
disease1750-1900
Discuss&write
downasentence
toexplainall
images.

2. LO:Howdidscientistsdiscover
thatgermscausedisease.
All will be able to…identify what people thought caused disease prior
to Pasteur.
Most will be able to…describe the work of Louis Pasteur and germ
theory. (D)
Some will be able to…explain factors that were important in the
discovery of germ theory. (A)

3. SpontaneousGeneration…
• Spontaneous Generation - Disease was caused by germs
that were produced by flesh and vegetables as they rotted.
People believed that germs were the result of disease, not the
cause of it!
• Miasma – Disease was caused by bad air that was filled with
poisonous fumes from rotting matter.

4. VanLeeuwenhoek
• In 1677 – A clock maker from Holland,
Anthony van Leeuwenhoek, made a very
basic microscope. To his amazement, he
found tiny creatures moving about in nearly
all of the things he placed under his new
intervention. Found them in water droplets,
pepper, food and faeces. He called them
animalcules and published his findings.
Whatwerethese
animalcules…?
Drawasmallimageofthe
microscopeandexplainit…

5. LouisPasteur
WHO WAS HE?
• Born in France 1822. He studied chemistry
and biology, taking charge of science at Lille
University in 1854. It was his reputation as a
top chemist that first led one of Lille’s top
wine producers to go to Pasteur for help…
WHAT DID HE DO?
You each have a part of the story of Louis Pasteur…
You have 12 minutes to piece together the story of
Pasteur and complete your storyboard. You must
educate rather than copy …

6. Pasteur…
Once you have completed your storyboard…
- Summarise what germ theory is in your own words.
- EXT: What factors were involved in Pasteur's discovery?
Think! What factors have we looked at else where in the course
(Jenner, how many times was the experiment repeated…)
Think! What role does ‘industry’ play (i.e. the silk company)?

7. Factors…

8. AllWriteConsensus…
• You now have 6 minutes to discuss an answer to the following
question in your groups of four. After the 6 minutes you will write
the same answer that you have discussed to the question in your
own style.
• What factors affected Pasteur’s development of the germ theory?
(12 marks).
Link the factors to how they helped develop Pasteur's
work. You can’t write about them all, choose a couple to focus on.
Group One – Lenny, Tom B, Alice, Amarilda.
Group Two – Chelsea, Ellie, Liam W, Branden.
Group Three – Max, Rebecca, Alice, Kira.
Group Four – Connor, Joe, Shannon, Johnny.
Group Five - Georgia, Asiatu, Tom H, Sophie.

9. PeerAssess
- Answer makes general comments on the germ theory. 1-4
- Answer describes one factor such as the role of technology
leading to improvements in the microscope. 5-8
- Answer includes some explanation of various factors such as
scientific methods and clearly explains how these helped in
the development of the germ theory. 9-12
WWW – What Went Well – Look at my comments as a guide…
EBI – Even Better If – Look at my comments as a guide…

10. Summarise…
• Summarise something that you have learnt in today’s lesson
using the Play-Doh provided…
• You have 5 minutes… it can be abstract.
Prepare to Share