Presentation given at H+ 2011 Melbourne which turned out to be much about problem merging terminology from independent silo-based framings of complexity theory.
Excellent Literary Criticism Essay ThatsnotusLisa Brown
The document discusses creating an authoring system for live electronic music performances that simplifies the compositional workflow and aids in performance. It proposes extending common Western music notation to represent the underlying logic and electronic parts. This would involve developing an authoring/performance technology environment to represent and execute the logical layer of pieces, allowing composers to create live electronic works and evaluate the system. The goal is to integrate this new notation organically with traditional music interpretation while using common Western notation as the main descriptor due to its widespread use among composers.
1) Modern physics and science have discovered that the universe is fundamentally holographic and interconnected, rather than a collection of separate objects.
2) Pioneering scientists like Bohm and Pribram proposed that reality is holographic, with the properties of the whole contained in every part.
3) If the nature of reality is truly holographic, it suggests that consciousness plays a role in constructing physical reality and that our thoughts can directly influence worldly outcomes.
The document discusses creating a Manifesto of Light based on a round table discussion in Ecuador. It provides quotes about imagination, paradigm shifts through crisis, controlling perception to control reality, the power of human consciousness and intention, seeing beyond limitations, and creating positive change through compassion. The discussion focuses on using love to transform political structures from within by rebuilding society's fabric in favor of compassionate governance.
1. The document discusses the nature of perception and consciousness. It argues that reality is constructed by the perceiver and different perceivers, like humans and ants, perceive different realities based on their cognitive abilities.
2. Living beings are defined by their ability to process energy and information to interact with their environments. Brains evolved to perform fast simulations to predict the future behavior of nonlinear systems.
3. Human consciousness uniquely evolved through tools, language, culture and civilization. Religions, art, science emerged from human capacities for reasoning, creativity and questioning authority.
Short Hindi Essay On Raksha Bandhan. Online assignment writing service.Shannon Holt
The document provides instructions for creating an account and submitting a request for an assignment writing service on the website HelpWriting.net. It outlines a 5-step process: 1) Create an account with an email and password. 2) Complete a 10-minute order form providing instructions, sources, and deadline. 3) Review bids from writers and choose one based on qualifications. 4) Review the completed paper and authorize payment. 5) Request revisions to ensure satisfaction, with a refund offered for plagiarized work. The service aims to provide original, high-quality content meeting customers' needs.
Short Hindi Essay On Raksha Bandhan. Online assignment writing service.Christine Muller
This document provides instructions for seeking writing help from HelpWriting.net in 5 steps:
1. Create an account with a password and email.
2. Complete a 10-minute order form with instructions, sources, and deadline.
3. Review bids from writers and choose one based on qualifications.
4. Review the paper and authorize payment if pleased, or request revisions.
5. Choose HelpWriting.net confidently knowing your needs will be fully met.
An Introduction to Philosophy
Lecture 06: Moral Philosophy
James Mooney
Open Studies
The University of Edinburgh
j.mooney@ed.ac.uk
www.filmandphilosophy.com
@film_philosophy
Presentation given at H+ 2011 Melbourne which turned out to be much about problem merging terminology from independent silo-based framings of complexity theory.
Excellent Literary Criticism Essay ThatsnotusLisa Brown
The document discusses creating an authoring system for live electronic music performances that simplifies the compositional workflow and aids in performance. It proposes extending common Western music notation to represent the underlying logic and electronic parts. This would involve developing an authoring/performance technology environment to represent and execute the logical layer of pieces, allowing composers to create live electronic works and evaluate the system. The goal is to integrate this new notation organically with traditional music interpretation while using common Western notation as the main descriptor due to its widespread use among composers.
1) Modern physics and science have discovered that the universe is fundamentally holographic and interconnected, rather than a collection of separate objects.
2) Pioneering scientists like Bohm and Pribram proposed that reality is holographic, with the properties of the whole contained in every part.
3) If the nature of reality is truly holographic, it suggests that consciousness plays a role in constructing physical reality and that our thoughts can directly influence worldly outcomes.
The document discusses creating a Manifesto of Light based on a round table discussion in Ecuador. It provides quotes about imagination, paradigm shifts through crisis, controlling perception to control reality, the power of human consciousness and intention, seeing beyond limitations, and creating positive change through compassion. The discussion focuses on using love to transform political structures from within by rebuilding society's fabric in favor of compassionate governance.
1. The document discusses the nature of perception and consciousness. It argues that reality is constructed by the perceiver and different perceivers, like humans and ants, perceive different realities based on their cognitive abilities.
2. Living beings are defined by their ability to process energy and information to interact with their environments. Brains evolved to perform fast simulations to predict the future behavior of nonlinear systems.
3. Human consciousness uniquely evolved through tools, language, culture and civilization. Religions, art, science emerged from human capacities for reasoning, creativity and questioning authority.
Short Hindi Essay On Raksha Bandhan. Online assignment writing service.Shannon Holt
The document provides instructions for creating an account and submitting a request for an assignment writing service on the website HelpWriting.net. It outlines a 5-step process: 1) Create an account with an email and password. 2) Complete a 10-minute order form providing instructions, sources, and deadline. 3) Review bids from writers and choose one based on qualifications. 4) Review the completed paper and authorize payment. 5) Request revisions to ensure satisfaction, with a refund offered for plagiarized work. The service aims to provide original, high-quality content meeting customers' needs.
Short Hindi Essay On Raksha Bandhan. Online assignment writing service.Christine Muller
This document provides instructions for seeking writing help from HelpWriting.net in 5 steps:
1. Create an account with a password and email.
2. Complete a 10-minute order form with instructions, sources, and deadline.
3. Review bids from writers and choose one based on qualifications.
4. Review the paper and authorize payment if pleased, or request revisions.
5. Choose HelpWriting.net confidently knowing your needs will be fully met.
An Introduction to Philosophy
Lecture 06: Moral Philosophy
James Mooney
Open Studies
The University of Edinburgh
j.mooney@ed.ac.uk
www.filmandphilosophy.com
@film_philosophy
- René Descartes was a seminal 17th century French philosopher, mathematician, and scientist. He is famous for connecting geometry and algebra, establishing the theory of innate knowledge, and resolving the problem of personal existence through his famous statement "I think, therefore I am."
- Immanuel Kant was an influential 18th century German philosopher considered a central figure of the Enlightenment. He argued that we can only have knowledge of things we can experience and is known for his categorical imperative which states we should only act in accordance with universal principles.
- Both philosophers believed in free will and its importance. Descartes linked freedom of the will to bearing the image of God while Kant stated a free will and one acting under moral law
The document provides instructions for submitting an assignment request to the website HelpWriting.net. It outlines a 5-step process: 1) Create an account with an email and password. 2) Complete a 10-minute order form with instructions, sources, and deadline. 3) Review bids from writers and choose one. 4) Review the completed paper and authorize payment. 5) Request revisions until satisfied with the work.
Based on Berkun's as well as many other books, this is a brief introduction to some misconceptions about innovation. Presentación en el curso de Innovación del ITESM campus Querétaro
The document provides steps for requesting writing assistance from HelpWriting.net. It outlines the registration process, how to submit a request including instructions and deadline, and how writers bid on requests. It also describes reviewing bids, selecting a writer, making a deposit, and reviewing and authorizing payment for the completed work. Revisions are available and a refund is offered if plagiarism occurs.
A philosophical inquiry presented to students to assist in developing truth seeking, questioning and skepticism when filtering information from various media sources.
Five Paragraph Persuasive Essay SampleAmy Toukonen
The document provides a 3 paragraph summary of Louis Berkof's book "Introduction to the New Testament". It discusses how Berkof systematically addresses the origin, content, characteristics, authorship, composition and canonical significance of the Gospels and Epistles. The summary aims to ensure an accurate understanding of the New Testament within its correct historical setting. Berkof primarily wrote the book for his students at Calvin Theological Seminary where he taught for 30 years. The summary incorporates the research of past scholars and church fathers to present a diverse overview of the introduction to the New Testament.
The Brain - Part 6 of Piero Scaruffi's class "Thinking about Thought" at UC B...piero scaruffi
The Brain - Part 6 of Piero Scaruffi's class "Thinking about Thought" at UC Berkeley (2014). I keep updating this presentation at www.scaruffi.com/ucb.html
This document provides information about creativity and creative thinking. It defines creativity as the ability to produce novel and useful ideas or work. It discusses different types of creativity and lists steps involved in creative thinking. It also outlines tests that are used to measure creativity, such as unusual uses tests and remote associates tests. Finally, it discusses obstacles to creativity such as perceptual, cultural and emotional blocks.
The document discusses "The Secret", which is described as an infinite power or law of attraction that has been known throughout history. It states that thoughts become things through the law of attraction, and that positive thoughts and feelings attract positive experiences and outcomes into one's life, while negative thoughts attract negative experiences. Readers are encouraged to visualize their desires, be grateful for what they have, and feel positive emotions to manifest improvements in their health, wealth, relationships and more. The Secret is presented as the key to creating the life you want through harnessing the power of your mind.
Everything is an illusion. - Do we live in a computer simulation?Harshal Hayatnagarkar
In the words of legendary science fiction writer Arthur C Clarke, "Any sufficiently advanced technology is indistinguishable from magic." In last few hundred years, we humans have made great progress in science and technology . With computing innovations, the pace of progress is rather accelerating, and will leave a lasting impact on us as a species.
Transhumanism is an intellectual movement to study this impact, and aims to enhance physical, psychological, and intellectual potential to leap into a posthuman era. In this talk, we will discuss a speculative idea from transhumanism, where even the magic is real.
The document discusses thinking outside the box and creative thinking. It suggests that the box, which represents conformity and limiting habits, is made up of six sides: limiting assumptions, addiction to the status quo, hyper-rationality, tunnel vision, intolerance for ambiguity, and no intrinsic motivation. It encourages the reader to identify which side most limits their thinking and to take action to expand beyond that boundary in their work. The document provides quotes and questions to inspire creative approaches.
The document discusses thinking outside the box and creative thinking. It suggests that the box, which represents conformity and limitation, is made up of six sides: limiting assumptions, addiction to the status quo, hyper-rationality, tunnel vision, intolerance for ambiguity, and no intrinsic motivation. It encourages taking steps to overcome the side of the box that is most limiting and applying creative thinking to projects.
This document summarizes key concepts in ethics, including:
1) Meta-ethics addresses questions about the nature of ethics, normative ethics focuses on moral standards and principles, and applied ethics applies theory to practical issues like abortion and war.
2) Objectivism holds that values exist independently of human views while subjectivism says values are human constructs. Absolutism and relativism differ on whether morality is universal or culturally dependent.
3) Deontology judges acts by their adherence to duty while consequentialism assesses acts by their outcomes. Utilitarianism specifically aims to maximize happiness. Virtue ethics focuses on developing good character rather than rules.
The document provides instructions for requesting writing assistance from the website HelpWriting.net. It outlines a 5-step process: 1) Create an account with a password and email. 2) Complete an order form with instructions, sources, and deadline. 3) Review bids from writers and select one. 4) Review the completed paper and authorize payment. 5) Request revisions until satisfied with the work. It emphasizes that original, plagiarism-free content will be provided, with refunds offered for plagiarized work.
Youm E Azadi Essay In English. Online assignment writing service.Joanna Gardner
The document provides instructions for using a writing assistance service in 5 steps: 1) Create an account with valid email and password. 2) Complete a 10-minute order form providing instructions, sources, and deadline. 3) Review bids from writers and choose one based on qualifications. 4) Review the completed paper and authorize payment if satisfied. 5) Request revisions to ensure needs are fully met.
The document discusses the history and development of artificial intelligence. It defines AI as making computers do things that people are better at, like extending capabilities to large data or making fewer mistakes. Early AI research focused on games, mathematics, and knowledge-based systems. Over time, the focus shifted to symbolic and subsymbolic approaches, as well as robotics, language processing, and machine learning. Knowledge representation and commonsense reasoning remain challenging areas of research.
The document discusses the concept of the "Medici Effect" where intersecting different fields, disciplines, or cultures can produce extraordinary new ideas. It explains that intersectional innovations occur at the intersection of disciplines and encourages finding ways to break down barriers between fields through diversity, randomness, and generating many ideas. The key is to step into the intersection of different areas in order to innovate and help create the future.
The document provides 12 tips for generating new ideas:
1. Chase down ideas immediately and write them down.
2. Embrace observation and the "anthropologist persona" to gain insights from observing others.
3. Ask relevant questions to better understand problems and opportunities.
4. Weigh pursuing ideas you're passionate about despite fears of criticism.
5. Take walks in nature to relax and spark ideas.
6. Change your perspective by looking at problems through different "lenses".
7. Don't dismiss "insane" ideas that could become breakthrough innovations.
8. Meet people outside your normal circles to access diverse perspectives.
9. Do novel activities to break routines and see
This document provides an overview of Prader-Willi syndrome, a genetic disorder characterized by mental retardation, short stature, low muscle tone, incomplete sexual development, and an intense, insatiable desire to eat. The syndrome was first described in 1956 by three Swiss doctors and is caused by the absence of certain genes on chromosome 15. People with Prader-Willi syndrome experience constant hunger and obesity, which can lead to serious health problems if not carefully managed.
This document summarizes a presentation about innovation and creativity for fundraisers. It discusses the importance of innovation, where good ideas come from, and ways to generate new ideas such as asking "what if?" and seeing things from other perspectives. The presentation encourages participants to make connections, take risks with new ideas, and to take action by writing down one new thing they will try.
NDCT Rules, 2019: An Overview | New Drugs and Clinical Trial Rules 2019Akash Agnihotri
The New Drugs and Clinical Trials Rules, 2019 (NDCT Rules, 2019) apply to all new drugs, investigational new drugs for human use, clinical trials, bioequivalence studies, bioavailability studies, and ethics committees. The rules also apply to orphan drugs, phytopharmaceutical drugs, and biomedical and health research.
Pharmacodynamics of Drugs: Introduction to PharmacologyAkash Agnihotri
Pharmacodynamics is one the basic unit to understand the pharmacology subject.
Pharmacodynamics (sometimes described as what a drug does to the body) is the study of the biochemical, physiologic, and molecular effects of drugs on the body and involves receptor binding (including receptor sensitivity), postreceptor effects, and chemical interactions.
This ppt will be helpful for MBBS, Pharmacy, and Nursing Students.
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Similar to 10 Concepts that explains the modern world
- René Descartes was a seminal 17th century French philosopher, mathematician, and scientist. He is famous for connecting geometry and algebra, establishing the theory of innate knowledge, and resolving the problem of personal existence through his famous statement "I think, therefore I am."
- Immanuel Kant was an influential 18th century German philosopher considered a central figure of the Enlightenment. He argued that we can only have knowledge of things we can experience and is known for his categorical imperative which states we should only act in accordance with universal principles.
- Both philosophers believed in free will and its importance. Descartes linked freedom of the will to bearing the image of God while Kant stated a free will and one acting under moral law
The document provides instructions for submitting an assignment request to the website HelpWriting.net. It outlines a 5-step process: 1) Create an account with an email and password. 2) Complete a 10-minute order form with instructions, sources, and deadline. 3) Review bids from writers and choose one. 4) Review the completed paper and authorize payment. 5) Request revisions until satisfied with the work.
Based on Berkun's as well as many other books, this is a brief introduction to some misconceptions about innovation. Presentación en el curso de Innovación del ITESM campus Querétaro
The document provides steps for requesting writing assistance from HelpWriting.net. It outlines the registration process, how to submit a request including instructions and deadline, and how writers bid on requests. It also describes reviewing bids, selecting a writer, making a deposit, and reviewing and authorizing payment for the completed work. Revisions are available and a refund is offered if plagiarism occurs.
A philosophical inquiry presented to students to assist in developing truth seeking, questioning and skepticism when filtering information from various media sources.
Five Paragraph Persuasive Essay SampleAmy Toukonen
The document provides a 3 paragraph summary of Louis Berkof's book "Introduction to the New Testament". It discusses how Berkof systematically addresses the origin, content, characteristics, authorship, composition and canonical significance of the Gospels and Epistles. The summary aims to ensure an accurate understanding of the New Testament within its correct historical setting. Berkof primarily wrote the book for his students at Calvin Theological Seminary where he taught for 30 years. The summary incorporates the research of past scholars and church fathers to present a diverse overview of the introduction to the New Testament.
The Brain - Part 6 of Piero Scaruffi's class "Thinking about Thought" at UC B...piero scaruffi
The Brain - Part 6 of Piero Scaruffi's class "Thinking about Thought" at UC Berkeley (2014). I keep updating this presentation at www.scaruffi.com/ucb.html
This document provides information about creativity and creative thinking. It defines creativity as the ability to produce novel and useful ideas or work. It discusses different types of creativity and lists steps involved in creative thinking. It also outlines tests that are used to measure creativity, such as unusual uses tests and remote associates tests. Finally, it discusses obstacles to creativity such as perceptual, cultural and emotional blocks.
The document discusses "The Secret", which is described as an infinite power or law of attraction that has been known throughout history. It states that thoughts become things through the law of attraction, and that positive thoughts and feelings attract positive experiences and outcomes into one's life, while negative thoughts attract negative experiences. Readers are encouraged to visualize their desires, be grateful for what they have, and feel positive emotions to manifest improvements in their health, wealth, relationships and more. The Secret is presented as the key to creating the life you want through harnessing the power of your mind.
Everything is an illusion. - Do we live in a computer simulation?Harshal Hayatnagarkar
In the words of legendary science fiction writer Arthur C Clarke, "Any sufficiently advanced technology is indistinguishable from magic." In last few hundred years, we humans have made great progress in science and technology . With computing innovations, the pace of progress is rather accelerating, and will leave a lasting impact on us as a species.
Transhumanism is an intellectual movement to study this impact, and aims to enhance physical, psychological, and intellectual potential to leap into a posthuman era. In this talk, we will discuss a speculative idea from transhumanism, where even the magic is real.
The document discusses thinking outside the box and creative thinking. It suggests that the box, which represents conformity and limiting habits, is made up of six sides: limiting assumptions, addiction to the status quo, hyper-rationality, tunnel vision, intolerance for ambiguity, and no intrinsic motivation. It encourages the reader to identify which side most limits their thinking and to take action to expand beyond that boundary in their work. The document provides quotes and questions to inspire creative approaches.
The document discusses thinking outside the box and creative thinking. It suggests that the box, which represents conformity and limitation, is made up of six sides: limiting assumptions, addiction to the status quo, hyper-rationality, tunnel vision, intolerance for ambiguity, and no intrinsic motivation. It encourages taking steps to overcome the side of the box that is most limiting and applying creative thinking to projects.
This document summarizes key concepts in ethics, including:
1) Meta-ethics addresses questions about the nature of ethics, normative ethics focuses on moral standards and principles, and applied ethics applies theory to practical issues like abortion and war.
2) Objectivism holds that values exist independently of human views while subjectivism says values are human constructs. Absolutism and relativism differ on whether morality is universal or culturally dependent.
3) Deontology judges acts by their adherence to duty while consequentialism assesses acts by their outcomes. Utilitarianism specifically aims to maximize happiness. Virtue ethics focuses on developing good character rather than rules.
The document provides instructions for requesting writing assistance from the website HelpWriting.net. It outlines a 5-step process: 1) Create an account with a password and email. 2) Complete an order form with instructions, sources, and deadline. 3) Review bids from writers and select one. 4) Review the completed paper and authorize payment. 5) Request revisions until satisfied with the work. It emphasizes that original, plagiarism-free content will be provided, with refunds offered for plagiarized work.
Youm E Azadi Essay In English. Online assignment writing service.Joanna Gardner
The document provides instructions for using a writing assistance service in 5 steps: 1) Create an account with valid email and password. 2) Complete a 10-minute order form providing instructions, sources, and deadline. 3) Review bids from writers and choose one based on qualifications. 4) Review the completed paper and authorize payment if satisfied. 5) Request revisions to ensure needs are fully met.
The document discusses the history and development of artificial intelligence. It defines AI as making computers do things that people are better at, like extending capabilities to large data or making fewer mistakes. Early AI research focused on games, mathematics, and knowledge-based systems. Over time, the focus shifted to symbolic and subsymbolic approaches, as well as robotics, language processing, and machine learning. Knowledge representation and commonsense reasoning remain challenging areas of research.
The document discusses the concept of the "Medici Effect" where intersecting different fields, disciplines, or cultures can produce extraordinary new ideas. It explains that intersectional innovations occur at the intersection of disciplines and encourages finding ways to break down barriers between fields through diversity, randomness, and generating many ideas. The key is to step into the intersection of different areas in order to innovate and help create the future.
The document provides 12 tips for generating new ideas:
1. Chase down ideas immediately and write them down.
2. Embrace observation and the "anthropologist persona" to gain insights from observing others.
3. Ask relevant questions to better understand problems and opportunities.
4. Weigh pursuing ideas you're passionate about despite fears of criticism.
5. Take walks in nature to relax and spark ideas.
6. Change your perspective by looking at problems through different "lenses".
7. Don't dismiss "insane" ideas that could become breakthrough innovations.
8. Meet people outside your normal circles to access diverse perspectives.
9. Do novel activities to break routines and see
This document provides an overview of Prader-Willi syndrome, a genetic disorder characterized by mental retardation, short stature, low muscle tone, incomplete sexual development, and an intense, insatiable desire to eat. The syndrome was first described in 1956 by three Swiss doctors and is caused by the absence of certain genes on chromosome 15. People with Prader-Willi syndrome experience constant hunger and obesity, which can lead to serious health problems if not carefully managed.
This document summarizes a presentation about innovation and creativity for fundraisers. It discusses the importance of innovation, where good ideas come from, and ways to generate new ideas such as asking "what if?" and seeing things from other perspectives. The presentation encourages participants to make connections, take risks with new ideas, and to take action by writing down one new thing they will try.
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NDCT Rules, 2019: An Overview | New Drugs and Clinical Trial Rules 2019Akash Agnihotri
The New Drugs and Clinical Trials Rules, 2019 (NDCT Rules, 2019) apply to all new drugs, investigational new drugs for human use, clinical trials, bioequivalence studies, bioavailability studies, and ethics committees. The rules also apply to orphan drugs, phytopharmaceutical drugs, and biomedical and health research.
Pharmacodynamics of Drugs: Introduction to PharmacologyAkash Agnihotri
Pharmacodynamics is one the basic unit to understand the pharmacology subject.
Pharmacodynamics (sometimes described as what a drug does to the body) is the study of the biochemical, physiologic, and molecular effects of drugs on the body and involves receptor binding (including receptor sensitivity), postreceptor effects, and chemical interactions.
This ppt will be helpful for MBBS, Pharmacy, and Nursing Students.
Pharmacokinetics of Drugs: Introduction to PharmacologyAkash Agnihotri
Pharmacokinetics of drugs is the study of (ADME) Absorption, Distribution, Metabolims, and Excretion.
Pharmacokinetics is all about understanding how drugs move, change, and leave the body.
This is one of the basic unit of pharmacology, to understand the subject pharmacology.
This ppt will be use for MBBS, Nursing and Pharmacy students.
Receptor desensitization and regulation of receptors,Diseases resulting from...Akash Agnihotri
Receptor desensitization and regulation of receptors,Diseases resulting from receptor and pathway dysfunction, Physiological systems Integrated multiple signals
Safety pharmacology aims to identify adverse effects of drugs prior to clinical trials through guidelines established by the ICH. The antihistamine terfenadine was found to cause a rare but lethal cardiac effect and highlighted the need for improved preclinical safety testing. Safety pharmacology studies objectives are to detect undesirable pharmacodynamic properties and adverse effects observed in toxicology and help inform decisions about beginning human testing. A variety of in vitro and ex vivo methods are recommended including isolated tissue and cell-based assays, and zebrafish and stem cell models to comprehensively evaluate a new drug's safety profile.
Drugs Used in Heart Failure
Drugs without positive inotropic effects used in Heart Failure:
Diuretics
ACE/ARB & Related agents
Vasodilators
β-Adrenergic Blockers
Others
Drugs with positive inotropic effects used in Heart Failure:
Digitalis
Other positive inotropic drugs:
Bipyridines
Beta-Adrenergic agonists
Investigational positive inotropic drugs: Istaroxime, Levosimanden, Omecamtiv mecarbil
This document summarizes information about histamine, serotonin, and ergot alkaloids. It discusses their structures, physiological roles as neurotransmitters or hormones, receptor types, and mechanisms of action. It also describes clinical uses of antihistamines, serotonin agonists and antagonists, and ergot alkaloids in conditions like allergies, migraine, nausea, and postpartum hemorrhage. Key points covered include the four types of histamine receptors (H1-H4), serotonin's seven receptor families (5-HT1-7), and how ergot alkaloids structurally resemble biogenic amines and affect various receptors.
National List of Essential Meidicne 2022 by DrugsInfoAkash Agnihotri
Dr Mansukh Mandaviya launches National Lists of Essential Medicines (NLEM) 2022
384 Drugs included in NLEM 2022; 34 new drugs added
“Under Hon. PM’s vision of Sabko Dawai, Sasti Dawai NLEM another step towards affordable healthcare with reduced Out-of-Pocket-Expenditure (OOPE)”
It will further ensure efficacy, safety, quality, affordability and accessibility of medicines: Dr Mansukh Mandaviya
Caffeine-Pharmacology and other info by DrugsInfoAkash Agnihotri
It's is all you need to know about caffeine. All the information available in this ppt, made by authenticated sources. That is following evidence-based medicine process.
Follow @drugs_info_ on Instagram
@drugsinfo01 on facebook and
youtube/DrugsInfo
Animal models for screening agents useful in Heart FailureAkash Agnihotri
This ppt will give you all information about various animal models for screening of drugs that are useful in the treatment of heart failure. This ppt is made by various authenticated research articles and books.
ppt include-
In-vivo models:
1. Rat models
2. Dog models
3. Rabbit models
4. Guinea pig models
5. Syrian hamster models
6. Murine models
7. Zebrafish models
8. Swine models
9. Transgenic mice
10. Other models (22 other models)
In-vitro models:
1. Isolated hamster cardiomyopathic heart
2. Isolated cat papillary muscle
3. Ouabain binding
YouTube Channel Link for drug information:
https://www.youtube.com/channel/UC49iKtopfbsV3ggHy7pmAug/about
Adrenergic Agonist & Sympathomimetic Drugs.
It includes:
Sympathetic Nervous System
Structures of the major catecholamines
Drugs acting at adrenergic neurons
Structure-Activity Relationship of sympathomimetic Amines
Structure & main clinical use of important sympathomimetic drugs
Adrenergic Receptors: Types, Nomenclature
Sympathomimetic drugs (with Recent Advances)
Beta-adrenergic blockers as a potential treatment for COVID-19 patients
Summary
Functional Organization of Autonomic ActivityAkash Agnihotri
This slide including Functional Organization of Autonomic Activity
A little intro about ANS
Then Organization of the nervous system including
Afferent/Efferent: Transmission
Somatic and Autonomic Nervous system
Sympathetic and Parasympathetic nervous system
Enteric nervous system
Their functions, differences in between functions and organization with some tables and figures
Then, the Role of the CNS in the control of autonomic functions
with example
Then, presynaptic modulation and postsynaptic modulation
Also, Innervations by the ANS
And lastly Transmitters other than acetylcholine and noradrenaline
Transporter superfamilies in the human genomeAkash Agnihotri
This document summarizes transporter superfamilies in the human genome. It discusses the two main superfamilies - solute carrier (SLC) and ATP-binding cassette (ABC) transporters. The SLC superfamily includes 52 families and around 395 genes encoding mostly facilitative transporters. The ABC superfamily includes 7 families with 49 genes encoding active transporters that use ATP hydrolysis to transport substrates against gradients. Key transporters from these families play important roles in drug absorption, distribution, and elimination. Polymorphisms in various transporters have been associated with human diseases and drug interactions.
'Basic mechanisms of membrane transport is the topic of general pharmacology.
Introduction- Membrane Transport
Plasma Membrane
Lipid solubility in membrane permeation
Transporters Versus Channels
Mechanisms of Transport
Passive Diffusion
Relationship between Molecular weight and Diffusion
Carrier mediated Transport
Facilitated Diffusion
Active Transport
Primary Active Transport
P type- Na+ K+-ATPase
Secondary Active transport- Symport, Antiport
Intestinal Transporters with e.g
Vesicular Transport-Exocytosis, Endocytosis-Phagocytosis,Pinocytosis
Pore (Convective) Transport
Ion Pair Formation
Absorption- Extent and Rate (Bioavailability)
MCQ Answers- 1. C (Largely hydrophobic, yet soluble in aqueous solutions)- Lippincott
2. B (Oral)- KDT
3. C (Is incompletely absorbed)-KDT
Content:
Absorption- via gastrointestinal tract
Absorption- via Parenteral sites
Absorption- via Lungs
Extent and Rate of Absorption- Why?
Bioavailability (with formula)
Concept of Bioavailability
Extent of absorption
First-pass elimination (with Extraction ratio formula)
Rate of absorption
Rate and extent of absorption (bioavailability)
Measurement of bioavailability
Factor influencing bioavailability
Multiple Choice Questions.
The document discusses key concepts in pharmacokinetics including drug formulation, absorption, distribution, metabolism, and elimination. It provides information on oral and parenteral drug administration routes and factors that influence drug permeation and distribution in the body. Graphs are presented on relative organ volumes and blood flow, drug binding sites on human plasma albumin, and the relationship between volume of distribution, plasma concentration, and half-life. An example drug for stroke treatment, NXY-059, is also mentioned.
Recent Advances in pharmacotherapy of Respiratory DisordersAkash Agnihotri
Akash Agnihotri presented on mechanisms of asthma and pathophysiology of pulmonary diseases. He discussed the mechanism of asthma including inflammation and airway narrowing. He also reviewed the pathophysiology of idiopathic pulmonary fibrosis and pulmonary arterial hypertension. Finally, he listed drugs used to treat pulmonary arterial hypertension, noting their FDA approval status.
Procrastination is a common challenge that many individuals face when it comes to completing tasks and achieving goals. It can hinder productivity and lead to feelings of stress and frustration.
However, with the right strategies and mindset, it is possible to overcome procrastination and increase productivity.
In this article, we will explore the causes of procrastination, how to recognize the signs of procrastination in oneself, and effective strategies for overcoming procrastination and boosting productivity.
Aggression - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
You may be stressed about revealing your cancer diagnosis to your child or children.
Children love stories and these often provide parents with a means of broaching tricky subjects and so the ‘The Secret Warrior’ book was especially written for CANSA TLC, by creative writer and social worker, Sally Ann Carter.
Find out more:
https://cansa.org.za/resources-to-help-share-a-parent-or-loved-ones-cancer-diagnosis-with-a-child/
As we navigate through the ebbs and flows of life, it is natural to experience moments of low motivation and dwindling passion for our goals.
However, it is important to remember that this is a common hurdle that can be overcome with the right strategies in place.
In this guide, we will explore ways to rekindle the fire within you and stay motivated towards your aspirations.
Understanding of Self - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
ProSocial Behaviour - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
2. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 2
3. Parkinson’s Law
Parkinson's law is an axiom that states,
"Work expands so as to fill the time
available for its completion". The term
was coined by Cyril Northcote
Parkinson in a humorous essay he
wrote for “The Economist” in 1955.
Prepared by: Akash Agnihotri
3
4. Interesting Stress Curver
Parkinson's law is an axiom that states,
"Work expands so as to fill the time
available for its completion". The term
was coined by Cyril Northcote
Parkinson in a humorous essay he
wrote for “The Economist” in 1955.
Work expands so as to fill the time available for its
completion Prepared by: Akash Agnihotri 4
5. Parkinson’s Law can mean:
• Things become harder to complete when more
time is given to complete it.
• You take longer than necessary to complete a
task or you procrastinate and complete the task
right before the due date.
• The amount of work required for something
increases so that it consumes any amount of
that may be allotted to it.
• The duration of public administration,
bureaucracy, and officialdom expands to fill its
allotted time span, regardless of the amount of
work to be done.
• The number of subordinates increases at a fixed
rate regardless of the amount of work produced.
Prepared by: Akash Agnihotri 5
6. Parkinson’s Law Example:
• Companies become bigger and worse over
time. Clerks manufacture work for each
other as overall capacity dips. When British
Navy ships went down from 68 to 20,
officials increased by 78%.
Prepared by: Akash Agnihotri 6
9. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 9
10. Chesterton’s Fence
Chesterton's Fence is a principle that
says you should not make changes until
you understand the reasoning behind
the current state of affairs.
It was coined by English author and
journalist G. K. Chesterton in his 1929
book The Thing: Why I Am a Catholic..
Prepared by: Akash Agnihotri 10
11. Chesterton’s Fence:
Principle says that
• Things Change should not be made until the
reasoning behind the current state of affairs is
understood
• Understanding the rationale behind previous
decisions is a core component of making great
decisions
• If we don't understand how we got “here,” we
run the risk of making things much worse
Prepared by: Akash Agnihotri 11
12. Chesterton’s Fence
If you don’t know what an old
custom does, don’t touch it. It may
be holding back problems you’re
completely unaware of. You’ve not
seen the wolves yet because of the
very fence you’re about to
demolish.
Prepared by: Akash Agnihotri 12
13. Next Concepts
•The Medici Effect
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Prepared by: Akash Agnihotri 13
15. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 15
16. The Medici Effect
The Medici effect is the idea that
diversity leads to increased creativity
and innovation.
The term comes from a book of the
same name by Frans Johansson.
Prepared by: Akash Agnihotri 16
17. The Medici Effect
• The Medici effect explains how innovation
happens when ideas and people from different
fields collaborate.
• Also, shows how breakthrough ideas often occur
when concepts from one field are brought into a
new, unfamiliar territory.
• It also offers examples of how to turn ideas into
path-breaking innovations.
Prepared by: Akash Agnihotri 17
18. The Medici Effect outlines four
steps
•Expose yourself to a range of
cultures.
•Brainstorm solutions to problems
with a diverse group of thinkers.
•Break away from entrenched ways
of thinking.
•Look for radical solutions that may
change lives.
Prepared by: Akash Agnihotri 18
19. The Medici Effect
Sculptors, painters, and architects
converged in Florence as the
Medici were funding the artists.
Their proximity led to a fertile
dialogue which, in turn, led to the
Renaissance. The internet will
amplify this cross-pollination of
ideas.
Prepared by: Akash Agnihotri 19
22. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 22
23. The Centipede’s Dilemma
"The Centipede's Dilemma" is a short
poem that describes a psychological
effect called the centipede effect or
centipede syndrome.
The centipede effect occurs when a
normally automatic or unconscious
activity is disrupted by conscious
thought of it.
For example, players and sportsmen
who think too closely about their actions
can find their performance impaired.
Prepared by: Akash Agnihotri 23
24. The Centipede’s Dilemma
• The poem is about how thinking too much about
something you normally do can make it difficult
to perform the task.
• For example, "A centipede was happy - quite!
Said, 'Pray, which leg moves after which?' Not
knowing how to run".
Prepared by: Akash Agnihotri
25. The Centipede’s Dilemma
•The moral of the story "The
Centipede" by Rony V. Diaz is "Do
not do to others what others can
do to you".
•The story is a metaphor for how
humans can get in their own way
by overthinking things.
•The story suggests that it's better
to trust our instincts and not
overanalyze every little thing.
Prepared by: Akash Agnihotri 25
26. The Centipede’s Dilemma
Ask a centipede which one of its
hundred legs moves the fastest and
it forgets how to move. Reflecting
on what we normally do without
thought ironically worsens
performance. A culture of endless
self-reflection, therapy, and navel
gazing is eroding important life
skills.
Prepared by: Akash Agnihotri 26
27. Next Concept
•Tyranny of Small Decisions
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Prepared by: Akash Agnihotri 27
29. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 29
30. Tyranny of Small Decisions
The tyranny of small decisions is a
phenomenon that occurs when a series
of small decisions, individually
insignificant, cumulatively result in a
larger and significant outcome that is
neither optimal nor desired.
These small decisions, in isolation, may
seem perfectly logical and
understandable.
Prepared by: Akash Agnihotri 30
31. Tyranny of Small Decisions
The tyranny of small decisions can derail
grand strategies slowly and often
imperceptibly.
For example, the smallness of individual
transactions may encourage irrational
consumer choice, because they are too
small to justify the effort of securing good
market information.
Prepared by: Akash Agnihotri 31
32. Tyranny of Small Decisions
The word “tyranny” suggests a
behavioral pattern that occurs more
than just occasionally. The tyranny
of small decisions specifies not only
the behavior (choice) but also its
consequence (negative outcomes).
Prepared by: Akash Agnihotri 32
33. Next Concept
•The Zebra Effect
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Prepared by: Akash Agnihotri 33
35. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 35
36. The Zebra Effect
Zebras are hard to individually study as
it's nearly impossible to track one of
them for long (lost in the striped chaos).
So scientists once put a big red dot on
one zebra so he could be tracked &
studied.
Lions zeroed in on him and hunted him
with ease.
Getting lost among others is a survival
mechanism. Hence the human desire to
conform.
Prepared by: Akash Agnihotri 36
37. The Zebra Effect
The Zebra Effect is a business model
that promotes collaboration,
sustainability, and ethical purpose.
It's a contrast to the unicorn model,
which focuses on profit and disruption.
The idea is that companies can benefit
from forming partnerships with similar
organizations to overcome challenges
and achieve mutual success
Prepared by: Akash Agnihotri 37
38. The Zebra Effect
In simple terms, the "zebra effect" refers to
a phenomenon where stripes, like those on
a zebra, can confuse or deter predators,
such as flies or lions.
The stripes may make it hard for predators
to single out an individual zebra from the
herd, making it less likely to be attacked.
This camouflage-like effect helps zebras
blend in with each other and their
surroundings, increasing their chances of
survival.
Prepared by: Akash Agnihotri 38
39. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 39
40. Why The Ruler Can’t Rule
The executive head can’t implement his
ideas on ground because the
bureaucrats are closer to it, and have
an agenda of their own.
The Tzar of Russia had to deal with the
Deep State too.
Nicholas II: “I never ruled Russia.
10,000 clerks ruled Russia.”
Prepared by: Akash Agnihotri 40
41. Why The Ruler Can’t Rule
“The Ruler Can't Rule" is a phrase often
used to describe situations where a
leader or authority figure faces
significant challenges in effectively
governing or controlling a population.
This phrase reflects the idea that
governing is not simply about issuing
orders or mandates, but also about
securing the consent, cooperation, and
support of those being governed.
Prepared by: Akash Agnihotri 41
42. Why The Ruler Can’t Rule
In simple terms, “The Ruler Can't Rule"
means that sometimes leaders or bosses
can't control things as much as they'd like
to.
This could happen because people don't
agree with them, they resist the leader's
decisions, or because society is too
complicated to control easily.
It shows that being in charge isn't just about
giving orders, but also about getting people
to support you and dealing with all the
different problems that come up.
Prepared by: Akash Agnihotri 42
43. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 43
44. Gall’s Law
A complex system that works is
invariably found to have evolved from a
simple system that worked.
Only fools and modern technocrats try
to create complex systems from
scratch.
Prepared by: Akash Agnihotri 44
45. Gall’s Law
Gall's Law states that all complex
systems that work evolved from simpler
systems that worked.
If you want to build a complex system
that works, build a simpler system first,
and then improve it over time.
Prepared by: Akash Agnihotri 45
46. Gall’s Law
This law, proposed by John Gall in his
book "Systemantics: How Systems
Really Work and How They Fail,"
essentially suggests that successful
complex systems didn't start out
complex; rather, they began as simpler
systems that were effective and
gradually evolved over time through
incremental changes and iterations.
Prepared by: Akash Agnihotri 46
48. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 48
49. Minimal Self Hypothesis
Narcissism is a “strategic retreat” into
the safety of one’s own self.
When the future looks random,
inexplicable, and informationally
overwhelming, people enter survival
mode.
The self becomes “minimal” to reduce
its surface area to pain.
People today are giving up on
commitment of all sorts to conserve
energy for vague and upcoming
disasters.
Prepared by: Akash Agnihotri 49
50. Minimal Self Hypothesis
This hypothesis suggests that this basic
sense of self is not dependent on
complex cognitive processes or higher-
level thinking but is instead a
foundational aspect of human
experience.
It helps us navigate the world and
interact with others by providing a
sense of individual identity and agency.
Prepared by: Akash Agnihotri 50
51. Minimal Self Hypothesis
The Minimal Self Hypothesis is the idea
that every person has a basic
understanding of who they are. It's like
a little voice inside us that helps us
know we're different from others and
have our own thoughts and actions.
This sense of self is really important
because it helps us make sense of the
world and how we fit into it.
Prepared by: Akash Agnihotri 51
52. 10 Concepts that explains the modern
world
•Parkinson’s Law
•Chesterton’s Fence
•The Medici Effect
•The Centipede’s Dilemma
•Tyranny of Small Decisions
•The Zebra Effect
•Why The Ruler Can’t Rule
•Gall’s Law
•Minimal Self Hypothesis
•Tetris Syndrome
Prepared by: Akash Agnihotri 52
53. Tetris Syndrome
The world will eventually start looking
like Tetris blocks if you play the game
too much.
What we do most often becomes the
metaphor through which we look at the
world.
Prepared by: Akash Agnihotri 53
54. Tetris Syndrome
Tetris Effect is a phenomenon that
occurs when someone spends a lot of
time and effort playing the video game
Tetris, which can alter their thoughts,
experiences, and dreams.
People who play Tetris for long periods
of time may see Tetris pieces in their
mind or in their dreams, even when they
close their eyes or walk away from the
game.
For example, they might see falling
blocks in their dreams or notice square
windows and rectangular doors in the
real world.
Prepared by: Akash Agnihotri 54
55. Take Home Message
Most people today are addicted to their
2D phones - and this will hurt the
general aptitude for dealing with the 3D
world.
Prepared by: Akash Agnihotri 55