The European Bioinformatics Institute




                               EMBL-EBI
Katrina Pavelin
Scientific Outreach Officer
                               Services | Research | Training | Industry
katrina@ebi.ac.uk
What is EMBL-EBI?




•   Bioinformatics Research & Service Institute
•   Non-profit organisation
•   Part of the European Molecular Biology Laboratory

                                                        EMBL-EBI
The five branches of EMBL
Heidelberg               Hamburg             Hinxton




• Basic research in     Structural biology   Bioinformatics
  molecular biology
• Administration         Grenoble            Monterotondo
• EMBO


•   1500 staff
•   >60 nationalities
                        Structural biology   Mouse biology




                                                              EMBL-EBI
EMBL-EBI’s Mission
•   To provide freely available data and bioinformatics services to all
    facets of the scientific community in ways that promote scientific
    progress
•   To contribute to the advancement of biology through basic
    investigator-driven research in bioinformatics
•   To provide advanced bioinformatics training to scientists at all levels,
    from PhD students to independent investigators
•   To help disseminate cutting-edge technologies to industry
•   To coordinate biological data provision across Europe




                                                             EMBL-EBI
What is bioinformatics?
• The science of storing,
  retrieving and                                  Growth of raw storage
  analysing large                                at EMBL-EBI (in terabytes)
  amounts of biological                  12000

  information                            10000

                                          8000
• An interdisciplinary

                            Disks (TB)
                                          6000
  science, involving
                                          4000
  biologists, computer
  scientists and                          2000


  mathematicians                             0



• At the heart of modern                                    Year

  biology

                                                                   EMBL-EBI
Services
www.ebi.ac.uk/services




                         EMBL-EBI

                         Services | Research | Training | Industry
Databases: molecules to systems                       Literature and ontologies
   Genomes                                             UKPMC, CiteXplore, GO
    Ensembl
Ensembl Genomes                                           Protein families,
      EGA                                                motifs and domains
  Metagenomics                                                 InterPro
      portal                   Functional
                               genomics
                                                                  Macromolecular
                              ArrayExpress
 Nucleotide sequence                                                 structure
                             Expression Atlas
         ENA                                                           PDBe

         Protein activity
          IntAct, PRIDE                                                  Pathways
                                                                         Reactome
               Protein Sequences
                     UniProt

                            Chemical entities
                                ChEBI
                                                                        Systems
                                      Chemogenomics                    BioModels
                                         ChEMBL                        BioSamples


                                                               EMBL-EBI
EBI’s search service
                                    Access from the
                                    EBI’s homepage



                                              Species selector
                                               allows for easy
                                                 comparison




Data organised
according to:
• gene                     Explore data,
• expression              return easily to
• protein                   your results
• structure
• literature

                                             EMBL-EBI
Research
www.ebi.ac.uk/groups




                       EMBL-EBI

                       Services | Research | Training | Industry
Key facts about research at EMBL-EBI
• A unique
  environment for
  bioinformatics
  research
• Nine dedicated
  research groups
• Services teams also
  carry out R&D
• Research and
  services are mutually
  supportive

                                  EMBL-EBI
Training
www.ebi.ac.uk/training




                         EMBL-EBI

                         Services | Research | Training | Industry
Pre- and postdocs at EMBL-EBI




• EMBL International PhD Programme
• Postdoctoral fellowships:
   • EIPOD – EMBL-sponsored interdisciplinary fellowships
   • ESPOD – EBI–Sanger combined experimental and
     computational fellowships

                                                 EMBL-EBI
EMBL-EBI
1
4
    EMBL-EBI
Thank you!


             EMBL-EBI

1 introduction to_the_ebi_(katrina_pavelin)

  • 1.
    The European BioinformaticsInstitute EMBL-EBI Katrina Pavelin Scientific Outreach Officer Services | Research | Training | Industry katrina@ebi.ac.uk
  • 2.
    What is EMBL-EBI? • Bioinformatics Research & Service Institute • Non-profit organisation • Part of the European Molecular Biology Laboratory EMBL-EBI
  • 3.
    The five branchesof EMBL Heidelberg Hamburg Hinxton • Basic research in Structural biology Bioinformatics molecular biology • Administration Grenoble Monterotondo • EMBO • 1500 staff • >60 nationalities Structural biology Mouse biology EMBL-EBI
  • 4.
    EMBL-EBI’s Mission • To provide freely available data and bioinformatics services to all facets of the scientific community in ways that promote scientific progress • To contribute to the advancement of biology through basic investigator-driven research in bioinformatics • To provide advanced bioinformatics training to scientists at all levels, from PhD students to independent investigators • To help disseminate cutting-edge technologies to industry • To coordinate biological data provision across Europe EMBL-EBI
  • 5.
    What is bioinformatics? •The science of storing, retrieving and Growth of raw storage analysing large at EMBL-EBI (in terabytes) amounts of biological 12000 information 10000 8000 • An interdisciplinary Disks (TB) 6000 science, involving 4000 biologists, computer scientists and 2000 mathematicians 0 • At the heart of modern Year biology EMBL-EBI
  • 6.
    Services www.ebi.ac.uk/services EMBL-EBI Services | Research | Training | Industry
  • 7.
    Databases: molecules tosystems Literature and ontologies Genomes UKPMC, CiteXplore, GO Ensembl Ensembl Genomes Protein families, EGA motifs and domains Metagenomics InterPro portal Functional genomics Macromolecular ArrayExpress Nucleotide sequence structure Expression Atlas ENA PDBe Protein activity IntAct, PRIDE Pathways Reactome Protein Sequences UniProt Chemical entities ChEBI Systems Chemogenomics BioModels ChEMBL BioSamples EMBL-EBI
  • 8.
    EBI’s search service Access from the EBI’s homepage Species selector allows for easy comparison Data organised according to: • gene Explore data, • expression return easily to • protein your results • structure • literature EMBL-EBI
  • 9.
    Research www.ebi.ac.uk/groups EMBL-EBI Services | Research | Training | Industry
  • 10.
    Key facts aboutresearch at EMBL-EBI • A unique environment for bioinformatics research • Nine dedicated research groups • Services teams also carry out R&D • Research and services are mutually supportive EMBL-EBI
  • 11.
    Training www.ebi.ac.uk/training EMBL-EBI Services | Research | Training | Industry
  • 12.
    Pre- and postdocsat EMBL-EBI • EMBL International PhD Programme • Postdoctoral fellowships: • EIPOD – EMBL-sponsored interdisciplinary fellowships • ESPOD – EBI–Sanger combined experimental and computational fellowships EMBL-EBI
  • 13.
  • 14.
    1 4 EMBL-EBI
  • 15.
    Thank you! EMBL-EBI