2. •Outlines of the lecture:
• Introduction to histopathology and define the terms related to it
• Learning the application of histopathology
• Learning types of tissue samples
• Learning types of biopsies and autopsies
3. THE CELL
• Is the structural and functional unit of the body.
4. A TISSUE
• Is a mass of similar cells and cell products that arise from
the same region of the embryo and work together to
perform a specific structural or physiological role in an
organ.”
5. An ORGAN
• An organ is a group of similar or different tissues
performed one or multiple functions .e.g. liver, kidney.
6. A SYSTEM
• A system is a group of organs in the body.
8. HISTOLOGY
Is the study of tissues and organs through the examination
of the Microscopical architecture, and the relationship
between cells and tissue types.
9. CYTOLOGY
• Cytology is the scientific study of cells obtained from
tissues or body secretions to identify disease
13. A BIOPSY
• A representative sample of tissue or organ from living case
for histological evaluation ( diagnosis) to ascertain further
management.
14. An AUTOPSY
representative sample of tissue from dead case for
histological evaluation.
to determine the cause and manner of death and to
evaluate any disease or injury that may be present.
15. Tissue biopsy used for
Examine tissue for disease.
To match organ before a transplantation.
16. TYPES OF TISSUE BIOPSY
Excisional biopsy
Performed when the whole lesion is excised to give
histological diagnosis. e.g. skin lesion.
19. Core biopsy
• Performed by using circular cutting needle= core of
tissue.
• A core biopsy Directed by ultra sound or C.T guided. e.g.
renal, liver biopsy.
Fine-needle aspiration.
• A long, thin needle is inserted into the suspicious area.
22. Endoscopic biopsy:
• Performed in many sites e.g. GIT.
• Endoscopic biopsy associated with endoscopy.
23.
24. Punch biopsy:
• Skin biopsy in which a circular tool is used to remove a small
section of skin's deeper layers.
Shave biopsy:
• Skin biopsy in which tool similar to a razor is used to scrape
the surface of the skin.
27. Dilation and curettage (D&C) biopsy.
• Is a procedure in which the cervix of the uterus is
expanded (dilated) so that the uterine lining
(endometrium) can be removed with a spoon-
shaped instrument called a cruet or curette.
28. TYPES OF TISSUE AUTOPSY
Forensic autopsy:
For legal purpose
Clinical/ academic autopsy:
For research and study purposes.