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1. Explain the role of each of the following in HIV infection -protease: essential for assembling the
virus during the last step of the infection -reverse transcriptases, an enzyme that helos conver
RNA to DNA -CD4 receptors: - RNA polymerase -integrase - ribosomes and golgi apparatus2.
What is a retrovirus? Why is it more difficult to develop a vaccine for a retrovirus? 3. What proteins
come packaged in the virus? 4. Drugs such as AZT work by inhibiting the function of reverse
transcriptase. Integrase Strand Transfer Inhibitors (INSTI) are a class of antiretroviral drugs
designed to block the action of integrasen Sketch a model showing how AZT and INSTI work. 5.
Another class of antiviral drugs are called protease inhibitor. Explain how this type of drug would
work. 6. Viruses like smallpox and polio contain DNA instead of RNA. That means that some of
the steps in the HIV model are no longer necessary. Sketch a model on the back of your coloring
page that would show how a DNA virus would work. Include any proteins or structures that would
still be necessary forviral infection and replications. Remember that models do not need to be
physically accurate, symbols are acceptable to represent structures. It is also acceptable to use
the HIV model as a template for your new design. Color isn't necessary, but it may make the
model easier to understand.

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1 Explain the role of each of the following in HIV infectio.pdf

  • 1. 1. Explain the role of each of the following in HIV infection -protease: essential for assembling the virus during the last step of the infection -reverse transcriptases, an enzyme that helos conver RNA to DNA -CD4 receptors: - RNA polymerase -integrase - ribosomes and golgi apparatus2. What is a retrovirus? Why is it more difficult to develop a vaccine for a retrovirus? 3. What proteins come packaged in the virus? 4. Drugs such as AZT work by inhibiting the function of reverse transcriptase. Integrase Strand Transfer Inhibitors (INSTI) are a class of antiretroviral drugs designed to block the action of integrasen Sketch a model showing how AZT and INSTI work. 5. Another class of antiviral drugs are called protease inhibitor. Explain how this type of drug would work. 6. Viruses like smallpox and polio contain DNA instead of RNA. That means that some of the steps in the HIV model are no longer necessary. Sketch a model on the back of your coloring page that would show how a DNA virus would work. Include any proteins or structures that would still be necessary forviral infection and replications. Remember that models do not need to be physically accurate, symbols are acceptable to represent structures. It is also acceptable to use the HIV model as a template for your new design. Color isn't necessary, but it may make the model easier to understand.