During the Industrial Revolution, workers faced difficult conditions such as long hours of manual labor in unsanitary factories from a young age. Many workers operated complex machinery without training, leading to increased accidents. Diseases like tuberculosis, cholera, and alcoholism spread rapidly in overcrowded living and working conditions with poor hygiene. Byssinosis, a deadly lung disease caused by inhaling textile fibers, was also common due to lack of safety standards in factories at this time.