The document discusses the Expanded Program on Immunization (EPI) which aims to reduce morbidity and mortality from diseases like diphtheria, pertussis, tetanus, tuberculosis, poliomyelitis, and measles through increased immunization coverage of children. It provides details on vaccine contents, proper storage temperatures to maintain potency, recommended immunization schedules including minimum ages and number of doses, and routes of administration for vaccines like BCG, DPT, polio, measles, hepatitis B, and tetanus toxoid.

1. EXPANDED
PROGRAM ON
IMMUNIZATION
Prepared By: Rommel Luis C. Israel III

2. EXPANDED PROGRAM ON IMMUNIZATION
 AIM:
The reduction of the rate of morbidity &
mortality from DIPTHERIA, PERTUSSIS,
TETANUS, TUBERCOLOSIS, POLIOMYELITIS &
MEASLES through increased immunization
coverage of Fully immunized children.
PROCLAMATION NO. 6
Implementing a United Nations Goal on Universal
Child Immunization by 1990.

3. Vaccine Contents Form Dose Container
Condition when exposed to
heat/ freezing
ADMINISTRATION OF VACCINE PREPARING VACCINES FOR ADMINISTRATION
1. BCG
live attenuated
bacterial vaccines;
Bacillus Calmette &
Guerin
freeze dried &
reconstituted w/ a
special diluent
20 dose/ampule
50 dose/ampule
destroyed by heat, sunlight but
not by freezing
> destroyed by freezing heat
>damaged by heat, freezing
> damaged by heat
3. Measles live attenuated virus
freeze dried &
reconstituted w/ a
special diluent 10 dose/vial
> easily damaged by heat but
not destroyed by freezing
2. DPT
"D"
"P"
"T"
"D"> toxoid w/c is a
weakened toxin
"P"> killed bacteria
"T"> toxoid w/c is a
weakened toxin liquid 10 dose/vial or 20 dose/vial
4. Polio
vaccines live attenuated virus 20 or 25 dose/special bottle
>easily damaged by heat but
not destroyed by freezingliquid
>damaged by heat or freezing
6. Hepatitis
B
Plasma derived; RNA
recombinant liquid
single dose/vial
10 dose/vial >damaged by heat or freezing
5. Tetanus
Toxoid weakened toxin liquid 20 dose/ vial

4. Vaccine Contents Form Dose Container
Condition when exposed to
heat/ freezing
ADMINISTRATION OF VACCINE PREPARING VACCINES FOR ADMINISTRATION
1. BCG
live attenuated
bacterial vaccines;
Bacillus Calmette &
Guerin
freeze dried &
reconstituted w/ a
special diluent
20 dose/ampule
50 dose/ampule
destroyed by heat, sunlight but
not by freezing
> destroyed by freezing heat
>damaged by heat, freezing
> damaged by heat
3. Measles live attenuated virus
freeze dried &
reconstituted w/ a
special diluent 10 dose/vial
> easily damaged by heat but
not destroyed by freezing
2. DPT
"D"
"P"
"T"
"D"> toxoid w/c is a
weakened toxin
"P"> killed bacteria
"T"> toxoid w/c is a
weakened toxin liquid 10 dose/vial or 20 dose/vial
4. Polio
vaccines live attenuated virus 20 or 25 dose/special bottle
>easily damaged by heat but
not destroyed by freezingliquid
>damaged by heat or freezing
6. Hepatitis
B
Plasma derived; RNA
recombinant liquid
single dose/vial
10 dose/vial >damaged by heat or freezing
5. Tetanus
Toxoid weakened toxin liquid 20 dose/ vial

5. THE COLD CHAIN
 A system for
ensuring the
potency of a
vaccine from the
time of
manufacture to the
time it is given to a
child or a pregnant
woman.

6. Type of Vaccine Storage Temperature
Most
sensitive to
heat
Oral Polio
Measls (freeze
dried)
(-15 C) to (-25 C)
(-15 C) to (-25 C)
DPT 2 C to 8 C
Least
sensitive to
heat
BCG (freeze dried)
Tetanus Toxoid
2 C to 8 C
2 C to 8 C
RECOMMENDED STORAGE TEMPERATURE OF
E.P.I. VACCINES:

7. Vaccine Minimum Age at 1st Dose Number of Doses Minimum IntervalBetween Doses Reason
IMMUNIZATION SCHEDULE
Birth or anytime afterbirth1. BCG 1
BCG given at ther earliest possible age
protects against the possibility ofinfection
from other family members.
An early start with DPTreduces the
chance ofsevere pertussis.2. DPT 6 weeks 3 4 weeks
An early start ofHepa B induces the
chance ofbeing infected and become a
carrier
3. OPV 6 weeks 3 4 weeks
At least 80% ofmeasles can be prevented
by immunization at nthis age.
The extent ofprotection against polio is
increased thje earlier the OPV is given.
4. Hepa B
5. Measles
6 weeks
9 months
3
1
4 weeks

8. Vaccine Dose Route of Administration Site of Administration
ADMINISTRATION OF VACCINES
BCG
infants: 0.05 ml school
entrants:0.1 ml
intradermal
intradermal
Right deltoid of the arm
Left deltoid of the arm
DPT
Hepatitis B 0.5 ml intramuscular
upper outer portion of
the thigh
Polio
2 drops, or depending on
manufacturer's instructions oral mouth
Measles 0.5 ml subcutaneous
outer part of the upper
arm
Tetanus
Toxoid 0.5 ml deep intramuscular
deltoid region of the
upper arm